All Relations between reward and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Rebecca Gregory, Hu Cheng, Heather A Rupp, Dale R Sengelaub, Julia R Heima. Oxytocin increases VTA activation to infant and sexual stimuli in nulliparous and postpartum women. Hormones and behavior. vol 69. 2015-08-24. PMID:25562711. because they have been shown to be associated with reward, the ventral tegmental area (vta) and nucleus accumbens (nac) were targeted as areas of expected alterations in activity. 2015-08-24 2023-08-13 human
Hikida . [JSNP Excellent Presentation Award for CINP2014: pathway-specific modulation of nucleus accumbens in reward and aversive learning behaviors and drug addiction via selective transmitter receptors]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 35. issue 2. 2015-08-21. PMID:26027067. [jsnp excellent presentation award for cinp2014: pathway-specific modulation of nucleus accumbens in reward and aversive learning behaviors and drug addiction via selective transmitter receptors]. 2015-08-21 2023-08-13 Not clear
Rozita H Anderberg, Christine Anefors, Filip Bergquist, Hans Nissbrandt, Karolina P Skibick. Dopamine signaling in the amygdala, increased by food ingestion and GLP-1, regulates feeding behavior. Physiology & behavior. vol 136. 2015-08-19. PMID:24560840. the literature focuses primarily on the nucleus accumbens as the key dopaminergic target in which enhanced dopamine signaling is associated with reward. 2015-08-19 2023-08-12 rat
Xincai Ji, Sucharita Saha, Gilles E Marti. The origin of glutamatergic synaptic inputs controls synaptic plasticity and its modulation by alcohol in mice nucleus accumbens. Frontiers in synaptic neuroscience. vol 7. 2015-08-10. PMID:26257641. it is widely accepted that long-lasting changes of synaptic strength in the nucleus accumbens (nac), a brain region involved in drug reward, mediate acute and chronic effects of alcohol. 2015-08-10 2023-08-13 mouse
Youngsun T Cho, Stephen Fromm, Amanda E Guyer, Allison Detloff, Daniel S Pine, Julie L Fudge, Monique Erns. Nucleus accumbens, thalamus and insula connectivity during incentive anticipation in typical adults and adolescents. NeuroImage. vol 66. 2015-08-06. PMID:23069809. studies of incentive processing have repeatedly demonstrated activation of nucleus accumbens (nac), thalamus, and anterior insula, three key components of reward neurocircuitry. 2015-08-06 2023-08-12 Not clear
Katja N Spreckelmeyer, Lena Rademacher, Frieder M Paulus, Gerhard Gründe. Neural activation during anticipation of opposite-sex and same-sex faces in heterosexual men and women. NeuroImage. vol 66. 2015-08-06. PMID:23128082. a significant interaction of sex-of-face and sex-of-participant was observed in a priori defined regions of interest in the brain reward system (including ventral tegmental area, nucleus accumbens and ventromedial prefrontal cortex), reflecting enhanced activation to cues signaling opposite-sex faces relative to same-sex faces in both, men and women. 2015-08-06 2023-08-12 human
Takuya Funayama, Yumiko Ikeda, Amane Tateno, Hidehiko Takahashi, Yoshiro Okubo, Haruhisa Fukayama, Hidenori Suzuk. Modafinil augments brain activation associated with reward anticipation in the nucleus accumbens. Psychopharmacology. vol 231. issue 16. 2015-08-04. PMID:24682502. the nucleus accumbens (nac) works as a key brain structure of the reward system, in which reward-related neural activity is well correlated with dopamine release from mesolimbic dopaminergic neurons. 2015-08-04 2023-08-12 Not clear
Hyung Shin Yoon, Naoki Adachi, Hiroshi Kunug. Microinjection of cocaine- and amphetamine-regulated transcript 55-102 peptide into the nucleus accumbens could modulate anxiety-related behavior in rats. Neuropeptides. vol 48. issue 6. 2015-08-03. PMID:25256086. cocaine- and amphetamine-regulated transcript (cart) peptide is abundantly expressed in the nucleus accumbens (nacc) and is involved in stress, anxiety and reward responses. 2015-08-03 2023-08-13 rat
Barbara R Braams, Anna C K van Duijvenvoorde, Jiska S Peper, Eveline A Cron. Longitudinal changes in adolescent risk-taking: a comprehensive study of neural responses to rewards, pubertal development, and risk-taking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 18. 2015-07-24. PMID:25948271. the aim of the current study was twofold: (1) to test patterns of age-related change (i.e., linear, quadratic, and cubic) in activity in the nucleus accumbens, a key reward region in the brain, in relation to change in puberty (self-report and testosterone levels), laboratory risk-taking and self-reported risk-taking tendency; and (2) to test whether individual differences in pubertal development and risk-taking behavior were contributors to longitudinal change in nucleus accumbens activity. 2015-07-24 2023-08-13 human
Edita Navratilova, Jennifer Yanhua Xie, Diana Meske, Chaoling Qu, Kozo Morimura, Alec Okun, Naohisa Arakawa, Michael Ossipov, Howard L Fields, Frank Porrec. Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 18. 2015-07-24. PMID:25948274. pain is aversive, and its relief elicits reward mediated by dopaminergic signaling in the nucleus accumbens (nac), a part of the mesolimbic reward motivation pathway. 2015-07-24 2023-08-13 rat
Haiyin Wu, Brian O'Neill, Dawn D Han, Keerthi Thirtamara-Rajamani, Yanlin Wang, Howard H G. Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter. Neuropharmacology. vol 86. 2015-07-14. PMID:24835281. in an earlier study we showed that aav-datwt injections in regions covering the lateral nucleus accumbens (nac) and lateral caudate-putamen (cpu) restored cocaine stimulation but not cocaine reward. 2015-07-14 2023-08-13 mouse
Mary M Heitzeg, Sandra Villafuerte, Barbara J Weiland, Mary-Anne Enoch, Margit Burmeister, Jon-Kar Zubieta, Robert A Zucke. Effect of GABRA2 genotype on development of incentive-motivation circuitry in a sample enriched for alcoholism risk. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 13. 2015-07-07. PMID:24975023. we investigated the impact of gabra2 on the developmental trajectory of nucleus accumbens (nacc) activation during anticipation of monetary reward from childhood to young adulthood. 2015-07-07 2023-08-13 human
Daniel C Castro, Shannon L Cole, Kent C Berridg. Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry. Frontiers in systems neuroscience. vol 9. 2015-06-30. PMID:26124708. the study of the neural bases of eating behavior, hunger, and reward has consistently implicated the lateral hypothalamus (lh) and its interactions with mesocorticolimbic circuitry, such as mesolimbic dopamine projections to nucleus accumbens (nac) and ventral pallidum (vp), in controlling motivation to eat. 2015-06-30 2023-08-13 Not clear
Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter, A Vania Apkaria. Risky monetary behavior in chronic back pain is associated with altered modular connectivity of the nucleus accumbens. BMC research notes. vol 7. 2015-06-25. PMID:25331931. the nucleus accumbens (nac) has a well established role in reward processing. 2015-06-25 2023-08-13 human
Michelle Lee, Toby R Manders, Sarah E Eberle, Chen Su, James D'amour, Runtao Yang, Hau Yueh Lin, Karl Deisseroth, Robert C Froemke, Jing Wan. Activation of corticostriatal circuitry relieves chronic neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 13. 2015-06-19. PMID:25834050. a key output target for the pfc is the nucleus accumbens (nac), an important component of the reward circuitry. 2015-06-19 2023-08-13 human
Jian Feng, Ningyi Shao, Keith E Szulwach, Vincent Vialou, Jimmy Huynh, Chun Zhong, Thuc Le, Deveroux Ferguson, Michael E Cahill, Yujing Li, Ja Wook Koo, Efrain Ribeiro, Benoit Labonte, Benjamin M Laitman, David Estey, Victoria Stockman, Pamela Kennedy, Thomas Couroussé, Isaac Mensah, Gustavo Turecki, Kym F Faull, Guo-li Ming, Hongjun Song, Guoping Fan, Patrizia Casaccia, Li Shen, Peng Jin, Eric J Nestle. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature neuroscience. vol 18. issue 4. 2015-06-08. PMID:25774451. we found that ten-eleven translocation protein 1 (tet1) was downregulated in mouse nucleus accumbens (nac), a key brain reward structure, by repeated cocaine administration, which enhanced behavioral responses to cocaine. 2015-06-08 2023-08-13 mouse
N D Volkow, D Tomasi, G-J Wang, J Logan, D L Alexoff, M Jayne, J S Fowler, C Wong, P Yin, C D. Stimulant-induced dopamine increases are markedly blunted in active cocaine abusers. Molecular psychiatry. vol 19. issue 9. 2015-06-05. PMID:24912491. dopamine signaling in nucleus accumbens is essential for cocaine reward. 2015-06-05 2023-08-13 human
Yu-Feng Huang, Chun Siong Soon, O'Dhaniel A Mullette-Gillman, Po-Jang Hsie. Pre-existing brain states predict risky choices. NeuroImage. vol 101. 2015-05-27. PMID:25067816. our results indicate that activities in the left nucleus accumbens and medial frontal gyrus can bias subsequent risky decision making, showing that neuronal activities in regions associated with uncertainty and reward processing are involved in biasing subsequent choice selection. 2015-05-27 2023-08-13 human
Praneeth Namburi, Anna Beyeler, Suzuko Yorozu, Gwendolyn G Calhoon, Sarah A Halbert, Romy Wichmann, Stephanie S Holden, Kim L Mertens, Melodi Anahtar, Ada C Felix-Ortiz, Ian R Wickersham, Jesse M Gray, Kay M Ty. A circuit mechanism for differentiating positive and negative associations. Nature. vol 520. issue 7549. 2015-05-27. PMID:25925480. here we show that bla neurons projecting to the nucleus accumbens (nac projectors) or the centromedial amygdala (cem projectors) undergo opposing synaptic changes following fear or reward conditioning. 2015-05-27 2023-08-13 Not clear
Jun-Jun Wang, Wen-Qing Yao, Yue-Jun Chen, Lan Ma, Ye-Zheng Ta. [Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332000. the results showed that: neuronal c-fos, zif268 protein expression levels in nucleus accumbens (nac) core both were elevated in cocaine retrieval group compared with those in saline retrieval (control) group during cocaine context-associated reward memory retrieval. 2015-05-16 2023-08-13 mouse