| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Coveleskie, A Gupta, L A Kilpatrick, E D Mayer, C Ashe-McNalley, J Stains, J S Labus, E A Maye. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. vol 5. 2015-01-20. PMID:25599560. |
neuroimaging studies in obese subjects have identified abnormal activation of key regions of central reward circuits, including the nucleus accumbens (nacc), in response to food-related stimuli. |
2015-01-20 |
2023-08-13 |
human |
| Lena Rademacher, Aallaa Salama, Gerhard Gründer, Katja N Spreckelmeye. Differential patterns of nucleus accumbens activation during anticipation of monetary and social reward in young and older adults. Social cognitive and affective neuroscience. vol 9. issue 6. 2015-01-16. PMID:23547243. |
differential patterns of nucleus accumbens activation during anticipation of monetary and social reward in young and older adults. |
2015-01-16 |
2023-08-12 |
human |
| Lena Rademacher, Aallaa Salama, Gerhard Gründer, Katja N Spreckelmeye. Differential patterns of nucleus accumbens activation during anticipation of monetary and social reward in young and older adults. Social cognitive and affective neuroscience. vol 9. issue 6. 2015-01-16. PMID:23547243. |
anticipation of either reward type recruited brain structures associated with reward, including the nucleus accumbens (nacc). |
2015-01-16 |
2023-08-12 |
human |
| Marloes S Oudijn, Jitschak G Storosum, Elise Nelis, Damiaan Deny. Is deep brain stimulation a treatment option for anorexia nervosa? BMC psychiatry. vol 13. 2015-01-06. PMID:24175936. |
given the overlap in symptomatology and neurocircuitry between reward-related disorders such as obsessive compulsive disorder (ocd) and an, and the established efficacy of accumbal dbs in ocd, we hypothesize that dbs of the nucleus accumbens (nac) and other areas associated with reward, e.g. |
2015-01-06 |
2023-08-12 |
Not clear |
| Jennifer S Mascaro, Patrick D Hackett, James K Rillin. Differential neural responses to child and sexual stimuli in human fathers and non-fathers and their hormonal correlates. Psychoneuroendocrinology. vol 46. 2015-01-06. PMID:24882167. |
on the other hand, non-fathers had significantly stronger neural responses to sexually provocative images in regions important for reward and approach-related motivation (dorsal caudate and nucleus accumbens). |
2015-01-06 |
2023-08-13 |
human |
| Hannah M Cates, Mackenzie Thibault, Madeline Pfau, Elizabeth Heller, Andrew Eagle, Paula Gajewski, Rosemary Bagot, Christopher Colangelo, Thomas Abbott, Gabby Rudenko, Rachael Neve, Eric J Nestler, Alfred J Robiso. Threonine 149 phosphorylation enhances ΔFosB transcriptional activity to control psychomotor responses to cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 34. 2014-12-22. PMID:25143625. |
of particular interest is the transcription factor Δfosb, a truncated and stable fosb gene product whose expression in nucleus accumbens (nac), a key reward region, is induced by chronic exposure to virtually all drugs of abuse and regulates their psychomotor and rewarding effects. |
2014-12-22 |
2023-08-13 |
mouse |
| Lena H Ernst, Michael M Plichta, Thomas Dresler, Anna K Zesewitz, Sara V Tupak, Florian B Haeussinger, Matthias Fischer, Thomas Polak, Andreas J Fallgatter, Ann-Christine Ehli. Prefrontal correlates of approach preferences for alcohol stimuli in alcohol dependence. Addiction biology. vol 19. issue 3. 2014-12-16. PMID:23145772. |
neurobiological models suggest hypersensitivity in the reward system [inter alia nucleus accumbens and orbitofrontal cortex (ofc)] to cause pathologically enhanced approach impulses towards alcohol stimuli. |
2014-12-16 |
2023-08-12 |
Not clear |
| Elena Vashchinkina, Anne Panhelainen, Teemu Aitta-Aho, Esa R Korp. GABAA receptor drugs and neuronal plasticity in reward and aversion: focus on the ventral tegmental area. Frontiers in pharmacology. vol 5. 2014-12-16. PMID:25505414. |
the vta dopamine neurons project to forebrain centers such as the nucleus accumbens and medial prefrontal cortex, and receive afferent projections from these brain regions and especially from the extended amygdala and lateral habenula, forming the major part of the reward and aversion circuitry. |
2014-12-16 |
2023-08-13 |
Not clear |
| Jonathan A Sugam, Michael P Saddoris, Regina M Carell. Nucleus accumbens neurons track behavioral preferences and reward outcomes during risky decision making. Biological psychiatry. vol 75. issue 10. 2014-12-03. PMID:24143880. |
nucleus accumbens neurons track behavioral preferences and reward outcomes during risky decision making. |
2014-12-03 |
2023-08-12 |
Not clear |
| Eric M Miller, Maya U Shankar, Brian Knutson, Samuel M McClur. Dissociating motivation from reward in human striatal activity. Journal of cognitive neuroscience. vol 26. issue 5. 2014-12-03. PMID:24345173. |
specifically, responses in the caudate and putamen increased with motivation, whereas nucleus accumbens activity increased with expected reward. |
2014-12-03 |
2023-08-12 |
human |
| Alessia Salamone, Stefania Zappettini, Massimo Grilli, Guendalina Olivero, Paula Agostinho, Angelo R Tomé, Jiayang Chen, Anna Pittaluga, Rodrigo A Cunha, Mario March. Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens. Neuropharmacology. vol 79. 2014-12-03. PMID:24373903. |
the presynaptic control of dopamine release in the nucleus accumbens (nac) by glutamate and acetylcholine has a profound impact on reward signaling. |
2014-12-03 |
2023-08-12 |
rat |
| Zhenyu Cai, Dalei Zhang, Ying Ying, Min Yan, Jianhua Yang, Fangyun Xu, Kiwan Oh, Zhenzhen H. Inhibitory modulation of CART peptides in accumbal neuron through decreasing interaction of CaMKIIα with dopamine D3 receptors. Brain research. vol 1557. 2014-12-03. PMID:24560901. |
previous studies in rats have shown that microinjections of cocaine- and amphetamine-regulated transcript (cart) peptide into the nucleus accumbens (nac; the area of the brain that mediates drug reward and reinforcement) attenuate the locomotor effects of psychostimulants. |
2014-12-03 |
2023-08-12 |
rat |
| A J Robison, Vincent Vialou, Hao-Sheng Sun, Benoit Labonte, Sam A Golden, Caroline Dias, Gustavo Turecki, Carol Tamminga, Scott Russo, Michelle Mazei-Robison, Eric J Nestle. Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24240473. |
recent work in addiction models demonstrates that the transcription factor Δfosb and protein kinase calmodulin-dependent protein kinase ii (camkii) are co-regulated in nucleus accumbens (nac), a brain reward region implicated in both addiction and depression models including social defeat. |
2014-12-01 |
2023-08-12 |
mouse |
| Yoshihisa Watanabe, Kanji Yoshimoto, Harutsugu Tatebe, Masakazu Kita, Kazuko Nishikura, Minoru Kimura, Masaki Tanak. Enhancement of alcohol drinking in mice depends on alterations in RNA editing of serotonin 2C receptors. The international journal of neuropsychopharmacology. vol 17. issue 5. 2014-12-01. PMID:24345557. |
here we show that enhanced alcohol drinking behaviour in mice is associated with the degree of 5-ht(2c)r mrna editing in the nucleus accumbens and dorsal raphe nuceus, brain regions important for reward and addiction. |
2014-12-01 |
2023-08-12 |
mouse |
| Yayoi Shigemune, Takashi Tsukiura, Toshimune Kambara, Ryuta Kawashim. Remembering with gains and losses: effects of monetary reward and punishment on successful encoding activation of source memories. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 5. 2014-11-28. PMID:23314939. |
fmri data demonstrated that the ventral tegmental area and substantia nigra and nucleus accumbens activations reflected both the processes of reward and punishment, whereas insular activation increased as a linear function of punishment. |
2014-11-28 |
2023-08-12 |
human |
| Na Yan, Ning Chen, Honghua Zhu, Jianguo Zhang, Moira Sim, Yu Ma, Wei Wan. High-frequency stimulation of nucleus accumbens changes in dopaminergic reward circuit. PloS one. vol 8. issue 11. 2014-11-24. PMID:24244479. |
high-frequency stimulation of nucleus accumbens changes in dopaminergic reward circuit. |
2014-11-24 |
2023-08-12 |
rat |
| Julen Hernandez Lallement, Katarina Kuss, Peter Trautner, Bernd Weber, Armin Falk, Klaus Fliessbac. Effort increases sensitivity to reward and loss magnitude in the human brain. Social cognitive and affective neuroscience. vol 9. issue 3. 2014-11-18. PMID:23202663. |
results show that reward magnitude positively modulates activity in reward-processing brain areas (subgenual anterior cingulate cortex and nucleus accumbens) only in the high effort condition. |
2014-11-18 |
2023-08-12 |
human |
| Anita Cservenka, Kaitlyn Casimo, Damien A Fair, Bonnie J Nage. Resting state functional connectivity of the nucleus accumbens in youth with a family history of alcoholism. Psychiatry research. vol 221. issue 3. 2014-11-02. PMID:24440571. |
the nucleus accumbens (nacc), a key brain region for reward processing, is implicated in the development of auds. |
2014-11-02 |
2023-08-12 |
Not clear |
| Floor van Heesch, Jolanda Prins, Jan Pieter Konsman, Gerdien A H Korte-Bouws, Koen G C Westphal, Joanna Rybka, Berend Olivier, Aletta D Kraneveld, S Mechiel Kort. Lipopolysaccharide increases degradation of central monoamines: an in vivo microdialysis study in the nucleus accumbens and medial prefrontal cortex of mice. European journal of pharmacology. vol 725. 2014-10-28. PMID:24444442. |
the dose of lps, shown to decrease responding for brain stimulation reward in mice, significantly increased extracellular levels of monoamine metabolites (5-hiaa, dopac and hva) in the nucleus accumbens and medial prefrontal cortex. |
2014-10-28 |
2023-08-12 |
mouse |
| Emily A Young, Sarah E Dreumont, Christopher L Cunningha. Role of nucleus accumbens dopamine receptor subtypes in the learning and expression of alcohol-seeking behavior. Neurobiology of learning and memory. vol 108. 2014-10-14. PMID:23742917. |
in contrast, intra-acb antagonist infusion had no effect on ethanol cpp expression, suggesting that dopamine's role in the acb is limited to neurobiological processes engaged during the learning of the relationship between contextual cues and ethanol reward. |
2014-10-14 |
2023-08-12 |
mouse |