| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xing-Ming Wang, Wei Pan, Ning Xu, Zhi-Qiang Zhou, Guang-Fen Zhang, Jin-Chun She. Environmental enrichment improves long-term memory impairment and aberrant synaptic plasticity by BDNF/TrkB signaling in nerve-injured mice. Neuroscience letters. vol 694. 2019-06-21. PMID:30496785. |
cci also induced the reduction of bdnf expression and synaptic plasticity impairments in the hippocampus, as represented by the dendritic spine density and postsynaptic density protein (psd)-95 reduction, and long-term potential (ltp) dysfunction. |
2019-06-21 |
2023-08-13 |
mouse |
| Xing-Ming Wang, Wei Pan, Ning Xu, Zhi-Qiang Zhou, Guang-Fen Zhang, Jin-Chun She. Environmental enrichment improves long-term memory impairment and aberrant synaptic plasticity by BDNF/TrkB signaling in nerve-injured mice. Neuroscience letters. vol 694. 2019-06-21. PMID:30496785. |
notably, ee can ameliorate the pain threshold and bdnf reduction, long-term memory deficits, and synaptic plasticity impairments in nerve-injured mice. |
2019-06-21 |
2023-08-13 |
mouse |
| Xing-Ming Wang, Wei Pan, Ning Xu, Zhi-Qiang Zhou, Guang-Fen Zhang, Jin-Chun She. Environmental enrichment improves long-term memory impairment and aberrant synaptic plasticity by BDNF/TrkB signaling in nerve-injured mice. Neuroscience letters. vol 694. 2019-06-21. PMID:30496785. |
in conclusion, ee improved the pain threshold reduction, long-term memory and synaptic plasticity deficits in nerve-injured mice; bdnf / trk b signaling may contribute to the relief of long-term memory and synaptic plasticity deficits induced by ee in nerve-injured mice. |
2019-06-21 |
2023-08-13 |
mouse |
| Camilla Lazzaretti, Grasielle Clotildes Kincheski, Pablo Pandolfo, Rachel Krolow, Ana Paula Toniazzo, Danusa Mar Arcego, Natividade de Sá Couto-Pereira, Fares Zeidán-Chuliá, Ben-Hur Neves de Oliveira, Diego Bertolini, Raquel Luísa Breunig, Andréa Kurek Ferreira, Janaína Kolling, Cassiana Siebert, Angela Teresinha Wyse, Tadeu Mello E Souza, Carla Dalma. Neonatal handling impairs intradimensional shift and alters plasticity markers in the medial prefrontal cortex of adult rats. Physiology & behavior. vol 197. 2019-06-11. PMID:30266584. |
we evaluated proteins related to synaptic plasticity (brain-derived neurotrophic factor [bdnf] and synaptophysin [syp]) as well as na |
2019-06-11 |
2023-08-13 |
rat |
| Bárbara Bruna, Pedro Lobos, Rodrigo Herrera-Molina, Cecilia Hidalgo, Andrea Paula-Lima, Tatiana Adasm. The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca Biochemical and biophysical research communications. vol 505. issue 1. 2019-05-28. PMID:30243728. |
the signaling pathways underlying bdnf-induced nrf2 hippocampal nuclear translocation involve ros, ryr-mediated ca the neurotrophin brain-derived neurotrophic factor (bdnf) induces complex neuronal signaling cascades that are critical for the cellular changes underlying synaptic plasticity. |
2019-05-28 |
2023-08-13 |
Not clear |
| Siamak Shahidi, Alireza Komaki, Reihaneh Sadeghian, Sara Soleimani As. Different doses of methamphetamine alter long-term potentiation, level of BDNF and neuronal apoptosis in the hippocampus of reinstated rats. The journal of physiological sciences : JPS. vol 69. issue 2. 2019-05-28. PMID:30680641. |
these results suggest that alterations in synaptic plasticity, expression of bdnf and neuronal apoptosis in the hippocampus has a vital role in the context-induced reinstatement of meth seeking. |
2019-05-28 |
2023-08-13 |
rat |
| Jun Shen, Yaqing Li, Chujie Qu, Linling Xu, Huimin Sun, Junjian Zhan. The enriched environment ameliorates chronic unpredictable mild stress-induced depressive-like behaviors and cognitive impairment by activating the SIRT1/miR-134 signaling pathway in hippocampus. Journal of affective disorders. vol 248. 2019-05-14. PMID:30716615. |
enriched environment (ee) showed a beneficial effect on depression and cognition by enhancing brain derived neurotrophic factor (bdnf) expression and synaptic plasticity. |
2019-05-14 |
2023-08-13 |
Not clear |
| Jun Shen, Yaqing Li, Chujie Qu, Linling Xu, Huimin Sun, Junjian Zhan. The enriched environment ameliorates chronic unpredictable mild stress-induced depressive-like behaviors and cognitive impairment by activating the SIRT1/miR-134 signaling pathway in hippocampus. Journal of affective disorders. vol 248. 2019-05-14. PMID:30716615. |
however, it is still not clearly understood whether an epigenetic mechanism is involved in the bdnf modulation and synaptic plasticity that occurs after ee treatment for the depressive-like behaviors and cognitive deficits elicited by cums. |
2019-05-14 |
2023-08-13 |
Not clear |
| Meng Zhang, Yating Zhai, Yaping Sun, Wenli Zhang, Qian Li, Darrell Brann, Ruimin Wan. Swimming improves cognitive reserve in ovariectomized rats and enhances neuroprotection after global cerebral ischemia. Brain research. vol 1692. 2019-05-08. PMID:29778778. |
we also examined the neuroprotective effect of swimming after global cerebral ischemia (gci) and explored the effect of swimming preconditioning on activation of the mapk cascade signaling pathway, synaptic proteins and brain-derived growth factor (bdnf) - all factors implicated in regulating synaptic plasticity and neuroprotection in the brain. |
2019-05-08 |
2023-08-13 |
rat |
| Pai-Kai Chiang, Feng-Yi Yan. A potential treatment of low intensity pulsed ultrasound on cavernous nerve injury for erectile dysfunction. Medical hypotheses. vol 122. 2019-05-06. PMID:30593410. |
brain-derived neurotrophic factor (bdnf) is a member of the neurotrophin family, which plays an important role in the survival of existing neurons, the differentiation of new neurons, and synaptic plasticity. |
2019-05-06 |
2023-08-13 |
Not clear |
| Zhenzhen Chen, Quan Hu, Qingfeng Xie, Shamin Wu, Qiongyi Pang, Meixia Liu, Yun Zhao, Fengxia Tu, Chan Liu, Xiang Che. Effects of Treadmill Exercise on Motor and Cognitive Function Recovery of MCAO Mice Through the Caveolin-1/VEGF Signaling Pathway in Ischemic Penumbra. Neurochemical research. vol 44. issue 4. 2019-04-26. PMID:30661230. |
these findings indicate that exercise improves angiogenesis, neurogenesis and synaptic plasticity to ameliorate motor and cognitive impairment after stroke partially through the caveolin-1/vegf pathway, which is associated with the coregulator factor, bdnf. |
2019-04-26 |
2023-08-13 |
mouse |
| Joe C Brague, Christine N Lenchur, Julia M Hayden, Rachel H Davidson, Kelly Corrigan, Garrett T Santini, Jennifer M Swan. BDNF infusion into the MPN mag is sufficient to restore copulatory behavior in the castrated Syrian hamster. Hormones and behavior. vol 102. 2019-04-25. PMID:29750970. |
as brain derived neurotrophic factor (bdnf) plays an integral role in regulating synaptic plasticity and gonadal steroids regulate the levels of bdnf, we hypothesize that bdnf may mediate the effects of gonadal hormones on copulatory behavior. |
2019-04-25 |
2023-08-13 |
Not clear |
| Anastacia Y Kudinova, Terrence Deak, Molly M Deak, Brandon E Gib. Circulating Levels of Brain-Derived Neurotrophic Factor and History of Suicide Attempts in Women. Suicide & life-threatening behavior. vol 49. issue 1. 2019-04-15. PMID:28960421. |
a growing body of research examining biological factors associated with suicidal behaviors highlights the role of brain-derived neurotropic factor (bdnf), involved in neurogenesis and synaptic plasticity. |
2019-04-15 |
2023-08-13 |
Not clear |
| Paul D Loprinzi, Emily Frit. A brief primer on the mediational role of BDNF in the exercise-memory link. Clinical physiology and functional imaging. vol 39. issue 1. 2019-04-09. PMID:29719116. |
as discussed herein, bdnf may influence memory via bdnf-induced alterations in membrane receptor expression and translocation, as well as activating several pathways (plc-y, pi3k, erk) that act together to facilitate cellular effects that influence synaptic plasticity. |
2019-04-09 |
2023-08-13 |
human |
| P Zanos, T D Goul. Mechanisms of ketamine action as an antidepressant. Molecular psychiatry. vol 23. issue 4. 2019-04-04. PMID:29532791. |
we also discuss links between ketamine's antidepressant actions and downstream mechanisms regulating synaptic plasticity, including brain-derived neurotrophic factor (bdnf), eukaryotic elongation factor 2 (eef2), mechanistic target of rapamycin (mtor) and glycogen synthase kinase-3 (gsk-3). |
2019-04-04 |
2023-08-13 |
Not clear |
| Francis S Lee, Barbara L Hempstea. New Roles for an Ancient Factor. Trends in neurosciences. vol 41. issue 11. 2019-04-04. PMID:30219601. |
in 1996, hyejin kang and erin schuman, in search of new functions for the secreted growth factor brain-derived neurotrophic factor (bdnf), identified the protein synthesis requirement of bdnf in regulating synaptic plasticity. |
2019-04-04 |
2023-08-13 |
Not clear |
| Hui Chen, Larbi Amazit, Marc Lombès, Damien Le Menue. Crosstalk Between Glucocorticoid Receptor and Early-growth Response Protein 1 Accounts for Repression of Brain-derived Neurotrophic Factor Transcript 4 Expression. Neuroscience. vol 399. 2019-03-11. PMID:30578973. |
the brain-derived neurotrophic factor (bdnf) is a key player in brain functions such as synaptic plasticity, stress, and behavior. |
2019-03-11 |
2023-08-13 |
Not clear |
| Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Qinjie Li, Ya Mia. Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30365051. |
it is not known whether brain‑derived neurotrophic factor (bdnf) protects hippocampal neurons from high glucose‑induced apoptosis and/or synaptic plasticity dysfunction. |
2019-03-05 |
2023-08-13 |
rat |
| Wenping Zhang, Yuqiang Shi, Yanxi Peng, Ling Zhong, Shuang Zhu, Wenbo Zhang, Shao-Jun Tan. Neuron activity-induced Wnt signaling up-regulates expression of brain-derived neurotrophic factor in the pain neural circuit. The Journal of biological chemistry. vol 293. issue 40. 2019-03-04. PMID:30139740. |
brain-derived neurotrophic factor (bdnf) is a master regulator of synaptic plasticity in various neural circuits of the mammalian central nervous system. |
2019-03-04 |
2023-08-13 |
Not clear |
| Stine Normann Hansen, David Højland Ipsen, Anne Marie Schou-Pedersen, Jens Lykkesfeldt, Pernille Tveden-Nybor. Long term Westernized diet leads to region-specific changes in brain signaling mechanisms. Neuroscience letters. vol 676. 2019-02-22. PMID:29655945. |
here we investigate the effects of dyslipidemia induced by two high fat diets with or without high sucrose on hippocampal and frontal cortical oxidative stress, brain-derived neurotrophic factor (bdnf) and down-stream markers of synaptic plasticity, as well as alterations in monoaminergic neurotransmitter levels. |
2019-02-22 |
2023-08-13 |
Not clear |