| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jerrel L Yake. Nicotinic ACh receptors in the hippocampal circuit; functional expression and role in synaptic plasticity. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:24860170. |
the primary cholinergic input to the hippocampus arises from the medial septum and diagonal band of broca (ms-dbb), and we investigated how their activation regulated hippocampal synaptic plasticity. |
2015-06-10 |
2023-08-13 |
Not clear |
| Jerrel L Yake. Nicotinic ACh receptors in the hippocampal circuit; functional expression and role in synaptic plasticity. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:24860170. |
we found that activation of these endogenous cholinergic inputs can directly induce different forms of hippocampal synaptic plasticity with a timing precision in the millisecond range. |
2015-06-10 |
2023-08-13 |
Not clear |
| Jerrel L Yake. Nicotinic ACh receptors in the hippocampal circuit; functional expression and role in synaptic plasticity. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:24860170. |
we propose that α7 nachrs coordinate pre- and postsynaptic activities to induce glutamatergic synaptic plasticity, and thus provide a novel mechanism underlying physiological neuronal communication that could lead to timing-dependent synaptic plasticity in the hippocampus. |
2015-06-10 |
2023-08-13 |
Not clear |
| Nahla Zaghloul, Hardik Patel, Champa Codipilly, Philippe Marambaud, Stephen Dewey, Stephen Frattini, Patricio T Huerta, Mansoor Nasim, Edmund J Miller, Mohamed Ahme. Overexpression of extracellular superoxide dismutase protects against brain injury induced by chronic hypoxia. PloS one. vol 9. issue 9. 2015-06-10. PMID:25268361. |
to investigate the functional state of the hippocampus, electrophysiological techniques in ex vivo hippocampal slices were performed and showed that h-ki had normal synaptic plasticity, whereas h-wt were severely affected. |
2015-06-10 |
2023-08-13 |
mouse |
| Elena Dale, Hong Zhang, Steven C Leiser, Yixin Xiao, Dunguo Lu, Charles R Yang, Niels Plath, Connie Sanche. Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus. Journal of psychopharmacology (Oxford, England). vol 28. issue 10. 2015-06-09. PMID:25122043. |
vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus. |
2015-06-09 |
2023-08-13 |
rat |
| Elena Dale, Hong Zhang, Steven C Leiser, Yixin Xiao, Dunguo Lu, Charles R Yang, Niels Plath, Connie Sanche. Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus. Journal of psychopharmacology (Oxford, England). vol 28. issue 10. 2015-06-09. PMID:25122043. |
taken together, our results indicate that vortioxetine can increase pyramidal cell output, which leads to enhanced synaptic plasticity in the hippocampus. |
2015-06-09 |
2023-08-13 |
rat |
| Miranda C Staples, Morgan W Porch, Daniel D Savag. Impact of combined prenatal ethanol and prenatal stress exposures on markers of activity-dependent synaptic plasticity in rat dentate gyrus. Alcohol (Fayetteville, N.Y.). vol 48. issue 6. 2015-06-09. PMID:25129673. |
prenatal ethanol exposure and prenatal stress can each cause long-lasting deficits in hippocampal synaptic plasticity and disrupt learning and memory processes. |
2015-06-09 |
2023-08-13 |
rat |
| Nicole E Brown, Devrishi Goswami, Mary Rose Branch, Suneela Ramineni, Eric A Ortlund, Patrick R Griffin, John R Heple. Integration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14). The Journal of biological chemistry. vol 290. issue 14. 2015-06-09. PMID:25666614. |
based on these findings, we propose a working model for how rgs14 integrates multiple g protein signals in host ca2 hippocampal neurons to modulate synaptic plasticity. |
2015-06-09 |
2023-08-13 |
Not clear |
| K Kinugawa, V H Nguyen-Michel, J Marian. [Obstructive sleep apnea syndrome: a cause of cognitive disorders in the elderly?]. La Revue de medecine interne. vol 35. issue 10. 2015-06-08. PMID:24630586. |
the obstructive sleep apnea syndrome with cognitive impairment shares some features with alzheimer's disease, involving genetic predisposition apoe4, hippocampus and synaptic plasticity abnormalities. |
2015-06-08 |
2023-08-12 |
human |
| Marlene J Végh, Céline M Heldring, Willem Kamphuis, Sara Hijazi, Arie J Timmerman, Ka Wan Li, Pim van Nierop, Huibert D Mansvelder, Elly M Hol, August B Smit, Ronald E van Kestere. Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease. Acta neuropathologica communications. vol 2. 2015-05-29. PMID:24974208. |
here we used appswe/ps1de9 (app/ps1) transgenic mice to study the early pre-pathological effects of increased amyloid-β levels on hippocampal synaptic plasticity and memory. |
2015-05-29 |
2023-08-13 |
mouse |
| Chen Bian, Haitao Zhu, Yangang Zhao, Wenqin Cai, Jiqiang Zhan. Intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. Journal of molecular neuroscience : MN. vol 54. issue 2. 2015-05-28. PMID:24729128. |
intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. |
2015-05-28 |
2023-08-13 |
Not clear |
| Chen Bian, Haitao Zhu, Yangang Zhao, Wenqin Cai, Jiqiang Zhan. Intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. Journal of molecular neuroscience : MN. vol 54. issue 2. 2015-05-28. PMID:24729128. |
accumulated studies have shown that 17β-estradiol (e2) can be de novo synthesized in the hippocampus, and its role in the regulation of hippocampal synaptic plasticity, which is the basis of learning and memory, has long been exploring. |
2015-05-28 |
2023-08-13 |
Not clear |
| Chen Bian, Haitao Zhu, Yangang Zhao, Wenqin Cai, Jiqiang Zhan. Intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. Journal of molecular neuroscience : MN. vol 54. issue 2. 2015-05-28. PMID:24729128. |
the influences of gonadal and hippocampal e2 on synaptic plasticity may exist some differences, since some reports showed that gonadal (or circulating) estrogens have no obvious effects in the modulation of hippocampal synaptic proteins as evidenced in some ovariectomized animals and postmenopausal women who suffered from alzheimer's disease (ad). |
2015-05-28 |
2023-08-13 |
Not clear |
| Chen Bian, Haitao Zhu, Yangang Zhao, Wenqin Cai, Jiqiang Zhan. Intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. Journal of molecular neuroscience : MN. vol 54. issue 2. 2015-05-28. PMID:24729128. |
these evidences leads to a hypothesis that hippocampal e2 may play a more important role in modulation of synaptic plasticity than gonadal e2. |
2015-05-28 |
2023-08-13 |
Not clear |
| Chen Bian, Haitao Zhu, Yangang Zhao, Wenqin Cai, Jiqiang Zhan. Intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. Journal of molecular neuroscience : MN. vol 54. issue 2. 2015-05-28. PMID:24729128. |
the signaling pathways, whereby hippocampal e2 modulates synaptic plasticity, insist of classical chronic genomic pathway and rapid nongenomic pathway, which mediated by nonnuclear estrogen receptor (gper) and/or nuclear or nonnuclear estrogen receptors, which require coactivators for their transcription activity. |
2015-05-28 |
2023-08-13 |
Not clear |
| Chen Bian, Haitao Zhu, Yangang Zhao, Wenqin Cai, Jiqiang Zhan. Intriguing roles of hippocampus-synthesized 17β-estradiol in the modulation of hippocampal synaptic plasticity. Journal of molecular neuroscience : MN. vol 54. issue 2. 2015-05-28. PMID:24729128. |
several clues have shown that src-1 is expressed in hippocampus and is highly correlated with some key synaptic proteins developmentally or after orchidectomy but not ovariectomy, indicating src-1 may be regulated by hippocampus-synthesized e2 and profoundly involved in the mediation of hippocampal e2 regulation of hippocampal synaptic plasticity. |
2015-05-28 |
2023-08-13 |
Not clear |
| Lei An, Tao Zhan. Vitamins C and E reverse melamine-induced deficits in spatial cognition and hippocampal synaptic plasticity in rats. Neurotoxicology. vol 44. 2015-05-27. PMID:24960222. |
vitamins c and e reverse melamine-induced deficits in spatial cognition and hippocampal synaptic plasticity in rats. |
2015-05-27 |
2023-08-13 |
rat |
| Lei An, Tao Zhan. Vitamins C and E reverse melamine-induced deficits in spatial cognition and hippocampal synaptic plasticity in rats. Neurotoxicology. vol 44. 2015-05-27. PMID:24960222. |
the vitamins c plus e regimen mitigated melamine-induced impairment of hippocampal synaptic plasticity. |
2015-05-27 |
2023-08-13 |
rat |
| Cailin M Rothwell, Jason Simmons, Grace Peters, Gaynor E Spence. Novel interactive effects of darkness and retinoid signaling in the ability to form long-term memory following aversive operant conditioning. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:25062644. |
the vitamin a metabolite, retinoic acid, is important for memory formation and hippocampal synaptic plasticity in vertebrate species. |
2015-05-22 |
2023-08-13 |
Not clear |
| Mohamed Ghilan, Crystal A Bostrom, Brett N Hryciw, Jessica M Simpson, Brian R Christie, Joana Gil-Mohape. YAC128 Huntington's disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease. Brain research. vol 1581. 2015-05-21. PMID:24949563. |
yac128 huntington's disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease. |
2015-05-21 |
2023-08-13 |
mouse |