| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hirobumi Tada, Mayu Koide, Wakana Ara, Yusuke Shibata, Toshiya Funabashi, Kumiko Suyama, Takahisa Goto, Takuya Takahash. Estrous Cycle-Dependent Phasic Changes in the Stoichiometry of Hippocampal Synaptic AMPA Receptors in Rats. PloS one. vol 10. issue 6. 2016-03-28. PMID:26121335. |
these results suggest that high estrogen levels prevent the ia learning-induced delivery of cp-ampars into hippocampal ca3-ca1 synapses and limit synaptic plasticity after ia task, thus preventing the acquisition of additional learning. |
2016-03-28 |
2023-08-13 |
rat |
| Níal P Harte, Igor Klyubin, Eoin K McCarthy, Soyoung Min, Sarah Ann Garrahy, Yongjing Xie, Gavin P Davey, John J Boland, Michael J Rowan, K Hun Mo. Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms. The Journal of biological chemistry. vol 290. issue 47. 2016-03-27. PMID:26221033. |
we have also shown that oligomers but not sonicated mature fibrils inhibit hippocampal long term potentiation, a form of synaptic plasticity implicated in learning and memory, in vivo. |
2016-03-27 |
2023-08-13 |
rat |
| Andras Kern, Maria Mavrikaki, Celine Ullrich, Rosie Albarran-Zeckler, Alicia Faruzzi Brantley, Roy G Smit. Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor. Cell. vol 163. issue 5. 2016-03-27. PMID:26590421. |
activation by a drd1 agonist produced non-canonical signal transduction via gαq-plc-ip3-ca(2+) at the expense of canonical drd1 gαs camp signaling to result in camkii activation, glutamate receptor exocytosis, synaptic reorganization, and expression of early markers of hippocampal synaptic plasticity. |
2016-03-27 |
2023-08-13 |
mouse |
| Andras Kern, Maria Mavrikaki, Celine Ullrich, Rosie Albarran-Zeckler, Alicia Faruzzi Brantley, Roy G Smit. Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor. Cell. vol 163. issue 5. 2016-03-27. PMID:26590421. |
our findings identify a previously unrecognized mechanism essential for drd1 initiation of hippocampal synaptic plasticity that is dependent on ghsr1a, and independent of camp signaling. |
2016-03-27 |
2023-08-13 |
mouse |
| Gemma McGregor, Yasaman Malekizadeh, Jenni Harve. Minireview: Food for thought: regulation of synaptic function by metabolic hormones. Molecular endocrinology (Baltimore, Md.). vol 29. issue 1. 2016-03-24. PMID:25470238. |
indeed, it has been demonstrated that both leptin and insulin markedly influence key cellular events that underlie hippocampal learning and memory including activity-dependent synaptic plasticity and the trafficking of glutamate receptors to and away from hippocampal synapses. |
2016-03-24 |
2023-08-13 |
Not clear |
| Bettina Drisaldi, Luca Colnaghi, Luana Fioriti, Nishta Rao, Cory Myers, Anna M Snyder, Daniel J Metzger, Jenna Tarasoff, Edward Konstantinov, Paul E Fraser, James L Manley, Eric R Kande. SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3. Cell reports. vol 11. issue 11. 2016-03-24. PMID:26074071. |
the prion-like cytoplasmic polyadenylation element-binding protein 3 (cpeb3) regulates the translation of several mrnas important for long-term synaptic plasticity in the hippocampus. |
2016-03-24 |
2023-08-13 |
Not clear |
| X Han, W Shao, Z Liu, S Fan, J Yu, J Chen, R Qiao, J Zhou, P Xi. iTRAQ-based quantitative analysis of hippocampal postsynaptic density-associated proteins in a rat chronic mild stress model of depression. Neuroscience. vol 298. 2016-03-21. PMID:25862978. |
in sum, these findings provide novel insights into the contribution of psd-associated proteins to stress susceptibility and further advance our understanding of the role of hippocampal synaptic plasticity in mdd. |
2016-03-21 |
2023-08-13 |
rat |
| Somayeh Zargooshnia, Siamak Shahidi, Fatemeh Ghahremanitamadon, Ali Nikkhah, Mehdi Mehdizadeh, Sara Soleimani As. The protective effect of Borago Officinalis extract on amyloid β (25-35)-induced long term potentiation disruption in the dentate gyrus of male rats. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:25060965. |
this data suggest that aβ (25-35) can effectively inhibit ltp in the granular cells of the dg in hippocampus, and borage supplementation reverse the synaptic plasticity in dg following aβ treatment and that borage consumption may lead to an improvement of ad-induced cognitive dysfunction. |
2016-03-17 |
2023-08-13 |
rat |
| Daniela Puzzo, Antonella Bizzoca, Carla Loreto, Chiara A Guida, Walter Gulisano, Giuseppina Frasca, Maria Bellomo, Sergio Castorina, Gianfranco Gennarini, Agostino Palmer. Role of F3/contactin expression profile in synaptic plasticity and memory in aged mice. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25659859. |
we have recently shown that overexpression of the f3/contactin adhesive glycoprotein (also known as contactin-1) promotes neurogenesis in adult hippocampus, which correlates with improved synaptic plasticity and memory. |
2016-03-17 |
2023-08-13 |
mouse |
| Daniela Puzzo, Antonella Bizzoca, Carla Loreto, Chiara A Guida, Walter Gulisano, Giuseppina Frasca, Maria Bellomo, Sergio Castorina, Gianfranco Gennarini, Agostino Palmer. Role of F3/contactin expression profile in synaptic plasticity and memory in aged mice. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25659859. |
our data confirm that f3/contactin plays a role in hippocampal synaptic plasticity and memory also in aged mice, suggesting that it acts on molecular pathways related to apoptosis and amyloid-beta production. |
2016-03-17 |
2023-08-13 |
mouse |
| Ewelina Kurowska, Irena Majkutewic. [The interleukin-10 in the central nervous system]. Postepy higieny i medycyny doswiadczalnej (Online). vol 69. 2016-03-17. PMID:26270515. |
involvement of il-10 in neuroprotection, neurogenesis, regulation of the stress response and hippocampal synaptic plasticity connected with learning and memory is suggested. |
2016-03-17 |
2023-08-13 |
Not clear |
| Susan L Patterso. Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity. Neuropharmacology. vol 96. issue Pt A. 2016-03-16. PMID:25549562. |
this review will focus on the impact of dysregulated production of il-1β on hippocampus dependent-memory systems and associated synaptic plasticity processes. |
2016-03-16 |
2023-08-13 |
Not clear |
| Hye Jin Park, Seungheon Lee, Ji Wook Jung, Byeong C Kim, Jong Hoon Ryu, Dong Hyun Ki. Glucocorticoid- and long-term stress-induced aberrant synaptic plasticity are mediated by activation of the glucocorticoid receptor. Archives of pharmacal research. vol 38. issue 6. 2016-03-08. PMID:25564339. |
these results suggest that corticosterone and long-term stress induce aberrant synaptic plasticity, memory impairment, and reduction in the hippocampal bdnf level through gr activation. |
2016-03-08 |
2023-08-13 |
rat |
| Kathryn A Haynes, Thuy K Smith, Collin J Preston, Ashok N Hegd. Proteasome inhibition augments new protein accumulation early in long-term synaptic plasticity and rescues adverse Aβ effects on protein synthesis. ACS chemical neuroscience. vol 6. issue 5. 2016-03-07. PMID:25775404. |
in this study, we tested the effect of proteasome inhibition on protein synthesis using a chemically induced long-lasting synaptic plasticity (cltp) in the murine hippocampus as a model system. |
2016-03-07 |
2023-08-13 |
Not clear |
| Masoud Soheili, Mostafa Rezaei Tavirani, Mahmoud Salam. Lavandula angustifolia extract improves deteriorated synaptic plasticity in an animal model of Alzheimer's disease. Iranian journal of basic medical sciences. vol 18. issue 11. 2016-03-07. PMID:26949505. |
long-term potentiation (ltp), an experimental form of synaptic plasticity, is intensively examined in hippocampus. |
2016-03-07 |
2023-08-13 |
Not clear |
| Wen-Lin Chen, Bin Xie, Chong Zhang, Kang-Li Xu, Ying-Ying Niu, Xiao-Qing Tang, Ping Zhang, Wei Zou, Bi Hu, Ying Tia. Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in behavioral models of depression and anxiety. Behavioural pharmacology. vol 24. issue 7. 2016-03-03. PMID:23974423. |
it has been reported that hydrogen sulfide (h2s), the third gaseous transmitter, facilitates the induction of hippocampal long-term potentiation and augments synaptic neurotransmission, involved in the regulation of synaptic plasticity. |
2016-03-03 |
2023-08-12 |
mouse |
| Huili Han, Yan Peng, Zhifang Don. D-Serine rescues the deficits of hippocampal long-term potentiation and learning and memory induced by sodium fluoroacetate. Pharmacology, biochemistry, and behavior. vol 133. 2016-03-03. PMID:25843400. |
together, these results suggest that astrocytic d-serine may be essential for hippocampal synaptic plasticity and memory, and that alteration of its levels may be relevant to the induction and potentially treatment of psychiatric and neurological disorders. |
2016-03-03 |
2023-08-13 |
Not clear |
| Ji-Wei Tan, Ting-Ting Duan, Qi-Xin Zhou, Ze-Yang Ding, Liang Jing, Jun Cao, Li-Ping Wang, Rong-Rong Mao, Lin X. Impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure. Addiction biology. vol 20. issue 4. 2016-02-29. PMID:24903743. |
impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure. |
2016-02-29 |
2023-08-13 |
rat |
| Ji-Wei Tan, Ting-Ting Duan, Qi-Xin Zhou, Ze-Yang Ding, Liang Jing, Jun Cao, Li-Ping Wang, Rong-Rong Mao, Lin X. Impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure. Addiction biology. vol 20. issue 4. 2016-02-29. PMID:24903743. |
these alterations in pm rats were mirrored by abnormalities in synaptic plasticity in the schaffer collateral-ca1 synapses of the hippocampus in vivo. |
2016-02-29 |
2023-08-13 |
rat |
| Moshe Gross, Anton Sheinin, Elimelech Nesher, Tatiana Tikhonov, Danny Baranes, Albert Pinhasov, Izhak Michaelevsk. Early onset of cognitive impairment is associated with altered synaptic plasticity and enhanced hippocampal GluA1 expression in a mouse model of depression. Neurobiology of aging. vol 36. issue 5. 2016-02-29. PMID:25796132. |
early onset of cognitive impairment is associated with altered synaptic plasticity and enhanced hippocampal glua1 expression in a mouse model of depression. |
2016-02-29 |
2023-08-13 |
mouse |