| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B V Manyam, E Giacobini, J A Collive. Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease. Journal of neurology. vol 237. issue 5. 1990-12-04. PMID:2146369. |
the caudate nucleus has the highest acetylcholinesterase (ache) activity in the brain and it has been shown that autopsied brain tissue of patients with huntington's disease (hd) have reduced levels of acetylcholine. |
1990-12-04 |
2023-08-11 |
Not clear |
| G Malinger, H Zakut, H Sore. Cholinoceptive properties of human primordial, preantral, and antral oocytes: in situ hybridization and biochemical evidence for expression of cholinesterase genes. Journal of molecular neuroscience : MN. vol 1. issue 2. 1990-09-27. PMID:2641279. |
functional acetylcholine receptors were electrophysiologically demonstrated in amphibian and mammalian oocyte membranes, and activity of the acetylcholine-hydrolyzing enzyme, acetylcholinesterase (ache), was biochemically measured in the exceptionally big oocytes of the frog xenopus laevis. |
1990-09-27 |
2023-08-11 |
human |
| M Adler, M G Filber. Role of butyrylcholinesterase in canine tracheal smooth muscle function. FEBS letters. vol 267. issue 1. 1990-08-16. PMID:2365076. |
the role of butyrylcholinesterase (buche) and acetylcholinesterase (ache) in in regulating acetylcholine (ach) lifetime was investigated by use of selective cholinesterase (che) inhibitors. |
1990-08-16 |
2023-08-11 |
Not clear |
| M Z Ansari, A Kumar, R L Prasad, A Basu, B N Sahai, A P Sinh. Clinico-biochemical use of serum acetylcholine esterase following treatment with synthetic pyrethroids, cypermethrin and fenvalerate, in cattle and buffalo experimentally infested with Boophilus microplus. Indian journal of experimental biology. vol 28. issue 3. 1990-08-13. PMID:2365420. |
following treatment, cypermethrin and fenvalerate, were found to have inhibitory effect on serum acetylcholine esterase (ache) activity of cattle and buffalo experimentally infested with b. microplus. |
1990-08-13 |
2023-08-11 |
cattle |
| R H Hollands, S M Drance, P H House, M Schulze. Control of intraocular pressure after cataract extraction. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie. vol 25. issue 3. 1990-08-06. PMID:2361193. |
we carried out a prospective randomized study in 172 patients undergoing cataract extraction and lens implantation to compare the effects of pilocarpine gel, 1% acetylcholine chloride and 0.01% carbachol on early postoperative intraocular pressure (iop), to determine the effect of sodium hyaluronate on iop and to compare the effects of 0.01% carbachol (full-strength) and 0.005% carbachol (half-strength) on iop, pupil size and brow ache. |
1990-08-06 |
2023-08-11 |
Not clear |
| J C Szerb, A Fin. Is glutamate a co-transmitter in cortical cholinergic terminals? Effects of nucleus basalis lesion and of presynaptic muscarinic agents. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972643. |
to obtain additional evidence in support of the co-transmitter role of glutamate in cortical cholinergic terminals proposed by docherty et al., the right nucleus basalis in rats was lesioned with ibotenic acid; resulting changes in cortical acetylcholinesterase (ache) staining, glutamate content, and the release of [3h]acetylcholine ([ 3h]ach) and glutamate from cortical slices from the two sides were compared. |
1990-08-01 |
2023-08-11 |
rat |
| E Kumamoto, P Shinnick-Gallaghe. Action of an irreversible acetylcholine esterase inhibitor, soman, on muscarinic hyperpolarization in cat bladder parasympathetic ganglia. British journal of pharmacology. vol 99. issue 1. 1990-06-07. PMID:2331568. |
intracellular recording techniques were used to examine the action of an irreversible acetylcholine esterase (ache) inhibitor, soman, on the hyperpolarizations mediated through muscarinic cholinoceptors in cat bladder parasympathetic neurones. |
1990-06-07 |
2023-08-11 |
cat |
| L A Stephenson, M A Kolk. Acetylcholinesterase inhibitor, pyridostigmine bromide, reduces skin blood flow in humans. The American journal of physiology. vol 258. issue 4 Pt 2. 1990-05-25. PMID:2184685. |
the increased threshold for initiation of cutaneous vasodilation with ache inhibition by pyr is compatible with nonthermal modulation of the control of thermoregulation through increased acetylcholine (ach) accumulation. |
1990-05-25 |
2023-08-11 |
human |
| H S Lotwick, L W Haynes, J Ha. Glycyl-L-glutamine stimulates the accumulation of A12 acetylcholinesterase but not of nicotinic acetylcholine receptors in quail embryonic myotubes by a cyclic AMP-independent mechanism. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2156012. |
myotubes prepared from the japanese quail embryo at 9 days gestation were cultivated in the presence of glycyl-l-glutamine (gly-gln, beta-endorphin c-terminal dipeptide) or glycyl-glutamic acid (gly-glu), and changes in the activity of acetylcholinesterase (ache) molecular forms and binding of 125i-alpha-bungarotoxin (alpha bgt) to cell surface nicotinic acetylcholine receptors were measured. |
1990-04-20 |
2023-08-11 |
Not clear |
| M H Tuszynski, D M Armstrong, F H Gag. Basal forebrain cell loss following fimbria/fornix transection. Brain research. vol 508. issue 2. 1990-04-09. PMID:2306615. |
following fimbria/fornix transection, cells in the medial septum appear to undergo retrograde degeneration as shown by nissl and acetylcholine esterase (ache) staining. |
1990-04-09 |
2023-08-11 |
Not clear |
| J E Sweeney, P S Puttfarcken, J T Coyl. Galanthamine, an acetylcholinesterase inhibitor: a time course of the effects on performance and neurochemical parameters in mice. Pharmacology, biochemistry, and behavior. vol 34. issue 1. 1990-04-03. PMID:2626444. |
the time course of the effects of the long-acting acetylcholinesterase (ache) inhibitor, galanthamine, on a spatial navigation task and on ache and acetylcholine (ach) levels were investigated in mice. |
1990-04-03 |
2023-08-11 |
mouse |
| J C Jay, K F Baral. Denervated single myofibers: neurite interactions and synaptic molecules. Muscle & nerve. vol 12. issue 12. 1990-03-20. PMID:2622472. |
(1) three molecules that are found at the neuromuscular junction (nmj)--acetylcholinesterase (ache), acetylcholine receptors (achrs), and gelasmin (an acetylcholine receptor clustering factor that is found enriched at nmj of adult muscle)--were reduced with increasing periods of denervation but not with aging. |
1990-03-20 |
2023-08-11 |
rat |
| H Soreq, H Zaku. Amplification of butyrylcholinesterase and acetylcholinesterase genes in normal and tumor tissues: putative relationship to organophosphorous poisoning. Pharmaceutical research. vol 7. issue 1. 1990-03-12. PMID:2405380. |
further analysis revealed that both the che and the ache genes, encoding acetylcholinesterase (acetylcholine acetyl hydrolase; ec 3.1.1.7), are amplified in leukemias and platelet disorders and that the tumorigenic expression of these genes in ovarian carcinomas is associated with their frequent coamplification in these tumors. |
1990-03-12 |
2023-08-11 |
Not clear |
| J Kiss, M Schlumpf, R Baláz. Selective retardation of the development of the basal forebrain cholinergic and pontine catecholaminergic nuclei in the brain of trisomy 16 mouse, an animal model of Down's syndrome. Brain research. Developmental brain research. vol 50. issue 2. 1990-03-08. PMID:2575464. |
the distribution of acetylcholine esterase (ache)-, tyrosine hydroxylase (th)- and 5-hydroxytryptamine (5-ht)-positive cells in the trisomic brain was similar to that observed in chromosomally balanced littermates. |
1990-03-08 |
2023-08-11 |
mouse |
| P De Sarno, M Pomponi, E Giacobini, X C Tang, E William. The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat. Neurochemical research. vol 14. issue 10. 1990-02-21. PMID:2608162. |
increases in acetylcholine (ach) levels also show regional differences, however, there is no direct relationship between ache inhibition and ach increase. |
1990-02-21 |
2023-08-11 |
rat |
| C Pfister, R Schade, T Ot. Sexually dimorphic level of CCK-8-like immunoreactive neuronal somata within several basal forebrain nuclei of the rat. Experimental and clinical endocrinology. vol 94. issue 1-2. 1990-01-26. PMID:2599012. |
the comparison of these findings with those of rapid golgi technique and ache histochemistry suggested that all cck-8 immunostaining nerve cells should be aspiny neurons and, partly at least, a coexistence of cck-8 and acetylcholine is assumed. |
1990-01-26 |
2023-08-11 |
rat |
| H Kobayashi, A Yuyama, K Shioya, K Sat. Effects of carbamate, BPMC, on the central cholinergic functions and behavior of mice. Nihon juigaku zasshi. The Japanese journal of veterinary science. vol 51. issue 4. 1990-01-10. PMID:2585933. |
bpmc increased levels of acetylcholine (ach) in the forebrain for up to 6 hr, and decreased acetylcholinesterase (ache) activity for up to 24 hr. |
1990-01-10 |
2023-08-11 |
mouse |
| X C Tang, P De Sarno, K Sugaya, E Giacobin. Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat. Journal of neuroscience research. vol 24. issue 2. 1989-12-28. PMID:2585551. |
the present study represents the first comprehensive investigation of the effect of huperzine a (hup-a), a new cholinesterase inhibitor (chei) isolated from a lycopodium species, upon acetylcholinesterase (ache) activity, acetylcholine (ach) levels and release, and cholinergic receptors in rat brain following acute i.m. |
1989-12-28 |
2023-08-11 |
mouse |
| C S Payne, M Saeed, A D Wolf. Ligand stabilization of cholinesterases. Biochimica et biophysica acta. vol 999. issue 1. 1989-12-19. PMID:2804138. |
stabilization of fetal bovine serum (fbs) acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) (ache) and human butyrylcholinesterase (acylcholine acylhydrolase, ec 3.1.1.8) (buche) by ligands and inhibitors was studied as a function of physical and chemical perturbation. |
1989-12-19 |
2023-08-11 |
human |
| B Iyenga. Modulation of melanocytic activity by acetylcholine. Acta anatomica. vol 136. issue 2. 1989-12-18. PMID:2510448. |
acetylcholine esterase (ache) activity is lowered in vitiliginous skin. |
1989-12-18 |
2023-08-11 |
Not clear |