| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emily A Young, Sarah E Dreumont, Christopher L Cunningha. Role of nucleus accumbens dopamine receptor subtypes in the learning and expression of alcohol-seeking behavior. Neurobiology of learning and memory. vol 108. 2014-10-14. PMID:23742917. |
overall, these data suggest that d1-like (but not d2-like) dopamine acb receptors play an important role in the learning of context-ethanol associations, either by modulating the magnitude of ethanol reward or the rate of learning about ethanol reward. |
2014-10-14 |
2023-08-12 |
mouse |
| Nicola M Grissom, Randolph Lyde, Lori Christ, Isaac E Sasson, JesseLea Carlin, Alexa P Vitins, Rebecca A Simmons, Teresa M Reye. Obesity at conception programs the opioid system in the offspring brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 4. 2014-10-10. PMID:23924601. |
expression of the mu-opioid receptor (mor), preproenkephalin (penk), and the dopamine transporter was evaluated in the hypothalamus and reward circuitry (ventral tegmental area, prefrontal cortex, and nucleus accumbens) in adult and late embryonic brains. |
2014-10-10 |
2023-08-12 |
Not clear |
| Nobuhito Abe, Joshua D Green. Response to anticipated reward in the nucleus accumbens predicts behavior in an independent test of honesty. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 32. 2014-10-03. PMID:25100590. |
response to anticipated reward in the nucleus accumbens predicts behavior in an independent test of honesty. |
2014-10-03 |
2023-08-13 |
human |
| Nobuhito Abe, Joshua D Green. Response to anticipated reward in the nucleus accumbens predicts behavior in an independent test of honesty. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 32. 2014-10-03. PMID:25100590. |
human subjects undergoing fmri completed a monetary incentive delay task eliciting responses to anticipated reward in the nucleus accumbens. |
2014-10-03 |
2023-08-13 |
human |
| Nobuhito Abe, Joshua D Green. Response to anticipated reward in the nucleus accumbens predicts behavior in an independent test of honesty. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 32. 2014-10-03. PMID:25100590. |
individuals showing relatively strong nucleus accumbens responses to anticipated reward also exhibited increased dorsolateral prefrontal activity (bilateral) in response to opportunities for dishonest gain. |
2014-10-03 |
2023-08-13 |
human |
| Jeffrey M Spielberg, Thomas M Olino, Erika E Forbes, Ronald E Dah. Exciting fear in adolescence: does pubertal development alter threat processing? Developmental cognitive neuroscience. vol 8. 2014-09-29. PMID:24548554. |
pubertal increases in testosterone predicted increased activation to threat cues, not only in regions associated with threat avoidance (i.e., amygdala), but also regions associated with reward pursuit (i.e., nucleus accumbens). |
2014-09-29 |
2023-08-12 |
Not clear |
| Tobias Bracht, Helge Horn, Werner Strik, Andrea Federspiel, Susanne Schnell, Oliver Höfle, Katharina Stegmayer, Roland Wiest, Thomas Dierks, Thomas J Müller, Sebastian Walthe. White matter microstructure alterations of the medial forebrain bundle in melancholic depression. Journal of affective disorders. vol 155. 2014-09-17. PMID:24252169. |
the medial forebrain bundle (mfb) is a key structure of the reward system and connects the ventral tegmental area (vta) with the nucleus accumbens (nacc), the medial and lateral orbitofrontal cortex (mofc, lofc) and the dorsolateral prefrontal cortex (dlpfc). |
2014-09-17 |
2023-08-12 |
Not clear |
| Corinde E Wiers, Christine Stelzel, Soyoung Q Park, Christiane K Gawron, Vera U Ludwig, Stefan Gutwinski, Andreas Heinz, Johannes Lindenmeyer, Reinout W Wiers, Henrik Walter, Felix Bermpoh. Neural correlates of alcohol-approach bias in alcohol addiction: the spirit is willing but the flesh is weak for spirits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 3. 2014-09-10. PMID:24060832. |
in the approach, alcohol fmri contrast patients showed larger blood-oxygen-level-dependent responses in the nucleus accumbens and medial prefrontal cortex, regions involved in reward and motivational processing. |
2014-09-10 |
2023-08-12 |
human |
| Lisa A Briand, Blake A Kimmey, Pavel I Ortinski, Richard L Huganir, R Christopher Pierc. Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 3. 2014-09-10. PMID:24126453. |
the current study demonstrates that conditional deletion of grip within the nucleus accumbens potentiates cue-induced reinstatement of cocaine seeking without affecting operant learning, locomotor activity, or reinstatement of natural reward seeking. |
2014-09-10 |
2023-08-12 |
Not clear |
| Kyle K Pitchers, Caroline M Coppens, Lauren N Beloate, Jonathan Fuller, Sandy Van, Karla S Frohmader, Steven R Laviolette, Michael N Lehman, Lique M Coole. Endogenous opioid-induced neuroplasticity of dopaminergic neurons in the ventral tegmental area influences natural and opiate reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 26. 2014-08-21. PMID:24966382. |
natural reward and drugs of abuse converge on the mesolimbic pathway and activate common mechanism of neural plasticity in the nucleus accumbens. |
2014-08-21 |
2023-08-13 |
rat |
| Nicole Y L Oei, Stephanie Both, Diana van Heemst, Jeroen van der Gron. Acute stress-induced cortisol elevations mediate reward system activity during subconscious processing of sexual stimuli. Psychoneuroendocrinology. vol 39. 2014-07-31. PMID:24275010. |
stress is thought to alter motivational processes by increasing dopamine (da) secretion in the brain's "reward system", and its key region, the nucleus accumbens (nacc). |
2014-07-31 |
2023-08-12 |
human |
| Eugene A Kiyatkin, Albert H Kim, Ken T Wakabayashi, Michael H Baumann, Yavin Shaha. Critical role of peripheral vasoconstriction in fatal brain hyperthermia induced by MDMA (Ecstasy) under conditions that mimic human drug use. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 23. 2014-07-25. PMID:24899699. |
we chronically implanted thermocouple microsensors in the nucleus accumbens (a brain reward area), temporal muscle, and facial skin to measure temperature continuously from freely moving rats. |
2014-07-25 |
2023-08-13 |
human |
| Arlene Martínez-Rivera, Enrique Rodríguez-Borrero, María Matías-Alemán, Alexandra Montalvo-Acevedo, Kathleen Guerrero-Figuereo, Liz J Febo-Rodríguez, Amarilys Morales-Rivera, Carmen S Maldonado-Vlaa. Metabotropic glutamate receptor 5 within nucleus accumbens shell modulates environment-elicited cocaine conditioning expression. Pharmacology, biochemistry, and behavior. vol 110. 2014-07-15. PMID:23850523. |
the metabotropic glutamate receptors 5 (mglurs5) within the nucleus accumbens (nac) have been implicated in the modulation of psychostimulant reward. |
2014-07-15 |
2023-08-12 |
rat |
| R Pandit, S E la Fleur, R A H Ada. The role of melanocortins and Neuropeptide Y in food reward. European journal of pharmacology. vol 719. issue 1-3. 2014-07-02. PMID:23872406. |
research suggests that npy/melanocortin regulate hedonic aspects of feeding through its projections to the brain reward circuitry (ventral tegmental area, lateral hypothalamus, nucleus accumbens etc. |
2014-07-02 |
2023-08-12 |
Not clear |
| Zahra Taslimi, Reza Arezoomandan, Alireza Omranifard, Mohadeseh Ghalandari-Shamami, Esmail Riahi, Abbas Ali Vafaei, Ali Rashidy-Pour, Abbas Haghparas. Orexin A in the ventral tegmental area induces conditioned place preference in a dose-dependent manner: involvement of D1/D2 receptors in the nucleus accumbens. Peptides. vol 37. issue 2. 2014-06-23. PMID:22885169. |
additionally, d1 and d2 dopamine receptors in the nucleus accumbens (nac) have critical roles in motivation and reward. |
2014-06-23 |
2023-08-12 |
rat |
| Seyedeh-Najmeh Katebi, Yasaman Razavi, Shabnam Zeighamy Alamdary, Fariba Khodagholi, Abbas Haghparas. Morphine could increase apoptotic factors in the nucleus accumbens and prefrontal cortex of rat brain's reward circuitry. Brain research. vol 1540. 2014-06-23. PMID:24096212. |
morphine could increase apoptotic factors in the nucleus accumbens and prefrontal cortex of rat brain's reward circuitry. |
2014-06-23 |
2023-08-12 |
rat |
| Seyedeh-Najmeh Katebi, Yasaman Razavi, Shabnam Zeighamy Alamdary, Fariba Khodagholi, Abbas Haghparas. Morphine could increase apoptotic factors in the nucleus accumbens and prefrontal cortex of rat brain's reward circuitry. Brain research. vol 1540. 2014-06-23. PMID:24096212. |
the nucleus accumbens (nac) and prefrontal cortex (pfc) are two parts of neuronal reward circuit involved in motivated and goal-directed behaviors. |
2014-06-23 |
2023-08-12 |
rat |
| Masago Ishikawa, Mami Otaka, Peter A Neumann, Zhijian Wang, James M Cook, Oliver M Schlüter, Yan Dong, Yanhua H Huan. Exposure to cocaine regulates inhibitory synaptic transmission from the ventral tegmental area to the nucleus accumbens. The Journal of physiology. vol 591. issue 19. 2014-06-20. PMID:23918773. |
synaptic projections from the ventral tegmental area (vta) to the nucleus accumbens (nac) make up the backbone of the brain reward pathway, a neural circuit that mediates behavioural responses elicited by natural rewards as well as by cocaine and other drugs of abuse. |
2014-06-20 |
2023-08-12 |
rat |
| Laura N Smith, Jakub P Jedynak, Miles R Fontenot, Carly F Hale, Karen C Dietz, Makoto Taniguchi, Feba S Thomas, Benjamin C Zirlin, Shari G Birnbaum, Kimberly M Huber, Mark J Thomas, Christopher W Cowa. Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration. Neuron. vol 82. issue 3. 2014-06-20. PMID:24811383. |
we find that fmrp functions in the adult nucleus accumbens (nac), a critical addiction-related brain region, to mediate behavioral sensitization but not cocaine reward. |
2014-06-20 |
2023-08-13 |
mouse |
| Jackson J Cone, James E McCutcheon, Mitchell F Roitma. Ghrelin acts as an interface between physiological state and phasic dopamine signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 14. 2014-05-22. PMID:24695709. |
brief, high-concentration (phasic) spikes in nucleus accumbens dopamine critically participate in aspects of food reward. |
2014-05-22 |
2023-08-13 |
rat |