| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dhiraj Kumar, M K Thaku. Age-related expression of Neurexin1 and Neuroligin3 is correlated with presynaptic density in the cerebral cortex and hippocampus of male mice. Age (Dordrecht, Netherlands). vol 37. issue 2. 2016-02-11. PMID:25693924. |
thus, these findings showed that nrxn1 and nlgn3 are differentially expressed in cerebral cortex and hippocampus which might be responsible for alterations in synaptic plasticity during aging. |
2016-02-11 |
2023-08-13 |
mouse |
| Lida Tahmasebi, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Iraj Salehi, Ali Nikkha. The interactive role of cannabinoid and vanilloid systems in hippocampal synaptic plasticity in rats. European journal of pharmacology. vol 757. 2016-02-04. PMID:25843413. |
the interactive role of cannabinoid and vanilloid systems in hippocampal synaptic plasticity in rats. |
2016-02-04 |
2023-08-13 |
rat |
| Lida Tahmasebi, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Iraj Salehi, Ali Nikkha. The interactive role of cannabinoid and vanilloid systems in hippocampal synaptic plasticity in rats. European journal of pharmacology. vol 757. 2016-02-04. PMID:25843413. |
the activation of the vanillioid system has also been shown to mediate synaptic plasticity in the hippocampus. |
2016-02-04 |
2023-08-13 |
rat |
| Claudia A Grillo, Gerardo G Piroli, Robert C Lawrence, Shayna A Wrighten, Adrienne J Green, Steven P Wilson, Randall R Sakai, Sandra J Kelly, Marlene A Wilson, David D Mott, Lawrence P Reaga. Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity. Diabetes. vol 64. issue 11. 2016-02-02. PMID:26216852. |
hippocampal insulin resistance impairs spatial learning and synaptic plasticity. |
2016-02-02 |
2023-08-13 |
rat |
| Annelies Laeremans, Victor Sabanov, Tariq Ahmed, Julie Nys, Babs Van de Plas, Kasper Vinken, Daniel G Woolley, Ilse Gantois, Rudi D'Hooge, Lutgarde Arckens, Detlef Balschu. Distinct and simultaneously active plasticity mechanisms in mouse hippocampus during different phases of Morris water maze training. Brain structure & function. vol 220. issue 3. 2016-01-27. PMID:24562414. |
when intrinsic 'somatic' and synaptic plasticity in the ca1-region of hippocampal slices were examined, we found that early learning promotes intrinsic neuronal plasticity as manifested by a reduction of spike frequency adaptation and postburst afterhyperpolarization. |
2016-01-27 |
2023-08-12 |
mouse |
| Huy-Binh Nguyen, Rosemary C Bagot, Josie Diorio, Tak Pan Wong, Michael J Meane. Maternal care differentially affects neuronal excitability and synaptic plasticity in the dorsal and ventral hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 7. 2016-01-25. PMID:25598429. |
maternal care differentially affects neuronal excitability and synaptic plasticity in the dorsal and ventral hippocampus. |
2016-01-25 |
2023-08-13 |
rat |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
in the hippocampus, brain-derived neurotrophic factor (bdnf) plays roles in neurogenesis, neuronal survival, neuronal differentiation, and synaptic plasticity. |
2016-01-22 |
2023-08-13 |
mouse |
| John D Graef, Kimberly Newberry, Amy Newton, Rick Pieschl, Eric Shields, Fu-Ni Luan, Jean Simmermacher, David Luchetti, Eric Schaeffer, Yu-Wen Li, Laszlo Kiss, Linda J Bristo. Effect of acute NR2B antagonist treatment on long-term potentiation in the rat hippocampus. Brain research. vol 1609. 2016-01-20. PMID:25796435. |
ketamine administration in patients with treatment-resistant depression (trd) is thought to result from enhanced synaptic plasticity in cortical and hippocampal circuits. |
2016-01-20 |
2023-08-13 |
rat |
| John D Graef, Kimberly Newberry, Amy Newton, Rick Pieschl, Eric Shields, Fu-Ni Luan, Jean Simmermacher, David Luchetti, Eric Schaeffer, Yu-Wen Li, Laszlo Kiss, Linda J Bristo. Effect of acute NR2B antagonist treatment on long-term potentiation in the rat hippocampus. Brain research. vol 1609. 2016-01-20. PMID:25796435. |
using extracellular field recordings in rat hippocampal slices, we show that a single dose of the non-selective nmda receptor antagonist ketamine or cp-101,606, a selective antagonist of the nr2b subunit of the nmda receptor, enhances hippocampal synaptic plasticity induced with high frequency stimulation (hfs) 24h after dosing - a time at which plasma concentrations of the drug are no longer detectable in the animal. |
2016-01-20 |
2023-08-13 |
rat |
| Mengying Liu, Xuhong Huangfu, Yangang Zhao, Dongmei Zhang, Jiqiang Zhan. Steroid receptor coactivator-1 mediates letrozole induced downregulation of postsynaptic protein PSD-95 in the hippocampus of adult female rats. The Journal of steroid biochemistry and molecular biology. vol 154. 2016-01-19. PMID:26223010. |
hippocampus local estrogen which is converted from androgen that catalyzed by aromatase has been shown to play important roles in the regulation of learning and memory as well as cognition through action on synaptic plasticity, but the underlying mechanisms are poorly understood. |
2016-01-19 |
2023-08-13 |
rat |
| Mengying Liu, Xuhong Huangfu, Yangang Zhao, Dongmei Zhang, Jiqiang Zhan. Steroid receptor coactivator-1 mediates letrozole induced downregulation of postsynaptic protein PSD-95 in the hippocampus of adult female rats. The Journal of steroid biochemistry and molecular biology. vol 154. 2016-01-19. PMID:26223010. |
taking together, these results provided the first evidence that src-1 mediated endogenous estrogen regulation of hippocampal synaptic plasticity by targeting the expression of synaptic protein psd-95. |
2016-01-19 |
2023-08-13 |
rat |
| Jing Gao, Xiaochen Zhang, Mei Yu, Guogang Ren, Zhuo Yan. Cognitive deficits induced by multi-walled carbon nanotubes via the autophagic pathway. Toxicology. vol 337. 2016-01-19. PMID:26327526. |
in this study, we investigated the neurotoxic effects of mwcnts on hippocampal synaptic plasticity and spatial cognition in rats. |
2016-01-19 |
2023-08-13 |
rat |
| Jing Gao, Xiaochen Zhang, Mei Yu, Guogang Ren, Zhuo Yan. Cognitive deficits induced by multi-walled carbon nanotubes via the autophagic pathway. Toxicology. vol 337. 2016-01-19. PMID:26327526. |
then, we used an inhibitor of autophagy called chloroquine (cq) to examine whether autophagy plays an important role in hippocampal synaptic plasticity, since this was damaged by mwcnts. |
2016-01-19 |
2023-08-13 |
rat |
| Kim Doré, Simon Labrecque, Christian Tardif, Paul De Koninc. FRET-FLIM investigation of PSD95-NMDA receptor interaction in dendritic spines; control by calpain, CaMKII and Src family kinase. PloS one. vol 9. issue 11. 2016-01-15. PMID:25393018. |
we used a fret-flim approach in developing cultured rat hippocampal neurons expressing fluorescently tagged nmda receptor (nmdar) and psd95, two essential proteins in synaptic plasticity, to examine the regulation of their interaction. |
2016-01-15 |
2023-08-13 |
rat |
| Henry Silver, Nina Mandiuk, Reef Einoch, Ehud Susser, Lena Danovich, Warren Bilker, Moussa Youdim, Orly Weinre. Improvement in verbal memory following SSRI augmentation of antipsychotic treatment is associated with changes in the expression of mRNA encoding for the GABA-A receptor and BDNF in PMC of schizophrenic patients. International clinical psychopharmacology. vol 30. issue 3. 2016-01-15. PMID:25756551. |
it is postulated that the mechanism involves enhanced gaba-a receptor/bdnf-dependent synaptic plasticity in the hippocampus. |
2016-01-15 |
2023-08-13 |
Not clear |
| Hua Zhang, Jie Liu, Suya Sun, Ekaterina Pchitskaya, Elena Popugaeva, Ilya Bezprozvann. Calcium signaling, excitability, and synaptic plasticity defects in a mouse model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 45. issue 2. 2016-01-14. PMID:25589721. |
to understand the basis for this phenomenon, in the present study we analyzed structural synaptic plasticity in hippocampal cultures from wild type (wt) and ki mice. |
2016-01-14 |
2023-08-13 |
mouse |
| Kihoon Han, Hogmei Chen, Vincenzo A Gennarino, Ronald Richman, Hui-Chen Lu, Huda Y Zoghb. Fragile X-like behaviors and abnormal cortical dendritic spines in cytoplasmic FMR1-interacting protein 2-mutant mice. Human molecular genetics. vol 24. issue 7. 2016-01-13. PMID:25432536. |
synaptic plasticity and dendritic spines were normal in cyfip2(+/-) hippocampus. |
2016-01-13 |
2023-08-13 |
mouse |
| Shuxi Liu, Yue Wang, Paul F Worley, Mark P Mattson, Nicholas Gaian. The canonical Notch pathway effector RBP-J regulates neuronal plasticity and expression of GABA transporters in hippocampal networks. Hippocampus. vol 25. issue 5. 2016-01-13. PMID:25515406. |
our results reveal an essential role for canonical notch/rbp-j signaling in hippocampal synaptic plasticity and suggest that role, at least in part, is mediated by the regulation of gabaergic signaling. |
2016-01-13 |
2023-08-13 |
Not clear |
| Elisaveta E Genrikhs, Elena V Stelmashook, Olga V Popova, Nadezhda A Kapay, Galina A Korshunova, Natalya V Sumbatyan, Vladimir G Skrebitsky, Vladimir P Skulachev, Nickolay K Isae. Mitochondria-targeted antioxidant SkQT1 decreases trauma-induced neurological deficit in rat and prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices. Journal of drug targeting. vol 23. issue 4. 2016-01-13. PMID:25585580. |
this study assesses a protective effect of a mitochondria-targeted antioxidant skqt1 (a mixture of 10-(6'-toluquinonyl) decyltriphenylphosphonium and 10-(5'-toluquinonyl) decyltriphenylphosphonium in proportion of 1.4:1), using an open focal trauma model of the rat brain sensorimotor cortex and a model of amyloid-beta1-42 (abeta)-induced impairment of hippocampal long-term potentiation (ltp), a kind of synaptic plasticity associated with learning and memory. |
2016-01-13 |
2023-08-13 |
rat |
| Andrew L Eagle, Paula A Gajewski, Miyoung Yang, Megan E Kechner, Basma S Al Masraf, Pamela J Kennedy, Hongbing Wang, Michelle S Mazei-Robison, Alfred J Robiso. Experience-Dependent Induction of Hippocampal ΔFosB Controls Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 40. 2016-01-13. PMID:26446228. |
the hippocampus (hpc) is known to play an important role in learning, a process dependent on synaptic plasticity; however, the molecular mechanisms underlying this are poorly understood. |
2016-01-13 |
2023-08-13 |
mouse |