| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Smriga, H Sait. Effect of selected thallophytic glucans on learning behaviour and short-term potentiation. Phytotherapy research : PTR. vol 14. issue 3. 2000-06-30. PMID:10815005. |
in parallel with the already described enhancement of hippocampal synaptic plasticity by disaccharides, polysaccharides isolated from lichens flavoparmelia caperata and cetrariella islandica, enhanced hippocampal plasticity and behavioural performance in rats. |
2000-06-30 |
2023-08-12 |
rat |
| A Sík, A Gulácsi, Y Lai, W K Doyle, S Pacia, I Mody, T F Freun. Localization of the A kinase anchoring protein AKAP79 in the human hippocampus. The European journal of neuroscience. vol 12. issue 4. 2000-06-21. PMID:10762347. |
we conclude that the spatial selectivity for the action of certain kinases and phosphatases regulating various ligand- and voltage-gated channels may be ensured by the selective presence of their anchoring protein, akap79, at the majority of glutamatergic synapses in the ca1, but not in the ca2/ca3 regions, suggesting profound differences in signal transduction and long-term synaptic plasticity between these regions of the human hippocampus. |
2000-06-21 |
2023-08-12 |
human |
| H Hassan, W Pohle, H Rüthrich, R Brödemann, M Kru. Repeated long-term potentiation induces mossy fibre sprouting and changes the sensibility of hippocampal granule cells to subconvulsive doses of pentylenetetrazol. The European journal of neuroscience. vol 12. issue 4. 2000-06-21. PMID:10762379. |
the results further demonstrate that morphological and functional changes in the hippocampus, similar to those seen after kindling, can also occur in an activation paradigm leading to long-lasting synaptic plasticity but not accompanied by seizure activity. |
2000-06-21 |
2023-08-12 |
rat |
| N Itokazu, Y Ikegaya, M Nishikawa, N Matsuk. Bidirectional actions of docosahexaenoic acid on hippocampal neurotransmissions in vivo. Brain research. vol 862. issue 1-2. 2000-06-21. PMID:10799687. |
furthermore, we investigated the effect of dha on hippocampal synaptic plasticity. |
2000-06-21 |
2023-08-12 |
rat |
| M J Sanders, T J Sick, M A Perez-Pinzon, W D Dietrich, E J Gree. Chronic failure in the maintenance of long-term potentiation following fluid percussion injury in the rat. Brain research. vol 861. issue 1. 2000-06-06. PMID:10751566. |
experimentally induced tbi is associated with deficits in hippocampal synaptic plasticity (long-term potentiation, or ltp) at acute post-injury intervals but plasticity has not been examined at long-term survival periods. |
2000-06-06 |
2023-08-12 |
rat |
| M J Sanders, T J Sick, M A Perez-Pinzon, W D Dietrich, E J Gree. Chronic failure in the maintenance of long-term potentiation following fluid percussion injury in the rat. Brain research. vol 861. issue 1. 2000-06-06. PMID:10751566. |
these experiments reveal a previously unknown effect of tbi whereby experimentally induced injury results in a chronic inability of the ca1 hippocampus to maintain synaptic plasticity. |
2000-06-06 |
2023-08-12 |
rat |
| B C Albensi, P G Sullivan, M B Thompson, S W Scheff, M P Mattso. Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity. Experimental neurology. vol 162. issue 2. 2000-05-23. PMID:10739643. |
cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity. |
2000-05-23 |
2023-08-12 |
rat |
| B C Albensi, P G Sullivan, M B Thompson, S W Scheff, M P Mattso. Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity. Experimental neurology. vol 162. issue 2. 2000-05-23. PMID:10739643. |
post-tbi administration of cyclosporin a, a compound that stabilizes mitochondrial function, resulted in a highly significant amelioration of the impairment of ltp and completely prevented the enhancement of ltd. our data suggest that alterations in hippocampal synaptic plasticity may be responsible for learning and memory deficits resulting from tbi and that agents such as cyclosporin a that stabilize mitochondrial function may be effective treatments for tbi. |
2000-05-23 |
2023-08-12 |
rat |
| C A Stewart, I C Rei. Repeated ECS and fluoxetine administration have equivalent effects on hippocampal synaptic plasticity. Psychopharmacology. vol 148. issue 3. 2000-04-27. PMID:10755734. |
repeated ecs and fluoxetine administration have equivalent effects on hippocampal synaptic plasticity. |
2000-04-27 |
2023-08-12 |
rat |
| M Korte, L Minichiello, R Klein, T Bonhoeffe. Shc-binding site in the TrkB receptor is not required for hippocampal long-term potentiation. Neuropharmacology. vol 39. issue 5. 2000-04-12. PMID:10699438. |
we found that homo- and heterozygous mutant mice show no difference in the induction-rate or magnitude of e-ltp and l-ltp induced by theta-burst or tetanus stimulation, suggesting that the shc-binding site in the trkb receptor and its downstream activated signaling cascade is not involved in hippocampal synaptic plasticity. |
2000-04-12 |
2023-08-12 |
mouse |
| Q S Chen, B L Kagan, Y Hirakura, C W Xi. Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. Journal of neuroscience research. vol 60. issue 1. 2000-04-12. PMID:10723069. |
our findings demonstrated that subneurotoxic concentrations of abeta peptides could strongly suppress long-term synaptic plasticity in the hippocampus. |
2000-04-12 |
2023-08-12 |
rat |
| K Miyaguchi, Y Maeda, C Collin, R K Siha. Gene transfer into hippocampal slice cultures with an adenovirus vector driven by cytomegalovirus promoter: stable co-expression of green fluorescent protein and lacZ genes. Brain research bulletin. vol 51. issue 3. 2000-03-30. PMID:10718511. |
virus-mediated gene transfer into identified neurons of organotypic hippocampal slice cultures offers a great potential for studying the cellular and molecular mechanisms of synaptic plasticity. |
2000-03-30 |
2023-08-12 |
rat |
| Y Hayashi, S H Shi, J A Esteban, A Piccini, J C Poncer, R Malino. Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science (New York, N.Y.). vol 287. issue 5461. 2000-03-30. PMID:10731148. |
to elucidate mechanisms that control and execute activity-dependent synaptic plasticity, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors (ampa-rs) with an electrophysiological tag were expressed in rat hippocampal neurons. |
2000-03-30 |
2023-08-12 |
rat |
| R Gerlai, A McNamar. Anesthesia induced retrograde amnesia is ameliorated by ephrinA5-IgG in mice: EphA receptor tyrosine kinases are involved in mammalian memory. Behavioural brain research. vol 108. issue 2. 2000-03-21. PMID:10701657. |
recently, however, these proteins were shown to be expressed in the adult mouse brain, primarily in the hippocampus, and were implicated in hippocampal synaptic plasticity and learning. |
2000-03-21 |
2023-08-12 |
mouse |
| C Papatheodoropoulos, G Kostopoulo. Decreased ability of rat temporal hippocampal CA1 region to produce long-term potentiation. Neuroscience letters. vol 279. issue 3. 2000-03-17. PMID:10688058. |
these results suggest that a significant functional differentiation at the local synaptic plasticity level occurs between the two poles of hippocampus, which together with the substantial differences in their extrinsic connections, may help explain the reported differential participation of neurons in these parts of hippocampus during animal memory tests. |
2000-03-17 |
2023-08-12 |
rat |
| Y Nakagami, K Abe, N Nishiyama, N Matsuk. Laminin degradation by plasmin regulates long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 5. 2000-03-09. PMID:10684901. |
to explore the possibility that the pa-plasmin system regulates synaptic plasticity, we investigated the effect of plasmin on degradation of ecm and synaptic plasticity by using organotypic hippocampal cultures. |
2000-03-09 |
2023-08-12 |
Not clear |
| P R Blanque. Identification of two persistently activated neurotrophin-regulated pathways in rat hippocampus. Neuroscience. vol 95. issue 3. 2000-03-01. PMID:10670437. |
brain-derived neurotrophic factor contributes profoundly to modulate activity-dependent synaptic plasticity in adult brain areas such as the hippocampus, but the mechanisms underlying this important role still remain unclear. |
2000-03-01 |
2023-08-12 |
rat |
| P R Blanque. Casein kinase 2 as a potentially important enzyme in the nervous system. Progress in neurobiology. vol 60. issue 3. 2000-02-25. PMID:10658642. |
at present, with respect to recent findings, four essential features suggest potentially important roles for this enzyme in specific neural functions: (1) ck2 is much more abundant in brain than in any other tissue; (2) there appear to be a myriad of substrates for ck2 in both synaptic and nuclear compartments that have clear implications in development, neuritogenesis, synaptic transmission, synaptic plasticity, information storage and survival; (3) ck2 seems to be associated with mechanisms underlying long-term potentiation in hippocampus; and (4) neurotrophins stimulate activity of ck2 in hippocampus. |
2000-02-25 |
2023-08-12 |
Not clear |
| A R Costenla, A de Mendonça, J A Ribeir. Adenosine modulates synaptic plasticity in hippocampal slices from aged rats. Brain research. vol 851. issue 1-2. 2000-02-24. PMID:10642848. |
adenosine modulates synaptic plasticity in hippocampal slices from aged rats. |
2000-02-24 |
2023-08-12 |
rat |
| A R Costenla, A de Mendonça, J A Ribeir. Adenosine modulates synaptic plasticity in hippocampal slices from aged rats. Brain research. vol 851. issue 1-2. 2000-02-24. PMID:10642848. |
adenosine is known to modulate synaptic plasticity in the hippocampus of young animals through activation of adenosine a1 receptors. |
2000-02-24 |
2023-08-12 |
rat |