| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ronny N Gentry, Brian Lee, Matthew R Roesc. Phasic dopamine release in the rat nucleus accumbens predicts approach and avoidance performance. Nature communications. vol 7. 2018-08-27. PMID:27786172. |
using a combined approach-avoidance task, we measured phasic da release in the nucleus accumbens (nac) of rats during presentation of cues that predicted reward, punishment or neutral outcomes and investigated individual differences based on avoidance performance. |
2018-08-27 |
2023-08-13 |
rat |
| Aimilia Lydia Kalafateli, Daniel Vallöf, Julia Winsa Jörnulf, Markus Heilig, Elisabet Jerlha. A cannabinoid receptor antagonist attenuates ghrelin-induced activation of the mesolimbic dopamine system in mice. Physiology & behavior. vol 184. 2018-08-01. PMID:29221808. |
reward modulation involves the mesolimbic dopamine system, consisting of the ventral tegmental area (vta) dopamine neurons targeting nucleus accumbens (nac), a system that ghrelin activates through vta-dependent mechanisms. |
2018-08-01 |
2023-08-13 |
mouse |
| Ingrid Nylander, Aniruddha Todkar, Linnea Granholm, Maria Vrettou, Megha Bendre, Wout Boon, Henrik Andershed, Catherine Tuvblad, Kent W Nilsson, Erika Comasc. Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. Molecular neurobiology. vol 54. issue 8. 2018-07-17. PMID:27709495. |
in rats, fkbp5 expression in the nucleus accumbens and ventral tegmental area, core regions of the reward system, was affected in a region-dependent manner and in opposite direction by maternal separation and alcohol drinking. |
2018-07-17 |
2023-08-13 |
rat |
| Kejing Yuan, Huan Sheng, Jiaojiao Song, Li Yang, Dongyang Cui, Qianqian Ma, Wen Zhang, Bin Lai, Ming Chen, Ping Zhen. Morphine treatment enhances glutamatergic input onto neurons of the nucleus accumbens via both disinhibitory and stimulating effect. Addiction biology. vol 22. issue 6. 2018-07-16. PMID:27549902. |
the nucleus accumbens (nac) is an important site where morphine treatment produces its reinforcing effect on reward. |
2018-07-16 |
2023-08-13 |
Not clear |
| Michael C Salling, Christopher J Hodge, Kelly E Psilos, Vallari R Eastman, Sara P Faccidomo, Clyde W Hodg. Cue-induced reinstatement of alcohol-seeking behavior is associated with increased CaMKII T286 phosphorylation in the reward pathway of mice. Pharmacology, biochemistry, and behavior. vol 163. 2018-07-10. PMID:29100991. |
a variety of plasticity events require activation of calcium calmodulin-dependent protein kinase ii (camkii) in components of the reward pathway, such as the nucleus accumbens and amygdala. |
2018-07-10 |
2023-08-13 |
mouse |
| Chayaporn Reakkamnuan, Dania Cheaha, Ekkasit Kumarnsi. Nucleus accumbens local field potential power spectrums, phase-amplitude couplings and coherences following morphine treatment. Acta neurobiologiae experimentalis. vol 77. issue 3. 2018-07-06. PMID:29182612. |
however, neural signaling in the nucleus accumbens (nac) that might clarify reward process remained to be investigated. |
2018-07-06 |
2023-08-13 |
mouse |
| Ali Siahposht-Khachaki, Somayeh Ezzatpanah, Yasaman Razavi, Abbas Haghparas. NMDA receptor dependent changes in c-fos and p-CREB signaling following extinction and reinstatement of morphine place preference. Neuroscience letters. vol 662. 2018-06-29. PMID:29054430. |
neural circuitry comprising the ventral tegmental area, nucleus accumbens (nac), prefrontal cortex (pfc) and hippocampus (hip) has a main role in reward phenomena. |
2018-06-29 |
2023-08-13 |
rat |
| Hossein Khaleghzadeh-Ahangar, Abbas Haghparas. Intra-accumbal Cannabinoid Agonist Attenuated Reinstatement but not Extinction Period of Morphine-Induced Conditioned Place Preference; Evidence for Different Characteristics of Extinction Period and Reinstatement. Neurochemical research. vol 42. issue 11. 2018-06-26. PMID:28780734. |
the brain reward system consists of the ventral tegmental area that sends its dopaminergic projections to the forebrain, cortical areas, amygdala and largely to the nucleus accumbens (nac). |
2018-06-26 |
2023-08-13 |
rat |
| Olivia Engmann, Benoit Labonté, Amanda Mitchell, Pavel Bashtrykov, Erin S Calipari, Chaggai Rosenbluh, Yong-Hwee E Loh, Deena M Walker, Dominika Burek, Peter J Hamilton, Orna Issler, Rachael L Neve, Gustavo Turecki, Yasmin Hurd, Andrew Chess, Li Shen, Isabelle Mansuy, Albert Jeltsch, Schahram Akbarian, Eric J Nestle. Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biological psychiatry. vol 82. issue 11. 2018-06-21. PMID:28577753. |
exposure to drugs of abuse alters the epigenetic landscape of the brain's reward regions, such as the nucleus accumbens. |
2018-06-21 |
2023-08-13 |
human |
| Hui Ye, Jingxin Wang, Zichuan Tian, Fengfei Ma, James Dowell, Quentin Bremer, Gaoyuan Lu, Brian Baldo, Lingjun L. Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators. Molecular & cellular proteomics : MCP. vol 16. issue 11. 2018-06-19. PMID:28864778. |
previous work has shown that neuropeptide gene expression levels in a forebrain reward site, the nucleus accumbens (nac), were changed by feeding. |
2018-06-19 |
2023-08-13 |
rat |
| Natania A Crane, Stephanie M Gorka, Jessica Weafer, Scott A Langenecker, Harriet de Wit, K Luan Pha. Preliminary Evidence for Disrupted Nucleus Accumbens Reactivity and Connectivity to Reward in Binge Drinkers. Alcohol and alcoholism (Oxford, Oxfordshire). vol 52. issue 6. 2018-06-18. PMID:29016710. |
preliminary evidence for disrupted nucleus accumbens reactivity and connectivity to reward in binge drinkers. |
2018-06-18 |
2023-08-13 |
Not clear |
| Natania A Crane, Stephanie M Gorka, Jessica Weafer, Scott A Langenecker, Harriet de Wit, K Luan Pha. Preliminary Evidence for Disrupted Nucleus Accumbens Reactivity and Connectivity to Reward in Binge Drinkers. Alcohol and alcoholism (Oxford, Oxfordshire). vol 52. issue 6. 2018-06-18. PMID:29016710. |
dysfunctional brain reward circuitry, particularly in the nucleus accumbens (nacc), has been proposed as a risk factor for alcohol use disorder (aud). |
2018-06-18 |
2023-08-13 |
Not clear |
| Saul Martinez-Horta, Frederic Sampedro, Javier Pagonabarraga, Ramón Fernandez-Bobadilla, Juan Marin-Lahoz, Jordi Riba, Jaime Kulisevsk. Non-demented Parkinson's disease patients with apathy show decreased grey matter volume in key executive and reward-related nodes. Brain imaging and behavior. vol 11. issue 5. 2018-06-11. PMID:27730477. |
the second largest cluster of gmv loss was located in the left nucleus accumbens (nacc), a subcortical structure that is a key node of the human reward circuit. |
2018-06-11 |
2023-08-13 |
human |
| Abbas Haghparast, Zahra Fatahi, Reza Arezoomandan, Sara Karimi, Zahra Taslimi, Shahram Zarrabia. Functional roles of orexin/hypocretin receptors in reward circuit. Progress in brain research. vol 235. 2018-06-11. PMID:29054286. |
orexinergic neurons in the lateral hypothalamus project extensively to other brain areas, two most important of which are the ventral tegmental area and the nucleus accumbens that are involved in reward processing. |
2018-06-11 |
2023-08-13 |
Not clear |
| Zahra Fatahi, Bahman Sadeghi, Abbas Haghparas. Involvement of cannabinoid system in the nucleus accumbens on delay-based decision making in the rat. Behavioural brain research. vol 337. 2018-06-08. PMID:28987618. |
the nucleus accumbens (nac) plays a fundamental role in decision making and anticipation of reward. |
2018-06-08 |
2023-08-13 |
rat |
| Michael J Watt, Matthew A Weber, Shaydel R Davies, Gina L Forste. Impact of juvenile chronic stress on adult cortico-accumbal function: Implications for cognition and addiction. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt B. 2018-05-29. PMID:28642080. |
therefore, the goal of this review is to evaluate the current knowledge regarding disruption to executive function and reward processing in adult animals or humans exposed to chronic stress over the juvenile period, and the underlying neurobiology, with particular emphasis on the prefrontal cortex and nucleus accumbens. |
2018-05-29 |
2023-08-13 |
human |
| Hyeran Jang, Kanghoon Jung, Jaehoon Jeong, Sang Ki Park, Jerald D Kralik, Jaeseung Jeon. Nucleus accumbens shell moderates preference bias during voluntary choice behavior. Social cognitive and affective neuroscience. vol 12. issue 9. 2018-05-24. PMID:28992274. |
the nucleus accumbens (nac) shell lies anatomically at a critical intersection within the brain's reward system circuitry, however, its role in voluntary choice behavior remains unclear. |
2018-05-24 |
2023-08-13 |
rat |
| Daniel T Kashima, Brad A Gruete. Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 33. 2018-05-23. PMID:28760987. |
toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior. |
2018-05-23 |
2023-08-13 |
mouse |
| Vivien Günther, Juliane Zimmer, Anette Kersting, Karl-Titus Hoffmann, Donald Lobsien, Thomas Suslo. Automatic processing of emotional facial expressions as a function of social anhedonia. Psychiatry research. Neuroimaging. vol 270. 2018-05-17. PMID:29055240. |
no significant group differences in brain activation emerged in other regions known to be involved in emotion and reward processing, including the amygdala and nucleus accumbens. |
2018-05-17 |
2023-08-13 |
human |
| Steven F Merkel, Allison M Andrews, Evan M Lutton, Roshanak Razmpour, Lee Anne Cannella, Servio H Ramire. Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury. Cell transplantation. vol 26. issue 7. 2018-05-14. PMID:28933216. |
these studies were performed in order to determine whether proinflammatory activity in the nucleus accumbens (nac), a key brain nucleus in the reward pathway, mediates enhanced cocaine-induced cpp in adolescent animals sustaining moderate cci-tbi. |
2018-05-14 |
2023-08-13 |
mouse |