| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Arendt, D Henning, J A Gray, R Marchbank. Loss of neurons in the rat basal forebrain cholinergic projection system after prolonged intake of ethanol. Brain research bulletin. vol 21. issue 4. 1989-02-22. PMID:2850095. |
activity of choline acetyltransferase (chat) and ache in the basal forebrain was simultaneously reduced to 74% and 81% and content of acetylcholine (ach) to 56% of control values respectively. |
1989-02-22 |
2023-08-11 |
rat |
| V E Baburin, L V Suvorov. [Enzymatic activity of neurons of various parts of the digestive tube in postnatal ontogenesis of the rat (cytophotometric histochemical study)]. Arkhiv anatomii, gistologii i embriologii. vol 95. issue 8. 1989-02-14. PMID:3214303. |
glucose-6-phosphatase dehydrogenase, nadph-dehydrogenase, acid phosphatase, alkaline phosphatase (aph), monoamine oxidase, acetylcholine esterase (ache) have been revealed in 19-20-day-old embryos, in 1-, 21-, 30-day-old rats and in mature rats. |
1989-02-14 |
2023-08-11 |
rat |
| A Tokunag. Superior olivary and lateral lemniscal neurons projecting to the cochlea in the guinea pig. Neuroscience research. vol 6. issue 1. 1989-01-25. PMID:2462200. |
a combination of acetylcholine esterase (ache) histochemistry with the tracing of retrograde axonal transport of a fluorescent dye (dapi) revealed that vll neurons projecting to the cochlea, as well as about 85% of lso neurons projecting to the ipsilateral cochlea, were ache-positive. |
1989-01-25 |
2023-08-11 |
Not clear |
| K K Hreib, D L Rosene, M B Mos. Basal forebrain efferents to the medial dorsal thalamic nucleus in the rhesus monkey. The Journal of comparative neurology. vol 277. issue 3. 1989-01-24. PMID:2461974. |
in order to determine the extent of the cholinergic input to mdmc from the bf, one of the hrp cases was processed for the simultaneous visualization of hrp, and acetylcholinesterase (ache), the hydrolytic enzyme for acetylcholine, and a second case was processed for simultaneous visualization of hrp, and choline acetyltransferase (chat), the synthetic enzyme for acetylcholine. |
1989-01-24 |
2023-08-11 |
monkey |
| R Defez, P Brache. Pheochromocytoma PC12 cells influence the differentiation of co-cultured skeletal myotubes. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 4. issue 2. 1988-10-27. PMID:3455581. |
essentially all the tight contacts established between pc12 cells and myotubes were characterized by a receptor cluster and, in some cases, by an aggregate of an acetylcholine esterase (ache), as visualized by immunohistochemistry. |
1988-10-27 |
2023-08-11 |
rat |
| R Quirio. Characterization and autoradiographic distribution of hemicholinium-3 high-affinity choline uptake sites in mammalian brain. Synapse (New York, N.Y.). vol 1. issue 4. 1988-10-20. PMID:3138770. |
this hypothesis is also supported by quantitative autoradiographic data which demonstrate that the discrete distribution of [3h]hc-3 binding sites correlates very well with the known distribution of other cholinergic markers such as choline acetyltransferase (chat), acetylcholinesterase (ache), hacu, and [3h]ah-5183 (blocker of the vesicular transport of acetylcholine). |
1988-10-20 |
2023-08-11 |
rat |
| H Kobayashi, A Yuyama, T Ohkawa, T Kajit. Effect of single or chronic injection with a carbamate, propoxur, on the brain cholinergic system and behavior of mice. Japanese journal of pharmacology. vol 47. issue 1. 1988-10-06. PMID:3411818. |
single injection caused an increase in brain acetylcholine (ach) content at 10 and 60 min; and it caused decreases in acetylcholinesterase (ache) activity at 10, 60 and 180 min, high-affinity choline uptake into synaptosomes at 10 and 60 min, and [3h]quinuclidinyl benzilate (qnb) binding at 10 min without causing any change in choline acetyltransferase (chat) activity. |
1988-10-06 |
2023-08-11 |
mouse |
| T M Turpaev, M N Semenov. Recovery of acetylcholinesterase activity after irreversible inhibition by organophosphorous compounds in embryonic development. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 89. issue 2. 1988-08-12. PMID:2898993. |
it is possible that acetylcholine accumulated as a result of partial ache inhibition is responsible for the compensatory increase in ache biosynthesis. |
1988-08-12 |
2023-08-11 |
chicken |
| S A Greenfield, J J Jack, A T Last, M Frenc. An electrophysiological action of acetylcholinesterase independent of its catalytic site. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:3384044. |
these effects seem to be unrelated to hydrolysis of acetylcholine, but the underlying cellular mechanisms of these actions of ache are unknown. |
1988-07-29 |
2023-08-11 |
Not clear |
| S A Greenfield, J J Jack, A T Last, M Frenc. An electrophysiological action of acetylcholinesterase independent of its catalytic site. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:3384044. |
it is concluded that ache can modify the membrane properties of nigrostriatal neurones in a way that is independent of its ability to hydrolyse acetylcholine. |
1988-07-29 |
2023-08-11 |
Not clear |
| S J Kish, L Schut, J Simmons, J Gilbert, L J Chang, M Rebbeto. Brain acetylcholinesterase activity is markedly reduced in dominantly-inherited olivopontocerebellar atrophy. Journal of neurology, neurosurgery, and psychiatry. vol 51. issue 4. 1988-07-15. PMID:3164041. |
the activity was measured of the acetylcholine catabolising enzyme acetylcholinesterase (ache) in brain after necropsy of seven patients from one established pedigree with dominantly-inherited olivopontocerebellar atrophy (opca), a cerebellar ataxia disorder in which neuropathological changes are assumed to be primarily restricted to cerebellum, lower brain stem and spinal cord. |
1988-07-15 |
2023-08-11 |
Not clear |
| P Aa. The toxic effect of an AChE-inhibitor on the cholinergic nervous system in airway smooth muscle. Toxicology. vol 49. issue 1. 1988-06-30. PMID:3376127. |
excessive cholinergic stimulation of presynaptic muscarinic cholinergic receptors, due to complete inhibition of acetylcholinesterase (ache) by o-(1,2,2-trimethylpropyl)-methyl-phosphonofluoridate (soman), reduced the release of acetylcholine (ach) from cholinergic nerves in rat bronchi by almost 25%. |
1988-06-30 |
2023-08-11 |
rat |
| C R Lupica, R F Berma. Atropine slows olfactory bulb kindling while diminished cholinergic innervation does not. Brain research bulletin. vol 20. issue 2. 1988-06-24. PMID:3370504. |
despite the depletion of acetylcholine (ach), as determined by acetylcholinesterase (ache) and choline acetyltransferase (chat) assays, no significant alterations in kindling parameters were observed. |
1988-06-24 |
2023-08-11 |
rat |
| H Kobayashi, A Yuyama, M Ishihara, N Matsusak. Effects of arsenic on cholinergic parameters in brain in vitro. Neuropharmacology. vol 26. issue 12. 1988-04-07. PMID:3437937. |
arsenite, at concentrations greater than 10(-4) m, inhibited depolarized and nondepolarized release of acetylcholine (ach) from cerebral slices, the synthesis of ach in the slices, high-affinity uptake of choline into synaptosomes and activity of acetylcholinesterase (ache). |
1988-04-07 |
2023-08-11 |
mouse |
| L Lärkfors, I Strömberg, T Ebendal, L Olso. Nerve growth factor protein level increases in the adult rat hippocampus after a specific cholinergic lesion. Journal of neuroscience research. vol 18. issue 4. 1988-04-01. PMID:3437470. |
using enzyme immunoassay and acetylcholine esterase (ache) histochemistry we have now studied the levels of ngf and ache after a specific cholinergic lesion, transection of the fimbria fornix comprising the major cholinergic input to hippocampus. |
1988-04-01 |
2023-08-11 |
rat |
| P De Sarno, E Giacobini, M Downe. Release of acetylcholinesterase from the caudate nucleus of the rat. Journal of neuroscience research. vol 18. issue 4. 1988-04-01. PMID:3437472. |
a comparison of acetylcholine (ach) and ache release showed that maximal 3h-outflow and ache release occurred at the same frequency (5 hz), but the onset of ache release was delayed. |
1988-04-01 |
2023-08-11 |
rat |
| B Pilo, S P Meha. Effect of cholinesterase inhibitors on acetylcholine and insulin induced glucose uptake and certain hepatic enzymes in pigeon liver: an in vitro study. Indian journal of physiology and pharmacology. vol 31. issue 3. 1988-03-16. PMID:3323058. |
in the present study the action of these three inhibitors of ache alone as well as in combination with insulin and acetylcholine on in vitro glucose uptake by pigeon liver slices was investigated. |
1988-03-16 |
2023-08-11 |
pigeon |
| B A Chase, D R Kanke. On the role of normal acetylcholine metabolism in the formation and maintenance of the Drosophila nervous system. Developmental biology. vol 125. issue 2. 1988-03-08. PMID:3123293. |
by using mutations at the ace and cha loci, which respectively encode the degradative and synthetic enzymes for acetylcholine (ach), acetylcholinesterase (ache), and choline acetyltransferase (chat), we have been able to disrupt acetylcholine metabolism in situ. |
1988-03-08 |
2023-08-11 |
drosophila_melanogaster |
| M N Semenova, T M Turpae. [Recovery of acetylcholinesterase activity in the axolotl embryo following inhibition with the organophosphorus inhibitor Gd-7]. Ontogenez. vol 18. issue 5. 1988-02-16. PMID:3696676. |
acetylcholine, accumulating in the organism at partial inactivation of ache by phosphororganic inhibitor may participate in this mechanism. |
1988-02-16 |
2023-08-11 |
Not clear |
| R M Nitkin, M A Smith, C Magill, J R Fallon, Y M Yao, B G Wallace, U J McMaha. Identification of agrin, a synaptic organizing protein from Torpedo electric organ. The Journal of cell biology. vol 105. issue 6 Pt 1. 1988-02-05. PMID:2826489. |
extracts of the electric organ of torpedo californica contain a proteinaceous factor that causes the formation of patches on cultured myotubes at which acetylcholine receptors (achr), acetylcholinesterase (ache), and butyrylcholinesterase (buche) are concentrated. |
1988-02-05 |
2023-08-11 |
Not clear |