| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David Higgins, Michael Graupner, Nicolas Brune. Memory maintenance in synapses with calcium-based plasticity in the presence of background activity. PLoS computational biology. vol 10. issue 10. 2015-11-16. PMID:25275319. |
in this paper, we investigate the time scales of memory maintenance in a calcium-based synaptic plasticity model that has been shown recently to be able to fit different experimental data-sets from hippocampal and neocortical preparations. |
2015-11-16 |
2023-08-13 |
Not clear |
| Somi Kim, TaeHyun Kim, Hye-Ryeon Lee, Young-Yun Kong, Bong-Kiun Kaan. Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 19. issue 6. 2015-11-11. PMID:26557018. |
accordingly, we found impaired hippocampal synaptic plasticity in mib2 knock-out (ko) mice; however, basal synaptic transmission did not change at the schaffer collateral-ca1 synapses. |
2015-11-11 |
2023-08-13 |
mouse |
| Sandra Dieni, Sigrun Nestel, Mirjam Sibbe, Michael Frotscher, Sabine Hellwi. Distinct synaptic and neurochemical changes to the granule cell-CA3 projection in Bassoon mutant mice. Frontiers in synaptic neuroscience. vol 7. 2015-11-11. PMID:26557085. |
to this end, we used a mutant mouse model harboring a mutated form of the presynaptic scaffolding protein bassoon (bsn), which is phenotypically characterized by: (i) spontaneous generalized epileptic seizure activity, representing a chronically-imbalanced neuronal network; and (ii) a dramatic increase in hippocampal brain-derived neurotrophic factor (bdnf) protein concentration, a key player in synaptic plasticity. |
2015-11-11 |
2023-08-13 |
mouse |
| Manuella P Kaster, Nuno J Machado, Henrique B Silva, Ana Nunes, Ana Paula Ardais, Magda Santana, Younis Baqi, Christa E Müller, Ana Lúcia S Rodrigues, Lisiane O Porciúncula, Jiang Fan Chen, Ângelo R Tomé, Paula Agostinho, Paula M Canas, Rodrigo A Cunh. Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 25. 2015-11-10. PMID:26056314. |
these behavioral changes were accompanied by synaptic alterations, typified by a decrease in synaptic plasticity and a reduced density of synaptic proteins (synaptosomal-associated protein 25, syntaxin, and vesicular glutamate transporter type 1), together with an increased density of a2ar in glutamatergic terminals in the hippocampus. |
2015-11-10 |
2023-08-13 |
mouse |
| Jimcy Platholi, Karl F Herold, Hugh C Hemmings, Shelley Halpai. Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism. PloS one. vol 9. issue 7. 2015-11-09. PMID:25068870. |
these reversible alterations in dendritic spine structure have important implications for acute anesthetic effects on excitatory synaptic transmission and synaptic stability in the hippocampus, a locus for anesthetic-induced amnesia, and have important implications for anesthetic effects on synaptic plasticity. |
2015-11-09 |
2023-08-13 |
rat |
| Edward G Meloni, Timothy E Gillis, Jasmine Manoukian, Marc J Kaufma. Xenon impairs reconsolidation of fear memories in a rat model of post-traumatic stress disorder (PTSD). PloS one. vol 9. issue 8. 2015-11-06. PMID:25162644. |
xe inhibits glutamatergic n-methyl-d-aspartate (nmda) receptors involved in learning and memory and can affect synaptic plasticity in the amygdala and hippocampus, two brain areas known to play a role in fear conditioning models of post-traumatic stress disorder (ptsd). |
2015-11-06 |
2023-08-13 |
rat |
| Eric S Sweet, Bernadette Saunier-Rebori, Zhenyu Yue, Robert D Blitze. The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 32. 2015-11-05. PMID:26269629. |
the parkinson's disease-associated mutation lrrk2-g2019s impairs synaptic plasticity in mouse hippocampus. |
2015-11-05 |
2023-08-13 |
mouse |
| Alina Savotchenko, Arthur Romanov, Dmytro Isaev, Oleksandr Maximyuk, Vadym Sydorenko, Gregory L Holmes, Elena Isaev. Neuraminidase inhibition primes short-term depression and suppresses long-term potentiation of synaptic transmission in the rat hippocampus. Neural plasticity. vol 2015. 2015-11-04. PMID:25802763. |
using combined rat entorhinal cortex/hippocampal slices and a specific inhibitor of neu, 2-deoxy-2,3-dehydro-n-acetylneuraminic acid (nadna), we examined the effect of downregulation of neu activity on different forms of synaptic plasticity in the hippocampal ca3-to-ca1 network. |
2015-11-04 |
2023-08-13 |
rat |
| Marco Mainardi, Salvatore Fusco, Claudio Grass. Modulation of hippocampal neural plasticity by glucose-related signaling. Neural plasticity. vol 2015. 2015-11-04. PMID:25977822. |
indeed, all these factors affect fundamental hippocampal properties including synaptic plasticity (i.e., synapse potentiation and depression), structural plasticity (i.e., dynamics of dendritic spines), and adult neurogenesis, thus leading to modifications in cognitive performance. |
2015-11-04 |
2023-08-13 |
Not clear |
| Vasiliki Kyrargyri, Germán Vega-Flores, Agnès Gruart, José M Delgado-García, Lesley Prober. Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice. Glia. vol 63. issue 4. 2015-10-29. PMID:25297800. |
our results show that microglia, through ikkβ and therefore nf-κb activity, regulate hippocampal synaptic plasticity and that both microglia and neurons, through ikkβ, are necessary for animals to modify hippocampus-driven behavior during associative learning. |
2015-10-29 |
2023-08-13 |
mouse |
| Anurag Pandey, Sujit Kumar Sikda. Depression biased non-Hebbian spike-timing-dependent synaptic plasticity in the rat subiculum. The Journal of physiology. vol 592. issue 16. 2015-10-26. PMID:24907304. |
thus the mechanism of synaptic plasticity may vary within a hippocampal subfield depending on the postsynaptic neuron involved. |
2015-10-26 |
2023-08-13 |
rat |
| K M Fric. Epigenetics, oestradiol and hippocampal memory consolidation. Journal of neuroendocrinology. vol 25. issue 11. 2015-10-23. PMID:24028406. |
epigenetic alterations of histone proteins and dna are essential for hippocampal synaptic plasticity and cognitive function, and contribute to the aetiology of psychiatric disorders and neurodegenerative diseases. |
2015-10-23 |
2023-08-12 |
mouse |
| Marlene J Végh, Antonio Rausell, Maarten Loos, Céline M Heldring, Wiktor Jurkowski, Pim van Nierop, Iryna Paliukhovich, Ka Wan Li, Antonio del Sol, August B Smit, Sabine Spijker, Ronald E van Kestere. Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline. Molecular & cellular proteomics : MCP. vol 13. issue 11. 2015-10-23. PMID:25044018. |
this was confirmed by immunoblotting and histochemical analysis, which indicated that the increased levels of hippocampal extracellular matrix might limit synaptic plasticity as a potential cause of age-related cognitive decline. |
2015-10-23 |
2023-08-13 |
mouse |
| Tariq Ahmed, Ann Van der Jeugd, David Blum, Marie-Christine Galas, Rudi D'Hooge, Luc Buee, Detlef Balschu. Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion. Neurobiology of aging. vol 35. issue 11. 2015-10-19. PMID:24913895. |
cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion. |
2015-10-19 |
2023-08-13 |
mouse |
| Robert Alan Mans, Brian A Warmus, Caroline C Smith, Lori L McMaho. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. Journal of neurophysiology. vol 112. issue 10. 2015-10-19. PMID:25143547. |
studies in humans and rodents support a role for muscarinic ach receptor (machr) and nicotinic achr in learning and memory, and both regulate hippocampal synaptic plasticity using complex and often times opposing mechanisms. |
2015-10-19 |
2023-08-13 |
rat |
| Padmanabh Singh, Arpita Konar, Ashish Kumar, Sweta Srivas, Mahendra K Thaku. Hippocampal chromatin-modifying enzymes are pivotal for scopolamine-induced synaptic plasticity gene expression changes and memory impairment. Journal of neurochemistry. vol 134. issue 4. 2015-10-19. PMID:25982413. |
hippocampal chromatin-modifying enzymes are pivotal for scopolamine-induced synaptic plasticity gene expression changes and memory impairment. |
2015-10-19 |
2023-08-13 |
Not clear |
| Shijun Yan, Zhi Li, Hang Li, Ottavio Arancio, Wensheng Zhan. Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. Scientific reports. vol 4. 2015-10-16. PMID:25213453. |
we assessed the effects of ntr1 on neuronal excitability, membrane ion channel activity, and synaptic plasticity in acute hippocampal slices by combining electrophysiological extracellular and intracellular recording techniques. |
2015-10-16 |
2023-08-13 |
mouse |
| Cristina Vasuta, Julien Artinian, Isabel Laplante, Sarah Hébert-Seropian, Karim Elayoubi, Jean-Claude Lacaill. Metaplastic Regulation of CA1 Schaffer Collateral Pathway Plasticity by Hebbian MGluR1a-Mediated Plasticity at Excitatory Synapses onto Somatostatin-Expressing Interneurons eNeuro. vol 2. issue 4. 2015-10-14. PMID:26464997. |
our findings provide new insights on the contribution of interneuron synaptic plasticity in the regulation of the hippocampal network activity and mnemonic processes. |
2015-10-14 |
2023-08-13 |
mouse |
| Daniel G McHail, Theodore C Duma. Multiple forms of metaplasticity at a single hippocampal synapse during late postnatal development. Developmental cognitive neuroscience. vol 12. 2015-10-12. PMID:25752732. |
this review paper describes three late postnatal modifications to synaptic plasticity induction in the hippocampus and attempts to relate these metaplastic changes to developmental alterations in hippocampal network activity and the maturation of contextual learning. |
2015-10-12 |
2023-08-13 |
rat |
| Shaoli Wang, Jingyun Zhang, Tao Sheng, Wei Lu, Dengshun Mia. Hippocampal ischemia causes deficits in local field potential and synaptic plasticity. Journal of biomedical research. vol 29. issue 5. 2015-10-08. PMID:26445570. |
hippocampal ischemia causes deficits in local field potential and synaptic plasticity. |
2015-10-08 |
2023-08-13 |
Not clear |