| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Krazem, Nicole Mons, Paul Higueret, Robert Jaffar. Chronic ethanol consumption restores the age-related decrease in neurogranin mRNA level in the hippocampus of mice. Neuroscience letters. vol 338. issue 1. 2003-04-10. PMID:12565141. |
on the basis of recent data indicating a central role for ng in the regulation of hippocampal synaptic plasticity and spatial learning, our results suggest that moderate ethanol consumption might have a beneficial influence on cognitive deterioration during senescence. |
2003-04-10 |
2023-08-12 |
mouse |
| Marzia Malcangio, Volkmar Lessman. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends in pharmacological sciences. vol 24. issue 3. 2003-04-08. PMID:12628355. |
in the schaffer collateral pathway of the hippocampus, binding of bdnf to high-affinity trkb receptors is essential for the induction of long-term potentiation, a specific type of synaptic plasticity. |
2003-04-08 |
2023-08-12 |
Not clear |
| Carlos Matias, José C Dionísio, M Emília Quinta-Ferreir. Thapsigargin blocks STP and LTP related calcium enhancements in hippocampal CA1 area. Neuroreport. vol 13. issue 18. 2003-04-04. PMID:12499871. |
multiple calcium signaling pathways, including intracellular calcium release that is mediated by inositol triphosphate (ip3) or ryanodine calcium store receptors, seem to be involved in ca1 hippocampal synaptic plasticity. |
2003-04-04 |
2023-08-12 |
Not clear |
| Maeng-Hee Kang-Park, Meredith A Sarda, Katherine H Jones, Scott D Moore, Shirish Shenolikar, Suzanne Clark, Wilkie A Wilso. Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation. Journal of neurophysiology. vol 89. issue 2. 2003-04-04. PMID:12574446. |
we have previously reported that varying stimulus intensity produces qualitatively different types of synaptic plasticity in area ca1 of hippocampal slices: brief low-intensity (li) theta-burst (tb) stimuli induce long-term potentiation (ltp), but if the stimulus intensity is increased (to mimic conditions that may exist during seizures), ltp is not induced; instead, high-intensity (hi) tb stimuli erase previously induced ltp ("tb depotentiation"). |
2003-04-04 |
2023-08-12 |
rat |
| Maeng-Hee Kang-Park, Meredith A Sarda, Katherine H Jones, Scott D Moore, Shirish Shenolikar, Suzanne Clark, Wilkie A Wilso. Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation. Journal of neurophysiology. vol 89. issue 2. 2003-04-04. PMID:12574446. |
these results suggest that protein phosphatase pathways are involved in the tb depotentiation similar to other type of down-regulating synaptic plasticity such as low-frequency stimulation (lfs)-induced long-term depression (ltd) and depotentiation in the rat hippocampus. |
2003-04-04 |
2023-08-12 |
rat |
| Christelle L M Bon, John Garthwait. On the role of nitric oxide in hippocampal long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629199. |
nitric oxide (no) functions in several types of synaptic plasticity, including hippocampal long-term potentiation (ltp), in which it may serve as a retrograde messenger after postsynaptic nmda receptor activation. |
2003-03-24 |
2023-08-12 |
rat |
| Cyrille Vaillend, Jean-Marie Billar. Facilitated CA1 hippocampal synaptic plasticity in dystrophin-deficient mice: role for GABAA receptors? Hippocampus. vol 12. issue 6. 2003-03-21. PMID:12542223. |
facilitated ca1 hippocampal synaptic plasticity in dystrophin-deficient mice: role for gabaa receptors? |
2003-03-21 |
2023-08-12 |
mouse |
| Angela Ho, Wade Morishita, Robert E Hammer, Robert C Malenka, Thomas C Sudho. A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 3. 2003-03-18. PMID:12547917. |
in electrophysiological recordings in the hippocampus, we observed no changes in short- or long-term synaptic plasticity in excitatory synapses from mint 1-deficient mice and detected no alterations in the ratio of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) to n-methyl-d-aspartate (nmda) receptor-mediated synaptic currents. |
2003-03-18 |
2023-08-12 |
mouse |
| Nicholas Brandon, Jasmina Jovanovic, Stephen Mos. Multiple roles of protein kinases in the modulation of gamma-aminobutyric acid(A) receptor function and cell surface expression. Pharmacology & therapeutics. vol 94. issue 1-2. 2003-03-13. PMID:12191597. |
moreover, changes in the efficacy of synaptic inhibition mediated by gaba(a) receptors are believed to be play central roles in certain forms of synaptic plasticity, including rebound potentiation in the cerebellum, and hippocampal long-term potentiation. |
2003-03-13 |
2023-08-12 |
Not clear |
| Yuji Ikegaya, Isabelle Delcroix, Yoichiro Iwakura, Norio Matsuki, Nobuyoshi Nishiyam. Interleukin-1beta abrogates long-term depression of hippocampal CA1 synaptic transmission. Synapse (New York, N.Y.). vol 47. issue 1. 2003-03-07. PMID:12422373. |
although interleukin-1beta (il-1beta) is well known to modulate synaptic transmission and plasticity of the hippocampus, no study has yet evaluated how this cytokine affects long-term depression (ltd), one of the major forms of hippocampal synaptic plasticity. |
2003-03-07 |
2023-08-12 |
Not clear |
| Mariana Alonso, Monica R M Vianna, Amaicha M Depino, Tadeu Mello e Souza, Patricia Pereira, German Szapiro, Haydee Viola, Fernando Pitossi, Ivan Izquierdo, Jorge H Medin. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201640. |
because brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, we examined the role of bdnf in stm and ltm formation of a hippocampal-dependent one-trial fear-motivated learning task in rats. |
2003-03-05 |
2023-08-12 |
human |
| Janet Alder, Smita Thakker-Varia, Ira B Blac. Transcriptional analysis in the brain: trophin-induced hippocampal synaptic plasticity. Neurochemical research. vol 27. issue 10. 2003-01-27. PMID:12462406. |
transcriptional analysis in the brain: trophin-induced hippocampal synaptic plasticity. |
2003-01-27 |
2023-08-12 |
Not clear |
| Janet Alder, Smita Thakker-Varia, Ira B Blac. Transcriptional analysis in the brain: trophin-induced hippocampal synaptic plasticity. Neurochemical research. vol 27. issue 10. 2003-01-27. PMID:12462406. |
we have employed a multidisciplinary approach using whole cell patch clamp recording and transcriptional analysis to define the genomic basis of trophin-induced hippocampal synaptic plasticity. |
2003-01-27 |
2023-08-12 |
Not clear |
| K M Frick, S M Fernandez, S C Bulinsk. Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421621. |
the results suggest that: (1) estrogen can profoundly improve spatial reference memory in aged females, and (2) this improvement may be related to increased hippocampal synaptic plasticity, but not modulation of the synthetic enzymes for acetylcholine and gaba. |
2003-01-23 |
2023-08-12 |
mouse |
| Sidarta Ribeiro, Claudio V Mello, Tarciso Velho, Timothy J Gardner, Erich D Jarvis, Constantine Pavlide. Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 24. 2003-01-23. PMID:12486186. |
thus, expression of an activity-dependent gene involved in synaptic plasticity propagates gradually from the hippocampus to extrahippocampal regions as rem sleep recurs. |
2003-01-23 |
2023-08-12 |
rat |
| Maurizio Popoli, Massimo Gennarelli, Giorgio Racagn. Modulation of synaptic plasticity by stress and antidepressants. Bipolar disorders. vol 4. issue 3. 2003-01-17. PMID:12180272. |
in the hippocampus, a main area of the limbic system involved in cognitive functions as well as attention and affect, specific molecules enriched at glutamatergic synapses mediate major changes in synaptic plasticity induced by stress paradigms or antidepressant treatments. |
2003-01-17 |
2023-08-12 |
Not clear |
| Maurizio Popoli, Massimo Gennarelli, Giorgio Racagn. Modulation of synaptic plasticity by stress and antidepressants. Bipolar disorders. vol 4. issue 3. 2003-01-17. PMID:12180272. |
we analyze here the modifications induced by stress or antidepressants in the strength of synaptic transmission in hippocampus, and the molecular modifications induced by antidepressants in two main mediators of synaptic plasticity: the n-methyl-d-aspartate (nmda) receptor complex for glutamate and the ca2+/calmodulin-dependent protein kinase ii (cam kinase ii). |
2003-01-17 |
2023-08-12 |
Not clear |
| Lawrence P Reagan, Bruce S McEwe. Diabetes, but not stress, reduces neuronal nitric oxide synthase expression in rat hippocampus: implications for hippocampal synaptic plasticity. Neuroreport. vol 13. issue 14. 2003-01-15. PMID:12395127. |
diabetes, but not stress, reduces neuronal nitric oxide synthase expression in rat hippocampus: implications for hippocampal synaptic plasticity. |
2003-01-15 |
2023-08-12 |
rat |
| Lawrence P Reagan, Bruce S McEwe. Diabetes, but not stress, reduces neuronal nitric oxide synthase expression in rat hippocampus: implications for hippocampal synaptic plasticity. Neuroreport. vol 13. issue 14. 2003-01-15. PMID:12395127. |
these results suggest that: (1) decreased expression of nnos mrna and protein may contribute to deficits in hippocampal dependent learning and ltp in diabetic rats; and (2) other mechanisms may be involved in stress mediated decreases in hippocampal synaptic plasticity. |
2003-01-15 |
2023-08-12 |
rat |
| Jennifer L Berkeley, Allan I Leve. Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus. Molecular pharmacology. vol 63. issue 1. 2003-01-09. PMID:12488545. |
because erk is an important component in the regulation of synaptic plasticity, in this study we examined erk activation by three families of gpcr that respond to major neuromodulatory neurotransmitters in the hippocampus. |
2003-01-09 |
2023-08-12 |
mouse |