| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna G McGrath, Lisa A Brian. A potential role for microglia in stress- and drug-induced plasticity in the nucleus accumbens: A mechanism for stress-induced vulnerability to substance use disorder. Neuroscience and biobehavioral reviews. vol 107. 2020-08-31. PMID:31550452. |
this review focuses on three components of synaptic plasticity: spine density, brain-derived neurotrophic factor (bdnf) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor expression. |
2020-08-31 |
2023-08-13 |
Not clear |
| Dharani Keyan, Richard A Bryan. The capacity for acute exercise to modulate emotional memories: A review of findings and mechanisms. Neuroscience and biobehavioral reviews. vol 107. 2020-08-31. PMID:31562922. |
central to the relationship between acute exercise and fear memory is brain derived neurotrophic factor (bdnf), which is augmented following acute exercise and is involved in synaptic plasticity and associative learning and memory. |
2020-08-31 |
2023-08-13 |
human |
| Cynthia Shannon Weickert, Cynthia H Lee, Rhoshel K Lenroot, Jason Bruggemann, Cherrie Galletly, Dennis Liu, Ryan Balzan, Anilkumar Pillai, Peter Buckley, Thomas W Weicker. Increased plasma Brain-Derived Neurotrophic Factor (BDNF) levels in females with schizophrenia. Schizophrenia research. vol 209. 2020-08-28. PMID:31088701. |
brain-derived neurotrophic factor (bdnf) acts as a critical regulator of synaptogenesis and synaptic plasticity. |
2020-08-28 |
2023-08-13 |
Not clear |
| Eli-Eelika Esvald, Jürgen Tuvikene, Alex Sirp, Sudarshan Patil, Clive R Bramham, Tõnis Timmus. CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 7. 2020-08-19. PMID:31915257. |
bdnf signaling via its transmembrane receptor trkb has an important role in neuronal survival, differentiation, and synaptic plasticity. |
2020-08-19 |
2023-08-13 |
rat |
| Xiao-Ying Lin, Ying Cui, Lei Wang, Wen Che. Chronic exercise buffers the cognitive dysfunction and decreases the susceptibility to seizures in PTZ-treated rats. Epilepsy & behavior : E&B. vol 98. issue Pt A. 2020-07-27. PMID:31377659. |
the levels of synaptic-related proteins including psd95 (postsynaptic density 95), synapsin, glua1, and bdnf (brain-derived neurotrophic factor) were measured to evaluate the hippocampal synaptic plasticity. |
2020-07-27 |
2023-08-13 |
rat |
| Mingxing Li, Xuejiao Sun, Qian Li, Yong Li, Can Luo, Hailong Huang, Jing Chen, Chenzi Gong, Yajie Li, Yifeng Zheng, Song Zhang, Xiaolin Huang, Hong Che. Fucoidan exerts antidepressant-like effects in mice via regulating the stability of surface AMPARs. Biochemical and biophysical research communications. vol 521. issue 2. 2020-07-27. PMID:31668812. |
interestingly, chronic fucoidan administration not only dose-dependently reduced stress-induced depressive-like behaviors in the tst, fst, sucrose preference test (spt), and novelty-suppressed feeding test (nsft), but also alleviated the downregulation of brain-derived neurotrophic factor (bdnf)-dependent synaptic plasticity via inhibiting caspase-1-mediated inflammation in the hippocampus of mice. |
2020-07-27 |
2023-08-13 |
mouse |
| Henry L Hallock, Henry M Quillian, Yishan Mai, Kristen R Maynard, Julia L Hill, Keri Martinowic. Manipulation of a genetically and spatially defined sub-population of BDNF-expressing neurons potentiates learned fear and decreases hippocampal-prefrontal synchrony in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 13. 2020-07-08. PMID:31170726. |
brain-derived neurotrophic factor (bdnf) signaling regulates synaptic plasticity in the hippocampus (hc) and prefrontal cortex (pfc), and has been extensively linked with fear memory expression in rodents. |
2020-07-08 |
2023-08-13 |
mouse |
| Jaclyn M Obermeyer, Anup Tuladhar, Samantha L Payne, Eric Ho, Cindi M Morshead, Molly S Shoiche. Local Delivery of Brain-Derived Neurotrophic Factor Enables Behavioral Recovery and Tissue Repair in Stroke-Injured Rats. Tissue engineering. Part A. vol 25. issue 15-16. 2020-05-22. PMID:30612516. |
we demonstrate that when delivered epicortically to a rat model of stroke, this composite allows bdnf to diffuse into the brain, resulting in enhanced behavioral recovery and synaptic plasticity in the contralesional hemisphere. |
2020-05-22 |
2023-08-13 |
rat |
| Eboni I Lance, Emily Barron-Casella, Allen D Everett, James F Casell. Brain-derived neurotrophic factor levels in pediatric sickle cell disease. Pediatric blood & cancer. vol 67. issue 2. 2020-04-22. PMID:31736231. |
brain-derived neurotrophic factor (bdnf) is a nerve growth factor associated with neuronal survival, synaptic plasticity, elevated transcranial doppler (tcd) velocities and increased risk of stroke in patients with scd. |
2020-04-22 |
2023-08-13 |
human |
| Siamak Shahidi, Omid Mehrpour, Reihaneh Sadeghian, Sara Soleimani Asl, Alireza Komak. Alteration level of hippocampus BDNF expression and long-term potentiation upon microinjection of BRL15572 hydrochloride in a rat model of methamphetamine relapse. Brain research bulletin. vol 148. 2020-04-17. PMID:30904722. |
methamphetamine (meth) relapse affects the function of the serotonergic system, which this system important for synaptic plasticity and brain-derived neurotrophic factor (bdnf) level. |
2020-04-17 |
2023-08-13 |
rat |
| Sujin Kim, Ji-Young Choi, Sohee Moon, Dong-Ho Park, Hyo-Bum Kwak, Ju-Hee Kan. Roles of myokines in exercise-induced improvement of neuropsychiatric function. Pflugers Archiv : European journal of physiology. vol 471. issue 3. 2020-04-09. PMID:30627775. |
among several myokines, brain-derived neurotrophic factor (bdnf) is the most studied myokine that regulates adult neurogenesis and synaptic plasticity. |
2020-04-09 |
2023-08-13 |
Not clear |
| Jie Xiang, Zhi-Hao Wang, Eun Hee Ahn, Xia Liu, Shan-Ping Yu, Fredric P Manfredsson, Ivette M Sandoval, Gong Ju, Shengxi Wu, Keqiang Y. Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 18. 2020-03-25. PMID:31004063. |
bdnf, an essential trophic factor implicated in synaptic plasticity and neuronal survival, is reduced in alzheimer's disease (ad). |
2020-03-25 |
2023-08-13 |
Not clear |
| Pasquale Di Carlo, Giovanna Punzi, Gianluca Ursin. Brain-derived neurotrophic factor and schizophrenia. Psychiatric genetics. vol 29. issue 5. 2020-02-26. PMID:31465000. |
the brain-derived neurotrophic factor (bdnf) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. |
2020-02-26 |
2023-08-13 |
human |
| Francesca Caracci, Joyce Harary, Sherry Simkovic, Giulio Maria Pasinett. Grape-Derived Polyphenols Ameliorate Stress-Induced Depression by Regulating Synaptic Plasticity. Journal of agricultural and food chemistry. vol 68. issue 7. 2020-02-26. PMID:31532659. |
elevated levels of proinflammatory cytokines and reduced bdnf levels lead to impaired synaptic plasticity mechanisms that contribute to the pathophysiology of mdd. |
2020-02-26 |
2023-08-13 |
Not clear |
| Francesca Caracci, Joyce Harary, Sherry Simkovic, Giulio Maria Pasinett. Grape-Derived Polyphenols Ameliorate Stress-Induced Depression by Regulating Synaptic Plasticity. Journal of agricultural and food chemistry. vol 68. issue 7. 2020-02-26. PMID:31532659. |
there is accumulating evidence that the administration of polyphenols at doses ranging from 5 to 180 mg/kg of body weight can normalize elevated levels of proinflammatory cytokines and abnormal levels of bdnf and, thus, restore impaired synaptic plasticity mechanisms that mediate depressive behavior in animal models of stress. |
2020-02-26 |
2023-08-13 |
Not clear |
| Paul A Lapchak, Paul D Boitano, Rene Bombien, Douglas J Cook, Sarina Doyan, Jacqueline M Lara, David R Schuber. CNB-001, a pleiotropic drug is efficacious in embolized agyrencephalic New Zealand white rabbits and ischemic gyrencephalic cynomolgus monkeys. Experimental neurology. vol 313. 2020-02-24. PMID:30521790. |
mechanistically, cnb-001 inhibits human 5- and 15-lipoxygenase in vitro, and can attenuate ischemia-induced inflammatory markers, and oxidative stress markers, while potentially promoting synaptic plasticity mediated by enhanced brain-derived neurotrophic factor (bdnf). |
2020-02-24 |
2023-08-13 |
human |
| Fen Xue, Shan-Shan Xue, Ling Liu, Han-Fei Sang, Quan-Rui Ma, Qing-Rong Tan, Hua-Ning Wang, Cui-Hong Zhou, Zheng-Wu Pen. Early intervention with electroacupuncture prevents PTSD-like behaviors in rats through enhancing hippocampal endocannabinoid signaling. Progress in neuro-psychopharmacology & biological psychiatry. vol 93. 2020-02-14. PMID:30946940. |
the results showed that early ea intervention improved hippocampal synaptic plasticity and ameliorated ptsd-like behaviors and also increased expression of bdnf, daglα and cb1r. |
2020-02-14 |
2023-08-13 |
rat |
| Jo Wrigglesworth, Joanne Ryan, Nandita Vijayakumar, Sarah Whittl. Brain-derived neurotrophic factor DNA methylation mediates the association between neighborhood disadvantage and adolescent brain structure. Psychiatry research. Neuroimaging. vol 285. 2020-02-11. PMID:30771753. |
this study investigated whether dna methylation of the brain-derived neurotrophic factor (bdnf, which plays a key role in synaptic plasticity), mediated the association between neighborhood disadvantage and thickness of the pfc in adolescents. |
2020-02-11 |
2023-08-13 |
Not clear |
| Francesco Tomassoni-Ardori, Gianluca Fulgenzi, Jodi Becker, Colleen Barrick, Mary Ellen Palko, Skyler Kuhn, Vishal Koparde, Maggie Cam, Sudhirkumar Yanpallewar, Shalini Oberdoerffer, Lino Tessaroll. Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels. eLife. vol 8. 2020-01-31. PMID:31429825. |
brain-derived neurotrophic factor (bdnf) is a potent modulator of brain synaptic plasticity. |
2020-01-31 |
2023-08-13 |
Not clear |
| Julia Leschik, Robert Eckenstaler, Thomas Endres, Thomas Munsch, Elke Edelmann, Karin Richter, Oliver Kobler, Klaus-Dieter Fischer, Werner Zuschratter, Tanja Brigadski, Beat Lutz, Volkmar Lessman. Prominent Postsynaptic and Dendritic Exocytosis of Endogenous BDNF Vesicles in BDNF-GFP Knock-in Mice. Molecular neurobiology. vol 56. issue 10. 2020-01-30. PMID:30929164. |
brain-derived neurotrophic factor (bdnf) is a secreted messenger molecule that is crucial for neuronal function and induction of synaptic plasticity. |
2020-01-30 |
2023-08-13 |
mouse |