| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Wei, Y Wang, X Wang, Z He, M Zhang, X Zhang, Y Pan, J Zhang, Z Qin, K Zhan. The different effects of high-frequency stimulation of the nucleus accumbens shell and core on food consumption are possibly associated with different neural responses in the lateral hypothalamic area. Neuroscience. vol 301. 2016-04-18. PMID:26071960. |
obesity may result from dysfunction of the reward system, especially in the nucleus accumbens (acb). |
2016-04-18 |
2023-08-13 |
rat |
| Duo Xu, Chen Su, Hau-Yueh Lin, Toby Manders, Jing Wan. Persistent neuropathic pain increases synaptic GluA1 subunit levels in core and shell subregions of the nucleus accumbens. Neuroscience letters. vol 609. 2016-04-15. PMID:26477778. |
the nucleus accumbens (nac) is a key component of the brain reward system, and it is composed of core and shell subregions. |
2016-04-15 |
2023-08-13 |
Not clear |
| Hossein Khaleghzadeh-Ahangar, Abbas Haghparas. Intra-accumbal CB1 receptor blockade reduced extinction and reinstatement of morphine. Physiology & behavior. vol 149. 2016-04-11. PMID:26057574. |
the limbic dopaminergic reward system is the main target of morphine-like drugs which begins from the ventral tegmental area (vta) and sends its dopaminergic projections to the nucleus accumbens (nac), amygdala, hippocampus and prefrontal cortex. |
2016-04-11 |
2023-08-13 |
rat |
| Edward J Modestino, Partrick O'Toole, AnnaMarie Reinhofe. Experiential and Doctrinal Religious Knowledge Categorization in Parkinson's Disease: Behavioral and Brain Correlates. Frontiers in human neuroscience. vol 10. 2016-04-06. PMID:27047360. |
in fcmri in pd, we found resting state functional intrinsic connectivity of reward networks associated with classification of statements using seeds in bilateral nucleus accumbens in pd. |
2016-04-06 |
2023-08-13 |
Not clear |
| Anita Cservenka, Alicia J Gillespie, Paul G Michael, Bonnie J Nage. Family history density of alcoholism relates to left nucleus accumbens volume in adolescent girls. Journal of studies on alcohol and drugs. vol 76. issue 1. 2016-04-04. PMID:25486393. |
because common structural abnormalities are present in reward and affective brain regions in alcoholics and those with familial alcoholism, the current study examined the relationship between familial loading of auds and volumes of the amygdala and nucleus accumbens (nacc) in largely alcohol-naive adolescents, ages 12-16 years (n = 140). |
2016-04-04 |
2023-08-13 |
Not clear |
| Eric J Nestle. ∆FosB: a transcriptional regulator of stress and antidepressant responses. European journal of pharmacology. vol 753. 2016-03-14. PMID:25446562. |
such prolonged induction of Δfosb, within nucleus accumbens (nac), a key brain reward region, has been most studied in animal models of drug addiction, with considerable evidence indicating that Δfosb promotes reward and motivation and serves as a mechanism of drug sensitization and increased drug self-administration. |
2016-03-14 |
2023-08-13 |
mouse |
| Rhona Clarke, Louise Adermar. Dopaminergic Regulation of Striatal Interneurons in Reward and Addiction: Focus on Alcohol. Neural plasticity. vol 2015. 2016-03-08. PMID:26246915. |
the ventral striatum (nucleus accumbens (nac)) and its reciprocal connection with the ventral tegmental area (vta) represent a primary component of the reward system, but reward-guided learning also involves the dorsal striatum and dopaminergic inputs from the substantia nigra. |
2016-03-08 |
2023-08-13 |
Not clear |
| Michael D Reed, David G C Hildebrand, Gabrielle Santangelo, Anthony Moffa, Ashley S Pira, Lisa Rycyna, Mia Radic, Katherine Price, Jonathan Archbold, Kristi McConnell, Lauren Girard, Kristen Morin, Anna Tang, Marcelo Febo, James R Stella. Assessing contributions of nucleus accumbens shell subregions to reward-seeking behavior. Drug and alcohol dependence. vol 153. 2016-03-02. PMID:26048642. |
the nucleus accumbens (nac) plays a key role in brain reward processes including drug seeking and reinstatement. |
2016-03-02 |
2023-08-13 |
Not clear |
| Rahul Pandit, Esther M van der Zwaal, Mieneke C M Luijendijk, Maike A D Brans, Andrea J van Rozen, Ralph J A Oude Ophuis, Louk J M J Vanderschuren, Roger A H Adan, Susanne E la Fleu. Central melanocortins regulate the motivation for sucrose reward. PloS one. vol 10. issue 3. 2016-02-29. PMID:25811380. |
mc receptors are widely expressed in both hypothalamic and extra-hypothalamic brain regions, including nuclei involved in food reward and motivation, such as the nucleus accumbens (nac) and the ventral tegmental area. |
2016-02-29 |
2023-08-13 |
rat |
| Rosemary C Bagot, Eric M Parise, Catherine J Peña, Hong-Xing Zhang, Ian Maze, Dipesh Chaudhury, Brianna Persaud, Roger Cachope, Carlos A Bolaños-Guzmán, Joseph F Cheer, Joseph Cheer, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature communications. vol 6. 2016-02-29. PMID:25952660. |
enhanced glutamatergic transmission in the nucleus accumbens (nac), a region critical for reward and motivation, has been implicated in the pathophysiology of depression; however, the afferent source of this increased glutamate tone is not known. |
2016-02-29 |
2023-08-13 |
mouse |
| Hye Ran Park, Jae Meen Lee, Hyo Eun Moon, Dong Soo Lee, Bung-Nyun Kim, Jinhyun Kim, Dong Gyu Kim, Sun Ha Pae. A Short Review on the Current Understanding of Autism Spectrum Disorders. Experimental neurobiology. vol 25. issue 1. 2016-02-29. PMID:26924928. |
besides the amygdala, the nucleus accumbens is also considered as the key structure which is related with the social reward response in asd. |
2016-02-29 |
2023-08-13 |
human |
| Yingjie Zhu, Carl F R Wienecke, Gregory Nachtrab, Xiaoke Che. A thalamic input to the nucleus accumbens mediates opiate dependence. Nature. vol 530. issue 7589. 2016-02-24. PMID:26840481. |
while multiple inputs to the nucleus accumbens regulate reward, little is known about the nucleus accumbens circuitry underlying withdrawal. |
2016-02-24 |
2023-08-13 |
mouse |
| Joshua Manning, Gretchen Reynolds, Zeynep M Saygin, Stefan G Hofmann, Mark Pollack, John D E Gabrieli, Susan Whitfield-Gabriel. Altered resting-state functional connectivity of the frontal-striatal reward system in social anxiety disorder. PloS one. vol 10. issue 4. 2016-02-04. PMID:25928647. |
functional connectivity of the reward system was analyzed by calculating whole-brain temporal correlations with a bilateral nucleus accumbens seed and a ventromedial prefrontal cortex seed. |
2016-02-04 |
2023-08-13 |
human |
| Joshua Manning, Gretchen Reynolds, Zeynep M Saygin, Stefan G Hofmann, Mark Pollack, John D E Gabrieli, Susan Whitfield-Gabriel. Altered resting-state functional connectivity of the frontal-striatal reward system in social anxiety disorder. PloS one. vol 10. issue 4. 2016-02-04. PMID:25928647. |
patients with social anxiety disorder, relative to the control group, had (1) decreased functional connectivity between the nucleus accumbens seed and other regions associated with reward, including ventromedial prefrontal cortex; (2) decreased functional connectivity between the ventromedial prefrontal cortex seed and lateral prefrontal regions, including the anterior and dorsolateral prefrontal cortices; and (3) increased functional connectivity between both the nucleus accumbens seed and the ventromedial prefrontal cortex seed with more posterior brain regions, including anterior cingulate cortex. |
2016-02-04 |
2023-08-13 |
human |
| Yoko H Ohnishi, Yoshinori N Ohnishi, Takanori Nakamura, Mizuki Ohno, Pamela J Kennedy, Yasuyuki Ohkawa, Ohkawa Yasuyuki, Akinori Nishi, Rachael Neve, Teruhisa Tsuzuki, Eric J Nestle. PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. PloS one. vol 10. issue 5. 2016-02-02. PMID:25962134. |
Δfosb is a stable transcription factor which accumulates in the nucleus accumbens (nac), a key part of the brain's reward circuitry, in response to chronic exposure to cocaine or other drugs of abuse. |
2016-02-02 |
2023-08-13 |
Not clear |
| Scott M Thompson, Angy J Kallarackal, Mark D Kvarta, Adam M Van Dyke, Tara A LeGates, Xiang Ca. An excitatory synapse hypothesis of depression. Trends in neurosciences. vol 38. issue 5. 2016-01-19. PMID:25887240. |
here, we propose an excitatory synapse hypothesis of depression in which chronic stress and genetic susceptibility cause changes in the strength of subsets of glutamatergic synapses at multiple locations, including the prefrontal cortex (pfc), hippocampus, and nucleus accumbens (nac), leading to a dysfunction of corticomesolimbic reward circuitry that underlies many of the symptoms of depression. |
2016-01-19 |
2023-08-13 |
Not clear |
| Ioannis N Mavridi. Music and the nucleus accumbens. Surgical and radiologic anatomy : SRA. vol 37. issue 2. 2016-01-15. PMID:25102783. |
the nucleus accumbens (na), the most important pleasure center of the human brain (dominates the reward system), is the 'king of neurosciences' and dopamine (da) can be rightfully considered as its 'crown' due to the fundamental role that this neurotransmitter plays in the brain's reward system. |
2016-01-15 |
2023-08-13 |
human |
| Gabriela Rodríguez-Manz. Glutamatergic transmission is involved in the long lasting sexual inhibition of sexually exhausted male rats. Pharmacology, biochemistry, and behavior. vol 131. 2016-01-15. PMID:25668128. |
copulation is a natural reward activating the mesocorticolimbic circuit and inducing nucleus accumbens dopamine release. |
2016-01-15 |
2023-08-13 |
rat |
| Sylvia A Morelli, Matthew D Sacchet, Jamil Zak. Common and distinct neural correlates of personal and vicarious reward: A quantitative meta-analysis. NeuroImage. vol 112. 2016-01-11. PMID:25554428. |
contrast analyses identified preferential engagement of the nucleus accumbens in response to personal as compared to vicarious reward, and in mentalizing-related structures in response to vicarious as compared to personal reward. |
2016-01-11 |
2023-08-13 |
Not clear |
| Vasiliki Mitsi, Dimitra Terzi, Immanuel Purushothaman, Lefteris Manouras, Sevasti Gaspari, Rachael L Neve, Maria Stratinaki, Jian Feng, Li Shen, Venetia Zachario. RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 36. 2016-01-04. PMID:26305935. |
here, we use the murine spared-nerve injury model of neuropathic pain to investigate the mechanism by which rgs9-2 in the nucleus accumbens (nac), a brain region involved in mood, reward, and motivation, modulates the actions of tricyclic antidepressants (tcas). |
2016-01-04 |
2023-08-13 |
Not clear |