| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D F Sharman, T R Coope. A semi-automated fluorimetric method for measuring acetylcholinesterase activity in small volumes of cerebrospinal fluid and tissue extracts using acetylcholine as substrate. Journal of neuroscience methods. vol 16. issue 4. 1986-09-17. PMID:3736119. |
the method is based on the measurement of hydrogen peroxide, formed by the oxidation of choline resulting from the action of ache on acetylcholine, by means of horseradish peroxidase and 4-hydroxy-3-methoxyphenylacetic acid (hva) to yield a fluorescent derivative. |
1986-09-17 |
2023-08-11 |
Not clear |
| M N Semenova, T M Turpaev, I N Sokolov, S N Lyzlov. [Recovery of the acetylcholinesterase activity in a monolayer culture of chick myoblasts after irreversible inhibition by an organophosphorus inhibitor]. Ontogenez. vol 17. issue 3. 1986-08-18. PMID:3725290. |
the recovery of the acetylcholine esterase (ache) activity after the irreversible inhibition with an organophosphorus inhibitor b-156 was studied in a developing monolayer culture of chick myoblasts. |
1986-08-18 |
2023-08-11 |
chicken |
| J Slavíková, S Tuce. Postnatal changes in the activities of acetylcholinesterase and butyrylcholinesterase in rat heart atria. Physiologia Bohemoslovaca. vol 35. issue 1. 1986-06-06. PMID:2939475. |
since ache is known to be specifically involved in the termination of the action of acetylcholine in the sinoatrial node, the observed postnatal changes in its activity are likely to play a role in the postnatal development of cardiac parasympathetic control. |
1986-06-06 |
2023-08-11 |
rat |
| T Kita, T Hata, T Higashiguchi, E Itoh, A Kawabat. Changes of total acetylcholine content and the activity of related enzymes in SART (repeated cold)-stressed rat brain and duodenum. Japanese journal of pharmacology. vol 40. issue 1. 1986-05-15. PMID:3959351. |
in sart-stressed rats regarded as pathologically diseased model animals with vagotonic-type autonomic imbalance, a decrease of total acetylcholine (t-ach) content and enhancements of choline acetyltransferase (cat) and acetylcholinesterase (ache) activities were recognized in the basal ganglia and hypothalamus. |
1986-05-15 |
2023-08-11 |
rat |
| M M Heitkemper, J F Shave. Pentagastrin on neurotransmitter enzyme activities in the rat gastrointestinal tract. The American journal of physiology. vol 250. issue 4 Pt 1. 1986-05-15. PMID:3963198. |
the effects of three doses (5, 100, and 250 micrograms/kg) of pentagastrin on the activities of choline acetyltransferase (chat) and acetylcholine esterase (ache), the neurotransmitter enzymes that synthesize and degrade acetylcholine, and monoamine oxidase (mao), the degradation enzyme for catecholamines, were investigated. |
1986-05-15 |
2023-08-11 |
rat |
| K Komori, H Suzuk. Distribution and properties of excitatory and inhibitory junction potentials in circular muscle of the guinea-pig stomach. The Journal of physiology. vol 370. 1986-04-30. PMID:3007747. |
after inhibition of acetylcholine esterase (ache) by physostigmine or neostigmine, nerve stimulation evoked an enhanced e.j.p., and then produced a sustained depolarization with a duration of 3-5 s in the fundus region, while the amplitude of slow waves after nerve stimulation was further enhanced in the antrum region. |
1986-04-30 |
2023-08-11 |
Not clear |
| E B Fishman, G C Siek, R D MacCallum, E D Bird, L Volicer, J K Marqui. Distribution of the molecular forms of acetylcholinesterase in human brain: alterations in dementia of the Alzheimer type. Annals of neurology. vol 19. issue 3. 1986-04-28. PMID:3963769. |
acetylcholinesterase (ache), the enzyme that degrades acetylcholine, is a heterogeneous enzyme that can be separated into multiple molecular forms. |
1986-04-28 |
2023-08-11 |
human |
| B G Wallac. Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase, and butyrylcholinesterase on cultured myotubes. The Journal of cell biology. vol 102. issue 3. 1986-04-15. PMID:3949878. |
a factor in extracts of the electric organ of torpedo californica causes the formation of clusters of acetylcholine receptors (achrs) and aggregates of acetylcholinesterase (ache) on myotubes in culture. |
1986-04-15 |
2023-08-11 |
Not clear |
| E F Sadykhova, G G Gasanov, V N Ander. Interaction of the cholinergic and catecholaminergic systems of the brain during a change in the motivational behavior of animals. Neuroscience and behavioral physiology. vol 15. issue 6. 1986-03-28. PMID:4094677. |
in connection with the aforementioned, we were interested in studying the activity of acetylcholinesterase (ache) and monoamine oxidase (mao), which participate in the metabolism of acetylcholine and catecholamines, respectively, in the process of a change in the food-motivated behavior of animals in the micro- and ultrastructures of certain hypothalamic nuclei and the cerebral cortex. |
1986-03-28 |
2023-08-11 |
Not clear |
| N Kaneda, Y Noro, T Nagats. Highly sensitive assay for acetylcholinesterase activity by high-performance liquid chromatography with electrochemical detection. Journal of chromatography. vol 344. 1986-03-10. PMID:4086572. |
it is based on the separation of acetylcholine and choline on an octadecylsilane reversed-phase column, followed by their enzymatic conversion into hydrogen peroxide through the post-column reaction with immobilized ache and choline oxidase. |
1986-03-10 |
2023-08-11 |
rat |
| S Brimijoin, K P Mintz, F G Prendergas. An inhibitory monoclonal antibody to rabbit brain acetylcholinesterase. Studies on interaction with the enzyme. Molecular pharmacology. vol 28. issue 6. 1986-01-29. PMID:4079910. |
a recently isolated monoclonal antibody was found to be a potent and powerful inhibitor of the catalytic activity of rabbit brain acetylcholinesterase (ache; acetylcholine acetylhydrolase, ec 3.1.1.7), with an ic50 of about 1 nm and a maximal inhibition of at least 90%. |
1986-01-29 |
2023-08-11 |
rabbit |
| b' I I Krivo\\xc4\\xad, V I Kuleshov, D P Matiushkin, V I Sanotski\\xc4\\xad, T P Se\\xc4\\xa. [Miniature currents of the endplates of the muscle fibers of the diaphragm of the rat after inhibition of acetylcholinesterase with galanthamine]. Neirofiziologiia = Neurophysiology. vol 17. issue 5. 1985-12-26. PMID:2999623.' |
it is supposed that the functional role of synaptic ache in limiting the postsynaptic effect of acetylcholine is not so significant as it is usually considered, therefore it is possible to use the parameters of mepc for the estimation of functional ache activity. |
1985-12-26 |
2023-08-11 |
rat |
| A H Futerman, M G Low, D M Michaelson, I Silma. Solubilization of membrane-bound acetylcholinesterase by a phosphatidylinositol-specific phospholipase C. Journal of neurochemistry. vol 45. issue 5. 1985-11-18. PMID:4045459. |
this selective removal of ache does not affect the amount of acetylcholine released from intact synaptosomes upon k+ depolarization. |
1985-11-18 |
2023-08-11 |
mouse |
| M F Bear, K M Carnes, F F Ebne. Postnatal changes in the distribution of acetylcholinesterase in kitten striate cortex. The Journal of comparative neurology. vol 237. issue 4. 1985-10-31. PMID:3900150. |
the possible contributions of acetylcholine and ache to the postnatal development of kitten striate cortex are discussed. |
1985-10-31 |
2023-08-11 |
cat |
| L Anglister, U J McMaha. Basal lamina directs acetylcholinesterase accumulation at synaptic sites in regenerating muscle. The Journal of cell biology. vol 101. issue 3. 1985-10-09. PMID:3875617. |
at the regenerated neuromuscular junctions, as at the original ones, the muscle fibers are characterized by junctional folds and accumulations of acetylcholine receptors and acetylcholinesterase (ache). |
1985-10-09 |
2023-08-11 |
Not clear |
| J de Belleroche, I M Gardiner, M H Hamilton, N J Birdsal. Analysis of muscarinic receptor concentration and subtypes following lesion of rat substantia innominata. Brain research. vol 340. issue 2. 1985-10-07. PMID:4027649. |
we have examined in rats the effect of lesion of si with kainate (1 microgram/0.5 microliter) on acetylcholine esterase (ache) activity, muscarinic receptor number and subtypes in cerebral cortex at 1, 2 and 4 weeks. |
1985-10-07 |
2023-08-11 |
rat |
| C C Chang, S J Hong, H L Lin, M J S. Acetylcholine hydrolysis during neuromuscular transmission in the synaptic cleft of skeletal muscle of mouse and chick. Neuropharmacology. vol 24. issue 6. 1985-09-24. PMID:2991804. |
on single stimulation, the relative peak concentrations of acetylcholine (ach) at the postsynaptic receptor site of the mouse diaphragm and chick biventer cervicis were estimated to be increased by about 110 and 120% respectively, after complete inhibition of ache. |
1985-09-24 |
2023-08-11 |
mouse |
| D L Kolson, R L Russel. A novel class of acetylcholinesterase, revealed by mutations, in the nematode Caenorhabditis elegans. Journal of neurogenetics. vol 2. issue 2. 1985-09-06. PMID:4020535. |
this residual activity differs markedly from ache classes a and b; its km for acetylcholine is 1000-5000-fold lower, its resistance to eserine is 3000-260,000-fold higher, it is markedly more thermolabile, and it can be separated from classes a and b by ion exchange chromatography. |
1985-09-06 |
2023-08-11 |
rat |
| K Akuzawa, K Wakabayash. A serum-free culture of the neurons in the septal, preoptic, and hypothalamic region. Effects of triiodothyronine and estradiol. Endocrinologia japonica. vol 32. issue 1. 1985-09-04. PMID:4017971. |
effects of triiodothyronine (t3) and estradiol (e2) on the activities of choline acetyltransferase (chat) and acetylcholinesterase (ache), synthetic and degradative enzymes for acetylcholine, respectively, were examined in this culture. |
1985-09-04 |
2023-08-11 |
rat |
| Y Take, S Narumi, E Kurihara, M Shibota, Y Saji, Y Nagaw. [Pharmacological study of the temporary cerebral ischemic rats produced by bilateral vertebral and carotid artery occlusion. Effects of DN-1417]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 85. issue 3. 1985-08-12. PMID:2861149. |
in addition, dn-1417 (10 mg/kg) recovered the various changes such as decrease of 5-hydroxytryptamine (5-ht) levels, increase of cyclic amp (camp) levels, inhibition of [3h]-choline uptake, depression of choline acetyltransferase (cat) and acetylcholine esterase (ache) activities, and shortened the durations of hyperperfusion and hypoperfusion of rcbf. |
1985-08-12 |
2023-08-11 |
rat |