All Relations between reward and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
R M Pasco Fearo. Editorial: Looking beyond the horizon--innovation in child psychology and psychiatry. Journal of child psychology and psychiatry, and allied disciplines. vol 57. issue 3. 2016-12-15. PMID:26889890. (1) i like to think that in doing so we have been quietly undertaking a giant pavlovian conditioning experiment: every year, as the spring flowers start to blossom (in the northern hemisphere at least), the nucleus accumbens of child psychologists and psychiatrists around the world begin to glow in anticipation of intellectual reward. 2016-12-15 2023-08-13 Not clear
In-Jee You, Sherie R Wright, Alvaro L Garcia-Garcia, Andrew R Tapper, Paul D Gardner, George F Koob, E David Leonardo, Laura M Bohn, Sunmee We. 5-HT1A Autoreceptors in the Dorsal Raphe Nucleus Convey Vulnerability to Compulsive Cocaine Seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 5. 2016-12-14. PMID:26324408. in addition, using designer receptors exclusively activated by designer drugs (dreadds) technology, we found that stimulation of the serotonergic dorsal raphe nucleus (drn) afferents to the nucleus accumbens (nac) abolishes cocaine reward and promotes antidepressive-like behaviors. 2016-12-14 2023-08-13 mouse
Petra Suchankova, Jörgen A Engel, Elisabet Jerlha. Sub-chronic Ghrelin Receptor Blockade Attenuates Alcohol- and Amphetamine-Induced Locomotor Stimulation in Mice. Alcohol and alcoholism (Oxford, Oxfordshire). vol 51. issue 2. 2016-12-13. PMID:26330568. the findings that ghrelin receptors (ghs-r1a) are expressed in reward-related areas, including the nucleus accumbens (nac) and ventral tegmental area (vta), suggest that ghrelin is a novel reward regulator. 2016-12-13 2023-08-13 mouse
Jessica R Gugusheff, Sung Eun Bae, Alexandra Rao, Iain J Clarke, Lucilla Poston, Paul D Taylor, Clive W Coen, Beverly S Muhlhausle. Sex and age-dependent effects of a maternal junk food diet on the mu-opioid receptor in rat offspring. Behavioural brain research. vol 301. 2016-10-20. PMID:26718219. this study aimed to determine the impact of a maternal junk food (jf) diet on mu-opioid receptor (mur) expression and ligand binding in two key regions of the reward pathway, the nucleus accumbens (nac) and the ventral tegmental area (vta) in rats during the early suckling (postnatal day (pnd) 1 and 7) and late suckling/early post-weaning (pnd 21 and 28) periods. 2016-10-20 2023-08-13 rat
Rhona B C Clarke, Bo Söderpalm, Amir Lotfi, Mia Ericson, Louise Adermar. Involvement of Inhibitory Receptors in Modulating Dopamine Signaling and Synaptic Activity Following Acute Ethanol Exposure in Striatal Subregions. Alcoholism, clinical and experimental research. vol 39. issue 12. 2016-10-06. PMID:26614538. alcohol acts on both inhibitory and excitatory receptor systems resulting in a net increase in dopamine output in the ventral striatum (nucleus accumbens [nac]), which is implicated in drug reward. 2016-10-06 2023-08-13 Not clear
Mitra Heshmati, Sam A Golden, Madeline L Pfau, Daniel J Christoffel, Elena L Seeley, Michael E Cahill, Lena A Khibnik, Scott J Russ. Mefloquine in the nucleus accumbens promotes social avoidance and anxiety-like behavior in mice. Neuropharmacology. vol 101. 2016-10-05. PMID:26471420. direct infusion of mefloquine into the nucleus accumbens (nac), a key brain reward region, increased stress-induced social avoidance and anxiety behavior. 2016-10-05 2023-08-13 mouse
Lauren N Beloate, Peyton W Weems, Graham R Casey, Ian C Webb, Lique M Coole. Nucleus accumbens NMDA receptor activation regulates amphetamine cross-sensitization and deltaFosB expression following sexual experience in male rats. Neuropharmacology. vol 101. 2016-09-22. PMID:26391065. moreover, sexual experience induces neural plasticity within the nucleus accumbens (nac), including induction of deltafosb, which plays a key role in amph reward cross-sensitization. 2016-09-22 2023-08-13 rat
Judith K Morgan, Daniel S Shaw, Thomas M Olino, Samuel C Musselman, Nikhil T Kurapati, Erika E Forbe. History of Depression and Frontostriatal Connectivity During Reward Processing in Late Adolescent Boys. Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. vol 45. issue 1. 2016-09-15. PMID:25915469. history of depression in late adolescent boys may be associated with altered coordination between the nucleus accumbens and mpfc when winning reward. 2016-09-15 2023-08-13 human
N A Elvemo, N I Landrø, P C Borchgrevink, A K Håber. Reward responsiveness in patients with chronic pain. European journal of pain (London, England). vol 19. issue 10. 2016-09-06. PMID:25766961. the second aim was to investigate the relationship between reward processing and nucleus accumbens volume in pcp and controls. 2016-09-06 2023-08-13 Not clear
N A Elvemo, N I Landrø, P C Borchgrevink, A K Håber. Reward responsiveness in patients with chronic pain. European journal of pain (London, England). vol 19. issue 10. 2016-09-06. PMID:25766961. nucleus accumbens is central in reward processing and its structure has been shown to be affected by chronic pain conditions in previous studies. 2016-09-06 2023-08-13 Not clear
Ahmad Salti, Kai K Kummer, Chinmaya Sadangi, Georg Dechant, Alois Saria, Rana El Rawa. Social interaction reward decreases p38 activation in the nucleus accumbens shell of rats. Neuropharmacology. vol 99. 2016-08-30. PMID:26300300. given the emerging role of p38 in stress/anxiety behaviors, these results suggest that (1) social interaction reward has anti-stress effects; (2) cocaine conditioning per se does not affect p38 activation and that (3) marginal stress is sufficient to induce p38 activation in the shell of the nucleus accumbens. 2016-08-30 2023-08-13 rat
Heiko Graf, Coraline D Metzger, Martin Walter, Birgit Able. Serotonergic antidepressants decrease hedonic signals but leave learning signals in the nucleus accumbens unaffected. Neuroreport. vol 27. issue 1. 2016-08-30. PMID:26555033. during functional mri, we used an established monetary incentive task to explore neural prediction error signals within the bilateral nucleus accumbens as region of interest within the dopaminergic reward system. 2016-08-30 2023-08-13 human
Jonathan Savitz, Robert Dantzer, Timothy B Meier, Brent E Wurfel, Teresa A Victor, Scott A McIntosh, Bart N Ford, Harvey M Morris, Jerzy Bodurka, T Kent Teague, Wayne C Drevet. Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder. Psychoneuroendocrinology. vol 62. 2016-08-24. PMID:26232650. given the central role of the nucleus accumbens (nacc) and other regions of the striatum in motivated behavior, reward processing, and anhedonia, we hypothesized that abnormalities in the concentrations of kynurenine pathway metabolites would be associated with striatal volumes. 2016-08-24 2023-08-13 Not clear
Luna Prieto-Garcia, Emil Egecioglu, Erik Studer, Lars Westberg, Elisabet Jerlha. Ghrelin and GHS-R1A signaling within the ventral and laterodorsal tegmental area regulate sexual behavior in sexually naïve male mice. Psychoneuroendocrinology. vol 62. 2016-08-18. PMID:26398679. the ability of ghrelin to regulate reinforcement involves the cholinergic-dopaminergic reward link, which encompasses a cholinergic projection from the laterodorsal tegmental area (ldtg) to the ventral tegmental area (vta) together with mesolimbic dopaminergic projections from the vta to the nucleus accumbens (nac). 2016-08-18 2023-08-13 mouse
HaoSheng Sun, Jennifer A Martin, Craig T Werner, Zi-Jun Wang, Diane M Damez-Werno, Kimberly N Scobie, Ning-Yi Shao, Caroline Dias, Jacqui Rabkin, Ja Wook Koo, Amy M Gancarz, Ezekiell A Mouzon, Rachael L Neve, Li Shen, David M Dietz, Eric J Nestle. BAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 14. 2016-08-15. PMID:27053203. here, we demonstrate that baz1b, an accessory subunit of the iswi family of chromatin remodeling complexes, is upregulated in the nucleus accumbens (nac), a key brain reward region, in both chronic cocaine-treated mice and mice that are resilient to chronic social defeat stress. 2016-08-15 2023-08-13 mouse
Elizabeth N Holly, Christopher O Boyson, Sandra Montagud-Romero, Dirson J Stein, Kyle L Gobrogge, Joseph F DeBold, Klaus A Micze. Episodic Social Stress-Escalated Cocaine Self-Administration: Role of Phasic and Tonic Corticotropin Releasing Factor in the Anterior and Posterior Ventral Tegmental Area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 14. 2016-08-15. PMID:27053215. reward and stress both activate ventral tegmental area (vta) dopamine neurons, increasing downstream extracellular dopamine concentration in the medial prefrontal cortex and nucleus accumbens. 2016-08-15 2023-08-13 rat
Veronica A Alvare. Clues on the coding of reward cues by the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 10. 2016-08-10. PMID:26917689. clues on the coding of reward cues by the nucleus accumbens. 2016-08-10 2023-08-13 Not clear
Elaine B Sinclair, Kristen M Culbert, Dana R Gradl, Kimberlei A Richardson, Kelly L Klump, Cheryl L Sis. Differential mesocorticolimbic responses to palatable food in binge eating prone and binge eating resistant female rats. Physiology & behavior. vol 152. issue Pt A. 2016-08-08. PMID:26459117. the mesocorticolimbic reward circuit, including the nucleus accumbens and the medial prefrontal cortex, is likely involved because this circuit mediates the hedonic value and incentive salience of palatable foods (pf). 2016-08-08 2023-08-13 rat
Masroor Shariff, Maryka Quik, Joan Holgate, Michael Morgan, Omkar L Patkar, Vincent Tam, Arnauld Belmer, Selena E Bartlet. Neuronal Nicotinic Acetylcholine Receptor Modulators Reduce Sugar Intake. PloS one. vol 11. issue 3. 2016-08-08. PMID:27028298. interestingly, increased sugar consumption has been shown to repeatedly elevate dopamine levels in the nucleus accumbens (nac), in the mesolimbic reward pathway of the brain similar to many drugs of abuse. 2016-08-08 2023-08-13 Not clear
D Y Sakae, F Marti, S Lecca, F Vorspan, E Martín-García, L J Morel, A Henrion, J Gutiérrez-Cuesta, A Besnard, N Heck, E Herzog, S Bolte, V F Prado, M A M Prado, F Bellivier, C B Eap, S Crettol, P Vanhoutte, J Caboche, A Gratton, L Moquin, B Giros, R Maldonado, S Daumas, M Mameli, S Jamain, S El Mestikaw. The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens. Molecular psychiatry. vol 20. issue 11. 2016-08-02. PMID:26239290. tonically active cholinergic interneurons (tans) from the nucleus accumbens (nac) are centrally involved in reward behavior. 2016-08-02 2023-08-13 mouse