| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Sarnyai, E L Sibille, C Pavlides, R J Fenster, B S McEwen, M Tot. Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 26. 2001-02-15. PMID:11121072. |
to test whether a deficit in 5-ht(1a) receptors impairs hippocampus-related functions, we studied hippocampal-dependent learning and memory, synaptic plasticity in the hippocampus, and limbic neuronal excitability in 5-ht(1a)-knockout (ko) mice. |
2001-02-15 |
2023-08-12 |
mouse |
| G Z Huang, H Ujihara, S Takahashi, H Kaba, T Yagi, S Inou. Involvement of complexin II in synaptic plasticity in the CA1 region of the hippocampus: the use of complexin II-lacking mice. Japanese journal of pharmacology. vol 84. issue 2. 2001-02-15. PMID:11128041. |
involvement of complexin ii in synaptic plasticity in the ca1 region of the hippocampus: the use of complexin ii-lacking mice. |
2001-02-15 |
2023-08-12 |
mouse |
| R R Gupta, S Sen, L L Diepenhorst, C N Rudick, S Mare. Estrogen modulates sexually dimorphic contextual fear conditioning and hippocampal long-term potentiation (LTP) in rats(1). Brain research. vol 888. issue 2. 2001-02-15. PMID:11150498. |
the present study examined the role of ovarian steroids in contextual fear conditioning and hippocampal synaptic plasticity in female rats. |
2001-02-15 |
2023-08-12 |
rat |
| C Chen, J C Magee, V Marcheselli, M Hardy, N G Baza. Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. Journal of neurophysiology. vol 85. issue 1. 2001-02-15. PMID:11152738. |
to further investigate the role of paf in synaptic plasticity, we compared ltp in dentate granule cells from hippocampal slices of adult mice deficient in the paf-r and their age-matched wild-type littermates. |
2001-02-15 |
2023-08-12 |
mouse |
| C Chen, J C Magee, V Marcheselli, M Hardy, N G Baza. Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. Journal of neurophysiology. vol 85. issue 1. 2001-02-15. PMID:11152738. |
these data provide evidence that paf-r-deficient mice are a useful model to study ltp in the dentate gyrus and support the notion that paf actively participates in hippocampal synaptic plasticity. |
2001-02-15 |
2023-08-12 |
mouse |
| I Silki. The cortico-basal ganglia-thalamocortical circuit with synaptic plasticity. I. Modification rules for excitatory and inhibitory synapses in the striatum. Bio Systems. vol 57. issue 3. 2001-02-02. PMID:11084240. |
it is pointed out that ca(2+)-dependent modification rules for nmda-dependent (nmda-independent) synaptic plasticity in the striatum are similar to those in the neocortex and hippocampus (cerebellum). |
2001-02-02 |
2023-08-12 |
Not clear |
| Y Isomura, N Kat. Possible regulatory role of dendritic spikes in induction of long-term potentiation at hippocampal schaffer collateral-CA1 synapses. Brain research. vol 883. issue 1. 2001-02-01. PMID:11063994. |
these findings suggest that the activity-dependent attenuation of baps, propagating along the apical dendrite, may serve to regulate hippocampal synaptic plasticity. |
2001-02-01 |
2023-08-12 |
Not clear |
| C Leranth, M Shanabrough, T L Horvat. Hormonal regulation of hippocampal spine synapse density involves subcortical mediation. Neuroscience. vol 101. issue 2. 2001-02-01. PMID:11074158. |
this study explored whether afferent connections of the hippocampus that come from estrogen-sensitive subcortical structures, including the septal complex, median raphe and supramammillary area, play a role in this estrogen-induced hippocampal synaptic plasticity. |
2001-02-01 |
2023-08-12 |
rat |
| P V Nguyen, S N Duffy, J Z Youn. Differential maintenance and frequency-dependent tuning of LTP at hippocampal synapses of specific strains of inbred mice. Journal of neurophysiology. vol 84. issue 5. 2001-01-04. PMID:11067991. |
transgenic and knockout mice are used extensively to elucidate the molecular mechanisms of hippocampal synaptic plasticity. |
2001-01-04 |
2023-08-12 |
mouse |
| S Fujita, Y Ikegaya, N Nishiyama, N Matsuk. Ca2+-independent phospholipase A2 inhibitor impairs spatial memory of mice. Japanese journal of pharmacology. vol 83. issue 3. 2000-12-22. PMID:10952080. |
pharmacological blockade of ca2+-independent phospholipase a2 (pla2) is reported to disintegrate hippocampal synaptic plasticity, which is thought to be the cellular mechanism underlying learning and memory. |
2000-12-22 |
2023-08-12 |
mouse |
| S M O'Mara, S Commins, M Anderso. Synaptic plasticity in the hippocampal area CA1-subiculum projection: implications for theories of memory. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985284. |
synaptic plasticity in the hippocampal area ca1-subiculum projection: implications for theories of memory. |
2000-12-22 |
2023-08-12 |
Not clear |
| S M O'Mara, S Commins, M Anderso. Synaptic plasticity in the hippocampal area CA1-subiculum projection: implications for theories of memory. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985284. |
this paper reviews investigations of synaptic plasticity in the major, and underexplored, pathway from hippocampal area ca1 to the subiculum. |
2000-12-22 |
2023-08-12 |
Not clear |
| M U Naik, E Benedikz, I Hernandez, J Libien, J Hrabe, M Valsamis, D Dow-Edwards, M Osman, T C Sackto. Distribution of protein kinase Mzeta and the complete protein kinase C isoform family in rat brain. The Journal of comparative neurology. vol 426. issue 2. 2000-12-14. PMID:10982466. |
our previous studies have shown that many of these pkcs participate in synaptic plasticity in the ca1 region of the hippocampus. |
2000-12-14 |
2023-08-12 |
rat |
| V Y Bolshakov, L Carboni, M H Cobb, S A Siegelbaum, F Belardett. Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nature neuroscience. vol 3. issue 11. 2000-12-11. PMID:11036267. |
although the function of the p42/p44 mitogen-activated protein (map) kinase pathway in long-term potentiation at hippocampal ca3-ca1 synapses has been well described, relatively little is known about the importance of the p38 map kinase pathway in synaptic plasticity. |
2000-12-11 |
2023-08-12 |
Not clear |
| J Zhu, R J Hamm, T M Reeves, J T Povlishock, L L Phillip. Postinjury administration of L-deprenyl improves cognitive function and enhances neuroplasticity after traumatic brain injury. Experimental neurology. vol 166. issue 1. 2000-12-07. PMID:11031090. |
these results suggest that dopaminergic/noradrenergic enhancement facilitates cognitive recovery after brain injury and that noradrenergic fiber integrity is correlated with enhanced synaptic plasticity in the injured hippocampus. |
2000-12-07 |
2023-08-12 |
human |
| R Fabian-Fine, W Volknandt, A Fine, M G Stewar. Age-dependent pre- and postsynaptic distribution of AMPA receptors at synapses in CA3 stratum radiatum of hippocampal slice cultures compared with intact brain. The European journal of neuroscience. vol 12. issue 10. 2000-11-30. PMID:11029638. |
organotypic slice cultures of rat hippocampus are widely used as experimental preparations for the study of synaptic plasticity, but their degree of correspondence with intact brain is not fully known. |
2000-11-30 |
2023-08-12 |
rat |
| W H Gispen, G J Biessel. Cognition and synaptic plasticity in diabetes mellitus. Trends in neurosciences. vol 23. issue 11. 2000-11-30. PMID:11074263. |
in animal models of diabetes, impairments of spatial learning occur in association with distinct changes in hippocampal synaptic plasticity. |
2000-11-30 |
2023-08-12 |
Not clear |
| S Fujii, M Matsumoto, K Igarashi, H Kato, K Mikoshib. Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040263. |
to evaluate the role of the type 1 inositol-1,4,5-trisphosphate receptor (ip3r1) in hippocampal synaptic plasticity, we studied ltp, ltd, dp, and ltp suppression of the field excitatory postsynaptic potentials (epsps) in the ca1 neurons of mice lacking the ip3r1. |
2000-11-21 |
2023-08-12 |
mouse |
| F M Kuenzi, S M Fitzjohn, R A Morton, G L Collingridge, G R Seabroo. Reduced long-term potentiation in hippocampal slices prepared using sucrose-based artificial cerebrospinal fluid. Journal of neuroscience methods. vol 100. issue 1-2. 2000-11-21. PMID:11040373. |
this study compared the effect of preparing brain slices using chilled sucrose-based acsf versus the conventional method using chilled acsf on hippocampal synaptic plasticity. |
2000-11-21 |
2023-08-12 |
Not clear |
| C M Coussens, J M Williams, D R Ireland, W C Abraha. Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974310. |
tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. |
2000-11-13 |
2023-08-12 |
rat |