| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claudius E Degro, Akos Kulik, Sam A Booker, Imre Vid. Compartmental distribution of GABAB receptor-mediated currents along the somatodendritic axis of hippocampal principal cells. Frontiers in synaptic neuroscience. vol 7. 2015-04-08. PMID:25852540. |
these data demonstrate a compartmentalized distribution of the gababr-kir3 signaling cascade and suggest differential control of synaptic transmission, dendritic integration and synaptic plasticity at afferent pathways onto hippocampal principal cells. |
2015-04-08 |
2023-08-13 |
rat |
| Lauren C Harte-Hargrove, Ada Varga-Wesson, Aine M Duffy, Teresa A Milner, Helen E Scharfma. Opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 4. 2015-04-07. PMID:25632146. |
opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat. |
2015-04-07 |
2023-08-13 |
rat |
| C A Bostrom, N-M Majaess, K Morch, E White, B D Eadie, B R Christi. Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 1. 2015-04-06. PMID:23968838. |
we report that a loss of fmrp leads to impairments in n-methyl-d-aspartate receptor (nmdar)-dependent synaptic plasticity in the dentate gyrus (dg), but not in the cornu ammonis area 1 (ca1) subregion of the hippocampus of adult mice. |
2015-04-06 |
2023-08-12 |
mouse |
| Andrea C Paula-Lima, Tatiana Adasme, Cecilia Hidalg. Contribution of Ca2+ release channels to hippocampal synaptic plasticity and spatial memory: potential redox modulation. Antioxidants & redox signaling. vol 21. issue 6. 2015-04-02. PMID:24410659. |
contribution of ca2+ release channels to hippocampal synaptic plasticity and spatial memory: potential redox modulation. |
2015-04-02 |
2023-08-12 |
human |
| Pakzad Fathpour, Nina Obad, Heidi Espedal, Daniel Stieber, Olivier Keunen, Per Ø Sakariassen, Simone P Niclou, Rolf Bjerkvi. Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment? Neuro-oncology. vol 16. issue 5. 2015-03-31. PMID:24733853. |
in the present work we point at the possibility that bevacizumab treatment of the normal brain can reduce synaptic plasticity in the hippocampus. |
2015-03-31 |
2023-08-13 |
human |
| Silvia Alboni, Claudia Montanari, Cristina Benatti, Manuel Sanchez-Alavez, Giovanna Rigillo, Joan M C Blom, Nicoletta Brunello, Bruno Conti, M Carmine Pariante, Fabio Tascedd. Interleukin 18 activates MAPKs and STAT3 but not NF-κB in hippocampal HT-22 cells. Brain, behavior, and immunity. vol 40. 2015-03-30. PMID:24603356. |
this effect may help to explain some of the il-18-induced effects on synaptic plasticity and functionality within the hippocampal system. |
2015-03-30 |
2023-08-12 |
mouse |
| Christine Manrique, Martine Migliorati, Valérie Gilbert, Jean-Michel Brezun, Franck A Chaillan, Bruno Truchet, Michel Khrestchatisky, Gaëlle Guiraudie-Capraz, François S Roma. Dynamic expression of the polysialyltransferase in adult rat hippocampus performing an olfactory associative task. Hippocampus. vol 24. issue 8. 2015-03-30. PMID:24753009. |
psa-ncam plays an important role in synaptic plasticity in the hippocampus. |
2015-03-30 |
2023-08-13 |
rat |
| Martine R Groen, Ole Paulsen, Enrique Pérez-Garci, Thomas Nevian, J Wortel, Marinus P Dekker, Huibert D Mansvelder, Arjen van Ooyen, Rhiannon M Meredit. Development of dendritic tonic GABAergic inhibition regulates excitability and plasticity in CA1 pyramidal neurons. Journal of neurophysiology. vol 112. issue 2. 2015-03-30. PMID:24760781. |
synaptic plasticity rules change during development: while hippocampal synapses can be potentiated by a single action potential pairing protocol in young neurons, mature neurons require burst firing to induce synaptic potentiation. |
2015-03-30 |
2023-08-13 |
Not clear |
| Feng Qiao, Xiu-Ping Gao, Li Yuan, Hong-Yan Cai, Jin-Shun Q. Apolipoprotein E4 impairs in vivo hippocampal long-term synaptic plasticity by reducing the phosphorylation of CaMKIIα and CREB. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787920. |
apolipoprotein e4 impairs in vivo hippocampal long-term synaptic plasticity by reducing the phosphorylation of camkiiα and creb. |
2015-03-30 |
2023-08-13 |
Not clear |
| Feng Qiao, Xiu-Ping Gao, Li Yuan, Hong-Yan Cai, Jin-Shun Q. Apolipoprotein E4 impairs in vivo hippocampal long-term synaptic plasticity by reducing the phosphorylation of CaMKIIα and CREB. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787920. |
the results showed that: (1) intra-hippocampal injection of 0.2 μg apoe4, but not apoe2, before high frequency stimulations (hfss) attenuated the induction of hippocampal l-ltp in the ca1 region, while injection of the same concentration of apoe4 after hfss, even at a higher concentration (2 μg), did not affect the long term synaptic plasticity; (2) apoe4 injection did not affect the paired pulse facilitation in the hippocampal ca1 region; (3) apoe4 injection before, not after, hfss significantly decreased the levels of phosphorylated ca2+/calmodulin-dependent protein kinase iiα (p-camkiiα) and phosphorylated camp response element-binding protein (p-creb) in the hippocampus. |
2015-03-30 |
2023-08-13 |
Not clear |
| Feng Qiao, Xiu-Ping Gao, Li Yuan, Hong-Yan Cai, Jin-Shun Q. Apolipoprotein E4 impairs in vivo hippocampal long-term synaptic plasticity by reducing the phosphorylation of CaMKIIα and CREB. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787920. |
these results demonstrated for the first time that apoe4 could impair hippocampal l-ltp by reducing p-camkiiα and p-creb, suggesting that the apoe4-induced suppression of hippocampal long-term synaptic plasticity may contribute to the cognitive impairments in genetic ad; and both camkiiα and creb are important intracellular targets of the neurotoxic apoe4. |
2015-03-30 |
2023-08-13 |
Not clear |
| Tomasz Gorkiewicz, Marcin Balcerzyk, Leszek Kaczmarek, Ewelina Knapsk. Matrix metalloproteinase 9 (MMP-9) is indispensable for long term potentiation in the central and basal but not in the lateral nucleus of the amygdala. Frontiers in cellular neuroscience. vol 9. 2015-03-27. PMID:25814930. |
in particular, mmp-9 involvement in long-term potentiation (ltp, the model of synaptic plasticity) in the hippocampus and prefrontal cortex has previously been demonstrated. |
2015-03-27 |
2023-08-13 |
Not clear |
| Lara Costa, Lara M Sardone, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-03-27. PMID:25814945. |
we have previously shown that 5-ht7 receptors modulate glutamate-mediated hippocampal synaptic transmission and long-term synaptic plasticity. |
2015-03-27 |
2023-08-13 |
mouse |
| Lara Costa, Lara M Sardone, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-03-27. PMID:25814945. |
in this perspective, we have characterized the basic in vitro pharmacokinetic properties of novel molecules with high binding affinity and selectivity for 5-ht7 receptors and we have tested their effects on synaptic plasticity using patch clamp on acute hippocampal slices. |
2015-03-27 |
2023-08-13 |
mouse |
| Di Tian, Laura J Stoppel, Arnold J Heynen, Lothar Lindemann, Georg Jaeschke, Alea A Mills, Mark F Bea. Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion. Nature neuroscience. vol 18. issue 2. 2015-03-24. PMID:25581360. |
using a mouse with the same genetic deficiency, we found that metabotropic glutamate receptor 5 (mglur5)-dependent synaptic plasticity and protein synthesis was altered in the hippocampus and that hippocampus-dependent memory was impaired. |
2015-03-24 |
2023-08-13 |
mouse |
| Yoav Shulman, Alexandra Stavsky, Tatiana Fedorova, Dan Mikulincer, Merav Atias, Igal Radinsky, Joy Kahn, Inna Slutsky, Daniel Gitle. ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 3. 2015-03-24. PMID:25609616. |
we conclude that atp binding to synapsin iia plays a key role in modulating its function and in defining its contribution to hippocampal short-term synaptic plasticity. |
2015-03-24 |
2023-08-13 |
mouse |
| Nobuaki Hori, Tomoko Kadota, Norio Akaik. Functional changes in piriform cortex pyramidal neurons in the chronic methamphetamine-treated rat. General physiology and biophysics. vol 34. issue 1. 2015-03-23. PMID:25367761. |
the changes we observed represent detrimental effects on the function of piriform cortical neurons further illustrating deficits in synaptic plasticity extend beyond the hippocampus. |
2015-03-23 |
2023-08-13 |
rat |
| Hyun-Bum Kim, Byeong-Jae Kwon, Hyun-Ji Cho, Ji-Won Kim, Jeong-Woo Chon, Moon-Ho Do, Sang-Yong Park, Sun-Yeou Kim, Sung-Ho Maeng, Yoo-Kyoung Park, Ji-Ho Par. Long-term Treatment with Oriental Medicinal Herb Artemisia princeps Alters Neuroplasticity in a Rat Model of Ovarian Hormone Deficiency. Experimental neurobiology. vol 24. issue 1. 2015-03-20. PMID:25792871. |
no study has yet assessed its effects on synaptic plasticity in hippocampus and much less in a model of ovarian hormone deficiency. |
2015-03-20 |
2023-08-13 |
rat |
| Fan Hu, Li Xu, Zhi-Hua Liu, Meng-Meng Ge, Di-Yun Ruan, Hui-Li Wan. Developmental lead exposure alters synaptogenesis through inhibiting canonical Wnt pathway in vivo and in vitro. PloS one. vol 9. issue 7. 2015-02-24. PMID:24999626. |
lead (pb) exposure has been implicated in the impairment of synaptic plasticity in the developing hippocampus, but the mechanism remains unclear. |
2015-02-24 |
2023-08-13 |
rat |
| Li-Yun Tsai, Yu-Wei Chang, Pei-Yi Lin, Hsin-Jung Chou, Ta-Jen Liu, Ping-Tao Lee, Wen-Hsuan Huang, Yueh-Liang Tsou, Yi-Shuian Huan. CPEB4 knockout mice exhibit normal hippocampus-related synaptic plasticity and memory. PloS one. vol 8. issue 12. 2015-02-23. PMID:24386439. |
electrophysiological recordings of multiple forms of synaptic plasticity in the schaffer collateral pathway-ca1 neurons also showed normal responses in the ko hippocampal slices. |
2015-02-23 |
2023-08-12 |
mouse |