| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohamed Ghilan, Crystal A Bostrom, Brett N Hryciw, Jessica M Simpson, Brian R Christie, Joana Gil-Mohape. YAC128 Huntington's disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease. Brain research. vol 1581. 2015-05-21. PMID:24949563. |
thus, the purpose of this study was to evaluate whether short- and long-term synaptic plasticity in the hippocampus, two related biological models of learning and memory processes, were altered in yac128 mice in early stages of disease progression. |
2015-05-21 |
2023-08-13 |
mouse |
| Y He, D Kulasiri, S Samarasingh. Systems biology of synaptic plasticity: a review on N-methyl-D-aspartate receptor mediated biochemical pathways and related mathematical models. Bio Systems. vol 122. 2015-05-20. PMID:24929130. |
in this paper, we first review the well understood modulators and mechanisms underlying n-methyl-d-aspartate receptor dependent synaptic plasticity, a major form of synaptic plasticity in hippocampus, and then comment on the key mathematical modelling approaches available in the literature to understand synaptic plasticity as the integration of the established functionalities of synaptic components. |
2015-05-20 |
2023-08-13 |
Not clear |
| Kayla M Quinnies, Paul J Bonthuis, Erin P Harris, Savera Rj Shetty, Emilie F Rissma. Neural growth hormone: regional regulation by estradiol and/or sex chromosome complement in male and female mice. Biology of sex differences. vol 6. 2015-05-19. PMID:25987976. |
gh and its receptor are also produced in the brain where they may impact cognitive function and synaptic plasticity, and estradiol produces gh sex differences in rat hippocampus. |
2015-05-19 |
2023-08-13 |
mouse |
| Xing-Hua Yue, Xiao-Jie Liu, Mei-Na Wu, Jin-Yuan Chen, Jin-Shun Q. [Amyloid β protein suppresses hippocampal theta rhythm and induces behavioral disinhibition and spatial memory deficit in rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 2. 2015-05-16. PMID:24777399. |
these experimental results indicate that intrahippocampal injection of aβ(1-42) can induce behavioral disinhibition and theta rhythm suppression, as well as spatial memory impairment in rats, which suggests that the cognition deficits and behavior impairments in ad are probably associated with the aβ-induced disruption of hippocampal theta rhythm and consequent down-regulation of synaptic plasticity. |
2015-05-16 |
2023-08-13 |
rat |
| Dong-Hoon Yoon, Sehyoun Yoon, Donghoon Kim, Hyun Kim, Ja-Hyun Bai. Regulation of dopamine D2 receptor-mediated extracellular signal-regulated kinase signaling and spine formation by GABAA receptors in hippocampal neurons. Neuroscience letters. vol 586. 2015-05-14. PMID:25483619. |
dopamine (da) signaling via da receptors is known to control hippocampal activity that contributes to learning, memory, and synaptic plasticity. |
2015-05-14 |
2023-08-13 |
Not clear |
| Anna M Barron, Yasushi Hojo, Hideo Mukai, Shimpei Higo, Yuuki Ooishi, Yusuke Hatanaka, Mari Ogiue-Ikeda, Gen Murakami, Tetsuya Kimoto, Suguru Kawat. Regulation of synaptic plasticity by hippocampus synthesized estradiol. Hormone molecular biology and clinical investigation. vol 7. issue 2. 2015-05-13. PMID:25961274. |
regulation of synaptic plasticity by hippocampus synthesized estradiol. |
2015-05-13 |
2023-08-13 |
rat |
| Anna M Barron, Yasushi Hojo, Hideo Mukai, Shimpei Higo, Yuuki Ooishi, Yusuke Hatanaka, Mari Ogiue-Ikeda, Gen Murakami, Tetsuya Kimoto, Suguru Kawat. Regulation of synaptic plasticity by hippocampus synthesized estradiol. Hormone molecular biology and clinical investigation. vol 7. issue 2. 2015-05-13. PMID:25961274. |
locally synthesized estradiol rapidly and potently modulates synaptic plasticity within the hippocampus. |
2015-05-13 |
2023-08-13 |
rat |
| Liang Chen, Yanyan Miao, Lin Chen, Jing Xu, Xinxing Wang, Han Zhao, Yi Shen, Yi Hu, Yunpeng Bian, Yuanyuan Shen, Jutao Chen, Yingying Zha, Long-Ping Wen, Ming Wan. The role of low levels of fullerene C60 nanocrystals on enhanced learning and memory of rats through persistent CaMKII activation. Biomaterials. vol 35. issue 34. 2015-05-12. PMID:25129570. |
fullerene nanoparticles have been reported to specifically bind to and elicit persistent activation of hippocampal ca(2+)/calmodulin-dependent protein kinase ii (camkii), a multimeric intracellular serine/threonine kinase central to ca(2+) signal transduction and critical for synaptic plasticity, but the functional consequence of that modulation is unknown. |
2015-05-12 |
2023-08-13 |
rat |
| Jonathan E Cohen, Philip R Lee, R Douglas Field. Systematic identification of 3'-UTR regulatory elements in activity-dependent mRNA stability in hippocampal neurons. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1652. 2015-05-12. PMID:25135970. |
we have identified a mechanism that contributes to activity-dependent regulation of mrna stability during synaptic plasticity in rat hippocampal neurons. |
2015-05-12 |
2023-08-13 |
rat |
| M Labarrière, F Thomas, P Dutar, L Pollegioni, H Wolosker, J-M Billar. Circuit-specific changes in D-serine-dependent activation of the N-methyl-D-aspartate receptor in the aging hippocampus. Age (Dordrecht, Netherlands). vol 36. issue 5. 2015-05-12. PMID:25138794. |
thus, our study indicates that although nmda-r-dependent mechanisms driving synaptic plasticity are quite similar between hippocampal circuits, they show regional differences in their susceptibility to aging, which could hamper the development of effective therapeutic strategies aimed at reducing cognitive aging. |
2015-05-12 |
2023-08-13 |
rat |
| Lu Xiong, Cheng Feng Sun, Jing Zhang, Ya Bing Gao, Li Feng Wang, Hong Yan Zuo, Shui Ming Wang, Hong Mei Zhou, Xin Ping Xu, Ji Dong, Bin Wei Yao, Li Zhao, Rui Yun Pen. Microwave exposure impairs synaptic plasticity in the rat hippocampus and PC12 cells through over-activation of the NMDA receptor signaling pathway. Biomedical and environmental sciences : BES. vol 28. issue 1. 2015-05-08. PMID:25566859. |
microwave exposure impairs synaptic plasticity in the rat hippocampus and pc12 cells through over-activation of the nmda receptor signaling pathway. |
2015-05-08 |
2023-08-13 |
rat |
| Bianca De Filippis, Valentina Chiodi, Walter Adriani, Enza Lacivita, Cinzia Mallozzi, Marcello Leopoldo, Maria Rosaria Domenici, Andrea Fuso, Giovanni Laviol. Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-04-30. PMID:25926782. |
the present study extends previous findings by demonstrating that the lp-211 treatment (0.25 mg/kg, once per day for 7 days) rescues rtt-related phenotypic alterations, motor coordination (dowel test), spatial reference memory (barnes maze test) and synaptic plasticity (hippocampal long-term-potentiation) in mecp2-308 heterozygous female mice, the genetic and hormonal milieu that resembles that of rtt patients. |
2015-04-30 |
2023-08-13 |
mouse |
| Olivia A Shipton, Mohamady El-Gaby, John Apergis-Schoute, Karl Deisseroth, David M Bannerman, Ole Paulsen, Michael M Koh. Left-right dissociation of hippocampal memory processes in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 42. 2015-04-24. PMID:25246561. |
here we examined whether lateralized hippocampal memory processing is present in mice, where hemispheric asymmetry at the ca3-ca1 pyramidal neuron synapse has recently been demonstrated, with different spine morphology, glutamate receptor content, and synaptic plasticity, depending on whether afferents originate in the left or right ca3. |
2015-04-24 |
2023-08-13 |
mouse |
| Saeideh Jafarinejad-Farsangi, Ali Farazmand, Ameneh Rezayof, Niloufar Darband. Proteome Analysis of Rat Hippocampus Following Morphine-induced Amnesia and State-dependent Learning. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 2. 2015-04-22. PMID:25901168. |
morphine's effects on learning and memory processes are well known to depend on synaptic plasticity in the hippocampus. |
2015-04-22 |
2023-08-13 |
rat |
| Sharmilee Gnanapavan, Gavin Giovannon. Neural cell adhesion molecules in brain plasticity and disease. Multiple sclerosis and related disorders. vol 2. issue 1. 2015-04-17. PMID:25877450. |
ncam is important in neurite outgrowth, long-term potentiation in the hippocampus and synaptic plasticity. |
2015-04-17 |
2023-08-13 |
Not clear |
| Jun-Hyeok Choi, Pojeong Park, Gi-Chul Baek, Su-Eon Sim, SukJae Joshua Kang, Yeseul Lee, Seo-Hee Ahn, Chae-Seok Lim, Yong-Seok Lee, Graham L Collingridge, Bong-Kiun Kaan. Effects of PI3Kγ overexpression in the hippocampus on synaptic plasticity and spatial learning. Molecular brain. vol 7. 2015-04-15. PMID:25373491. |
effects of pi3kγ overexpression in the hippocampus on synaptic plasticity and spatial learning. |
2015-04-15 |
2023-08-13 |
mouse |
| Victor Briz, Guoqi Zhu, Yubin Wang, Yan Liu, Mariam Avetisyan, Xiaoning Bi, Michel Baudr. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 5. 2015-04-14. PMID:25653381. |
activity-dependent rapid local rhoa synthesis is required for hippocampal synaptic plasticity. |
2015-04-14 |
2023-08-13 |
rat |
| Elizabeth M Waters, Louisa I Thompson, Parth Patel, Andreina D Gonzales, Hector Zhiyu Ye, Edward J Filardo, Deborah J Clegg, Jolanta Gorecka, Keith T Akama, Bruce S McEwen, Teresa A Milne. G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 6. 2015-04-13. PMID:25673833. |
g-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. |
2015-04-13 |
2023-08-13 |
mouse |
| Elizabeth M Waters, Louisa I Thompson, Parth Patel, Andreina D Gonzales, Hector Zhiyu Ye, Edward J Filardo, Deborah J Clegg, Jolanta Gorecka, Keith T Akama, Bruce S McEwen, Teresa A Milne. G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 6. 2015-04-13. PMID:25673833. |
here, we examined whether the membrane estrogen receptor, g-protein-coupled estrogen receptor 1 (gper1), is anatomically positioned in the dorsal hippocampus of mice to regulate synaptic plasticity. |
2015-04-13 |
2023-08-13 |
mouse |
| Sanjeev K Bhardwaj, Richard T Ryan, Tak Pan Wong, Lalit K Srivastav. Loss of dysbindin-1, a risk gene for schizophrenia, leads to impaired group 1 metabotropic glutamate receptor function in mice. Frontiers in behavioral neuroscience. vol 9. 2015-04-10. PMID:25859193. |
aberrant mgluri-erk1/2 signaling affected hippocampal synaptic plasticity in the sdy mutants as dhpg-induced long-term depression (ltd) at ca1 excitatory synapses was significantly reduced. |
2015-04-10 |
2023-08-13 |
mouse |