| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianbo Zhang, Na Wang, Bo Chen, Yi'nan Wang, Jing He, Xintong Cai, Hongbo Zhang, Shuguang Wei, Shengbin L. Blockade of Cannabinoid CB1 receptor attenuates the acquisition of morphine-induced conditioned place preference along with a downregulation of ERK, CREB phosphorylation, and BDNF expression in the nucleus accumbens and hippocampus. Neuroscience letters. vol 630. 2017-07-26. PMID:27461790. |
in the present study, we investigated the relationship between cb1r and the extracellular signal-regulated kinase (erk), camp response element-binding protein (creb), brain-derived neurotrophic factor (bdnf) signaling in the nucleus accumbens (nac) and hippocampus in morphine-induced conditioned place preference (cpp), which is used to assess the morphine-induced reward memory. |
2017-07-26 |
2023-08-13 |
mouse |
| James M Kasper, David L McCue, Adrianna J Milton, Angelia Szwed, Catherine M Sampson, Mei Huang, Susan Carlton, Herbert Y Meltzer, Kathryn A Cunningham, Jonathan D Homme. Gamma-Aminobutyric Acidergic Projections From the Dorsal Raphe to the Nucleus Accumbens Are Regulated by Neuromedin U. Biological psychiatry. vol 80. issue 11. 2017-07-19. PMID:27105831. |
gamma-aminobutyric acidergic projections from the dorsal raphe to the nucleus accumbens are regulated by neuromedin u. neuromedin u (nmu) is a neuropeptide enriched in the nucleus accumbens shell (nacsh), a brain region associated with reward. |
2017-07-19 |
2023-08-13 |
Not clear |
| Daniel Vallöf, Jesper Vestlund, Jörgen A Engel, Elisabet Jerlha. The Anorexigenic Peptide Neuromedin U (NMU) Attenuates Amphetamine-Induced Locomotor Stimulation, Accumbal Dopamine Release and Expression of Conditioned Place Preference in Mice. PloS one. vol 11. issue 5. 2017-07-19. PMID:27139195. |
this reward link consists of a dopamine projection from the ventral tegmental area to the nucleus accumbens (nac) suggesting that these brain areas are important for reward. |
2017-07-19 |
2023-08-13 |
mouse |
| Gabriela Alarcón, Anita Cservenka, Bonnie J Nage. Adolescent neural response to reward is related to participant sex and task motivation. Brain and cognition. vol 111. 2017-07-19. PMID:27816780. |
motivation to earn money partially mediated the effect of sex on nucleus accumbens activity during reward. |
2017-07-19 |
2023-08-13 |
human |
| Hee-Dae Kim, Jennifer Hesterman, Tanessa Call, Samantha Magazu, Elizabeth Keeley, Kristyna Armenta, Hope Kronman, Rachael L Neve, Eric J Nestler, Deveroux Ferguso. SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 32. 2017-07-14. PMID:27511015. |
in the present study, we show that chronic social defeat stress, an ethologically validated model of depression in mice, increases sirt1 levels in the nucleus accumbens (nac), a key brain reward region. |
2017-07-14 |
2023-08-13 |
mouse |
| Kathryn Wallin-Miller, Grace Li, Diana Kelishani, Ruth I Woo. Anabolic-androgenic steroids decrease dendritic spine density in the nucleus accumbens of male rats. Neuroscience. vol 330. 2017-07-11. PMID:27238893. |
the mesocorticolimbic dopamine (da) system, particularly the nucleus accumbens (acb), is important for reward, motivated behavior, and higher cognitive processes such as decision making. |
2017-07-11 |
2023-08-13 |
rat |
| Jocelyn M Richard, Howard L Field. Mu-opioid receptor activation in the medial shell of nucleus accumbens promotes alcohol consumption, self-administration and cue-induced reinstatement. Neuropharmacology. vol 108. 2017-07-07. PMID:27089981. |
mu-opioid receptor activation in the medial shell of the nucleus accumbens (nac), a region implicated in multiple aspects of reward processing, elevates alcohol consumption while nac opioid antagonists reduce it. |
2017-07-07 |
2023-08-13 |
rat |
| Catarina Owesson-White, Anna M Belle, Natalie R Herr, Jessica L Peele, Preethi Gowrishankar, Regina M Carelli, R Mark Wightma. Cue-Evoked Dopamine Release Rapidly Modulates D2 Neurons in the Nucleus Accumbens During Motivated Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 22. 2017-07-06. PMID:27251622. |
dopaminergic neurons that project from the ventral tegmental area (vta) to the nucleus accumbens (nac) fire in response to unpredicted rewards or to cues that predict reward delivery. |
2017-07-06 |
2023-08-13 |
rat |
| Takahiro Kato, Soichiro Ide, Masabumi Minam. Pain relief induces dopamine release in the rat nucleus accumbens during the early but not late phase of neuropathic pain. Neuroscience letters. vol 629. 2017-06-29. PMID:27369326. |
the neuronal pathway from the ventral tegmental area to the nucleus accumbens (nac) is critical in the mesolimbic dopamine (da) reward circuit, and dysfunction of this pathway has been implicated in depression. |
2017-06-29 |
2023-08-13 |
rat |
| Saara Nuutinen, Tiia Mäki, Stanislav Rozov, Pia Bäckström, Petri Hyytiä, Petteri Piepponen, Pertti Panul. Histamine H3 receptor antagonist decreases cue-induced alcohol reinstatement in mice. Neuropharmacology. vol 106. 2017-06-27. PMID:26107118. |
alcohol alone does not affect histamine release in the nucleus accumbens but h3r antagonist instead increases histamine release significantly suggesting that the mechanism by which h3r antagonist inhibits alcohol seeking found in the present study and the decreased alcohol reinforcement, reward and consumption found earlier might include alterations in the histaminergic neurotransmission in the nucleus accumbens. |
2017-06-27 |
2023-08-13 |
mouse |
| Scott E Kanoski, Matthew R Hayes, Karolina P Skibick. GLP-1 and weight loss: unraveling the diverse neural circuitry. American journal of physiology. Regulatory, integrative and comparative physiology. vol 310. issue 10. 2017-06-27. PMID:27030669. |
particular attention is devoted to discussion regarding the numerous neural substrates through which glp-1 and glp-1 analogs act to reduce food intake and body weight, including various hypothalamic nuclei (arcuate nucleus of the hypothalamus, periventricular hypothalamus, lateral hypothalamic area), hindbrain nuclei (parabrachial nucleus, medial nucleus tractus solitarius), hippocampus (ventral subregion; vhp), and nuclei embedded within the mesolimbic reward circuitry [ventral tegmental area (vta) and nucleus accumbens (nac)]. |
2017-06-27 |
2023-08-13 |
Not clear |
| Giorgio Bergamini, Hannes Sigrist, Boris Ferger, Nicolas Singewald, Erich Seifritz, Christopher R Pryc. Depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: Relevance to motivation pathologies. Neuropharmacology. vol 109. 2017-06-19. PMID:27036890. |
depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: relevance to motivation pathologies. |
2017-06-19 |
2023-08-13 |
mouse |
| Akemi Tomod. Preliminary Evidence for Impaired Brain Activity of Neural Reward Processing in Children and Adolescents with Reactive Attachment Disorder. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 136. issue 5. 2017-04-06. PMID:27150924. |
significantly reduced activity in the caudate and nucleus accumbens was observed during a high monetary reward condition in the rad group compared to the typically developed group. |
2017-04-06 |
2023-08-13 |
human |
| Nesrin F Basaran, R Levent Buyukuysal, M Sertac Yilmaz, Sami Aydin, Sinan Cavun, William R Millingto. The effect of Gly-Gln [ß-endorphin30-31] on morphine-evoked serotonin and GABA efflux in the nucleus accumbens of conscious rats. Neuropeptides. vol 58. 2017-02-13. PMID:26861257. |
in an earlier study, we found that gly-gln inhibits morphine-induced dopamine efflux in the nucleus accumbens (nac), consistent with its ability to inhibit morphine reward. |
2017-02-13 |
2023-08-13 |
rat |
| A H Putman, A R Wolen, J L Harenza, R K Yordanova, B T Webb, E J Chesler, M F Mile. Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains. Genes, brain, and behavior. vol 15. issue 4. 2017-01-24. PMID:26948279. |
through integration of genome-wide mrna expression profiles of the mesocorticolimbic reward circuit (prefrontal cortex, nucleus accumbens and ventral midbrain) across the bxd ri panel, we identified high priority candidate genes within etanq1, the strongest of which was ninein (nin), a gsk3β-interacting protein that is highly expressed in the brain. |
2017-01-24 |
2023-08-13 |
mouse |
| Walter Swardfager, Joshua D Rosenblat, Meriem Benlamri, Roger S McIntyr. Mapping inflammation onto mood: Inflammatory mediators of anhedonia. Neuroscience and biobehavioral reviews. vol 64. 2016-12-27. PMID:26915929. |
as an exemplar, we consider the psychopathological domain of anhedonia, conceptualizing the relevance of inflammation (e.g., cellular immunity) and downstream processes (e.g., indoleamine 2,3-dioxygenase activation and oxidative inactivation of tetrahydrobiopterin) across rdoc units of analysis (e.g., catecholamine neurotransmitter molecules, nucleus accumbens medium spiny neuronal cells, dopaminergic mesolimbic and mesocortical reward circuits, animal paradigms, etc.). |
2016-12-27 |
2023-08-13 |
Not clear |
| R Renteria, Z M Jeanes, R A Mangieri, E Y Maier, D M Kircher, T R Buske, R A Morriset. Using In Vitro Electrophysiology to Screen Medications: Accumbal Plasticity as an Engram of Alcohol Dependence. International review of neurobiology. vol 126. 2016-12-27. PMID:27055622. |
the nucleus accumbens (nac) is a central component of the mesocorticolimbic reward system. |
2016-12-27 |
2023-08-13 |
Not clear |
| Takatoshi Hikida, Makiko Morita, Tom Macpherso. Neural mechanisms of the nucleus accumbens circuit in reward and aversive learning. Neuroscience research. vol 108. 2016-12-26. PMID:26827817. |
neural mechanisms of the nucleus accumbens circuit in reward and aversive learning. |
2016-12-26 |
2023-08-13 |
Not clear |
| Daniel A Abrams, Tianwen Chen, Paola Odriozola, Katherine M Cheng, Amanda E Baker, Aarthi Padmanabhan, Srikanth Ryali, John Kochalka, Carl Feinstein, Vinod Meno. Neural circuits underlying mother's voice perception predict social communication abilities in children. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 22. 2016-12-23. PMID:27185915. |
compared to female control voices, mother's voice elicited greater activity in primary auditory regions in the midbrain and cortex; voice-selective superior temporal sulcus (sts); the amygdala, which is crucial for processing of affect; nucleus accumbens and orbitofrontal cortex of the reward circuit; anterior insula and cingulate of the salience network; and a subregion of fusiform gyrus associated with face perception. |
2016-12-23 |
2023-08-13 |
human |
| Sarah J Baracz, Nicholas A Everett, Iain S McGregor, Jennifer L Cornis. Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine-seeking behaviour in rats. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25399704. |
recent findings demonstrated a reduction in meth-induced reward by oxytocin administration into the nucleus accumbens (nac) core. |
2016-12-20 |
2023-08-13 |
rat |