| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gina Cavaliere, Giovanna Trinchese, Eduardo Penna, Fabiano Cimmino, Claudio Pirozzi, Adriano Lama, Chiara Annunziata, Angela Catapano, Giuseppina Mattace Raso, Rosaria Meli, Marcellino Monda, Giovanni Messina, Christian Zammit, Marianna Crispino, Maria Pina Mollic. High-Fat Diet Induces Neuroinflammation and Mitochondrial Impairment in Mice Cerebral Cortex and Synaptic Fraction. Frontiers in cellular neuroscience. vol 13. 2020-09-28. PMID:31798417. |
these alterations parallel with modulation of bdnf, a brain key signaling molecule that is linking synaptic plasticity and energy metabolism. |
2020-09-28 |
2023-08-13 |
mouse |
| Fabrizio Sanna, Jessica Bratzu, Maria Pina Serra, Damiana Leo, Marina Quartu, Marianna Boi, Stefano Espinoza, Raul R Gainetdinov, Maria Rosaria Melis, Antonio Argiola. Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32372926. |
markers of neurotropism (bdnf, trkb), neural activation (Δ-fosb), functional (arc and psa-ncam) and structural synaptic plasticity (synaptophysin, syntaxin-3, psd-95) were also measured in the ventral tegmental area (vta), acb (shell and core) and medial prefrontal cortex (mpfc) by western blot assays. |
2020-09-28 |
2023-08-13 |
rat |
| Brian M Kopec, Liqin Zhao, Eduardo Rosa-Molinar, Teruna J Siahaa. Non-invasive Brain Delivery and Efficacy of BDNF in APP/PS1 Transgenic Mice as a Model of Alzheimer's Disease. Medical research archives. vol 8. issue 2. 2020-09-28. PMID:32551362. |
in summary, adtc5 can deliver bdnf into the brains of app/ps1 mice and the activity of bdnf in improving cognitive function was likely due to improvement in synaptic plasticity via ng2 glia cells and not by reducing the plaque load. |
2020-09-28 |
2023-08-13 |
mouse |
| Ulyana Lalo, Alexander Bogdanov, Guy W Moss, Yuriy Pankrato. Astroglia-Derived BDNF and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity. Brain sciences. vol 10. issue 7. 2020-09-28. PMID:32708382. |
astroglia-derived bdnf and msk-1 mediate experience- and diet-dependent synaptic plasticity. |
2020-09-28 |
2023-08-13 |
mouse |
| Ulyana Lalo, Alexander Bogdanov, Guy W Moss, Yuriy Pankrato. Astroglia-Derived BDNF and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity. Brain sciences. vol 10. issue 7. 2020-09-28. PMID:32708382. |
to elucidate a role for astroglia-derived bdnf in homeostatic synaptic plasticity in the aging brain, we explored the experience- and diet-related alterations of synaptic transmission and plasticity in transgenic mice with impairment of the bdnf/msk1 pathway (msk1 kinase dead knock-in mice, msk1 kd) and impairment of glial exocytosis (dnsnare mice). |
2020-09-28 |
2023-08-13 |
mouse |
| Sara Cocco, Marco Rinaudo, Salvatore Fusco, Valentina Longo, Katia Gironi, Pietro Renna, Giuseppe Aceto, Alessia Mastrodonato, Domenica Donatella Li Puma, Maria Vittoria Podda, Claudio Grass. Plasma BDNF Levels Following Transcranial Direct Current Stimulation Allow Prediction of Synaptic Plasticity and Memory Deficits in 3×Tg-AD Mice. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32719795. |
plasma bdnf levels following transcranial direct current stimulation allow prediction of synaptic plasticity and memory deficits in 3×tg-ad mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Diana Kimono, Dipro Bose, Ratanesh K Seth, Ayan Mondal, Punnag Saha, Patricia Janulewicz, Kimberly Sullivan, Stephen Lasley, Ronnie Horner, Nancy Klimas, Saurabh Chatterje. Host Neuroscience insights. vol 15. 2020-09-28. PMID:32832901. |
in this study, we used a rodent model of gwi to investigate the persistence of microbiome alterations, resultant chronic inflammation, and its effect on neurotrophic and synaptic plasticity marker bdnf. |
2020-09-28 |
2023-08-13 |
Not clear |
| Ava Modirzadeh Tehrani, Mahdi Eskandarian Boroujeni, Abbas Aliaghaei, Mohammad Ali Hosseinpour Feizi, Reza Safaralizade. Methamphetamine induces neurotoxicity-associated pathways and stereological changes in prefrontal cortex. Neuroscience letters. vol 712. 2020-09-23. PMID:31491463. |
besides, the protein levels of brain derived neurotrophic factor (bdnf) and glial fibrillary acidic protein (gfap) as markers of synaptic plasticity and gliosis were inspected, respectively. |
2020-09-23 |
2023-08-13 |
rat |
| Alessandro Moro, Geeske M van Woerden, Ruud F Toonen, Matthijs Verhag. CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles. PLoS biology. vol 18. issue 8. 2020-09-17. PMID:32776935. |
ca2+/calmodulin-dependent kinase ii (camkii) regulates synaptic plasticity in multiple ways, supposedly including the secretion of neuromodulators like brain-derived neurotrophic factor (bdnf). |
2020-09-17 |
2023-08-13 |
mouse |
| Aarti Nagayach, Anshuman Singh, Alfred I Gelle. Delivery of different genes into presynaptic and postsynaptic neocortical neurons connected by a BDNF-TrkB synapse. Brain research. vol 1712. 2020-09-11. PMID:30710509. |
brain-derived neurotrophic factor (bdnf) signaling through trkb receptors has important roles in synapse formation, synaptic plasticity, learning, and specific diseases. |
2020-09-11 |
2023-08-13 |
rat |
| Ying Yu, Dan Xu, Siyuan Cheng, Li Zhang, Zhaokun Shi, Jun Qin, Zhaohui Zhang, Hui Wan. Prenatal ethanol exposure enhances the susceptibility to depressive behavior of adult offspring rats fed a high‑fat diet by affecting BDNF‑associated pathway. International journal of molecular medicine. vol 45. issue 2. 2020-09-11. PMID:31894308. |
multigene rt‑qpcr also revealed that the mrna expression levels for bdnf pathway‑associated genes and synaptic plasticity genes were decreased in the hippocampus of fetal offspring rats in the pee group. |
2020-09-11 |
2023-08-13 |
rat |
| Nektarios Tavernaraki. Regulation and Roles of Autophagy in the Brain. Advances in experimental medicine and biology. vol 1195. 2020-09-11. PMID:32468455. |
our results establish autophagy as a pivotal component of bdnf signaling, which is essential for bdnf-induced synaptic plasticity. |
2020-09-11 |
2023-08-13 |
mouse |
| Zeyi Huang, Daichao Wu, Xilin Qu, Meixiang Li, Ju Zou, Sijie Ta. BDNF and nicotine dependence: associations and potential mechanisms. Reviews in the neurosciences. 2020-09-05. PMID:32887210. |
brain-derived neurotrophic factor (bdnf) is the most prevalent growth factor in the brain, which regulates neuron survival, differentiation, and synaptic plasticity, mainly through binding to the high affinity receptor tyrosine kinase receptor b (trkb). |
2020-09-05 |
2023-08-13 |
Not clear |
| Anna G McGrath, Lisa A Brian. A potential role for microglia in stress- and drug-induced plasticity in the nucleus accumbens: A mechanism for stress-induced vulnerability to substance use disorder. Neuroscience and biobehavioral reviews. vol 107. 2020-08-31. PMID:31550452. |
this review focuses on three components of synaptic plasticity: spine density, brain-derived neurotrophic factor (bdnf) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor expression. |
2020-08-31 |
2023-08-13 |
Not clear |
| Dharani Keyan, Richard A Bryan. The capacity for acute exercise to modulate emotional memories: A review of findings and mechanisms. Neuroscience and biobehavioral reviews. vol 107. 2020-08-31. PMID:31562922. |
central to the relationship between acute exercise and fear memory is brain derived neurotrophic factor (bdnf), which is augmented following acute exercise and is involved in synaptic plasticity and associative learning and memory. |
2020-08-31 |
2023-08-13 |
human |
| Cynthia Shannon Weickert, Cynthia H Lee, Rhoshel K Lenroot, Jason Bruggemann, Cherrie Galletly, Dennis Liu, Ryan Balzan, Anilkumar Pillai, Peter Buckley, Thomas W Weicker. Increased plasma Brain-Derived Neurotrophic Factor (BDNF) levels in females with schizophrenia. Schizophrenia research. vol 209. 2020-08-28. PMID:31088701. |
brain-derived neurotrophic factor (bdnf) acts as a critical regulator of synaptogenesis and synaptic plasticity. |
2020-08-28 |
2023-08-13 |
Not clear |
| Eli-Eelika Esvald, Jürgen Tuvikene, Alex Sirp, Sudarshan Patil, Clive R Bramham, Tõnis Timmus. CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 7. 2020-08-19. PMID:31915257. |
bdnf signaling via its transmembrane receptor trkb has an important role in neuronal survival, differentiation, and synaptic plasticity. |
2020-08-19 |
2023-08-13 |
rat |
| Xiao-Ying Lin, Ying Cui, Lei Wang, Wen Che. Chronic exercise buffers the cognitive dysfunction and decreases the susceptibility to seizures in PTZ-treated rats. Epilepsy & behavior : E&B. vol 98. issue Pt A. 2020-07-27. PMID:31377659. |
the levels of synaptic-related proteins including psd95 (postsynaptic density 95), synapsin, glua1, and bdnf (brain-derived neurotrophic factor) were measured to evaluate the hippocampal synaptic plasticity. |
2020-07-27 |
2023-08-13 |
rat |
| Mingxing Li, Xuejiao Sun, Qian Li, Yong Li, Can Luo, Hailong Huang, Jing Chen, Chenzi Gong, Yajie Li, Yifeng Zheng, Song Zhang, Xiaolin Huang, Hong Che. Fucoidan exerts antidepressant-like effects in mice via regulating the stability of surface AMPARs. Biochemical and biophysical research communications. vol 521. issue 2. 2020-07-27. PMID:31668812. |
interestingly, chronic fucoidan administration not only dose-dependently reduced stress-induced depressive-like behaviors in the tst, fst, sucrose preference test (spt), and novelty-suppressed feeding test (nsft), but also alleviated the downregulation of brain-derived neurotrophic factor (bdnf)-dependent synaptic plasticity via inhibiting caspase-1-mediated inflammation in the hippocampus of mice. |
2020-07-27 |
2023-08-13 |
mouse |
| Henry L Hallock, Henry M Quillian, Yishan Mai, Kristen R Maynard, Julia L Hill, Keri Martinowic. Manipulation of a genetically and spatially defined sub-population of BDNF-expressing neurons potentiates learned fear and decreases hippocampal-prefrontal synchrony in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 13. 2020-07-08. PMID:31170726. |
brain-derived neurotrophic factor (bdnf) signaling regulates synaptic plasticity in the hippocampus (hc) and prefrontal cortex (pfc), and has been extensively linked with fear memory expression in rodents. |
2020-07-08 |
2023-08-13 |
mouse |