| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abbasali Abbasnezhad, Parichehr Hayatdavoudi, Saeed Niazmand, Maryam Mahmoudabad. The effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in hippocampus of STZ-induced diabetic rats. Avicenna journal of phytomedicine. vol 5. issue 4. 2015-10-08. PMID:26445713. |
diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. |
2015-10-08 |
2023-08-13 |
rat |
| Min Jia, Wen-Xue Liu, He-Liang Sun, Yan-Qing Chang, Jiao-Jiao Yang, Mu-Huo Ji, Jian-Jun Yang, Chen-Zhuo Fen. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, attenuates postoperative cognitive dysfunction in aging mice. Frontiers in molecular neuroscience. vol 8. 2015-10-07. PMID:26441515. |
previous studies have shown that histone acetylation plays a key role in hippocampal synaptic plasticity and memory formation. |
2015-10-07 |
2023-08-13 |
mouse |
| Marta Portero-Tresserra, Nuria Del Olmo, Margarita Martí-Nicolovius, Gemma Guillazo-Blanch, Anna Vale-Martíne. D-cycloserine prevents relational memory deficits and suppression of long-term potentiation induced by scopolamine in the hippocampus. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 11. 2015-09-29. PMID:25453488. |
in the present study two experiments were conducted in rats to investigate whether dcs administered in the hippocampus may rescue relational memory deficits and improve deficient synaptic plasticity, both induced by an intracerebral injection of the muscarinic receptor antagonist scopolamine (scop). |
2015-09-29 |
2023-08-13 |
rat |
| Marta Portero-Tresserra, Nuria Del Olmo, Margarita Martí-Nicolovius, Gemma Guillazo-Blanch, Anna Vale-Martíne. D-cycloserine prevents relational memory deficits and suppression of long-term potentiation induced by scopolamine in the hippocampus. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 11. 2015-09-29. PMID:25453488. |
in experiment 2, we evaluated whether the perfusion of dcs in hippocampal slices may potentiate synaptic plasticity in ca1 synapses and thus recover scop-induced deficits in long-term potentiation (ltp). |
2015-09-29 |
2023-08-13 |
rat |
| Sergi Bayod, Paolo Felice, Pol Andrés, Paolo Rosa, Antoni Camins, Mercè Pallàs, Anna-Maria Canuda. Downregulation of canonical Wnt signaling in hippocampus of SAMP8 mice. Neurobiology of aging. vol 36. issue 2. 2015-09-28. PMID:25443287. |
in the adult brain, canonical wnt (wnt/β-catenin) signaling modulates neuronal function, hippocampal neurogenesis, and synaptic plasticity. |
2015-09-28 |
2023-08-13 |
mouse |
| Veronica Costa, Sebastian Lugert, Ravi Jagasi. Role of adult hippocampal neurogenesis in cognition in physiology and disease: pharmacological targets and biomarkers. Handbook of experimental pharmacology. vol 228. 2015-09-28. PMID:25977081. |
immature neurons in the adult brain exhibit an enhanced structural and synaptic plasticity during their maturation representing a unique population of neurons to mediate specific hippocampal function. |
2015-09-28 |
2023-08-13 |
human |
| Wei-Jye Lin, Cheng Jiang, Masato Sadahiro, Ozlem Bozdagi, Lucy Vulchanova, Cristina M Alberini, Stephen R Salto. VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 28. 2015-09-24. PMID:26180209. |
reduced vgf expression was found to impair learning-evoked rac1 induction and phosphorylation of the synaptic plasticity markers cofilin and synapsin in the adult mouse hippocampus. |
2015-09-24 |
2023-08-13 |
mouse |
| Brianne A Kent, Amy L Beynon, Amanda K E Hornsby, Pedro Bekinschtein, Timothy J Bussey, Jeffrey S Davies, Lisa M Saksid. The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation. Psychoneuroendocrinology. vol 51. 2015-09-21. PMID:25462915. |
there is accumulating evidence that the gut hormone ghrelin, an orexigenic peptide that is elevated during calorie restriction (cr) and known primarily for stimulating growth hormone release, has important extra-hypothalamic functions, such as enhancing synaptic plasticity and hippocampal neurogenesis. |
2015-09-21 |
2023-08-13 |
rat |
| Yuan-Jian Yang, Hai-Bo Chen, Bo Wei, Wei Wang, Ping-Liang Zhou, Jin-Qiong Zhan, Mao-Rong Hu, Kun Yan, Bin Hu, Bin Y. Cognitive decline is associated with reduced surface GluR1 expression in the hippocampus of aged rats. Neuroscience letters. vol 591. 2015-09-15. PMID:25697598. |
activity-dependent delivery of glur1-containing ampa receptor (ampars) plays an essential role in hippocampal synaptic plasticity, learning and memory. |
2015-09-15 |
2023-08-13 |
rat |
| S Grosser, J-O Hollnagel, K E Gilling, J C Bartsch, U Heinemann, J Beh. Gating of hippocampal output by β-adrenergic receptor activation in the pilocarpine model of epilepsy. Neuroscience. vol 286. 2015-09-14. PMID:25498224. |
to elucidate seizure-associated disturbances in the norepinephrine-dependent modulation of hippocampal output, we investigated the functional consequences of the β-ar-dependent synaptic plasticity at ca1-subiculum synapses for the transfer of hippocampal output to the parahippocampal region in the pilocarpine model of temporal lobe epilepsy. |
2015-09-14 |
2023-08-13 |
rat |
| Javier Gasulla, Daniel J Calv. Enhancement of tonic and phasic GABAergic currents following nitric oxide synthase inhibition in hippocampal CA1 pyramidal neurons. Neuroscience letters. vol 590. 2015-09-14. PMID:25636692. |
nitric oxide (no) is involved in synaptic plasticity in the hippocampus through different presynaptic and postsynaptic mechanisms that include the modulation of the gabaergic neurotransmission. |
2015-09-14 |
2023-08-13 |
mouse |
| Gangsoo Jung, Eun-Jung Kim, Ana Cicvaric, Sunetra Sase, Marion Gröger, Harald Höger, Fernando Jayson Sialana, Johannes Berger, Francisco J Monje, Gert Lube. Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus. Journal of neurochemistry. vol 134. issue 2. 2015-09-14. PMID:25865831. |
drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus. |
2015-09-14 |
2023-08-13 |
mouse |
| Gangsoo Jung, Eun-Jung Kim, Ana Cicvaric, Sunetra Sase, Marion Gröger, Harald Höger, Fernando Jayson Sialana, Johannes Berger, Francisco J Monje, Gert Lube. Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus. Journal of neurochemistry. vol 134. issue 2. 2015-09-14. PMID:25865831. |
electrophysiological studies further showed significant reduction in memory-related hippocampal synaptic plasticity upon drebrin depletion. |
2015-09-14 |
2023-08-13 |
mouse |
| Sandra Siegert, Jinsoo Seo, Ester J Kwon, Andrii Rudenko, Sukhee Cho, Wenyuan Wang, Zachary Flood, Anthony J Martorell, Maria Ericsson, Alison E Mungenast, Li-Huei Tsa. The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nature neuroscience. vol 18. issue 7. 2015-09-09. PMID:26005852. |
our data provide new insight into the mechanism by which mir-137 dysregulation can impair synaptic plasticity in the hippocampus. |
2015-09-09 |
2023-08-13 |
human |
| Meike Hick, Ulrike Herrmann, Sascha W Weyer, Jan-Philipp Mallm, Jakob-Andreas Tschäpe, Marianne Borgers, Marc Mercken, Fabian C Roth, Andreas Draguhn, Lutz Slomianka, David P Wolfer, Martin Korte, Ulrike C Mülle. Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity. Acta neuropathologica. vol 129. issue 1. 2015-08-31. PMID:25432317. |
strikingly, the impairment of ltp could be selectively rescued by acute application of exogenous recombinant appsα, but not appsβ, indicating a crucial role for appsα to support synaptic plasticity of mature hippocampal synapses on a rapid time scale. |
2015-08-31 |
2023-08-13 |
mouse |
| Hui-Yun Yang, Yang Liu, Jia-Cun Xie, Nan-Nan Liu, Xin Tia. Effects of repetitive transcranial magnetic stimulation on synaptic plasticity and apoptosis in vascular dementia rats. Behavioural brain research. vol 281. 2015-08-31. PMID:25541037. |
this study aims to determine whether low-frequency repetitive transcranial magnetic stimulation (rtms) protects pyramidal cells from apoptosis and promotes hippocampal synaptic plasticity in a vascular dementia (vad) rat model. |
2015-08-31 |
2023-08-13 |
rat |
| Hui-Yun Yang, Yang Liu, Jia-Cun Xie, Nan-Nan Liu, Xin Tia. Effects of repetitive transcranial magnetic stimulation on synaptic plasticity and apoptosis in vascular dementia rats. Behavioural brain research. vol 281. 2015-08-31. PMID:25541037. |
following establishment of a vad rat model using two-vessel occlusion (2vo), learning and memory were evaluated via the morris water maze (mwm), hippocampal ca1 neuron ultrastructure was examined via electron microscopy, and hippocampal synaptic plasticity was assessed by long-term potentiation (ltp). |
2015-08-31 |
2023-08-13 |
rat |
| b' Ana Djordjevic, Biljana Bursa\\xc4\\x87, Nata\\xc5\\xa1a Veli\\xc4\\x8dkovi\\xc4\\x87, Ana Vasiljevi\\xc4\\x87, Gordana Mati\\xc4\\x8. The impact of different fructose loads on insulin sensitivity, inflammation, and PSA-NCAM-mediated plasticity in the hippocampus of fructose-fed male rats. Nutritional neuroscience. vol 18. issue 2. 2015-08-28. PMID:24257416.' |
we hypothesized that long-term access to fructose (10% and 60% solutions over a period of 9 weeks) affects insulin sensitivity, hippocampal inflammation, and synaptic plasticity in male wistar rats. |
2015-08-28 |
2023-08-12 |
rat |
| Peter Jedlicka, Matej Vnencak, Dilja D Krueger, Tassilo Jungenitz, Nils Brose, Stephan W Schwarzache. Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain structure & function. vol 220. issue 1. 2015-08-28. PMID:25713840. |
taken together, we provide first evidence that nl1 is essential for normal excitatory transmission and long-term synaptic plasticity in the hippocampus of intact animals. |
2015-08-28 |
2023-08-13 |
mouse |
| Cristiano Mendes-da-Silva, Simone Ferreira Lemes, Tanyara da Silva Baliani, Milena Diorio Versutti, Marcio Alberto Torson. Increased expression of Hes5 protein in Notch signaling pathway in the hippocampus of mice offspring of dams fed a high-fat diet during pregnancy and suckling. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 40. 2015-08-26. PMID:25450527. |
maternal high-fat diet (hfd) impairs hippocampal development of offspring promoting decreased proliferation of neural progenitors, in neuronal differentiation, in dendritic spine density and synaptic plasticity reducing neurogenic capacity. |
2015-08-26 |
2023-08-13 |
mouse |