| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Greenfield, J J Jack, A T Last, M Frenc. An electrophysiological action of acetylcholinesterase independent of its catalytic site. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:3384044. |
it is concluded that ache can modify the membrane properties of nigrostriatal neurones in a way that is independent of its ability to hydrolyse acetylcholine. |
1988-07-29 |
2023-08-11 |
Not clear |
| S J Kish, L Schut, J Simmons, J Gilbert, L J Chang, M Rebbeto. Brain acetylcholinesterase activity is markedly reduced in dominantly-inherited olivopontocerebellar atrophy. Journal of neurology, neurosurgery, and psychiatry. vol 51. issue 4. 1988-07-15. PMID:3164041. |
the activity was measured of the acetylcholine catabolising enzyme acetylcholinesterase (ache) in brain after necropsy of seven patients from one established pedigree with dominantly-inherited olivopontocerebellar atrophy (opca), a cerebellar ataxia disorder in which neuropathological changes are assumed to be primarily restricted to cerebellum, lower brain stem and spinal cord. |
1988-07-15 |
2023-08-11 |
Not clear |
| P Aa. The toxic effect of an AChE-inhibitor on the cholinergic nervous system in airway smooth muscle. Toxicology. vol 49. issue 1. 1988-06-30. PMID:3376127. |
excessive cholinergic stimulation of presynaptic muscarinic cholinergic receptors, due to complete inhibition of acetylcholinesterase (ache) by o-(1,2,2-trimethylpropyl)-methyl-phosphonofluoridate (soman), reduced the release of acetylcholine (ach) from cholinergic nerves in rat bronchi by almost 25%. |
1988-06-30 |
2023-08-11 |
rat |
| C R Lupica, R F Berma. Atropine slows olfactory bulb kindling while diminished cholinergic innervation does not. Brain research bulletin. vol 20. issue 2. 1988-06-24. PMID:3370504. |
despite the depletion of acetylcholine (ach), as determined by acetylcholinesterase (ache) and choline acetyltransferase (chat) assays, no significant alterations in kindling parameters were observed. |
1988-06-24 |
2023-08-11 |
rat |
| H Kobayashi, A Yuyama, M Ishihara, N Matsusak. Effects of arsenic on cholinergic parameters in brain in vitro. Neuropharmacology. vol 26. issue 12. 1988-04-07. PMID:3437937. |
arsenite, at concentrations greater than 10(-4) m, inhibited depolarized and nondepolarized release of acetylcholine (ach) from cerebral slices, the synthesis of ach in the slices, high-affinity uptake of choline into synaptosomes and activity of acetylcholinesterase (ache). |
1988-04-07 |
2023-08-11 |
mouse |
| L Lärkfors, I Strömberg, T Ebendal, L Olso. Nerve growth factor protein level increases in the adult rat hippocampus after a specific cholinergic lesion. Journal of neuroscience research. vol 18. issue 4. 1988-04-01. PMID:3437470. |
using enzyme immunoassay and acetylcholine esterase (ache) histochemistry we have now studied the levels of ngf and ache after a specific cholinergic lesion, transection of the fimbria fornix comprising the major cholinergic input to hippocampus. |
1988-04-01 |
2023-08-11 |
rat |
| P De Sarno, E Giacobini, M Downe. Release of acetylcholinesterase from the caudate nucleus of the rat. Journal of neuroscience research. vol 18. issue 4. 1988-04-01. PMID:3437472. |
a comparison of acetylcholine (ach) and ache release showed that maximal 3h-outflow and ache release occurred at the same frequency (5 hz), but the onset of ache release was delayed. |
1988-04-01 |
2023-08-11 |
rat |
| B Pilo, S P Meha. Effect of cholinesterase inhibitors on acetylcholine and insulin induced glucose uptake and certain hepatic enzymes in pigeon liver: an in vitro study. Indian journal of physiology and pharmacology. vol 31. issue 3. 1988-03-16. PMID:3323058. |
in the present study the action of these three inhibitors of ache alone as well as in combination with insulin and acetylcholine on in vitro glucose uptake by pigeon liver slices was investigated. |
1988-03-16 |
2023-08-11 |
pigeon |
| B A Chase, D R Kanke. On the role of normal acetylcholine metabolism in the formation and maintenance of the Drosophila nervous system. Developmental biology. vol 125. issue 2. 1988-03-08. PMID:3123293. |
by using mutations at the ace and cha loci, which respectively encode the degradative and synthetic enzymes for acetylcholine (ach), acetylcholinesterase (ache), and choline acetyltransferase (chat), we have been able to disrupt acetylcholine metabolism in situ. |
1988-03-08 |
2023-08-11 |
drosophila_melanogaster |
| M N Semenova, T M Turpae. [Recovery of acetylcholinesterase activity in the axolotl embryo following inhibition with the organophosphorus inhibitor Gd-7]. Ontogenez. vol 18. issue 5. 1988-02-16. PMID:3696676. |
acetylcholine, accumulating in the organism at partial inactivation of ache by phosphororganic inhibitor may participate in this mechanism. |
1988-02-16 |
2023-08-11 |
Not clear |
| R M Nitkin, M A Smith, C Magill, J R Fallon, Y M Yao, B G Wallace, U J McMaha. Identification of agrin, a synaptic organizing protein from Torpedo electric organ. The Journal of cell biology. vol 105. issue 6 Pt 1. 1988-02-05. PMID:2826489. |
extracts of the electric organ of torpedo californica contain a proteinaceous factor that causes the formation of patches on cultured myotubes at which acetylcholine receptors (achr), acetylcholinesterase (ache), and butyrylcholinesterase (buche) are concentrated. |
1988-02-05 |
2023-08-11 |
Not clear |
| A J Bircher, W Meier-Rug. Aquagenic pruritus. Water-induced activation of acetylcholinesterase. Archives of dermatology. vol 124. issue 1. 1988-01-27. PMID:3337547. |
in ap and polycythemia rubra vera after water exposure a significantly increased ache activity suggesting acetylcholine release was observed, whereas in the patient with cold urticaria and the controls, a significant decrease was noted. |
1988-01-27 |
2023-08-11 |
human |
| A W Kirby, T H Harding, R W Wile. Recovery of the visual evoked response in the cat following administration of diisopropylfluorophosphate, an irreversible cholinesterase inhibitor. Life sciences. vol 41. issue 24. 1988-01-25. PMID:3695800. |
since atropine sulfate provided at least partial recovery of the ver following dfp without affecting ache inhibition, an accumulation of acetylcholine (ach) probably is involved in the initial visual loss. |
1988-01-25 |
2023-08-11 |
cat |
| E Bartha, J Szelényi, K Szilágyi, V Venter, N T Thu Ha, P Páldi-Haris, S Hollá. Altered lymphocyte acetylcholinesterase activity in patients with senile dementia. Neuroscience letters. vol 79. issue 1-2. 1987-12-09. PMID:3499586. |
the ache activity of lymphocytes may thus be a useful marker to follow the alterations in the metabolism of acetylcholine (ach) in the central nervous system (cns) of different types of dementia. |
1987-12-09 |
2023-08-11 |
human |
| C R Schätz, R W Ve. High-resolution localization of acetylcholinesterase at the rat neuromuscular junction. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 35. issue 11. 1987-11-20. PMID:3655326. |
to overcome the limited ultrastructural resolution of conventional acetylcholinesterase (ache) ultrahistochemistry, acetylcholine (atch) was used to reduce the rate of enzymic thiocholine liberation. |
1987-11-20 |
2023-08-11 |
rat |
| S J Begum, M M Reddy, K Indira, K S Swam. Effect of dieldrin on catalytic potential of field mouse Mus booduga brain acetylcholinesterase. Archives internationales de physiologie et de biochimie. vol 95. issue 2. 1987-11-17. PMID:2444176. |
fall in the activity potential of ache may account for the interference of dieldrin or its metabolites with the acetylcholine (ach)--ache system and deserve consideration in contributing to the neurotoxicity. |
1987-11-17 |
2023-08-11 |
mouse |
| M Simonneau, L Tau. Properties of miniature postsynaptic currents during depolarization-induced release at a cholinergic neuroneuronal synapse. Cellular and molecular neurobiology. vol 7. issue 2. 1987-11-16. PMID:3652114. |
power spectra obtained after the application of inhibitors of acetylcholinesterase (ache), with or without curare, suggested that acetylcholine (ach) does not accumulate during large depolarizations. |
1987-11-16 |
2023-08-11 |
aplysia |
| I S Delamanche, P Mailly, C Bouchau. [Organophosphorus compounds as tools for the pharmaco-histochemical study of cholinesterase in the rat striatum]. Archives d'anatomie microscopique et de morphologie experimentale. vol 75. issue 3. 1987-10-06. PMID:3631954. |
a series of organophosphorous compounds (op) was tested using a pharmacohistochemical method applied in vitro on the rat striatum, the central structure which contains the highest levels of acetylcholine and its metabolic enzymes; the op showed a great variety of action towards the specific cholinesterase (ache) and non-specific cholinesterase (buche). |
1987-10-06 |
2023-08-11 |
rat |
| A W Spira, T J Millar, I Ishimoto, M L Epstein, C D Johnson, J L Dahl, I G Morga. Localization of choline acetyltransferase-like immunoreactivity in the embryonic chick retina. The Journal of comparative neurology. vol 260. issue 4. 1987-08-28. PMID:3301917. |
putative sites of acetylcholine synthesis in the retina of the embryonic and posthatched chick were localized immunohistochemically with antisera to choline acetyltransferase; the resultant choline acetyltransferase-like immunoreactivity (chat-ir) was compared to demonstrated sites of acetyltransferase (ache) activity, and changes were followed in localization during development. |
1987-08-28 |
2023-08-11 |
chicken |
| M M Heitkemper, J F Shave. Adrenalectomy and pentagastrin effects on gastrointestinal cholinergic enzyme activities. Biology of the neonate. vol 51. issue 5. 1987-08-11. PMID:3593809. |
the present study examined the effects of pentagastrin and adrenalectomy on choline acetyltransferase (chat) and acetylcholine esterase (ache), enzymes which synthesize and degrade acetylcholine in the rat gastrointestinal tract. |
1987-08-11 |
2023-08-11 |
rat |