| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher Rong. A fresh look at the role of CaMKII in hippocampal synaptic plasticity and memory. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 24. issue 3. 2002-04-09. PMID:11891759. |
a fresh look at the role of camkii in hippocampal synaptic plasticity and memory. |
2002-04-09 |
2023-08-12 |
mouse |
| Amanda M Vanhoose, Megan Emery, Lismary Jimenez, Danny G Winde. ERK activation by G-protein-coupled receptors in mouse brain is receptor identity-specific. The Journal of biological chemistry. vol 277. issue 11. 2002-04-05. PMID:11782465. |
in transfected cells and non-neuronal tissues many g-protein-coupled receptors activate p44/42 map kinase (erk), a kinase involved in both hippocampal synaptic plasticity and learning and memory. |
2002-04-05 |
2023-08-12 |
mouse |
| Amanda M Vanhoose, Megan Emery, Lismary Jimenez, Danny G Winde. ERK activation by G-protein-coupled receptors in mouse brain is receptor identity-specific. The Journal of biological chemistry. vol 277. issue 11. 2002-04-05. PMID:11782465. |
g(s)-coupled beta-adrenergic receptor activation of erk in neurons is critical in the regulation of synaptic plasticity in area ca1 of the hippocampus. |
2002-04-05 |
2023-08-12 |
mouse |
| Edda Thiels, Beatriz I Kanterewicz, Eric D Norman, James M Trzaskos, Eric Klan. Long-term depression in the adult hippocampus in vivo involves activation of extracellular signal-regulated kinase and phosphorylation of Elk-1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 6. 2002-03-27. PMID:11896145. |
our findings indicate that the erk cascade transduces signals from the synapse to the nucleus during ltd in hippocampal area ca1 in vivo, as it does during long-term potentiation in area ca1, but that the pattern of coupling of the erk cascade to transcriptional regulators differs between the two forms of synaptic plasticity. |
2002-03-27 |
2023-08-12 |
rat |
| Robin A Morton, Frederick M Kuenzi, Stephen M Fitzjohn, Thomas W Rosahl, David Smith, Hui Zheng, Mark Shearman, Graham L Collingridge, Guy R Seabroo. Impairment in hippocampal long-term potentiation in mice under-expressing the Alzheimer's disease related gene presenilin-1. Neuroscience letters. vol 319. issue 1. 2002-03-25. PMID:11814648. |
we have utilised genetically modified mice that under-express ps1 (ps1(+/-) mice) to investigate the role of ps1 in hippocampal synaptic plasticity. |
2002-03-25 |
2023-08-12 |
mouse |
| Shui-Wang Ying, Marie Futter, Kobi Rosenblum, Mark J Webber, Stephen P Hunt, Timothy V P Bliss, Clive R Bramha. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 5. 2002-03-22. PMID:11880483. |
brain-derived neurotrophic factor (bdnf) is implicated in long-term synaptic plasticity in the adult hippocampus, but the cellular mechanisms are little understood. |
2002-03-22 |
2023-08-12 |
Not clear |
| Lu Pu, Guo-Bin Bao, Nan-Jie Xu, Lan Ma, Gang Pe. Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by re-exposure to opiates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 5. 2002-03-22. PMID:11880521. |
given the known effects of opiates such as morphine and heroin on hippocampal function, we investigated the potential effect of chronic opiate treatment on long-term potentiation (ltp) at ca1 synapses in rat hippocampus, a leading experimental model for studying synaptic plasticity. |
2002-03-22 |
2023-08-12 |
rat |
| Lu Pu, Guo-Bin Bao, Nan-Jie Xu, Lan Ma, Gang Pe. Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by re-exposure to opiates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 5. 2002-03-22. PMID:11880521. |
these findings demonstrated that chronic opiate treatment can significantly modulate synaptic plasticity in the hippocampus, leading to an opiate dependence of the plasticity. |
2002-03-22 |
2023-08-12 |
rat |
| Alexander Kulla, Denise Manahan-Vaugha. Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats. Cerebral cortex (New York, N.Y. : 1991). vol 12. issue 2. 2002-03-14. PMID:11739263. |
these results strongly support a role for 5-ht(4) receptors in hippocampal synaptic plasticity and provide an important link to findings with regard to the involvement of 5-ht in processes related to learning and memory. |
2002-03-14 |
2023-08-12 |
rat |
| Lauren T Knapp, Eric Klan. Potentiation of hippocampal synaptic transmission by superoxide requires the oxidative activation of protein kinase C. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826097. |
potentiation of hippocampal synaptic transmission by superoxide requires the oxidative activation of protein kinase c. recent evidence suggests that reactive oxygen species (ros), including superoxide, are not only neurotoxic but function as small messenger molecules in normal neuronal processes such as synaptic plasticity. |
2002-02-27 |
2023-08-12 |
Not clear |
| Inah Lee, Raymond P Kesne. Differential contribution of NMDA receptors in hippocampal subregions to spatial working memory. Nature neuroscience. vol 5. issue 2. 2002-02-26. PMID:11780144. |
n-methyl-d-aspartate (nmda) receptor-dependent synaptic plasticity in the mammalian hippocampus is essential for learning and memory. |
2002-02-26 |
2023-08-12 |
mouse |
| R Tonini, S Franceschetti, D Parolaro, M Sala, E Mancinelli, S Tininini, R Brusetti, G Sancini, R Brambilla, E Martegani, E Sturani, R Zippe. Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability. Molecular and cellular neurosciences. vol 18. issue 6. 2002-02-21. PMID:11749043. |
mice lacking ras-grf1 (-/-) are severely impaired in amygdala-dependent long-term synaptic plasticity and show higher basal synaptic activity at both amygdala and hippocampal synapses (brambilla et al., 1997). |
2002-02-21 |
2023-08-12 |
mouse |
| J F MacDonald, S A Kotecha, W Y Lu, M F Jackso. Convergence of PKC-dependent kinase signal cascades on NMDA receptors. Current drug targets. vol 2. issue 3. 2002-02-19. PMID:11554554. |
synaptic plasticity, or long-term potentiation (ltp), of excitatory synapses in the hippocampus contributes to learning and the establishment of spatial memories. |
2002-02-19 |
2023-08-12 |
Not clear |
| M R Fo. 17beta-estradiol: effect on CA1 hippocampal synaptic plasticity. Neurobiology of learning and memory. vol 76. issue 3. 2002-01-31. PMID:11726235. |
17beta-estradiol: effect on ca1 hippocampal synaptic plasticity. |
2002-01-31 |
2023-08-12 |
Not clear |
| M R Fo. 17beta-estradiol: effect on CA1 hippocampal synaptic plasticity. Neurobiology of learning and memory. vol 76. issue 3. 2002-01-31. PMID:11726235. |
this paper reviews the recent results that have led to a better understanding of how the sex hormone estrogen influences synaptic plasticity in an important structure within the mammalian brain responsible for learning and memory: the hippocampus. |
2002-01-31 |
2023-08-12 |
Not clear |
| M J Kahana, D Seelig, J R Madse. Theta returns. Current opinion in neurobiology. vol 11. issue 6. 2002-01-28. PMID:11741027. |
recent physiological studies have implicated theta - a high-amplitude 4-8 hz oscillation that is prominent in rat hippocampus during locomotion, orienting and other voluntary behaviors - in synaptic plasticity, information coding and the function of working memory. |
2002-01-28 |
2023-08-12 |
human |
| M W Jones, H M Peckham, M L Errington, T V Bliss, A Routtenber. Synaptic plasticity in the hippocampus of awake C57BL/6 and DBA/2 mice: interstrain differences and parallels with behavior. Hippocampus. vol 11. issue 4. 2002-01-23. PMID:11530843. |
synaptic plasticity in the hippocampus of awake c57bl/6 and dba/2 mice: interstrain differences and parallels with behavior. |
2002-01-23 |
2023-08-12 |
mouse |
| L J Shanley, A J Irving, J Harve. Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11734601. |
leptin enhances nmda receptor function and modulates hippocampal synaptic plasticity. |
2002-01-23 |
2023-08-12 |
Not clear |
| L J Shanley, A J Irving, J Harve. Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11734601. |
in the hippocampus, an area of the brain involved in learning and memory, we have found that leptin facilitates the induction of synaptic plasticity. |
2002-01-23 |
2023-08-12 |
Not clear |
| L J Shanley, A J Irving, J Harve. Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11734601. |
these data indicate that a novel action of leptin in the cns is to facilitate hippocampal synaptic plasticity via enhanced nmda receptor-mediated ca(2+) influx. |
2002-01-23 |
2023-08-12 |
Not clear |