| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Changjiu Zhao, Stephen C Gammi. The circadian gene Nr1d1 in the mouse nucleus accumbens modulates sociability and anxiety-related behaviour. The European journal of neuroscience. vol 48. issue 3. 2019-11-04. PMID:30028550. |
recent work from our laboratory found striking decreases in nr1d1 in the nucleus accumbens (nac) in the maternal condition and indirect evidence that nr1d1 was interacting with numerous addiction and reward-related genes to modulate social reward. |
2019-11-04 |
2023-08-13 |
mouse |
| Max Kenedy Felix Dos Santos, Elaine C Gavioli, Lorena Santa Rosa, Vanessa de Paula Soares-Rachetti, Bruno Lobão-Soare. Craving espresso: the dialetics in classifying caffeine as an abuse drug. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 12. 2019-10-31. PMID:30338342. |
thus, based on a classical action on reward system, caffeine only partially fits its mechanism of action as an abuse drug, especially because previous research does not report a clear effect of dopaminergic activity enhance on nucleus accumbens; despite this, there are reports concerning dopaminergic modulation by caffeine on the striatum. |
2019-10-31 |
2023-08-13 |
human |
| T Chase Francis, Hideaki Yano, Tyler G Demarest, Hui Shen, Antonello Bonc. High-Frequency Activation of Nucleus Accumbens D1-MSNs Drives Excitatory Potentiation on D2-MSNs. Neuron. vol 103. issue 3. 2019-10-31. PMID:31221559. |
however, recent reports indicate enhancing activity of either nucleus accumbens (nac) core msn subtype augments reward, suggesting coincident msn activity may underlie this outcome. |
2019-10-31 |
2023-08-13 |
Not clear |
| Hossein Aleyasin, Meghan E Flanigan, Sam A Golden, Aki Takahashi, Caroline Menard, Madeline L Pfau, Jacob Multer, Jacqueline Pina, Kathryn A McCabe, Naemal Bhatti, Georgia E Hodes, Mitra Heshmati, Rachael L Neve, Eric J Nestler, Elizabeth A Heller, Scott J Russ. Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 26. 2019-10-28. PMID:29891732. |
here, we investigate the cell-type-specific influence of Δfosb, a transcription factor known to regulate a range of reward and motivated behaviors, acting in the nucleus accumbens (nac), a key reward region, in male aggression in mice. |
2019-10-28 |
2023-08-13 |
mouse |
| Manasi Iyer, Rachel A Essner, Bernhard Klingenberg, Matthew E Carte. Identification of discrete, intermingled hypocretin neuronal populations. The Journal of comparative neurology. vol 526. issue 18. 2019-10-28. PMID:30019757. |
these neurons project throughout the brain, including to neural populations that regulate wakefulness, such as the locus coeruleus (lc) and tuberomammilary nucleus (tmn), as well as to populations that regulate reward, such as the nucleus accumbens (nac) and ventral tegmental area (vta). |
2019-10-28 |
2023-08-13 |
Not clear |
| Hannah M Cates, Elizabeth A Heller, Casey K Lardner, Immanuel Purushothaman, Catherine J Peña, Deena M Walker, Michael E Cahill, Rachael L Neve, Li Shen, Rosemary C Bagot, Eric J Nestle. Transcription Factor E2F3a in Nucleus Accumbens Affects Cocaine Action via Transcription and Alternative Splicing. Biological psychiatry. vol 84. issue 3. 2019-10-07. PMID:29397901. |
lasting changes in gene expression in brain reward regions, including nucleus accumbens (nac), contribute to persistent functional changes in the addicted brain. |
2019-10-07 |
2023-08-13 |
Not clear |
| Michael E Cahill, Caleb J Browne, Junshi Wang, Peter J Hamilton, Yan Dong, Eric J Nestle. Withdrawal from repeated morphine administration augments expression of the RhoA network in the nucleus accumbens to control synaptic structure. Journal of neurochemistry. vol 147. issue 1. 2019-10-02. PMID:30071134. |
the nucleus accumbens (nac) is a critical brain reward region that mediates the rewarding effects of drugs of abuse, including those of morphine and other opiates. |
2019-10-02 |
2023-08-13 |
Not clear |
| Brandon L Warren, Leslie R Whitake. Parvalbumin-Expressing Neurons in the Nucleus Accumbens: A New Player in Amphetamine Sensitization and Reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 5. 2019-09-18. PMID:29162905. |
parvalbumin-expressing neurons in the nucleus accumbens: a new player in amphetamine sensitization and reward. |
2019-09-18 |
2023-08-13 |
Not clear |
| Sean B Ostlund, Yijun Cu. Not worth the wait: cocaine alters reward processing in the nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 12. 2019-09-18. PMID:29844476. |
not worth the wait: cocaine alters reward processing in the nucleus accumbens. |
2019-09-18 |
2023-08-13 |
Not clear |
| Jia Cheng, Gali Umschweif, Jenny Leung, Yotam Sagi, Paul Greengar. HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors. Neuron. vol 101. issue 4. 2019-08-26. PMID:30638901. |
cholinergic interneurons (chis) in the nucleus accumbens (nac) have been implicated in drug addiction, reward, and mood disorders. |
2019-08-26 |
2023-08-13 |
mouse |
| Johannes W de Jong, Seyedeh Atiyeh Afjei, Iskra Pollak Dorocic, James R Peck, Christine Liu, Christina K Kim, Lin Tian, Karl Deisseroth, Stephan Lamme. A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System. Neuron. vol 101. issue 1. 2019-08-20. PMID:30503173. |
using in vivo fiber photometry, we simultaneously recorded activity in da terminals in different nucleus accumbens (nac) subnuclei during an aversive and reward conditioning task. |
2019-08-20 |
2023-08-13 |
Not clear |
| Christine Muench, Corinde E Wiers, Carlos R Cortes, Reza Momenan, Falk W Lohof. Dopamine Transporter Gene Methylation is Associated with Nucleus Accumbens Activation During Reward Processing in Healthy but not Alcohol-Dependent Individuals. Alcoholism, clinical and experimental research. vol 42. issue 1. 2019-08-14. PMID:29030974. |
dopamine transporter gene methylation is associated with nucleus accumbens activation during reward processing in healthy but not alcohol-dependent individuals. |
2019-08-14 |
2023-08-13 |
Not clear |
| Katsuyuki Kaneda, Satoshi Deyama, Eiichi Hinoi, Junko Yanagida, Tong Zhang, Hitoki Sasas. [Analyses of cocaine rewarding memories by AAV vector-induced introduction of DREADD system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 153. issue 5. 2019-08-13. PMID:31092754. |
the development and persistence of drug addiction are associated with the activation and adaptation of the brain reward circuitry, which consists of dopaminergic projection from the ventral tegmental area to the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2019-08-13 |
2023-08-13 |
mouse |
| Negar Baharlouei, Abdolrahman Sarihi, Marzieh Moradi, Shahram Zarrabian, Abbas Haghparas. Microinjection of the mGluR2/3 agonist, LY379268, into the nucleus accumbens attenuates extinction latencies and the reinstatement of morphine-induced conditioned place preference in rats. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29462112. |
the nucleus accumbens (nac), which is one of the important areas involved in the reward circuitry, also expresses these receptors. |
2019-07-31 |
2023-08-13 |
rat |
| Hossein Khaleghzadeh-Ahangar, Fariba Khodagholi, Fatemeh Shaerzadeh, Abbas Haghparas. Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats. Brain research bulletin. vol 142. 2019-07-30. PMID:30170186. |
brain reward and motivation circuit begin from the ventral tegmental area (vta) that its dopaminergic terminals project to various regions of the brain including the nucleus accumbens (nac). |
2019-07-30 |
2023-08-13 |
rat |
| Kaustubh Supekar, John Kochalka, Marie Schaer, Holly Wakeman, Shaozheng Qin, Aarthi Padmanabhan, Vinod Meno. Deficits in mesolimbic reward pathway underlie social interaction impairments in children with autism. Brain : a journal of neurology. vol 141. issue 9. 2019-07-17. PMID:30016410. |
we reliably identify white matter tracts linking-the nucleus accumbens and the ventral tegmental area-key subcortical nodes of the mesolimbic reward pathway, and provide reproducible evidence for structural aberrations in these tracts in children with autism spectrum disorder. |
2019-07-17 |
2023-08-13 |
Not clear |
| Sarah M Tashjian, Adriana Galvá. The Role of Mesolimbic Circuitry in Buffering Election-Related Distress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 11. 2019-07-05. PMID:29431648. |
we used functional magnetic resonance imaging and psychological measures to test the hypotheses that neural response to reward, probing the nucleus accumbens (nacc) and medial prefrontal cortex (mpfc), and social support would ameliorate the effects of election distress among those who felt negatively affected by the result. |
2019-07-05 |
2023-08-13 |
human |
| Taylor A Gentile, Steven J Simmons, Christopher S Tallarida, Shu Su, Slava Rom, Mia N Watson, Allen B Reitz, Raghava Potula, Scott M Rawl. Synthetic cathinone MDPV enhances reward function through purinergic P2X7 receptor-dependent pathway and increases P2X7 gene expression in nucleus accumbens. Drug and alcohol dependence. vol 197. 2019-07-01. PMID:30754021. |
synthetic cathinone mdpv enhances reward function through purinergic p2x7 receptor-dependent pathway and increases p2x7 gene expression in nucleus accumbens. |
2019-07-01 |
2023-08-13 |
Not clear |
| Daniel Knowland, Byung Kook Li. Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:29309799. |
in particular, areas such as the ventral tegmental area (vta), nucleus accumbens (nac), and ventral pallidum (vp) are thought to generally promote reward, with the medial prefrontal cortex (mpfc) providing top-down control of reward seeking. |
2019-06-24 |
2023-08-13 |
Not clear |
| David A Seminowicz, Bethany Remeniuk, Samuel R Krimmel, Michael T Smith, Frederick S Barrett, Andreas B Wulff, Andrew J Furman, Stephan Geuter, Martin A Lindquist, Michael R Irwin, Patrick H Fina. Pain-related nucleus accumbens function: modulation by reward and sleep disruption. Pain. vol 160. issue 5. 2019-06-12. PMID:30753171. |
pain-related nucleus accumbens function: modulation by reward and sleep disruption. |
2019-06-12 |
2023-08-13 |
human |