| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P De Sarno, E Giacobin. Modulation of acetylcholine release by nicotinic receptors in the rat brain. Journal of neuroscience research. vol 22. issue 2. 1989-06-05. PMID:2709442. |
the specific conditions required in this experiment were achieved by a series of short-lasting periods of acetylcholinesterase (ache) inhibition leading to short-lasting increases of acetylcholine (ach). |
1989-06-05 |
2023-08-11 |
rat |
| L Molinengo, M Orsett. Action of diisopropylfluorophosphate and of diacetylmonoxime on acetylcholine levels and on cholinesterase activity in the central nervous system. Archives internationales de pharmacodynamie et de therapie. vol 295. 1989-05-26. PMID:3245732. |
the modification of the acetylcholinesterase (ache) activity and of the acetylcholine (ach) levels caused by diisopropylfluorophosphate (dfp) alone and in association with 300 mg/kg of diacetylmonoxime (dam) have been studied in the olfactory brain, in the cortex and in the medulla-pons of the rat. |
1989-05-26 |
2023-08-11 |
rat |
| P H Marathe, R H Haschke, J T Slattery, J R Zucker, E G Pavli. Acetylcholine receptor density and acetylcholinesterase activity in skeletal muscle of rats following thermal injury. Anesthesiology. vol 70. issue 4. 1989-05-05. PMID:2930003. |
in an effort to identify the mechanism(s) responsible for the resistance to nondepolarizing muscle relaxants, the density of acetylcholine receptors (achr) and the activity of acetylcholinesterase (ache) were determined in rats following a 30% total body surface thermal injury at a time when resistance to atracurium is maximum. |
1989-05-05 |
2023-08-11 |
rat |
| D Casper, P Davie. Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. Brain research. vol 478. issue 1. 1989-04-27. PMID:2924123. |
choline acetyltransferase (acetyl-coa:choline o-acetyltransferase, ec 2.3.1.6, abbreviated chat), the biosynthetic enzyme for acetylcholine and acetylcholinesterase (ec 3.1.1.7, abbreviated ache) are expressed in a human cholinergic neuroblastoma cell line, mc-ixc. |
1989-04-27 |
2023-08-11 |
human |
| T A Laasber. [The cholinergic system in the early development of chickens. 1. Choline acetyltransferase and acetylcholinesterase as the key regulators of acetylcholine metabolism]. Ontogenez. vol 19. issue 6. 1989-04-20. PMID:3231404. |
acetylcholine esterase (ache, ec 3.1.1.7) and choline acetyltransferase (cat, ec 2.3.1.6) activities were studied in the early chick embryos. |
1989-04-20 |
2023-08-11 |
cat |
| D W Schwarz, I E Schwarz, K H. Transmitter neurochemistry of the efferent neuron system innervating the labyrinth. The Journal of otolaryngology. vol 18. issue 1. 1989-04-18. PMID:2564051. |
medial cochlear efferents, terminating under outer hair cells, may also be cholinergic since they stain intensely for acetylcholine esterase (ache) after pre-treatment with the ache inhibitor diisopropylfluorophosphate (dfp). |
1989-04-18 |
2023-08-11 |
rat |
| S Manolov, M Davidof. [Acetylcholinesterase activity, choline acetyltransferase and GABA immunoreactivity in the ventral horn of the spinal cord of rats during chromatolysis]. Revue neurologique. vol 145. issue 1. 1989-04-11. PMID:2646682. |
these results suggest that during chromatolysis: 1. the production of acetylcholine and gaba decreases; 2. the gaba which coexists within some cholinergic motoneurons may be expressed by these cells and 3. the ache activity may also in the future be used as a marker of the cholinergic system of the anterior horn cells of the spinal cord. |
1989-04-11 |
2023-08-11 |
rat |
| A Ouaissi, J Cornette, P Velge, A Capro. Identification of anti-acetylcholinesterase and anti-idiotype antibodies in human and experimental Chagas' disease: pathological implications. European journal of immunology. vol 18. issue 12. 1989-03-14. PMID:3146509. |
this report presents evidence that human acetylcholinesterase (ache; acetylcholine hydrolase, ec3.1.1.7) exhibits immunological cross-reactivity with the protozoan parasite trypanosoma cruzi. |
1989-03-14 |
2023-08-11 |
mouse |
| N Ia Lukomskaia, V Iu Bol'shakov, M V Samoĭlov. [Comparative research on synaptic transmission in the sympathetic ganglia of rabbits and frogs during acetylcholinesterase inhibition]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 24. issue 5. 1989-03-06. PMID:2851243. |
organophosphorus inhibitor of acetylcholinesterase (ache) armin (1 x 10(-6) m) induced a variety of pre- and postsynaptic effects resulting from the ache inhibition and subsequent accumulation of acetylcholine (ach) in the synaptic cleft. |
1989-03-06 |
2023-08-11 |
rabbit |
| W J Wolfgang, M A Fort. Expression of acetylcholinesterase during visual system development in Drosophila. Developmental biology. vol 131. issue 2. 1989-03-03. PMID:2912799. |
as in other insects acetylcholine (ach) and acetylcholinesterase (ache) function in synaptic transmission in the central nervous system of drosophila. |
1989-03-03 |
2023-08-11 |
drosophila_melanogaster |
| W J Wolfgang, M A Fort. Expression of acetylcholinesterase during visual system development in Drosophila. Developmental biology. vol 131. issue 2. 1989-03-03. PMID:2912799. |
studies on flies mutant for ache indicate that in addition to its synaptic function of inactivating acetylcholine, this neural enzyme is required for normal development of the nervous system (j.c. hall, s.n. |
1989-03-03 |
2023-08-11 |
drosophila_melanogaster |
| T Arendt, D Henning, J A Gray, R Marchbank. Loss of neurons in the rat basal forebrain cholinergic projection system after prolonged intake of ethanol. Brain research bulletin. vol 21. issue 4. 1989-02-22. PMID:2850095. |
activity of choline acetyltransferase (chat) and ache in the basal forebrain was simultaneously reduced to 74% and 81% and content of acetylcholine (ach) to 56% of control values respectively. |
1989-02-22 |
2023-08-11 |
rat |
| V E Baburin, L V Suvorov. [Enzymatic activity of neurons of various parts of the digestive tube in postnatal ontogenesis of the rat (cytophotometric histochemical study)]. Arkhiv anatomii, gistologii i embriologii. vol 95. issue 8. 1989-02-14. PMID:3214303. |
glucose-6-phosphatase dehydrogenase, nadph-dehydrogenase, acid phosphatase, alkaline phosphatase (aph), monoamine oxidase, acetylcholine esterase (ache) have been revealed in 19-20-day-old embryos, in 1-, 21-, 30-day-old rats and in mature rats. |
1989-02-14 |
2023-08-11 |
rat |
| A Tokunag. Superior olivary and lateral lemniscal neurons projecting to the cochlea in the guinea pig. Neuroscience research. vol 6. issue 1. 1989-01-25. PMID:2462200. |
a combination of acetylcholine esterase (ache) histochemistry with the tracing of retrograde axonal transport of a fluorescent dye (dapi) revealed that vll neurons projecting to the cochlea, as well as about 85% of lso neurons projecting to the ipsilateral cochlea, were ache-positive. |
1989-01-25 |
2023-08-11 |
Not clear |
| K K Hreib, D L Rosene, M B Mos. Basal forebrain efferents to the medial dorsal thalamic nucleus in the rhesus monkey. The Journal of comparative neurology. vol 277. issue 3. 1989-01-24. PMID:2461974. |
in order to determine the extent of the cholinergic input to mdmc from the bf, one of the hrp cases was processed for the simultaneous visualization of hrp, and acetylcholinesterase (ache), the hydrolytic enzyme for acetylcholine, and a second case was processed for simultaneous visualization of hrp, and choline acetyltransferase (chat), the synthetic enzyme for acetylcholine. |
1989-01-24 |
2023-08-11 |
monkey |
| R Defez, P Brache. Pheochromocytoma PC12 cells influence the differentiation of co-cultured skeletal myotubes. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 4. issue 2. 1988-10-27. PMID:3455581. |
essentially all the tight contacts established between pc12 cells and myotubes were characterized by a receptor cluster and, in some cases, by an aggregate of an acetylcholine esterase (ache), as visualized by immunohistochemistry. |
1988-10-27 |
2023-08-11 |
rat |
| R Quirio. Characterization and autoradiographic distribution of hemicholinium-3 high-affinity choline uptake sites in mammalian brain. Synapse (New York, N.Y.). vol 1. issue 4. 1988-10-20. PMID:3138770. |
this hypothesis is also supported by quantitative autoradiographic data which demonstrate that the discrete distribution of [3h]hc-3 binding sites correlates very well with the known distribution of other cholinergic markers such as choline acetyltransferase (chat), acetylcholinesterase (ache), hacu, and [3h]ah-5183 (blocker of the vesicular transport of acetylcholine). |
1988-10-20 |
2023-08-11 |
rat |
| H Kobayashi, A Yuyama, T Ohkawa, T Kajit. Effect of single or chronic injection with a carbamate, propoxur, on the brain cholinergic system and behavior of mice. Japanese journal of pharmacology. vol 47. issue 1. 1988-10-06. PMID:3411818. |
single injection caused an increase in brain acetylcholine (ach) content at 10 and 60 min; and it caused decreases in acetylcholinesterase (ache) activity at 10, 60 and 180 min, high-affinity choline uptake into synaptosomes at 10 and 60 min, and [3h]quinuclidinyl benzilate (qnb) binding at 10 min without causing any change in choline acetyltransferase (chat) activity. |
1988-10-06 |
2023-08-11 |
mouse |
| T M Turpaev, M N Semenov. Recovery of acetylcholinesterase activity after irreversible inhibition by organophosphorous compounds in embryonic development. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 89. issue 2. 1988-08-12. PMID:2898993. |
it is possible that acetylcholine accumulated as a result of partial ache inhibition is responsible for the compensatory increase in ache biosynthesis. |
1988-08-12 |
2023-08-11 |
chicken |
| S A Greenfield, J J Jack, A T Last, M Frenc. An electrophysiological action of acetylcholinesterase independent of its catalytic site. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:3384044. |
these effects seem to be unrelated to hydrolysis of acetylcholine, but the underlying cellular mechanisms of these actions of ache are unknown. |
1988-07-29 |
2023-08-11 |
Not clear |