| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amanda L Sharpe, Erika Varela, Michael J Beckstea. Systemic PD149163, a neurotensin receptor 1 agonist, decreases methamphetamine self-administration in DBA/2J mice without causing excessive sedation. PloS one. vol 12. issue 7. 2017-10-06. PMID:28686721. |
meth activates the central dopaminergic "reward" circuitry, and with repeated use increases levels of the neuromodulatory peptide neurotensin in the nucleus accumbens and ventral tegmental area. |
2017-10-06 |
2023-08-13 |
mouse |
| Meaghan Creed, Niels R Ntamati, Ramesh Chandra, Mary Kay Lobo, Christian Lüsche. Convergence of Reinforcing and Anhedonic Cocaine Effects in the Ventral Pallidum. Neuron. vol 92. issue 1. 2017-10-03. PMID:27667004. |
cocaine-evoked synaptic plasticity in the reward system, particularly the nucleus accumbens (nac), drives drug-adaptive behavior. |
2017-10-03 |
2023-08-13 |
Not clear |
| Joanna Peris, Kaley MacFadyen, Justin A Smith, Annette D de Kloet, Lei Wang, Eric G Kraus. Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic targets. The Journal of comparative neurology. vol 525. issue 5. 2017-09-29. PMID:27615433. |
oxytocin (ot) has been implicated in mediating natural reward and ot-synthesizing neurons project to the ventral tegmental area (vta) and nucleus accumbens (nac); however, direct neuroanatomical evidence of ot regulation of da neurons within the vta is sparse. |
2017-09-29 |
2023-08-13 |
mouse |
| Sergueï O Fetisso. [Hunger and satiety factors in the regulation of pleasure associated with feeding behavior]. Biologie aujourd'hui. vol 210. issue 4. 2017-09-28. PMID:28327283. |
the dopamine (da) system of the mesolimbic projections plays a key role in behavioral reward in general and is also involved in regulating feeding-associated pleasure in the forebrain including the nucleus accumbens (nac) and the lateral hypothalamic area (lha). |
2017-09-28 |
2023-08-13 |
Not clear |
| Yuan-Hao Chen, Eagle Yi-Kung Huang, Tung-Tai Kuo, Barry J Hoffer, Jonathan Miller, Yu-Ching Chou, Yung-Hsiao Chian. Dopamine release in the nucleus accumbens is altered following traumatic brain injury. Neuroscience. vol 348. 2017-09-26. PMID:28196657. |
mild-to-severe traumatic brain injury (tbi) is frequently associated with prolonged dysfunction of reward circuitry, including motivation and salience, which suggests alterations of dopamine (da) processing within the core and shell of the nucleus accumbens (nac). |
2017-09-26 |
2023-08-13 |
Not clear |
| Gregory N Ruegsegger, Ryan G Toedebusch, Thomas E Childs, Kolter B Grigsby, Frank W Boot. Loss of Cdk5 function in the nucleus accumbens decreases wheel running and may mediate age-related declines in voluntary physical activity. The Journal of physiology. vol 595. issue 1. 2017-09-25. PMID:27461471. |
the nucleus accumbens (the pleasure and reward 'hub' in the brain) influences wheel running behaviour in rodents. |
2017-09-25 |
2023-08-13 |
Not clear |
| Ryan W Eaton, Tyler Libey, Eberhard E Fet. Operant conditioning of neural activity in freely behaving monkeys with intracranial reinforcement. Journal of neurophysiology. vol 117. issue 3. 2017-09-13. PMID:28031396. |
to reward cell activity in unconstrained primates, we sought sites in nucleus accumbens (nac) whose stimulation reinforced operant responding. |
2017-09-13 |
2023-08-13 |
monkey |
| Candace R Lewis, Ryan M Bastle, Tawny B Manning, Sarah M Himes, Paulette Fennig, Phoebe R Conrad, Jenna Colwell, Broc A Pagni, Lyndsay A Hess, Caitlin G Matekel, Jason M Newbern, M Foster Oliv. Interactions between Early Life Stress, Nucleus Accumbens MeCP2 Expression, and Methamphetamine Self-Administration in Male Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27312406. |
in addition, we show new evidence that both els and methamphetamine sa alter the expression of the epigenetic regulator methyl cpg-binding protein 2 (mecp2) in key brain reward regions, particularly in the nucleus accumbens (nac) core. |
2017-09-11 |
2023-08-13 |
rat |
| Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
the bilateral nucleus accumbens (nac) were selected as seeds to construct reward circuits across all subjects. |
2017-09-11 |
2023-08-13 |
human |
| Zachary V Johnson, Hasse Walum, Yao Xiao, Paula C Riefkohl, Larry J Youn. Oxytocin receptors modulate a social salience neural network in male prairie voles. Hormones and behavior. vol 87. 2017-09-07. PMID:27793769. |
in voles, otr density in the nucleus accumbens (nac)-a region important for social and reward learning-is associated with individual and species variation in social attachment behavior. |
2017-09-07 |
2023-08-13 |
Not clear |
| Maria A Mikhailova, Caroline E Bass, Valentina P Grinevich, Ann M Chappell, Alex L Deal, Keith D Bonin, Jeff L Weiner, Raul R Gainetdinov, Evgeny A Budygi. Optogenetically-induced tonic dopamine release from VTA-nucleus accumbens projections inhibits reward consummatory behaviors. Neuroscience. vol 333. 2017-09-06. PMID:27421228. |
we used optical activation of this dopamine circuit to mimic tonic dopamine release in the nucleus accumbens and to explore the causal relationship between this form of dopamine signaling within the ventral tegmental area (vta)-nucleus accumbens projection and consumption of a natural reward. |
2017-09-06 |
2023-08-13 |
rat |
| Christina K Kim, Li Ye, Joshua H Jennings, Nandini Pichamoorthy, Daniel D Tang, Ai-Chi W Yoo, Charu Ramakrishnan, Karl Deisserot. Molecular and Circuit-Dynamical Identification of Top-Down Neural Mechanisms for Restraint of Reward Seeking. Cell. vol 170. issue 5. 2017-09-01. PMID:28823561. |
here, we show that a specific subset of superficial mpfc projections to a subfield of nucleus accumbens (nac) neurons naturally encodes the decision to initiate or suppress reward seeking when faced with risk of punishment. |
2017-09-01 |
2023-08-13 |
Not clear |
| Andrea L Gutman, Sharif A Tah. Acute ethanol effects on neural encoding of reward size and delay in the nucleus accumbens. Journal of neurophysiology. vol 116. issue 3. 2017-08-28. PMID:27169507. |
acute ethanol effects on neural encoding of reward size and delay in the nucleus accumbens. |
2017-08-28 |
2023-08-13 |
rat |
| Shuntaro Kohnomi, Katsuko Ebihara, Masayuki Kobayash. Suppressive regulation of lateral inhibition between medium spiny neurons via dopamine D Neuroscience letters. vol 636. 2017-08-24. PMID:27793700. |
suppressive regulation of lateral inhibition between medium spiny neurons via dopamine d the nucleus accumbens (nac) shell is closely associated with reward, psychiatric disorders (depression or schizophrenia), and drug abuse. |
2017-08-24 |
2023-08-13 |
Not clear |
| E Kalon, J Y Hong, C Tobin, T Schult. Psychological and Neurobiological Correlates of Food Addiction. International review of neurobiology. vol 129. 2017-08-23. PMID:27503449. |
although preliminary, neuroimaging studies in response to food cues and the consumption of highly palatable food in individuals with fa compared to healthy controls have shown differing activation patterns and connectivity in brain reward circuits including regions such as the striatum, amygdala, orbitofrontal cortex, insula, and nucleus accumbens. |
2017-08-23 |
2023-08-13 |
Not clear |
| T Chase Francis, Mary Kay Lob. Emerging Role for Nucleus Accumbens Medium Spiny Neuron Subtypes in Depression. Biological psychiatry. vol 81. issue 8. 2017-08-22. PMID:27871668. |
the ventral striatum (nucleus accumbens) and its role in mood, reward, and motivation has been the focus of significant research. |
2017-08-22 |
2023-08-13 |
Not clear |
| Qiwen Hu, Eun Ji Kim, Jian Feng, Gregory R Grant, Elizabeth A Helle. Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain. PLoS computational biology. vol 13. issue 6. 2017-08-18. PMID:28609483. |
to address this, we have developed novel computational approaches to model the association between alternative splicing and histone posttranslational modifications in the nucleus accumbens (nac), a brain reward region. |
2017-08-18 |
2023-08-13 |
mouse |
| Fabricio H Do-Monte, Angélica Minier-Toribio, Kelvin Quiñones-Laracuente, Estefanía M Medina-Colón, Gregory J Quir. Thalamic Regulation of Sucrose Seeking during Unexpected Reward Omission. Neuron. vol 94. issue 2. 2017-08-08. PMID:28426970. |
photoinhibition of apvt projections to the nucleus accumbens or to the amygdala increased or decreased, respectively, sucrose seeking only when reward was omitted. |
2017-08-08 |
2023-08-13 |
Not clear |
| Michael Loureiro, Cecilia Kramar, Justine Renard, Laura G Rosen, Steven R Laviolett. Cannabinoid Transmission in the Hippocampus Activates Nucleus Accumbens Neurons and Modulates Reward and Aversion-Related Emotional Salience. Biological psychiatry. vol 80. issue 3. 2017-08-07. PMID:26681496. |
cannabinoid transmission in the hippocampus activates nucleus accumbens neurons and modulates reward and aversion-related emotional salience. |
2017-08-07 |
2023-08-13 |
Not clear |
| Paula A Gajewski, Gustavo Turecki, Alfred J Robiso. Differential Expression of FosB Proteins and Potential Target Genes in Select Brain Regions of Addiction and Depression Patients. PloS one. vol 11. issue 8. 2017-07-31. PMID:27494187. |
the transcription factor Δfosb is induced in the prefrontal cortex (pfc) and hippocampus (hpc) of rodents in response to stress or cocaine, and its expression in these regions is thought to regulate their "top down" control of reward circuitry, including the nucleus accumbens (nac). |
2017-07-31 |
2023-08-13 |
human |