| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eri Kawai, Nobuto Shibata, Tomoyuki Nagata, Shunichiro Shinagawa, Kenji Tagai, Kenji Tgai, Tohru Ohnuma, Hiromi Shimazaki, Aiko Toda, Koji Kasanuki, Toshiki Takayama, Ayako Suzuki, Kazuhiko Nakayama, Hisashi Yamada, Heii Ara. Genetic Association Between KIBRA Polymorphism and Alzheimer's Disease with in a Japanese Population. Neuromolecular medicine. vol 17. issue 2. 2016-04-21. PMID:25800888. |
kibra plays an important role in synaptic plasticity in human hippocampus related to cognitive function. |
2016-04-21 |
2023-08-13 |
human |
| Emanuela Santini, Kathryn L Turner, Akila B Ramaraj, Michael P Murphy, Eric Klann, Hanoch Kaphza. Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 49. 2016-04-20. PMID:26658871. |
in addition, we found that mitoq rescued impairments in hippocampal synaptic plasticity and deficits in contextual fear memory exhibited by as model mice. |
2016-04-20 |
2023-08-13 |
mouse |
| Xike Qin, Yongjun Jiang, Yiu Chung Tse, Yunling Wang, Tak Pan Wong, Hemant K Paude. Early Growth Response 1 (Egr-1) Regulates N-Methyl-d-aspartate Receptor (NMDAR)-dependent Transcription of PSD-95 and α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor (AMPAR) Trafficking in Hippocampal Primary Neurons. The Journal of biological chemistry. vol 290. issue 49. 2016-04-19. PMID:26475861. |
the n-methyl-d-aspartate receptor (nmdar) controls synaptic plasticity and memory function and is one of the major inducers of transcription factor egr-1 in the hippocampus. |
2016-04-19 |
2023-08-13 |
mouse |
| Xike Qin, Yongjun Jiang, Yiu Chung Tse, Yunling Wang, Tak Pan Wong, Hemant K Paude. Early Growth Response 1 (Egr-1) Regulates N-Methyl-d-aspartate Receptor (NMDAR)-dependent Transcription of PSD-95 and α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor (AMPAR) Trafficking in Hippocampal Primary Neurons. The Journal of biological chemistry. vol 290. issue 49. 2016-04-19. PMID:26475861. |
here, we show that the hippocampus of mice lacking egr-1 displays electrophysiology properties and ultrastructure that are similar to mice overexpressing psd-95, a major scaffolding protein of postsynaptic density involved in synapse formation, synaptic plasticity, and synaptic targeting of ampa receptors (ampars), which mediate the vast majority of excitatory transmission in the cns. |
2016-04-19 |
2023-08-13 |
mouse |
| X Zhang, X Y Ge, J G Wang, Y L Wang, Y Wang, Y Yu, P P Li, C B L. Induction of long-term oscillations in the γ frequency band by nAChR activation in rat hippocampal CA3 area. Neuroscience. vol 301. 2016-04-18. PMID:26049144. |
we found that hippocampal γ oscillations can be enhanced by a low concentration of nicotine (1μm), such an enhancement lasts for hours after washing out of nicotine, suggesting a form of synaptic plasticity, named as long-term oscillation at γ frequency band (ltoγ). |
2016-04-18 |
2023-08-13 |
rat |
| C Papatheodoropoulo. Striking differences in synaptic facilitation along the dorsoventral axis of the hippocampus. Neuroscience. vol 301. 2016-04-18. PMID:26116517. |
synaptic plasticity is a crucial factor for the function of the hippocampal circuit. |
2016-04-18 |
2023-08-13 |
rat |
| C Papatheodoropoulo. Striking differences in synaptic facilitation along the dorsoventral axis of the hippocampus. Neuroscience. vol 301. 2016-04-18. PMID:26116517. |
i conclude that interactions between the synaptic actions of gababr, gabaar, and nmdar contribute to diversifying short-term synaptic plasticity along the dorsoventral axis of the hippocampus. |
2016-04-18 |
2023-08-13 |
rat |
| Filippo Caraci, Walter Gulisano, Chiara A Guida, Agata A R Impellizzeri, Filippo Drago, Daniela Puzzo, Agostino Palmer. A key role for TGF-β1 in hippocampal synaptic plasticity and memory. Scientific reports. vol 5. 2016-04-12. PMID:26059637. |
a key role for tgf-β1 in hippocampal synaptic plasticity and memory. |
2016-04-12 |
2023-08-13 |
mouse |
| Filippo Caraci, Walter Gulisano, Chiara A Guida, Agata A R Impellizzeri, Filippo Drago, Daniela Puzzo, Agostino Palmer. A key role for TGF-β1 in hippocampal synaptic plasticity and memory. Scientific reports. vol 5. 2016-04-12. PMID:26059637. |
however, its involvement in physiological mechanisms underlying synaptic plasticity and memory at hippocampal level has not been thoroughly investigated. |
2016-04-12 |
2023-08-13 |
mouse |
| Lei An, Tao Zhan. Prenatal melamine exposure induces impairments of spatial cognition and hippocampal synaptic plasticity in male adolescent rats. Reproductive toxicology (Elmsford, N.Y.). vol 49. 2016-04-08. PMID:25111974. |
prenatal melamine exposure induces impairments of spatial cognition and hippocampal synaptic plasticity in male adolescent rats. |
2016-04-08 |
2023-08-13 |
rat |
| Lei An, Tao Zhan. Prenatal melamine exposure induces impairments of spatial cognition and hippocampal synaptic plasticity in male adolescent rats. Reproductive toxicology (Elmsford, N.Y.). vol 49. 2016-04-08. PMID:25111974. |
our previous studies showed that chronic melamine exposure could affect hippocampal synaptic plasticity and impair learning and memory on adult rats. |
2016-04-08 |
2023-08-13 |
rat |
| Kyungmin Lee, Yuki Kobayashi, Hyunhyo Seo, Ji-Hye Kwak, Akira Masuda, Chae-Seok Lim, Hye-Ryeon Lee, SukJae Joshua Kang, Pojeong Park, Su-Eon Sim, Naomi Kogo, Hiroaki Kawasaki, Bong-Kiun Kaang, Shigeyoshi Itohar. Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility. Molecular brain. vol 8. 2016-04-07. PMID:26104314. |
although camp-gef ii is expressed abundantly in several brain areas including the cortex, striatum, and hippocampus, its specific function and possible role in hippocampal synaptic plasticity and cognitive processes remain elusive. |
2016-04-07 |
2023-08-13 |
mouse |
| Hanxiao Liu, Yue Li, Yan Wang, Xinxing Wang, Xu An, Siying Wang, Lin Chen, Guosong Liu, Yupeng Yan. The distinct role of NR2B subunit in the enhancement of visual plasticity in adulthood. Molecular brain. vol 8. 2016-04-07. PMID:26282667. |
the cognitive functions and synaptic plasticity in the hippocampus and prefrontal cortex are elevated following chronic magnesium treatment. |
2016-04-07 |
2023-08-13 |
Not clear |
| Seyed Assad Karimi, Alireza Komaki, Iraj Salehi, Abdolrahman Sarihi, Siamak Shahid. Role of group II metabotropic glutamate receptors (mGluR2/3) blockade on long-term potentiation in the dentate gyrus region of hippocampus in rats fed with high-fat diet. Neurochemical research. vol 40. issue 4. 2016-04-05. PMID:25657067. |
in the hippocampus, metabotropic glutamate receptors (mglurs) are involved in various forms of synaptic plasticity. |
2016-04-05 |
2023-08-13 |
rat |
| Seyed Assad Karimi, Alireza Komaki, Iraj Salehi, Abdolrahman Sarihi, Siamak Shahid. Role of group II metabotropic glutamate receptors (mGluR2/3) blockade on long-term potentiation in the dentate gyrus region of hippocampus in rats fed with high-fat diet. Neurochemical research. vol 40. issue 4. 2016-04-05. PMID:25657067. |
therefore, our results show that ly341495 rescues hippocampal synaptic plasticity that can be impaired by a hfd. |
2016-04-05 |
2023-08-13 |
rat |
| Xuan Qin, Ye Liu, Minghui Zhu, Zhuo Yan. The possible relationship between expressions of TRPC3/5 channels and cognitive changes in rat model of chronic unpredictable stress. Behavioural brain research. vol 290. 2016-04-04. PMID:25958233. |
results suggest that there is an association between expressions of trpc3/5 and cognitive changes in cus rat model, and the mechanism maybe that the different expressions of trpc3/5 can cause morphological changes of the neurons in hippocampus, which has a profound impact on the spatial cognitive ability and synaptic plasticity. |
2016-04-04 |
2023-08-13 |
rat |
| F Harrisberger, R Smieskova, A Schmidt, C Lenz, A Walter, K Wittfeld, H J Grabe, U E Lang, P Fusar-Poli, S Borgward. BDNF Val66Met polymorphism and hippocampal volume in neuropsychiatric disorders: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. vol 55. 2016-03-31. PMID:25956254. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin involved in neurogenesis and synaptic plasticity in the central nervous system, especially in the hippocampus, and has been implicated in the pathophysiology of several neuropsychiatric disorders. |
2016-03-31 |
2023-08-13 |
Not clear |
| Timal S Kannangara, Brennan D Eadie, Crystal A Bostrom, Kristin Morch, Patricia S Brocardo, Brian R Christi. GluN2A-/- Mice Lack Bidirectional Synaptic Plasticity in the Dentate Gyrus and Perform Poorly on Spatial Pattern Separation Tasks. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 8. 2016-03-30. PMID:24554729. |
in the hippocampus, the glun2a and glun2b subunits are particularly abundant; however, their exact roles in synaptic plasticity and behavior remain controversial. |
2016-03-30 |
2023-08-12 |
mouse |
| Zhigang Liu, Ishan Y Patil, Tianyi Jiang, Harsh Sancheti, John P Walsh, Bangyan L Stiles, Fei Yin, Enrique Cadena. High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity. PloS one. vol 10. issue 5. 2016-03-29. PMID:26023930. |
in brain, hfd feeding elicited (a) an inactivation of the irs-1 and, consequentially, (b) a decreased expression and plasma membrane localization of the insulin-sensitive neuronal glucose transporters glut3/glut4; (c) a suppression of the erk/creb pathway, and (d) a substantial decrease in long-term potentiation in the ca1 region of hippocampus (indicative of impaired synaptic plasticity). |
2016-03-29 |
2023-08-13 |
mouse |
| Jane S Sutcliffe, Vahri Beaumont, James M Watson, Chang Sing Chew, Maria Beconi, Daniel M Hutcheson, Celia Dominguez, Ignacio Munoz-Sanjua. Efficacy of selective PDE4D negative allosteric modulators in the object retrieval task in female cynomolgus monkeys (Macaca fascicularis). PloS one. vol 9. issue 7. 2016-03-28. PMID:25050979. |
cyclic adenosine monophosphate (camp) signalling plays an important role in synaptic plasticity and information processing in the hippocampal and basal ganglia systems. |
2016-03-28 |
2023-08-13 |
monkey |