| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vahulabaranan Rajagopalan, Swethaa Venkataraman, Devi Sri Rajendran, Vaidyanathan Vinoth Kumar, Vaithyanathan Vasanth Kumar, Gayathri Rangasam. Acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: A literature review. Environmental research. 2023-03-22. PMID:36948285. |
acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: a literature review. |
2023-03-22 |
2023-08-14 |
human |
| Abdussamat Güze. Relationship Between Phenolic Content Determined by LC-MS/MS and Antioxidant Capacity and Enzyme Inhibition of Cyclotrichium Niveum L. Chemistry & biodiversity. 2023-03-09. PMID:36891984. |
the phytochemical composition of the plant, inhibition of acetylcholinesterase (ache) (which hydrolyzes the neurotransmitter acetylcholine), inhibition of paraoxonase for antiatherosclerotic activity (hpon 1) (which detoxifies organophosphates), and antioxidant capacity of this plant. |
2023-03-09 |
2023-08-14 |
Not clear |
| Christina Rabeler, TaiXi Gong, Danielle Ireland, Olivier Cochet-Escartin, Eva-Maria S Collin. Acetylcholinesterase Activity Staining in Freshwater Planarians. Current protocols. vol 3. issue 2. 2023-02-17. PMID:36799654. |
the serine hydrolase acetylcholinesterase (ache) is an important neuronal enzyme which catalyzes the hydrolysis of the neurotransmitter acetylcholine and other choline esters. |
2023-02-17 |
2023-08-14 |
Not clear |
| Aso Hameed Hasan, Sonam Shakya, Faiq H S Hussain, Sankaranarayanan Murugesan, Subhash Chander, Mohammad Rizki Fadhil Pratama, Shajarahtunnur Jamil, Basundhara Das, Subhrajit Biswas, Joazaizulfazli Jamali. Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids. Journal of biomolecular structure & dynamics. 2023-01-02. PMID:36591704. |
the major enzyme responsible for the hydrolytic breakdown of the neurotransmitter acetylcholine (ach) is acetylcholinesterase (ache). |
2023-01-02 |
2023-08-14 |
Not clear |
| Jeremy Neylon, Jarrad N Fuller, Chris van der Poel, Jarrod E Church, Sebastian Dworki. Organophosphate Insecticide Toxicity in Neural Development, Cognition, Behaviour and Degeneration: Insights from Zebrafish. Journal of developmental biology. vol 10. issue 4. 2022-11-22. PMID:36412643. |
organophosphate (op) insecticides are used to eliminate agricultural threats posed by insects, through inhibition of the neurotransmitter acetylcholinesterase (ache). |
2022-11-22 |
2023-08-14 |
zebrafish |
| Xumin Lin, Yixi Zhang, Baojun Yang, Lingchun Zhang, Yunru Chen, Zewen Li. Multiple acetylcholinesterases in Pardosa pseudoannulata brain worked collaboratively to provide protection from organophosphorus insecticides. Ecotoxicology and environmental safety. vol 248. 2022-11-21. PMID:36410143. |
acetylcholinesterase (ache) is an essential neurotransmitter hydrolase in nervous systems of animals and its number varies among species. |
2022-11-21 |
2023-08-14 |
spider |
| Nancy D Asen, Ogadimma D Okagu, Chibuike C Udenigwe, Rotimi E Aluk. Frontiers in nutrition. vol 9. 2022-11-07. PMID:36337665. |
compounds with structural similarities to the neurotransmitter (acetylcholine) are mostly used to inhibit the activity of acetylcholinesterase (ache) in alzheimer's disease (ad) therapy. |
2022-11-07 |
2023-08-14 |
Not clear |
| Manish Kumar, Komalpreet Kaur, Thakur Gurjeet Sing. Neuroprotective Effects of Carbonic Anhydrase Inhibition and Cyclic Adenosine Monophosphate Activation in Mouse Model of Transient Global Cerebral Ischemia and Reperfusion. Neuromolecular medicine. 2022-10-28. PMID:36306034. |
dcpa and/or fsk attenuated tgci/r-induced brain edema, blood-brain barrier dysfunction, oxidative-nitrosative stress, pro-inflammatory cytokines, acetylcholinesterase activity, cell death, and neurotransmitter imbalance (e.g., glutamate, γ-aminobutyric acid). |
2022-10-28 |
2023-08-14 |
mouse |
| Jeyaraj Jeyavani, Ashokkumar Sibiya, Narayanan Gopi, Shahid Mahboob, Khalid A Al-Ghanim, Fahad Al-Misned, Zubair Ahmed, Mian Nadeem Riaz, Balasubramanian Palaniappan, Marimuthu Govindarajan, Baskaralingam Vaseehara. Ingestion and impacts of water-borne polypropylene microplastics on Daphnia similis. Environmental science and pollution research international. 2022-09-22. PMID:36136182. |
additionally, the amount of the neurotransmitter enzyme acetylcholinesterase (ache) activity was decreased. |
2022-09-22 |
2023-08-14 |
cat |
| Muslum Gok, Cigdem Cicek, Suat Sari, Ebru Bodu. Novel activity of human BChE: Lipid hydrolysis. Biochimie. 2022-09-20. PMID:36126749. |
acetylcholinesterase and butyrylcholinesterase (bche) typically hydrolyze the neurotransmitter acetylcholine. |
2022-09-20 |
2023-08-14 |
human |
| Farida Begum, Najeeb Ur Rehman, Ajmal Khan, Sajid Iqbal, Rehan Zafar Paracha, Jalal Uddin, Ahmed Al-Harrasi, Muhammad Arif Lodh. 2-Mercaptobenzimidazole clubbed hydrazone for Alzheimer's therapy: Frontiers in pharmacology. vol 13. 2022-09-05. PMID:36059999. |
it is a multifactorial disease, developed by the breakdown of the neurotransmitter acetylcholine via acetylcholinesterase (ache). |
2022-09-05 |
2023-08-14 |
Not clear |
| Dou Yang, Fasheng Liu, Mengqi Wan, Jieping Liu, Ling Huang, Chao Chen, Xue Li, Li Zhang, Xiaobing Ding, Xinjun Liao, Guanghua Xiong, Huiqiang Lu, Juhua Xiao, Zigang Ca. Pamiparib Induces Neurodevelopmental Defects and Cerebral Haemorrhage in Zebrafish Embryos via Inhibiting Notch Signalling. Molecular neurobiology. 2022-08-18. PMID:35982279. |
in addition, pamiparib exposure leads to downregulation of acetylcholinesterase (ache) and adenosine triphosphate (atpase) activities, and upregulation of oxidative stress which then leads to apoptosis and disrupts the gene expression involved in the neurodevelopment, neurotransmitter pathways and parkinson's disease (pd) like symptoms. |
2022-08-18 |
2023-08-14 |
zebrafish |
| Letícia A Nascimento, Érica C M Nascimento, João B L Martin. In silico study of tacrine and acetylcholine binding profile with human acetylcholinesterase: docking and electronic structure. Journal of molecular modeling. vol 28. issue 9. 2022-08-10. PMID:35947248. |
in this way, we performed a set of theoretical tests of tacrine ligand and acetylcholine neurotransmitter against the human acetylcholinesterase enzyme. |
2022-08-10 |
2023-08-14 |
human |
| Yang Wang, Jie Song, Xuedong Wang, Qiuhui Qian, Huili Wan. Study on the toxic-mechanism of triclosan chronic exposure to zebrafish (Danio rerio) based on gut-brain axis. The Science of the total environment. 2022-06-30. PMID:35772538. |
tcs-chronic exposure affected the development of zebrafish, induced feminization, obesity physical signs and abnormal organ index and caused neurobehavioral abnormalities by inhibiting both neurotransmitter acetylcholinesterase and dopamine activity, promoting brain neuron apoptosis and accelerating diencephalic lesions. |
2022-06-30 |
2023-08-14 |
zebrafish |
| Karina Pereira Luduvico, Luiza Spohr, Mayara Sandrielly Soares de Aguiar, Fernanda Cardoso Teixeira, Natália Pontes Bona, Julia Eisenhardt de Mello, Roselia Maria Spanevello, Francieli Moro Stefanell. LPS-induced impairment of Na Metabolic brain disease. 2022-06-27. PMID:35759073. |
this neurotransmitter is hydrolyzed by acetylcholinesterase (ache), which plays other cellular roles in processes such as inflammation and oxidative stress. |
2022-06-27 |
2023-08-14 |
Not clear |
| Yan-Ling Su, Dong Liu, Yao-Jie Liu, Yang-Lin Ji, Gui-Shan Liu, Ji-Li-Te Wang, Biao Wang, Hao Wan. Phlorizin alleviates cholinergic memory impairment and regulates gut microbiota in d-galactose induced mice. Experimental gerontology. 2022-06-06. PMID:35660419. |
furthermore, a neurotransmitter of acetylcholine (ach) was enhanced, while acetylcholinesterase (ache) activity was inhibited by phlorizin administration. |
2022-06-06 |
2023-08-14 |
mouse |
| Tomasz Tuzimski, Anna Petruczyni. Determination of Anti-Alzheimer's Disease Activity of Selected Plant Ingredients. Molecules (Basel, Switzerland). vol 27. issue 10. 2022-05-28. PMID:35630702. |
one of the most important therapeutic strategies is controlling the level of acetylcholine-a neurotransmitter in cholinergic synapses-by blocking the degradation of acetylcholine using acetylcholinesterase inhibitors such as tacrine, galantamine, donepezil and rivastigmine. |
2022-05-28 |
2023-08-13 |
Not clear |
| Kritika Kumari, Laishram R Sing. Trimethylamine N-oxide might impair cholinergic system by affecting the structural integrity of Acetylcholinesterase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555536. |
acetylcholinesterase (ache) is an important enzyme responsible for the breakdown of neurotransmitter, acetylcholine and therefore plays a crucial role in neuronal plasticity. |
2022-05-13 |
2023-08-13 |
human |
| Wanjun Zhang, Ruiqi Fan, Sunlin Luo, Ying Liu, Yongpeng Jin, Yongchen Li, Mengqin Xiong, Yiqiang Chen, Li Jia, Xiaoyan Yua. Combined effects of chlorpyrifos and cyfluthrin on neurobehavior and neurotransmitter levels in larval zebrafish. Journal of applied toxicology : JAT. 2022-04-26. PMID:35470462. |
to evaluate the risk of combined exposure, we examined the effects of both compounds, separately and together, on motor activity, acetylcholinesterase (ache) activity, and neurotransmitter levels in larval zebrafish. |
2022-04-26 |
2023-08-13 |
zebrafish |
| Shuaizhang Li, Andrew J Li, Jinghua Zhao, Michael F Santillo, Menghang Xi. Acetylcholinesterase Inhibition Assays for High-Throughput Screening. Methods in molecular biology (Clifton, N.J.). vol 2474. 2022-03-16. PMID:35294755. |
acetylcholinesterase (ache) hydrolyzes acetylcholine (ach), a vital neurotransmitter that regulates muscle movement and brain function, including memory, attention, and learning. |
2022-03-16 |
2023-08-13 |
human |