| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Denise Becker, Benno Ikenberg, Sabine Schiener, Nicola Maggio, Andreas Vlacho. NMDA-receptor inhibition restores Protease-Activated Receptor 1 (PAR1) mediated alterations in homeostatic synaptic plasticity of denervated mouse dentate granule cells. Neuropharmacology. vol 86. 2015-07-14. PMID:25086265. |
here, we used entorhinal denervation of organotypic hippocampal slice cultures to study the effects of par1 on denervation-induced homeostatic synaptic plasticity. |
2015-07-14 |
2023-08-13 |
mouse |
| Paula L McClean, Christian Hölsche. Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease. Neuropharmacology. vol 86. 2015-07-14. PMID:25107586. |
when analysing synaptic plasticity in the hippocampus, ltp was strongly increased in app/ps1 mice by either drug. |
2015-07-14 |
2023-08-13 |
mouse |
| Yukitoshi Izumi, Charles F Zorumsk. Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function. Neuropharmacology. vol 86. 2015-07-14. PMID:25128848. |
in the present studies, we examined the effects of subanesthetic, low micromolar ketamine on excitatory postsynaptic potentials (epsps), population spikes (pss) and synaptic plasticity in the ca1 region of rat hippocampal slices. |
2015-07-14 |
2023-08-13 |
rat |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
the selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. |
2015-07-08 |
2023-08-13 |
rat |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
previously, we showed altered hippocampal synaptic plasticity in an animal model of depression. |
2015-07-08 |
2023-08-13 |
rat |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
accordingly, we evaluated the effect of chronic reboxetine (a selective noradrenergic reuptake inhibitor) treatment on depression-induced reduced hippocampal synaptic plasticity, neurotransmitter levels, and spatial learning and memory impairments. |
2015-07-08 |
2023-08-13 |
rat |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
thus, restoration of hippocampal synaptic plasticity might be a cellular mechanism underlying the beneficial effect of reboxetine in depression-associated cognitive deficits. |
2015-07-08 |
2023-08-13 |
rat |
| Agnieszka A Zurek, Jieying Yu, Dian-Shi Wang, Sean C Haffey, Erica M Bridgwater, Antonello Penna, Irene Lecker, Gang Lei, Tom Chang, Eric W R Salter, Beverley A Orse. Sustained increase in α5GABAA receptor function impairs memory after anesthesia. The Journal of clinical investigation. vol 124. issue 12. 2015-07-08. PMID:25365226. |
the sustained increase in α5gaba(a)r activity impaired memory performance and synaptic plasticity in the hippocampus. |
2015-07-08 |
2023-08-13 |
Not clear |
| Yukitoshi Izumi, Charles F Zorumsk. Sensitivity of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to TCN 201 and TCN 213 in rat hippocampal slices. The Journal of pharmacology and experimental therapeutics. vol 352. issue 2. 2015-07-08. PMID:25413830. |
sensitivity of n-methyl-d-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to tcn 201 and tcn 213 in rat hippocampal slices. |
2015-07-08 |
2023-08-13 |
rat |
| Sijie Zhang, Denise Manahan-Vaugha. Place field stability requires the metabotropic glutamate receptor, mGlu5. Hippocampus. vol 24. issue 11. 2015-07-07. PMID:24910241. |
in the hippocampus, synaptic plasticity is one of the mechanisms by which spatial information may be represented. |
2015-07-07 |
2023-08-13 |
Not clear |
| Amina Chaalal, Roseline Poirier, David Blum, Brigitte Gillet, Pascale Le Blanc, Marie Basquin, Luc Buée, Serge Laroche, Valérie Enderli. PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments. Hippocampus. vol 24. issue 11. 2015-07-07. PMID:24978200. |
these modifications were associated with impaired spatial memory and reduced hippocampal expression of signaling molecules important for synaptic plasticity and memory, including neurogranin, camkii, erk, gsk3β, creb, and expression of the transcription factor egr1/zif268. |
2015-07-07 |
2023-08-13 |
rat |
| K An, J H Jung, A Y Jeong, H G Kim, S Y Jung, K Lee, H J Kim, S-J Kim, T-Y Jeong, Y Son, H-S Kim, J-H Ki. Neuritin can normalize neural deficits of Alzheimer's disease. Cell death & disease. vol 5. 2015-07-02. PMID:25393479. |
reductions in hippocampal neurite complexity and synaptic plasticity are believed to contribute to the progressive impairment in episodic memory and the mild cognitive decline that occur particularly in the early stages of alzheimer's disease (ad). |
2015-07-02 |
2023-08-13 |
mouse |
| K An, J H Jung, A Y Jeong, H G Kim, S Y Jung, K Lee, H J Kim, S-J Kim, T-Y Jeong, Y Son, H-S Kim, J-H Ki. Neuritin can normalize neural deficits of Alzheimer's disease. Cell death & disease. vol 5. 2015-07-02. PMID:25393479. |
we also showed that soluble recombinant neuritin, when chronically infused into the brains of tg2576 mice, normalized synaptic plasticity in acute hippocampal slices, leading to intact long-term potentiation. |
2015-07-02 |
2023-08-13 |
mouse |
| Dan Zhu, Chenchen Li, Andrew M Swanson, Rosa M Villalba, Jidong Guo, Zhaobin Zhang, Shannon Matheny, Tatsuro Murakami, Jason R Stephenson, Sarah Daniel, Masaki Fukata, Randy A Hall, Jeffrey J Olson, Gretchen N Neigh, Yoland Smith, Donald G Rainnie, Erwin G Van Mei. BAI1 regulates spatial learning and synaptic plasticity in the hippocampus. The Journal of clinical investigation. vol 125. issue 4. 2015-07-02. PMID:25751059. |
bai1 regulates spatial learning and synaptic plasticity in the hippocampus. |
2015-07-02 |
2023-08-13 |
mouse |
| Dan Zhu, Chenchen Li, Andrew M Swanson, Rosa M Villalba, Jidong Guo, Zhaobin Zhang, Shannon Matheny, Tatsuro Murakami, Jason R Stephenson, Sarah Daniel, Masaki Fukata, Randy A Hall, Jeffrey J Olson, Gretchen N Neigh, Yoland Smith, Donald G Rainnie, Erwin G Van Mei. BAI1 regulates spatial learning and synaptic plasticity in the hippocampus. The Journal of clinical investigation. vol 125. issue 4. 2015-07-02. PMID:25751059. |
restoration of psd-95 expression in hippocampal neurons in bai1-deficient mice by viral gene therapy was sufficient to compensate for bai1 loss and rescued deficits in synaptic plasticity. |
2015-07-02 |
2023-08-13 |
mouse |
| Julie Davies, Elena Zachariades, Karly-Rai Rogers-Broadway, Emmanouil Karteri. Elucidating the role of DEPTOR in Alzheimer's disease. International journal of molecular medicine. vol 34. issue 5. 2015-06-17. PMID:25119265. |
it has also been implicated in alzheimer's disease (ad) with neuronal cells and hippocampal slices of ad transgenic mice experiencing dysregulated mtor and synaptic plasticity in response to treatment with the toxic amyloid β (aβ(1-42)) peptide, which has been implicated in ad. |
2015-06-17 |
2023-08-13 |
mouse |
| Dan Xia, Hirotaka Watanabe, Bei Wu, Sang Hun Lee, Yan Li, Evgeny Tsvetkov, Vadim Y Bolshakov, Jie Shen, Raymond J Kellehe. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease. Neuron. vol 85. issue 5. 2015-06-15. PMID:25741723. |
furthermore, the l435f mutation impairs hippocampal synaptic plasticity and memory and causes age-dependent neurodegeneration in the aging cerebral cortex. |
2015-06-15 |
2023-08-13 |
mouse |
| Kiarash Riazi, Michael A Galic, Amanda C Kentner, Aylin Y Reid, Keith A Sharkey, Quentin J Pittma. Microglia-dependent alteration of glutamatergic synaptic transmission and plasticity in the hippocampus during peripheral inflammation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 12. 2015-06-15. PMID:25810524. |
chronic administration of the microglial/macrophage activation inhibitor minocycline to the inflamed animals both lowered the level of the cytokine tumor necrosis factor α in the hippocampus and completely abolished the effect of peripheral inflammation on the field potentials and synaptic plasticity (ltp and ltd). |
2015-06-15 |
2023-08-13 |
rat |
| Hardy Hagena, Denise Manahan-Vaugha. mGlu5 acts as a switch for opposing forms of synaptic plasticity at mossy fiber-CA3 and commissural associational-CA3 synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 12. 2015-06-15. PMID:25810529. |
given its crucial role in enabling persistent synaptic plasticity in other hippocampal subfields, we speculated that the metabotropic glutamate receptor mglu5 may regulate information encoding at mf and ac synapses. |
2015-06-15 |
2023-08-13 |
rat |
| Jerrel L Yake. Nicotinic ACh receptors in the hippocampal circuit; functional expression and role in synaptic plasticity. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:24860170. |
nicotinic ach receptors in the hippocampal circuit; functional expression and role in synaptic plasticity. |
2015-06-10 |
2023-08-13 |
Not clear |