| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuya Fukumoto, Hiroyuki Mizoguchi, Hideyuki Takeuchi, Hiroshi Horiuchi, Jun Kawanokuchi, Shijie Jin, Tetsuya Mizuno, Akio Suzumur. Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment. Behavioural brain research. vol 268. 2014-12-16. PMID:24713151. |
amyloid β, a neurotoxic protein, causes disruption of hippocampal synaptic plasticity, and induces cognitive impairment in alzheimer's disease. |
2014-12-16 |
2023-08-13 |
mouse |
| Chanel J Taylor, RongQiao He, Perry F Bartlet. The role of the N-methyl-D-aspartate receptor in the proliferation of adult hippocampal neural stem and precursor cells. Science China. Life sciences. vol 57. issue 4. 2014-12-16. PMID:24777380. |
hippocampal-dependent learning tasks, enriched environments, running, and activity-dependent synaptic plasticity, all potently up-regulate hippocampal nspc proliferation. |
2014-12-16 |
2023-08-13 |
Not clear |
| R Angela Sarabdjitsingh, Ming Zhou, Joyce L W Yau, Scott P Webster, Brian R Walker, Jonathan R Seckl, Marian Joëls, Harm J Kruger. Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning. Neuropharmacology. vol 81. 2014-12-15. PMID:24495397. |
inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning. |
2014-12-15 |
2023-08-12 |
Not clear |
| R Angela Sarabdjitsingh, Ming Zhou, Joyce L W Yau, Scott P Webster, Brian R Walker, Jonathan R Seckl, Marian Joëls, Harm J Kruger. Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning. Neuropharmacology. vol 81. 2014-12-15. PMID:24495397. |
these observations suggest that local metabolism of glucocorticoids is relevant for the outcome of stress effects on hippocampal synaptic plasticity and contextual fear conditioning. |
2014-12-15 |
2023-08-12 |
Not clear |
| Shirin Babri, Gisou Mohaddes, Iraj Feizi, Alireza Mohammadnia, Ali Niapour, Alireza Alihemmati, Mohammad Aman. Effect of troxerutin on synaptic plasticity of hippocampal dentate gyrus neurons in a β-amyloid model of Alzheimer׳s disease: an electrophysiological study. European journal of pharmacology. vol 732. 2014-12-09. PMID:24681055. |
effect of troxerutin on synaptic plasticity of hippocampal dentate gyrus neurons in a β-amyloid model of alzheimer׳s disease: an electrophysiological study. |
2014-12-09 |
2023-08-12 |
rat |
| Junsi Zhang, Yanna Li, Jing Xu, Zhou Yan. The role of N-methyl-D-aspartate receptor in Alzheimer's disease. Journal of the neurological sciences. vol 339. issue 1-2. 2014-12-08. PMID:24548486. |
the synaptic plasticity was measured by recording long-term potentiation (ltp) and depression (ltd) in the perforant path (pp) to dentate gyrus (dg) of hippocampus. |
2014-12-08 |
2023-08-12 |
rat |
| Pei Jiang, Rui-Li Dang, Huan-De Li, Li-Hong Zhang, Wen-Ye Zhu, Ying Xue, Mi-Mi Tan. The impacts of swimming exercise on hippocampal expression of neurotrophic factors in rats exposed to chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-12-05. PMID:25477997. |
depression is associated with stress-induced neural atrophy in limbic brain regions, whereas exercise has antidepressant effects as well as increasing hippocampal synaptic plasticity by strengthening neurogenesis, metabolism, and vascular function. |
2014-12-05 |
2023-08-13 |
rat |
| Dragos Inta, Miriam A Vogt, Hasan Elkin, Tillmann Weber, Juan M Lima-Ojeda, Miriam Schneider, Alessia Luoni, Marco A Riva, Karen Gertz, Julian Hellmann-Regen, Golo Kronenberg, Andreas Meyer-Lindenberg, Rolf Sprengel, Peter Gas. Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: relevance for mental disorders. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24339333. |
glua1-containing ampa receptors, which are located predominantly on hippocampal neurons, are the primary molecular determinants of synaptic plasticity. |
2014-12-03 |
2023-08-12 |
mouse |
| Sha Sha, Libin Zhou, Jun Yin, Koga Takamiya, Keiko Furukawa, Koichi Furukawa, Masahiro Sokabe, Ling Che. Deficits in cognitive function and hippocampal plasticity in GM2/GD2 synthase knockout mice. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24765676. |
in this study, we used gm2/gd2 synthase knockout (gm2/gd2−/−) mice to examine the influence of deficiency in ganglioside “a-pathway” and “b-pathway” on cognitive performances and hippocampal synaptic plasticity. |
2014-12-03 |
2023-08-13 |
mouse |
| Mimi A Trinh, Tao Ma, Hanoch Kaphzan, Aditi Bhattacharya, Marcia D Antion, Douglas R Cavener, Charles A Hoeffer, Eric Klan. The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 5. 2014-12-01. PMID:24741110. |
to determine the role of perk in hippocampal synaptic plasticity, we used the cre-lox expression system to selectively disrupt perk expression in the adult mouse forebrain. |
2014-12-01 |
2023-08-13 |
mouse |
| Wei-Hua Lee, Ashok Kumar, Asha Rani, Thomas C Foste. Role of antioxidant enzymes in redox regulation of N-methyl-D-aspartate receptor function and memory in middle-aged rats. Neurobiology of aging. vol 35. issue 6. 2014-11-25. PMID:24388786. |
overexpression of superoxide dismutase 1 (sod1) in the hippocampus results in age-dependent impaired cognition and altered synaptic plasticity suggesting a possible model for examining the role of oxidative stress in senescent neurophysiology. |
2014-11-25 |
2023-08-12 |
rat |
| Hidetoshi Urakubo, Miharu Sato, Shin Ishii, Shinya Kurod. In vitro reconstitution of a CaMKII memory switch by an NMDA receptor-derived peptide. Biophysical journal. vol 106. issue 6. 2014-11-25. PMID:24655517. |
these functions may be crucial for induction and maintenance of long-term synaptic plasticity at hippocampal synapses. |
2014-11-25 |
2023-08-12 |
Not clear |
| Giulia Quattrocolo, Gianmaria Maccaferr. Optogenetic activation of cajal-retzius cells reveals their glutamatergic output and a novel feedforward circuit in the developing mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 39. 2014-11-25. PMID:25253849. |
we propose that this newly defined cajal-retzius cell-dependent microcircuit may regulate synaptic plasticity and dendritic development in stratum lacunosum-moleculare, thus impacting the integrative properties of the developing hippocampus. |
2014-11-25 |
2023-08-13 |
mouse |
| Madhusudhanan M Keralapurath, Jason K Clark, Sherri Hammond, John J Wagne. Cocaine- or stress-induced metaplasticity of LTP in the dorsal and ventral hippocampus. Hippocampus. vol 24. issue 5. 2014-11-24. PMID:24464838. |
despite the well documented role of the hippocampus in various modes of drug reinstatement behavior, the persisting effects of in vivo cocaine exposure on hippocampal synaptic plasticity are not sufficiently understood. |
2014-11-24 |
2023-08-12 |
rat |
| Xue-Mei Liao, Xiao-Dun Yang, Jiao Jia, Ji-Tao Li, Xiao-Meng Xie, Yun-Ai Su, Mathias V Schmidt, Tian-Mei Si, Xiao-Dong Wan. Blockade of corticotropin-releasing hormone receptor 1 attenuates early-life stress-induced synaptic abnormalities in the neonatal hippocampus. Hippocampus. vol 24. issue 5. 2014-11-24. PMID:24493406. |
adult individuals with early stressful experience exhibit impaired hippocampal neuronal morphology, synaptic plasticity and cognitive performance. |
2014-11-24 |
2023-08-12 |
mouse |
| Vélvá M Combs, Heather D Crispell, Kelly L Dre. D-cycloserine 24 and 48 hours after asphyxial cardiac arrest has no effect on hippocampal CA1 neuropathology. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 10. 2014-11-24. PMID:25099755. |
stimulation of nmdar with the partial nmdar agonist d-cycloserine (dcs) improves outcome and restores hippocampal synaptic plasticity in models of closed head injury. |
2014-11-24 |
2023-08-13 |
rat |
| Wenyu Cao, Juan Duan, Xueqin Wang, Xiaolin Zhong, Zhaolan Hu, Fulian Huang, Hongtao Wang, Juan Zhang, Fang Li, Jianyi Zhang, Xuegang Luo, Chang-Qi L. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus. Behavioural brain research. vol 265. 2014-11-13. PMID:24569010. |
these results suggested that the ee up-regulated mmp-9 levels within the hippocampus, which might facilitate the conversion of probdnf to bdnf, thereby contributing to the long lasting alterations of synaptic plasticity and behavior. |
2014-11-13 |
2023-08-12 |
rat |
| Jérémie Sibille, Ulrike Pannasch, Nathalie Rouac. Astroglial potassium clearance contributes to short-term plasticity of synaptically evoked currents at the tripartite synapse. The Journal of physiology. vol 592. issue 1. 2014-11-11. PMID:24081156. |
although astrocytes express ionic channels, neurotransmitter receptors and transporters to detect neuronal activity, the nature, plasticity and impact of the currents induced by neuronal activity on short-term synaptic plasticity remain elusive in hippocampal astrocytes. |
2014-11-11 |
2023-08-12 |
mouse |
| Tao Ma, Yiran Chen, Valerie Vingtdeux, Haitian Zhao, Benoit Viollet, Philippe Marambaud, Eric Klan. Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 36. 2014-11-10. PMID:25186765. |
inhibition of amp-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β. |
2014-11-10 |
2023-08-13 |
mouse |
| Na Liu, Bin Xue, Hua Xing, Lin Xu, Shan-Xiang Jian. [Dopamine-dependent long-term depression in hippocampus of rat induced by exposure to spatial novelty.]. Sheng li xue bao : [Acta physiologica Sinica]. vol 61. issue 6. 2014-11-08. PMID:20029683. |
these data provided important evidence that ltd may underlie certain forms of learning and memory and that dopamine participates in the synaptic plasticity in the process of hippocampal spatial information storage. |
2014-11-08 |
2023-08-12 |
rat |