| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Leranth, M Shanabrough, T L Horvat. Hormonal regulation of hippocampal spine synapse density involves subcortical mediation. Neuroscience. vol 101. issue 2. 2001-02-01. PMID:11074158. |
this study explored whether afferent connections of the hippocampus that come from estrogen-sensitive subcortical structures, including the septal complex, median raphe and supramammillary area, play a role in this estrogen-induced hippocampal synaptic plasticity. |
2001-02-01 |
2023-08-12 |
rat |
| P V Nguyen, S N Duffy, J Z Youn. Differential maintenance and frequency-dependent tuning of LTP at hippocampal synapses of specific strains of inbred mice. Journal of neurophysiology. vol 84. issue 5. 2001-01-04. PMID:11067991. |
transgenic and knockout mice are used extensively to elucidate the molecular mechanisms of hippocampal synaptic plasticity. |
2001-01-04 |
2023-08-12 |
mouse |
| S Fujita, Y Ikegaya, N Nishiyama, N Matsuk. Ca2+-independent phospholipase A2 inhibitor impairs spatial memory of mice. Japanese journal of pharmacology. vol 83. issue 3. 2000-12-22. PMID:10952080. |
pharmacological blockade of ca2+-independent phospholipase a2 (pla2) is reported to disintegrate hippocampal synaptic plasticity, which is thought to be the cellular mechanism underlying learning and memory. |
2000-12-22 |
2023-08-12 |
mouse |
| S M O'Mara, S Commins, M Anderso. Synaptic plasticity in the hippocampal area CA1-subiculum projection: implications for theories of memory. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985284. |
synaptic plasticity in the hippocampal area ca1-subiculum projection: implications for theories of memory. |
2000-12-22 |
2023-08-12 |
Not clear |
| S M O'Mara, S Commins, M Anderso. Synaptic plasticity in the hippocampal area CA1-subiculum projection: implications for theories of memory. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985284. |
this paper reviews investigations of synaptic plasticity in the major, and underexplored, pathway from hippocampal area ca1 to the subiculum. |
2000-12-22 |
2023-08-12 |
Not clear |
| M U Naik, E Benedikz, I Hernandez, J Libien, J Hrabe, M Valsamis, D Dow-Edwards, M Osman, T C Sackto. Distribution of protein kinase Mzeta and the complete protein kinase C isoform family in rat brain. The Journal of comparative neurology. vol 426. issue 2. 2000-12-14. PMID:10982466. |
our previous studies have shown that many of these pkcs participate in synaptic plasticity in the ca1 region of the hippocampus. |
2000-12-14 |
2023-08-12 |
rat |
| V Y Bolshakov, L Carboni, M H Cobb, S A Siegelbaum, F Belardett. Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nature neuroscience. vol 3. issue 11. 2000-12-11. PMID:11036267. |
although the function of the p42/p44 mitogen-activated protein (map) kinase pathway in long-term potentiation at hippocampal ca3-ca1 synapses has been well described, relatively little is known about the importance of the p38 map kinase pathway in synaptic plasticity. |
2000-12-11 |
2023-08-12 |
Not clear |
| J Zhu, R J Hamm, T M Reeves, J T Povlishock, L L Phillip. Postinjury administration of L-deprenyl improves cognitive function and enhances neuroplasticity after traumatic brain injury. Experimental neurology. vol 166. issue 1. 2000-12-07. PMID:11031090. |
these results suggest that dopaminergic/noradrenergic enhancement facilitates cognitive recovery after brain injury and that noradrenergic fiber integrity is correlated with enhanced synaptic plasticity in the injured hippocampus. |
2000-12-07 |
2023-08-12 |
human |
| R Fabian-Fine, W Volknandt, A Fine, M G Stewar. Age-dependent pre- and postsynaptic distribution of AMPA receptors at synapses in CA3 stratum radiatum of hippocampal slice cultures compared with intact brain. The European journal of neuroscience. vol 12. issue 10. 2000-11-30. PMID:11029638. |
organotypic slice cultures of rat hippocampus are widely used as experimental preparations for the study of synaptic plasticity, but their degree of correspondence with intact brain is not fully known. |
2000-11-30 |
2023-08-12 |
rat |
| W H Gispen, G J Biessel. Cognition and synaptic plasticity in diabetes mellitus. Trends in neurosciences. vol 23. issue 11. 2000-11-30. PMID:11074263. |
in animal models of diabetes, impairments of spatial learning occur in association with distinct changes in hippocampal synaptic plasticity. |
2000-11-30 |
2023-08-12 |
Not clear |
| S Fujii, M Matsumoto, K Igarashi, H Kato, K Mikoshib. Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040263. |
to evaluate the role of the type 1 inositol-1,4,5-trisphosphate receptor (ip3r1) in hippocampal synaptic plasticity, we studied ltp, ltd, dp, and ltp suppression of the field excitatory postsynaptic potentials (epsps) in the ca1 neurons of mice lacking the ip3r1. |
2000-11-21 |
2023-08-12 |
mouse |
| F M Kuenzi, S M Fitzjohn, R A Morton, G L Collingridge, G R Seabroo. Reduced long-term potentiation in hippocampal slices prepared using sucrose-based artificial cerebrospinal fluid. Journal of neuroscience methods. vol 100. issue 1-2. 2000-11-21. PMID:11040373. |
this study compared the effect of preparing brain slices using chilled sucrose-based acsf versus the conventional method using chilled acsf on hippocampal synaptic plasticity. |
2000-11-21 |
2023-08-12 |
Not clear |
| C M Coussens, J M Williams, D R Ireland, W C Abraha. Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974310. |
tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. |
2000-11-13 |
2023-08-12 |
rat |
| C M Coussens, J M Williams, D R Ireland, W C Abraha. Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974310. |
we examined the effects of two protein tyrosine phosphatase inhibitors on the induction of synaptic plasticity in ca1 slices of rat hippocampus. |
2000-11-13 |
2023-08-12 |
rat |
| S Davis, H Salin, A Helme-Guizon, S Dumas, A Stéphan, M Corbex, J Mallet, S Laroch. Dysfunctional regulation of alphaCaMKII and syntaxin 1B transcription after induction of LTP in the aged rat. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998111. |
these results suggest that molecular mechanisms implicated in two aspects of hippocampal synaptic plasticity malfunction during normal ageing and therefore may have some contributory role in the decline in memory function routinely observed in ageing. |
2000-11-07 |
2023-08-12 |
rat |
| A K Saghatelyan, S Gorissen, M Albert, B Hertlein, M Schachner, A Dityate. The extracellular matrix molecule tenascin-R and its HNK-1 carbohydrate modulate perisomatic inhibition and long-term potentiation in the CA1 region of the hippocampus. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998116. |
these results provide first evidence that tenascin-r and its associated hnk-1 carbohydrate modulate perisomatic inhibition and synaptic plasticity in the hippocampus. |
2000-11-07 |
2023-08-12 |
mouse |
| H Karst, Y J Karten, H M Reichardt, E R de Kloet, G Schütz, M Joël. Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers. Nature neuroscience. vol 3. issue 10. 2000-10-20. PMID:11017168. |
in the brain, these stress hormones potently modulate ionic currents, monoaminergic transmission, synaptic plasticity and cellular viability, most notably in the hippocampus where corticosteroid receptors are highly enriched. |
2000-10-20 |
2023-08-12 |
Not clear |
| C A Barnes, J Meltzer, F Houston, G Orr, K McGann, G L Wen. Chronic treatment of old rats with donepezil or galantamine: effects on memory, hippocampal plasticity and nicotinic receptors. Neuroscience. vol 99. issue 1. 2000-10-18. PMID:10924948. |
because of the well-known age-related changes in spatial memory and hippocampal synaptic plasticity, spatial working memory in the radial eight-arm maze and hippocampal long-term potentiation induction and decay, as well as nicotinic receptor density and affinity, were measured in old rats implanted with minipumps that delivered donepezil, galantamine or saline. |
2000-10-18 |
2023-08-12 |
human |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995855. |
here we have for the first time analyzed different forms of synaptic plasticity in human hippocampus. |
2000-10-18 |
2023-08-12 |
human |
| H Beck, I V Goussakov, A Lie, C Helmstaedter, C E Elge. Synaptic plasticity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995855. |
because patients with a hippocampal seizure focus showed a marked reduction in verbal memory performance in previous studies, we asked whether synaptic plasticity is similarly affected by the presence of a hippocampal primary seizure focus. |
2000-10-18 |
2023-08-12 |
human |