| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Sakurai, B Yang, T Takata, K Yokon. [Exogenous lactate sustains synaptic activity and neuronal viability, but fails to induce long-term potentiation (LTP)]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 37. issue 12. 2001-03-08. PMID:11201184. |
to investigate possible synaptic dysfunction in alzheimer's disease, we examined the effects of exogenous glucose deprivation and replacement of glucose with lactate on the synaptic transmission, synaptic plasticity, and the morphological integrity of hippocampal neurons. |
2001-03-08 |
2023-08-12 |
rat |
| J Zhou, F Zhang, Y Zhan. Corticosterone inhibits generation of long-term potentiation in rat hippocampal slice: involvement of brain-derived neurotrophic factor. Brain research. vol 885. issue 2. 2001-03-01. PMID:11102572. |
in addition, cort treatment significantly reduced both slope and amplitude ratios of the second evoked epsp to the first one when paired-pulse facilitation (ppf) was established at different interpulse intervals from 20 to 40 ms, suggesting that a presynaptic mechanism may be involved in cort-induced hippocampal synaptic plasticity. |
2001-03-01 |
2023-08-12 |
rat |
| S A Masino, T V Dunwiddi. A transient increase in temperature induces persistent potentiation of synaptic transmission in rat hippocampal slices. Neuroscience. vol 101. issue 4. 2001-03-01. PMID:11113339. |
in summary, we propose that transiently increasing brain slice temperature represents a novel way to induce synaptic plasticity in the hippocampus, and may provide a paradigm to elucidate additional cellular mechanisms involved in functional plasticity. |
2001-03-01 |
2023-08-12 |
rat |
| G J Biessels, S Smale, S E Duis, A Kamal, W H Gispe. The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. Journal of the neurological sciences. vol 182. issue 2. 2001-03-01. PMID:11137514. |
also, long-term potentiation, a form of synaptic plasticity used as a model for learning and memory at the cellular level, was examined in hippocampal slices. |
2001-03-01 |
2023-08-12 |
rat |
| A Rotenberg, T Abel, R D Hawkins, E R Kandel, R U Mulle. Parallel instabilities of long-term potentiation, place cells, and learning caused by decreased protein kinase A activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050131. |
to further elucidate the links among synaptic plasticity, hippocampal place cells, and spatial memory, place cells were recorded from wild-type mice and transgenic "r(ab)" mice with reduced forebrain protein kinase a (pka) activity after introduction into a novel environment. |
2001-02-22 |
2023-08-12 |
mouse |
| A Rotenberg, T Abel, R D Hawkins, E R Kandel, R U Mulle. Parallel instabilities of long-term potentiation, place cells, and learning caused by decreased protein kinase A activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050131. |
the similar time courses of synaptic, network, and behavioral instability suggest that the genetic reduction of pka activity is responsible for the defects at each level and support the idea that hippocampal synaptic plasticity is important in spatial memory. |
2001-02-22 |
2023-08-12 |
mouse |
| Z Sarnyai, E L Sibille, C Pavlides, R J Fenster, B S McEwen, M Tot. Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 26. 2001-02-15. PMID:11121072. |
to test whether a deficit in 5-ht(1a) receptors impairs hippocampus-related functions, we studied hippocampal-dependent learning and memory, synaptic plasticity in the hippocampus, and limbic neuronal excitability in 5-ht(1a)-knockout (ko) mice. |
2001-02-15 |
2023-08-12 |
mouse |
| G Z Huang, H Ujihara, S Takahashi, H Kaba, T Yagi, S Inou. Involvement of complexin II in synaptic plasticity in the CA1 region of the hippocampus: the use of complexin II-lacking mice. Japanese journal of pharmacology. vol 84. issue 2. 2001-02-15. PMID:11128041. |
involvement of complexin ii in synaptic plasticity in the ca1 region of the hippocampus: the use of complexin ii-lacking mice. |
2001-02-15 |
2023-08-12 |
mouse |
| R R Gupta, S Sen, L L Diepenhorst, C N Rudick, S Mare. Estrogen modulates sexually dimorphic contextual fear conditioning and hippocampal long-term potentiation (LTP) in rats(1). Brain research. vol 888. issue 2. 2001-02-15. PMID:11150498. |
the present study examined the role of ovarian steroids in contextual fear conditioning and hippocampal synaptic plasticity in female rats. |
2001-02-15 |
2023-08-12 |
rat |
| C Chen, J C Magee, V Marcheselli, M Hardy, N G Baza. Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. Journal of neurophysiology. vol 85. issue 1. 2001-02-15. PMID:11152738. |
to further investigate the role of paf in synaptic plasticity, we compared ltp in dentate granule cells from hippocampal slices of adult mice deficient in the paf-r and their age-matched wild-type littermates. |
2001-02-15 |
2023-08-12 |
mouse |
| C Chen, J C Magee, V Marcheselli, M Hardy, N G Baza. Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. Journal of neurophysiology. vol 85. issue 1. 2001-02-15. PMID:11152738. |
these data provide evidence that paf-r-deficient mice are a useful model to study ltp in the dentate gyrus and support the notion that paf actively participates in hippocampal synaptic plasticity. |
2001-02-15 |
2023-08-12 |
mouse |
| I Silki. The cortico-basal ganglia-thalamocortical circuit with synaptic plasticity. I. Modification rules for excitatory and inhibitory synapses in the striatum. Bio Systems. vol 57. issue 3. 2001-02-02. PMID:11084240. |
it is pointed out that ca(2+)-dependent modification rules for nmda-dependent (nmda-independent) synaptic plasticity in the striatum are similar to those in the neocortex and hippocampus (cerebellum). |
2001-02-02 |
2023-08-12 |
Not clear |
| Y Isomura, N Kat. Possible regulatory role of dendritic spikes in induction of long-term potentiation at hippocampal schaffer collateral-CA1 synapses. Brain research. vol 883. issue 1. 2001-02-01. PMID:11063994. |
these findings suggest that the activity-dependent attenuation of baps, propagating along the apical dendrite, may serve to regulate hippocampal synaptic plasticity. |
2001-02-01 |
2023-08-12 |
Not clear |
| C Leranth, M Shanabrough, T L Horvat. Hormonal regulation of hippocampal spine synapse density involves subcortical mediation. Neuroscience. vol 101. issue 2. 2001-02-01. PMID:11074158. |
this study explored whether afferent connections of the hippocampus that come from estrogen-sensitive subcortical structures, including the septal complex, median raphe and supramammillary area, play a role in this estrogen-induced hippocampal synaptic plasticity. |
2001-02-01 |
2023-08-12 |
rat |
| P V Nguyen, S N Duffy, J Z Youn. Differential maintenance and frequency-dependent tuning of LTP at hippocampal synapses of specific strains of inbred mice. Journal of neurophysiology. vol 84. issue 5. 2001-01-04. PMID:11067991. |
transgenic and knockout mice are used extensively to elucidate the molecular mechanisms of hippocampal synaptic plasticity. |
2001-01-04 |
2023-08-12 |
mouse |
| S Fujita, Y Ikegaya, N Nishiyama, N Matsuk. Ca2+-independent phospholipase A2 inhibitor impairs spatial memory of mice. Japanese journal of pharmacology. vol 83. issue 3. 2000-12-22. PMID:10952080. |
pharmacological blockade of ca2+-independent phospholipase a2 (pla2) is reported to disintegrate hippocampal synaptic plasticity, which is thought to be the cellular mechanism underlying learning and memory. |
2000-12-22 |
2023-08-12 |
mouse |
| S M O'Mara, S Commins, M Anderso. Synaptic plasticity in the hippocampal area CA1-subiculum projection: implications for theories of memory. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985284. |
synaptic plasticity in the hippocampal area ca1-subiculum projection: implications for theories of memory. |
2000-12-22 |
2023-08-12 |
Not clear |
| S M O'Mara, S Commins, M Anderso. Synaptic plasticity in the hippocampal area CA1-subiculum projection: implications for theories of memory. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985284. |
this paper reviews investigations of synaptic plasticity in the major, and underexplored, pathway from hippocampal area ca1 to the subiculum. |
2000-12-22 |
2023-08-12 |
Not clear |
| M U Naik, E Benedikz, I Hernandez, J Libien, J Hrabe, M Valsamis, D Dow-Edwards, M Osman, T C Sackto. Distribution of protein kinase Mzeta and the complete protein kinase C isoform family in rat brain. The Journal of comparative neurology. vol 426. issue 2. 2000-12-14. PMID:10982466. |
our previous studies have shown that many of these pkcs participate in synaptic plasticity in the ca1 region of the hippocampus. |
2000-12-14 |
2023-08-12 |
rat |
| V Y Bolshakov, L Carboni, M H Cobb, S A Siegelbaum, F Belardett. Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nature neuroscience. vol 3. issue 11. 2000-12-11. PMID:11036267. |
although the function of the p42/p44 mitogen-activated protein (map) kinase pathway in long-term potentiation at hippocampal ca3-ca1 synapses has been well described, relatively little is known about the importance of the p38 map kinase pathway in synaptic plasticity. |
2000-12-11 |
2023-08-12 |
Not clear |