| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Zhu, R J Hamm, T M Reeves, J T Povlishock, L L Phillip. Postinjury administration of L-deprenyl improves cognitive function and enhances neuroplasticity after traumatic brain injury. Experimental neurology. vol 166. issue 1. 2000-12-07. PMID:11031090. |
these results suggest that dopaminergic/noradrenergic enhancement facilitates cognitive recovery after brain injury and that noradrenergic fiber integrity is correlated with enhanced synaptic plasticity in the injured hippocampus. |
2000-12-07 |
2023-08-12 |
human |
| R Fabian-Fine, W Volknandt, A Fine, M G Stewar. Age-dependent pre- and postsynaptic distribution of AMPA receptors at synapses in CA3 stratum radiatum of hippocampal slice cultures compared with intact brain. The European journal of neuroscience. vol 12. issue 10. 2000-11-30. PMID:11029638. |
organotypic slice cultures of rat hippocampus are widely used as experimental preparations for the study of synaptic plasticity, but their degree of correspondence with intact brain is not fully known. |
2000-11-30 |
2023-08-12 |
rat |
| W H Gispen, G J Biessel. Cognition and synaptic plasticity in diabetes mellitus. Trends in neurosciences. vol 23. issue 11. 2000-11-30. PMID:11074263. |
in animal models of diabetes, impairments of spatial learning occur in association with distinct changes in hippocampal synaptic plasticity. |
2000-11-30 |
2023-08-12 |
Not clear |
| S Fujii, M Matsumoto, K Igarashi, H Kato, K Mikoshib. Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040263. |
to evaluate the role of the type 1 inositol-1,4,5-trisphosphate receptor (ip3r1) in hippocampal synaptic plasticity, we studied ltp, ltd, dp, and ltp suppression of the field excitatory postsynaptic potentials (epsps) in the ca1 neurons of mice lacking the ip3r1. |
2000-11-21 |
2023-08-12 |
mouse |
| F M Kuenzi, S M Fitzjohn, R A Morton, G L Collingridge, G R Seabroo. Reduced long-term potentiation in hippocampal slices prepared using sucrose-based artificial cerebrospinal fluid. Journal of neuroscience methods. vol 100. issue 1-2. 2000-11-21. PMID:11040373. |
this study compared the effect of preparing brain slices using chilled sucrose-based acsf versus the conventional method using chilled acsf on hippocampal synaptic plasticity. |
2000-11-21 |
2023-08-12 |
Not clear |
| C M Coussens, J M Williams, D R Ireland, W C Abraha. Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974310. |
tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. |
2000-11-13 |
2023-08-12 |
rat |
| C M Coussens, J M Williams, D R Ireland, W C Abraha. Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974310. |
we examined the effects of two protein tyrosine phosphatase inhibitors on the induction of synaptic plasticity in ca1 slices of rat hippocampus. |
2000-11-13 |
2023-08-12 |
rat |
| S Davis, H Salin, A Helme-Guizon, S Dumas, A Stéphan, M Corbex, J Mallet, S Laroch. Dysfunctional regulation of alphaCaMKII and syntaxin 1B transcription after induction of LTP in the aged rat. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998111. |
these results suggest that molecular mechanisms implicated in two aspects of hippocampal synaptic plasticity malfunction during normal ageing and therefore may have some contributory role in the decline in memory function routinely observed in ageing. |
2000-11-07 |
2023-08-12 |
rat |
| A K Saghatelyan, S Gorissen, M Albert, B Hertlein, M Schachner, A Dityate. The extracellular matrix molecule tenascin-R and its HNK-1 carbohydrate modulate perisomatic inhibition and long-term potentiation in the CA1 region of the hippocampus. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998116. |
these results provide first evidence that tenascin-r and its associated hnk-1 carbohydrate modulate perisomatic inhibition and synaptic plasticity in the hippocampus. |
2000-11-07 |
2023-08-12 |
mouse |
| H Karst, Y J Karten, H M Reichardt, E R de Kloet, G Schütz, M Joël. Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers. Nature neuroscience. vol 3. issue 10. 2000-10-20. PMID:11017168. |
in the brain, these stress hormones potently modulate ionic currents, monoaminergic transmission, synaptic plasticity and cellular viability, most notably in the hippocampus where corticosteroid receptors are highly enriched. |
2000-10-20 |
2023-08-12 |
Not clear |
| C A Barnes, J Meltzer, F Houston, G Orr, K McGann, G L Wen. Chronic treatment of old rats with donepezil or galantamine: effects on memory, hippocampal plasticity and nicotinic receptors. Neuroscience. vol 99. issue 1. 2000-10-18. PMID:10924948. |
because of the well-known age-related changes in spatial memory and hippocampal synaptic plasticity, spatial working memory in the radial eight-arm maze and hippocampal long-term potentiation induction and decay, as well as nicotinic receptor density and affinity, were measured in old rats implanted with minipumps that delivered donepezil, galantamine or saline. |
2000-10-18 |
2023-08-12 |
human |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995855. |
here we have for the first time analyzed different forms of synaptic plasticity in human hippocampus. |
2000-10-18 |
2023-08-12 |
human |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995855. |
because patients with a hippocampal seizure focus showed a marked reduction in verbal memory performance in previous studies, we asked whether synaptic plasticity is similarly affected by the presence of a hippocampal primary seizure focus. |
2000-10-18 |
2023-08-12 |
human |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995855. |
in summary, we show that activity-dependent synaptic plasticity with properties similar to the rodent is available for information storage in the human hippocampus. |
2000-10-18 |
2023-08-12 |
human |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995855. |
because both verbal memory processes and synaptic plasticity are impaired by a hippocampal seizure focus, we suggest that impaired synaptic plasticity may contribute to deficient declarative memory in human temporal lobe epilepsy. |
2000-10-18 |
2023-08-12 |
human |
| M E Gilbert, W R Mundy, K M Crofto. Spatial learning and long-term potentiation in the dentate gyrus of the hippocampus in animals developmentally exposed to Aroclor 1254. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 1. 2000-10-13. PMID:10966516. |
the present study sought to examine hippocampal synaptic plasticity in the dentate gyrus and spatial learning in animals exposed to pcbs early in development. |
2000-10-13 |
2023-08-12 |
rat |
| I E Kudriashov, I V Kudriashov. [Effect of deafferentation of the forelimb on the postnatal development of the synaptic plasticity in the hippocampus]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 50. issue 3. 2000-09-25. PMID:10923389. |
[effect of deafferentation of the forelimb on the postnatal development of the synaptic plasticity in the hippocampus]. |
2000-09-25 |
2023-08-12 |
rat |
| R X Petrie, I C Reid, C A Stewar. The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder. A critical review. Pharmacology & therapeutics. vol 87. issue 1. 2000-09-22. PMID:10924739. |
"depressogenic" stressors in animals and chronic administration of antidepressant agents perturb nmda-dependent synaptic plasticity in the hippocampus. |
2000-09-22 |
2023-08-12 |
Not clear |
| L Velísek, P K Stanton, S L Moshé, I Vath. Prenatal morphine exposure enhances seizure susceptibility but suppresses long-term potentiation in the limbic system of adult male rats. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865073. |
the present study examined the effects of prenatal morphine exposure on nmda-dependent seizure susceptibility in the entorhinal cortex (ec), and on activity-dependent synaptic plasticity at schaffer collateral and perforant path synapses in the hippocampus. |
2000-08-25 |
2023-08-12 |
rat |
| G W Arbuthnott, C A Ingham, J R Wicken. Dopamine and synaptic plasticity in the neostriatum. Journal of anatomy. vol 196 ( Pt 4). 2000-08-22. PMID:10923989. |
using stimulation protocols derived from the experiments on hippocampal synaptic plasticity we have shown that the usual consequence of trains of high frequency stimulation of the cortex is the depression of the size of epsps in the striatal cell. |
2000-08-22 |
2023-08-12 |
rat |