| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Thibault, R Hadley, P W Landfiel. Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11739583. |
elevated postsynaptic [ca2+]i and l-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. |
2002-01-23 |
2023-08-12 |
rat |
| O Thibault, R Hadley, P W Landfiel. Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11739583. |
however, it is still not known whether (1) intracellular [ca(2+)](i) is altered in aged brain neurons during synaptically activated neuronal activity; (2) altered [ca(2+)](i) is directly correlated with impaired neuronal plasticity; or (3) the previously observed age-related increase in l-type voltage-sensitive ca(2+) channel (l-vscc) density in hippocampal neurons is sufficient to impair synaptic plasticity. |
2002-01-23 |
2023-08-12 |
rat |
| B D Philpot, M P Weisberg, M S Ramos, N B Sawtell, Y P Tang, J Z Tsien, M F Bea. Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Neuropharmacology. vol 41. issue 6. 2002-01-10. PMID:11640931. |
unlike the hippocampus, in vitro synaptic plasticity of the visual cortex was unaltered by nr2b overexpression. |
2002-01-10 |
2023-08-12 |
mouse |
| M Kokaia, K Holmberg, A Nanobashvili, Z Q Xu, Z Kokaia, U Lendahl, S Hilke, E Theodorsson, U Kahl, T Bartfai, O Lindvall, T Hökfel. Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 24. 2002-01-08. PMID:11698649. |
frequency facilitation of field excitatory postsynaptic potentials, a form of short-term synaptic plasticity assessed in hippocampal slices, was reduced in mossy fiber-ca3 cell synapses of galanin-overexpressing mice, indicating suppressed glutamate release. |
2002-01-08 |
2023-08-12 |
mouse |
| N Mons, V Enderlin, R Jaffard, P Higuere. Selective age-related changes in the PKC-sensitive, calmodulin-binding protein, neurogranin, in the mouse brain. Journal of neurochemistry. vol 79. issue 4. 2001-12-20. PMID:11723178. |
these data suggest that age-related changes of post-synaptic ng in selected brain areas, and particularly in hippocampus, may contribute to altered ca(2+)/calmodulin-signalling pathways and to region-specific impairments of synaptic plasticity and cognitive decline. |
2001-12-20 |
2023-08-12 |
mouse |
| M D Glitsch, J J Jac. Evidence that glutamate acting on presynaptic type-II metabotropic glutamate receptors alone does not fully account for the phenomenon of depolarisation-induced suppression of inhibition in cerebellar Purkinje cells. Pflugers Archiv : European journal of physiology. vol 442. issue 3. 2001-12-12. PMID:11484772. |
depolarisation-induced suppression of inhibition (dsi) is a form of short-term synaptic plasticity at gamma-aminobutyric-acid-(gaba)ergic synapses between principal neurons and interneurons in both the cerebellum and the hippocampus. |
2001-12-12 |
2023-08-12 |
Not clear |
| K Ab. Modulation of hippocampal long-term potentiation by the amygdala: a synaptic mechanism linking emotion and memory. Japanese journal of pharmacology. vol 86. issue 1. 2001-12-07. PMID:11430468. |
in addition, we have obtained direct evidence that neural inputs from the amygdala modulate synaptic plasticity in the hippocampus, through electrophysiological experiments using anesthetized rats. |
2001-12-07 |
2023-08-12 |
rat |
| S Chirwa, J Mack, R Park, K Dennis, A Aduonu. An in vivo model for investigating bilateral synaptic plasticity across CA3/CA1 synapses in guinea pig dorsal hippocampus. Journal of neuroscience methods. vol 110. issue 1-2. 2001-12-07. PMID:11564521. |
an in vivo model for investigating bilateral synaptic plasticity across ca3/ca1 synapses in guinea pig dorsal hippocampus. |
2001-12-07 |
2023-08-12 |
Not clear |
| M Y Xiao, Y P Niu, M Dozmorov, H Wigströ. Comparing fluctuations of synaptic responses mediated via AMPA and NMDA receptor channels--implications for synaptic plasticity. Bio Systems. vol 62. issue 1-3. 2001-12-07. PMID:11595318. |
the present paper summarizes and discusses these results in relation to current theories on hippocampal synaptic plasticity, especially with regard to the ideas of glutamate spillover and silent synapses. |
2001-12-07 |
2023-08-12 |
rat |
| C Job, J Eberwin. Identification of sites for exponential translation in living dendrites. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 23. 2001-12-07. PMID:11606784. |
neuronal processes contain mrnas and membrane structures, and some forms of synaptic plasticity seem to require protein synthesis in dendrites of hippocampal neurons. |
2001-12-07 |
2023-08-12 |
Not clear |
| R Gutiérrez, P Leff, H Romo-Parra, R Acevedo, B Antó. Orphanin-FQ/nociceptin inhibits kindling epileptogenesis and enhances hippocampal feed-forward inhibition. Neuroscience. vol 105. issue 2. 2001-12-07. PMID:11672600. |
the role of orphanin-fq/nociceptin in synaptic plasticity was assessed by its potency in modulating kindling epileptogenesis in vivo, and feed-forward inhibition in hippocampal recordings in vitro. |
2001-12-07 |
2023-08-12 |
rat |
| I E Kudryashov, I V Kudryashov. The effects of forelimb deafferentation on the post-natal development of synaptic plasticity in the hippocampus. Neuroscience and behavioral physiology. vol 31. issue 3. 2001-12-04. PMID:11430575. |
the effects of forelimb deafferentation on the post-natal development of synaptic plasticity in the hippocampus. |
2001-12-04 |
2023-08-12 |
rat |
| M F Pérez, F J Nasif, G R Marchesini, L E Maglio, O A Ramire. Hippocampus and locus coeruleus activity on rats chronically treated with diazepam. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509201. |
the results of our study showed an increased hippocampal synaptic plasticity in slices from rats chronically treated with dz (5 mg/kg/18 days), assessed as a decrease of the threshold in the stimulation rate for long-term potentiation (ltp) elicitation. |
2001-12-04 |
2023-08-12 |
rat |
| M F Pérez, F J Nasif, G R Marchesini, L E Maglio, O A Ramire. Hippocampus and locus coeruleus activity on rats chronically treated with diazepam. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509201. |
we conclude that chronic dz administration enhances both hippocampal synaptic plasticity and activity of lc-ne neurons. |
2001-12-04 |
2023-08-12 |
rat |
| J C Von Frijtag, A Kamal, L G Reijmers, L H Schrama, R van den Bos, B M Spruij. Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514064. |
chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats. |
2001-12-04 |
2023-08-12 |
rat |
| J C Von Frijtag, A Kamal, L G Reijmers, L H Schrama, R van den Bos, B M Spruij. Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514064. |
in the present study, we investigated whether synaptic plasticity changes in the hippocampus of depressive-like socially stressed rats could be reversed by chronic antidepressant treatment. |
2001-12-04 |
2023-08-12 |
rat |
| J C Von Frijtag, A Kamal, L G Reijmers, L H Schrama, R van den Bos, B M Spruij. Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514064. |
the altered synaptic plasticity after social stress is discussed in relation to cognitive deficits and hippocampal changes that are observed in depressive patients. |
2001-12-04 |
2023-08-12 |
rat |
| D L Misner, S Jacobs, Y Shimizu, A M de Urquiza, L Solomin, T Perlmann, L M De Luca, C F Stevens, R M Evan. Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 20. 2001-12-04. PMID:11553775. |
vitamin a deprivation results in reversible loss of hippocampal long-term synaptic plasticity. |
2001-12-04 |
2023-08-12 |
mouse |
| T Mizuno, I Kanazawa, M Sakura. Differential induction of LTP and LTD is not determined solely by instantaneous calcium concentration: an essential involvement of a temporal factor. The European journal of neuroscience. vol 14. issue 4. 2001-11-01. PMID:11556894. |
two opposite types of synaptic plasticity in the ca1 hippocampus, long-term potentiation (ltp) and long-term depression (ltd), require postsynaptic ca2+ elevation. |
2001-11-01 |
2023-08-12 |
rat |
| Y Zheng, A Horii, I Appleton, C L Darlington, P F Smit. Damage to the vestibular inner ear causes long-term changes in neuronal nitric oxide synthase expression in the rat hippocampus. Neuroscience. vol 105. issue 1. 2001-09-27. PMID:11483295. |
since nitric oxide has been implicated in the mechanisms of hippocampal synaptic plasticity associated with the development of short-term memory (e.g. |
2001-09-27 |
2023-08-12 |
rat |