| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katherine S Damme, Christina B Young, Robin Nussloc. Elevated nucleus accumbens structural connectivity associated with proneness to hypomania: a reward hypersensitivity perspective. Social cognitive and affective neuroscience. vol 12. issue 6. 2018-04-13. PMID:28338785. |
in line with this perspective, individuals with bipolar disorder display elevated activation in a cortico-striatal reward circuit including the nucleus accumbens (nacc) and medial orbitofrontal cortex (mofc). |
2018-04-13 |
2023-08-13 |
human |
| Xiaoluan Xia, Lingzhong Fan, Chen Cheng, Simon B Eickhoff, Junjie Chen, Haifang Li, Tianzi Jian. Multimodal connectivity-based parcellation reveals a shell-core dichotomy of the human nucleus accumbens. Human brain mapping. vol 38. issue 8. 2018-04-02. PMID:28548226. |
the subdifferentiation of the nucleus accumbens (nac) has been extensively studied using neuroanatomy and histochemistry, yielding a well-accepted dichotomic shell/core architecture that reflects dissociable roles, such as in reward and aversion, respectively. |
2018-04-02 |
2023-08-13 |
human |
| Linnea Granholm, Aniruddah Todkar, Sofia Bergman, Kent Nilsson, Erika Comasco, Ingrid Nylande. The expression of opioid genes in non-classical reward areas depends on early life conditions and ethanol intake. Brain research. vol 1668. 2018-03-28. PMID:28511993. |
recent studies show that the classical reward areas nucleus accumbens and ventral tegmental area are less affected by early life stress whereas endogenous opioids in non-classical areas, e.g. |
2018-03-28 |
2023-08-13 |
rat |
| Ashley E Lepack, Rosemary C Bagot, Catherine J Peña, Yong-Hwee E Loh, Lorna A Farrelly, Yang Lu, Samuel K Powell, Zachary S Lorsch, Orna Issler, Hannah M Cates, Carol A Tamminga, Henrik Molina, Li Shen, Eric J Nestler, C David Allis, Ian Maz. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 44. 2018-03-26. PMID:27791098. |
here, we demonstrate a role for increased h3.3 dynamics in the nucleus accumbens (nac)-a key limbic brain reward region-in the regulation of aberrant social stress-mediated gene expression and the precipitation of depressive-like behaviors in mice. |
2018-03-26 |
2023-08-13 |
mouse |
| Jian Feng, Catherine J Pena, Immanuel Purushothaman, Olivia Engmann, Deena Walker, Amber N Brown, Orna Issler, Marie Doyle, Eileen Harrigan, Ezekiell Mouzon, Vincent Vialou, Li Shen, Meelad M Dawlaty, Rudolf Jaenisch, Eric J Nestle. Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28074830. |
we applied chronic social defeat stress, an ethologically validated mouse model of depression-like behaviors, and examined tet1 expression changes in nucleus accumbens (nac), a key brain reward region. |
2018-03-23 |
2023-08-13 |
mouse |
| Saki Minami, Hiroshi Satoyoshi, Soichiro Ide, Takeshi Inoue, Mitsuhiro Yoshioka, Masabumi Minam. Suppression of reward-induced dopamine release in the nucleus accumbens in animal models of depression: Differential responses to drug treatment. Neuroscience letters. vol 650. 2018-03-19. PMID:28432029. |
we investigated reward (30% sucrose intake)-induced da release in the nucleus accumbens (nac) and the effect of chronic treatment with the antidepressant escitalopram (5mg/kg, intraperitoneally twice daily for 3 weeks) in two animal models of depression. |
2018-03-19 |
2023-08-13 |
Not clear |
| Kenneth Blum, Thomas Simpatico, Marcelo Febo, Chris Rodriquez, Kristina Dushaj, Mona Li, Eric R Braverman, Zsolt Demetrovics, Marlene Oscar-Berman, Rajendra D Badgaiya. Hypothesizing Music Intervention Enhances Brain Functional Connectivity Involving Dopaminergic Recruitment: Common Neuro-correlates to Abusable Drugs. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27246565. |
fmri data has shown that music listening intensely modifies mesolimbic structural changes responsible for reward processing (e.g., nucleus accumbens [nac]) and may control the emotional stimuli's effect on autonomic and physiological responses (e.g., hypothalamus). |
2018-03-09 |
2023-08-13 |
Not clear |
| Samuel W Hawes, Rajpreet Chahal, Michael N Hallquist, David J Paulsen, Charles F Geier, Beatriz Lun. Modulation of reward-related neural activation on sensation seeking across development. NeuroImage. vol 147. 2018-03-06. PMID:27956207. |
although some have suggested that increased neural responsivity to reward within the ventral striatum (e.g., nucleus accumbens) may drive sensation seeking behaviors, few studies have examined the neural mechanisms associated with stable individual differences in sensation seeking across development. |
2018-03-06 |
2023-08-13 |
Not clear |
| Samuel W Hawes, Rajpreet Chahal, Michael N Hallquist, David J Paulsen, Charles F Geier, Beatriz Lun. Modulation of reward-related neural activation on sensation seeking across development. NeuroImage. vol 147. 2018-03-06. PMID:27956207. |
results indicated that during early adolescence (~ages 10-12), increased reactivity to reward within the nucleus accumbens (nacc) was associated with lower levels of sensation seeking across a three-year follow-up. |
2018-03-06 |
2023-08-13 |
Not clear |
| Olivia M Maynard, Jonathan C W Brooks, Marcus R Munafò, Ute Leonard. Neural mechanisms underlying visual attention to health warnings on branded and plain cigarette packs. Addiction (Abingdon, England). vol 112. issue 4. 2018-02-26. PMID:27886656. |
to (1) test if activation in brain regions related to reward (nucleus accumbens) and emotion (amygdala) differ when branded and plain packs of cigarettes are viewed, (2) test whether these activation patterns differ by smoking status and (3) examine whether activation patterns differ as a function of visual attention to health warning labels on cigarette packs. |
2018-02-26 |
2023-08-13 |
Not clear |
| Ana M Fiallos, Sarah J Bricault, Lili X Cai, Hermoon A Worku, Matthew T Colonnese, Gil G Westmeyer, Alan Jasanof. Reward magnitude tracking by neural populations in ventral striatum. NeuroImage. vol 146. 2018-02-14. PMID:27789262. |
the largest and most reliable focus of reward magnitude tracking was observed in the shell region of the nucleus accumbens (nac). |
2018-02-14 |
2023-08-13 |
Not clear |
| S J Baracz, L M Parker, A S Suraev, N A Everett, A K Goodchild, I S McGregor, J L Cornis. Chronic Methamphetamine Self-Administration Dysregulates Oxytocin Plasma Levels and Oxytocin Receptor Fibre Density in the Nucleus Accumbens Core and Subthalamic Nucleus of the Rat. Journal of neuroendocrinology. vol 28. issue 4. 2018-02-08. PMID:26563756. |
recent findings have implicated the nucleus accumbens (nac) core and subthalamic nucleus (sth) in oxytocin modulation of acute meth reward and relapse to meth-seeking behaviour. |
2018-02-08 |
2023-08-13 |
rat |
| Maria Vrettou, Linnea Granholm, Aniruddha Todkar, Kent W Nilsson, Åsa Wallén-Mackenzie, Ingrid Nylander, Erika Comasc. Ethanol affects limbic and striatal presynaptic glutamatergic and DNA methylation gene expression in outbred rats exposed to early-life stress. Addiction biology. vol 22. issue 2. 2018-01-30. PMID:26610727. |
brain regions of interest were the ventral tegmental area (vta), nucleus accumbens (acb), medial prefrontal cortex (mpfc) and dorsal striatum (dstr), all involved in mediating aspects of ethanol reward. |
2018-01-30 |
2023-08-13 |
rat |
| Yo Oishi, Qi Xu, Lu Wang, Bin-Jia Zhang, Koji Takahashi, Yohko Takata, Yan-Jia Luo, Yoan Cherasse, Serge N Schiffmann, Alban de Kerchove d'Exaerde, Yoshihiro Urade, Wei-Min Qu, Zhi-Li Huang, Michael Lazaru. Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. Nature communications. vol 8. issue 1. 2018-01-29. PMID:28963505. |
previous studies suggest that adenosine has a role affecting behavioural arousal in the nucleus accumbens (nac), a brain area critical for reinforcement and reward. |
2018-01-29 |
2023-08-13 |
mouse |
| S Nakanishi, T Hikida, S Yawat. Distinct dopaminergic control of the direct and indirect pathways in reward-based and avoidance learning behaviors. Neuroscience. vol 282. 2018-01-26. PMID:24769227. |
the nucleus accumbens (nac) plays a pivotal role in reward and aversive learning and learning flexibility. |
2018-01-26 |
2023-08-13 |
mouse |
| Wolfram Schult. Reward functions of the basal ganglia. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 7. 2018-01-23. PMID:26838982. |
this review describes the reward functions of three brain structures that are major components of the basal ganglia or are closely associated with the basal ganglia, namely midbrain dopamine neurons, pedunculopontine nucleus, and striatum (caudate nucleus, putamen, nucleus accumbens). |
2018-01-23 |
2023-08-13 |
Not clear |
| Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27711046. |
recent research shows dysregulation in epigenetic regulatory mechanisms, particularly the transcriptionally repressive di- and tri-methylation of histone 3 lysine 9 (h3k9me2/me3) in nucleus accumbens (nac), a critical region of the reward pathway involved in the development of anhedonia, the hallmark of depression. |
2018-01-19 |
2023-08-13 |
mouse |
| Zheng-Xiong Xi, Rui Song, Xia Li, Guan-Yi Lu, Xiao-Qing Peng, Yi He, Guo-Hua Bi, Siyuan Peter Sheng, Hong-Ju Yang, Haiying Zhang, Jin Li, Mark Froimowitz, Eliot L Gardne. CTDP-32476: A Promising Agonist Therapy for Treatment of Cocaine Addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27534265. |
systemic administration of ctdp-32476 alone produced a slow-onset, long-lasting increase in extracellular nucleus accumbens da, locomotion, and brain-stimulation reward. |
2018-01-16 |
2023-08-13 |
rat |
| Michael P Saddoris, Jonathan A Sugam, Regina M Carell. Prior Cocaine Experience Impairs Normal Phasic Dopamine Signals of Reward Value in Accumbens Shell. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27604567. |
to quantify this, we voltammetrically measured real-time dopamine release in the nucleus accumbens (nac) core or shell while rats received unsignaled deliveries of either a small (1 pellet) or large (2 pellets) reward. |
2018-01-16 |
2023-08-13 |
rat |
| Hai-Jun Wang, Hong-Tao Yang, Wei Che. Swimming exercise reduces preference for a high-fat diet by increasing insulin sensitivity in C57BL/6 mice. Neuroreport. vol 28. issue 1. 2018-01-10. PMID:27893609. |
taken together, these results suggest that swimming exercise regulates the dopaminergic reward system to decrease high-fat diet intake, thereby controlling body weight to prevent obesity, in a manner likely mediated by increased insulin signal transduction in the nucleus accumbens. |
2018-01-10 |
2023-08-13 |
mouse |