| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Moshe Gross, Anton Sheinin, Elimelech Nesher, Tatiana Tikhonov, Danny Baranes, Albert Pinhasov, Izhak Michaelevsk. Early onset of cognitive impairment is associated with altered synaptic plasticity and enhanced hippocampal GluA1 expression in a mouse model of depression. Neurobiology of aging. vol 36. issue 5. 2016-02-29. PMID:25796132. |
changes in synaptic plasticity were accompanied by markedly reduced hippocampal messenger rna expression of insulin-like growth factor and brain-derived neurotrophic factor. |
2016-02-29 |
2023-08-13 |
mouse |
| Sachie Sasaki-Hamada, Yuki Hojo, Hajime Koyama, Hayuma Otsuka, Jun-Ichiro Ok. Changes in hippocampal synaptic functions and protein expression in monosodium glutamate-treated obese mice during development of glucose intolerance. The European journal of neuroscience. vol 41. issue 11. 2016-02-29. PMID:25851080. |
although hippocampal synaptic plasticity is impaired in msg-treated mice, changes in synaptic transmission remain unknown. |
2016-02-29 |
2023-08-13 |
mouse |
| Albert Giralt, Ana Saavedra, Jordi Alberch, Esther Pérez-Navarr. Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms. Journal of Huntington's disease. vol 1. issue 2. 2016-02-23. PMID:25063329. |
alterations in hippocampal synaptic plasticity and function found in hd mouse models highlight that changes in the functioning of the hippocampal formation contribute to cognitive dysfunction in humans. |
2016-02-23 |
2023-08-13 |
mouse |
| Huili Han, Zhifang Dong, Yunfang Jia, Rongrong Mao, Qixin Zhou, Yuexiong Yang, Liping Wang, Lin Xu, Jun Ca. Opioid addiction and withdrawal differentially drive long-term depression of inhibitory synaptic transmission in the hippocampus. Scientific reports. vol 5. 2016-02-23. PMID:25942289. |
it has been well documented that adaptations of synaptic plasticity of excitatory transmission in the hippocampus may contribute to opioid addiction. |
2016-02-23 |
2023-08-13 |
Not clear |
| Huili Han, Zhifang Dong, Yunfang Jia, Rongrong Mao, Qixin Zhou, Yuexiong Yang, Liping Wang, Lin Xu, Jun Ca. Opioid addiction and withdrawal differentially drive long-term depression of inhibitory synaptic transmission in the hippocampus. Scientific reports. vol 5. 2016-02-23. PMID:25942289. |
however, it remains unknown whether and how adaptive changes of synaptic plasticity of inhibitory transmission in the hippocampus occurs during opioid abuse. |
2016-02-23 |
2023-08-13 |
Not clear |
| Qingqing Li, Fangfang Qi, Junhua Yang, Luwen Zhang, Huaiyu Gu, Juntao Zou, Qunfang Yuan, Zhibin Ya. Neonatal vaccination with bacillus Calmette-Guérin and hepatitis B vaccines modulates hippocampal synaptic plasticity in rats. Journal of neuroimmunology. vol 288. 2016-02-23. PMID:26531688. |
neonatal vaccination with bacillus calmette-guérin and hepatitis b vaccines modulates hippocampal synaptic plasticity in rats. |
2016-02-23 |
2023-08-13 |
rat |
| Qingqing Li, Fangfang Qi, Junhua Yang, Luwen Zhang, Huaiyu Gu, Juntao Zou, Qunfang Yuan, Zhibin Ya. Neonatal vaccination with bacillus Calmette-Guérin and hepatitis B vaccines modulates hippocampal synaptic plasticity in rats. Journal of neuroimmunology. vol 288. 2016-02-23. PMID:26531688. |
our study demonstrates the influence of neonatal vaccination on hippocampal synaptic plasticity in rats under normal physiological conditions. |
2016-02-23 |
2023-08-13 |
rat |
| Nicole M Wilson, David J Titus, Anthony A Oliva, Concepcion Furones, Coleen M Atkin. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Frontiers in systems neuroscience. vol 10. 2016-02-23. PMID:26903822. |
traumatic brain injury (tbi) results in significant impairments in hippocampal synaptic plasticity. |
2016-02-23 |
2023-08-13 |
rat |
| Nicole M Wilson, David J Titus, Anthony A Oliva, Concepcion Furones, Coleen M Atkin. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Frontiers in systems neuroscience. vol 10. 2016-02-23. PMID:26903822. |
a molecule critically involved in hippocampal synaptic plasticity, 3',5'-cyclic adenosine monophosphate, is downregulated in the hippocampus after tbi, but the mechanism that underlies this decrease is unknown. |
2016-02-23 |
2023-08-13 |
rat |
| Nicole M Wilson, David J Titus, Anthony A Oliva, Concepcion Furones, Coleen M Atkin. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Frontiers in systems neuroscience. vol 10. 2016-02-23. PMID:26903822. |
to determine if inhibition of pde4 would improve hippocampal synaptic plasticity deficits after tbi, we treated hippocampal slices with rolipram, a pan-pde4 inhibitor. |
2016-02-23 |
2023-08-13 |
rat |
| Nicole M Wilson, David J Titus, Anthony A Oliva, Concepcion Furones, Coleen M Atkin. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Frontiers in systems neuroscience. vol 10. 2016-02-23. PMID:26903822. |
overall, these results identify several possible pde targets for reducing hippocampal synaptic plasticity deficits and improving cognitive function acutely after tbi. |
2016-02-23 |
2023-08-13 |
rat |
| Julien Bensalem, Laure Servant, Serge Alfos, David Gaudout, Sophie Layé, Véronique Pallet, Pauline Lafenetr. Dietary Polyphenol Supplementation Prevents Alterations of Spatial Navigation in Middle-Aged Mice. Frontiers in behavioral neuroscience. vol 10. 2016-02-23. PMID:26903826. |
spatial learning and memory deficits associated with hippocampal synaptic plasticity impairments are commonly observed during aging. |
2016-02-23 |
2023-08-13 |
mouse |
| Niels Hansen, Denise Manahan-Vaugha. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 7. 2016-02-19. PMID:24464942. |
synaptic plasticity comprises a cellular mechanism through which the hippocampus most likely enables memory formation. |
2016-02-19 |
2023-08-12 |
rat |
| Fumiaki Yokoi, Huan-Xin Chen, Mai Tu Dang, Chad C Cheetham, Susan L Campbell, Steven N Roper, J David Sweatt, Yuqing L. Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice. PloS one. vol 10. issue 3. 2016-02-19. PMID:25799505. |
although dyt1 ki mice show decreased hippocampal torsina levels, it is not clear whether the decreased torsina level itself affects the synaptic plasticity or torsina(Δe) does it. |
2016-02-19 |
2023-08-13 |
mouse |
| Julien Braga Calais, Elida Benquique Ojopi, Edgard Morya, Koichi Sameshima, Sidarta Ribeir. Experience-dependent upregulation of multiple plasticity factors in the hippocampus during early REM sleep. Neurobiology of learning and memory. vol 122. 2016-02-18. PMID:25626078. |
to advance this issue, we used real-time pcr and electrophysiological recordings to assess gene expression related to synaptic plasticity in the hippocampus and primary somatosensory cortex of rats exposed to novel objects, then kept awake (wk) for 60 min and finally killed after a 30 min period rich in wk, slow-wave sleep (sws) or rapid-eye-movement sleep (rem). |
2016-02-18 |
2023-08-13 |
rat |
| Katsuya Ogata, Norihito Shintani, Atsuko Hayata-Takano, Toshihiko Kamo, Shintaro Higashi, Kaoru Seiriki, Hisae Momosaki, David Vaudry, Hubert Vaudry, Ludovic Galas, Atsushi Kasai, Kazuki Nagayasu, Takanobu Nakazawa, Ryota Hashimoto, Yukio Ago, Toshio Matsuda, Akemichi Baba, Hitoshi Hashimot. PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF. PloS one. vol 10. issue 3. 2016-02-17. PMID:25807538. |
pituitary adenylate cyclase-activating polypeptide (pacap) exerts neurotrophic activities including modulation of synaptic plasticity and memory, hippocampal neurogenesis, and neuroprotection, most of which are shared with brain-derived neurotrophic factor (bdnf). |
2016-02-17 |
2023-08-13 |
Not clear |
| Bianca De Filippis, Daniela Valenti, Valentina Chiodi, Antonella Ferrante, Lidia de Bari, Carla Fiorentini, Maria Rosaria Domenici, Laura Ricceri, Rosa Anna Vacca, Alessia Fabbri, Giovanni Laviol. Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25890884. |
restored mitochondrial functionality was accompanied by the rescue of deficits in cognitive function (spatial reference memory in the barnes maze), synaptic plasticity (long-term potentiation) and tyr1472 phosphorylation of glun2b, which was abnormally enhanced in the hippocampus of rtt mice. |
2016-02-16 |
2023-08-13 |
mouse |
| Fatemeh Saffarzadeh, Mohammad J Eslamizade, Tahereh Ghadiri, Sayed Mostafa Modarres Mousavi, Mahmoudreza Hadjighassem, Ali Gorj. Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain. Synapse (New York, N.Y.). vol 69. issue 7. 2016-02-12. PMID:25967571. |
effects of trpv1 on the hippocampal synaptic plasticity in the epileptic rat brain. |
2016-02-12 |
2023-08-13 |
rat |
| Fatemeh Saffarzadeh, Mohammad J Eslamizade, Tahereh Ghadiri, Sayed Mostafa Modarres Mousavi, Mahmoudreza Hadjighassem, Ali Gorj. Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain. Synapse (New York, N.Y.). vol 69. issue 7. 2016-02-12. PMID:25967571. |
these findings indicate that a higher expression of trpv1 in epileptic conditions is accompanied by a functional impact on the synaptic plasticity in the hippocampus. |
2016-02-12 |
2023-08-13 |
rat |
| Joerg Schreiber, Marlene J Végh, Julia Dawitz, Tim Kroon, Maarten Loos, Dorthe Labonté, Ka Wan Li, Pim Van Nierop, Michiel T Van Diepen, Chris I De Zeeuw, Matthias Kneussel, Rhiannon M Meredith, August B Smit, Ronald E Van Kestere. Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. The Journal of cell biology. vol 211. issue 3. 2016-02-12. PMID:26527743. |
we propose a model in which trim3 regulates synaptic γ-actin turnover and actin filament stability and thus forms a transient inhibitory constraint on the expression of hippocampal synaptic plasticity. |
2016-02-12 |
2023-08-13 |
mouse |