| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weichen Song, Yifeng Shen, Yanhua Zhang, Sufang Peng, Ran Zhang, Ailing Ning, Huafang Li, Xia Li, Guan Ning Lin, Shunying Y. Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats. BMC medical informatics and decision making. vol 19. issue Suppl 6. 2020-08-04. PMID:31856805. |
nucleus accumbens (nac) is a vital brain region for the process of reward and stress, whereas microrna plays a crucial role in depression pathology. |
2020-08-04 |
2023-08-13 |
rat |
| Amanda K Fakira, Emily G Peck, Yutong Liu, Lindsay M Lueptow, Nikita A Trimbake, Ming-Hu Han, Erin S Calipari, Lakshmi A Dev. The role of the neuropeptide PEN receptor, GPR83, in the reward pathway: Relationship to sex-differences. Neuropharmacology. vol 157. 2020-07-21. PMID:31199956. |
gpr83, the receptor for the neuropeptide pen, exhibits high expression in the nucleus accumbens of the human and rodent brain, suggesting that it plays a role in modulating the mesolimbic reward pathway. |
2020-07-21 |
2023-08-13 |
mouse |
| Amanda K Fakira, Emily G Peck, Yutong Liu, Lindsay M Lueptow, Nikita A Trimbake, Ming-Hu Han, Erin S Calipari, Lakshmi A Dev. The role of the neuropeptide PEN receptor, GPR83, in the reward pathway: Relationship to sex-differences. Neuropharmacology. vol 157. 2020-07-21. PMID:31199956. |
using the morphine conditioned place preference model, we identify sex differences in morphine reward-learning, show that gpr83 is upregulated in the nucleus accumbens following morphine conditioned place preference, and show that shrna-mediated knockdown of gpr83 in the nucleus accumbens leads to attenuation morphine reward. |
2020-07-21 |
2023-08-13 |
mouse |
| Michelle Corkrum, Ana Covelo, Justin Lines, Luigi Bellocchio, Marc Pisansky, Kelvin Loke, Ruth Quintana, Patrick E Rothwell, Rafael Lujan, Giovanni Marsicano, Eduardo D Martin, Mark J Thomas, Paulo Kofuji, Alfonso Araqu. Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity. Neuron. vol 105. issue 6. 2020-07-14. PMID:31954621. |
we show that in freely behaving mice, astrocytes in the nucleus accumbens (nac), a key reward center in the brain, respond with ca |
2020-07-14 |
2023-08-13 |
mouse |
| Joseph P Hennessee, Nicco Reggente, Michael S Cohen, Jesse Rissman, Alan D Castel, Barbara J Knowlto. White matter integrity in brain structures supporting semantic processing is associated with value-directed remembering in older adults. Neuropsychologia. vol 129. 2020-07-13. PMID:30986420. |
however, unlike prior findings in younger adults, older adults' memory for high value-items was not significantly correlated with the structural integrity of the uncinate fasciculus, nor with the strength of anatomical connectedness between the bilateral nucleus accumbens to ventral tegmental area reward pathway. |
2020-07-13 |
2023-08-13 |
Not clear |
| Wei Chen, Juan Li, Jun Liu, Dalei Wang, Lijuan Ho. Aerobic Exercise Improves Food Reward Systems in Obese Rats via Insulin Signaling Regulation of Dopamine Levels in the Nucleus Accumbens. ACS chemical neuroscience. vol 10. issue 6. 2020-07-07. PMID:31009571. |
aerobic exercise improves food reward systems in obese rats via insulin signaling regulation of dopamine levels in the nucleus accumbens. |
2020-07-07 |
2023-08-13 |
rat |
| Wei Chen, Juan Li, Jun Liu, Dalei Wang, Lijuan Ho. Aerobic Exercise Improves Food Reward Systems in Obese Rats via Insulin Signaling Regulation of Dopamine Levels in the Nucleus Accumbens. ACS chemical neuroscience. vol 10. issue 6. 2020-07-07. PMID:31009571. |
insufficient food reward caused by dopamine signaling dysfunction in the nucleus accumbens is an important contributor to obesity and may be associated with insulin signaling. |
2020-07-07 |
2023-08-13 |
rat |
| Wei Chen, Juan Li, Jun Liu, Dalei Wang, Lijuan Ho. Aerobic Exercise Improves Food Reward Systems in Obese Rats via Insulin Signaling Regulation of Dopamine Levels in the Nucleus Accumbens. ACS chemical neuroscience. vol 10. issue 6. 2020-07-07. PMID:31009571. |
therefore, we hypothesized that aerobic exercise may increase dopamine levels in the nucleus accumbens through insulin signaling, thus improving food reward in obesity. |
2020-07-07 |
2023-08-13 |
rat |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (nac) shell and increasing nac shell bdnf is sufficient to enhance ethanol reward in naïve wistar rats. |
2020-06-30 |
2023-08-13 |
rat |
| Mireia Hernández, María-Ángeles Palomar-García, Benito Nohales-Nieto, Gustau Olcina-Sempere, Esteban Villar-Rodríguez, Raúl Pastor, César Ávila, Maria-Antònia Parce. Separate Contribution of Striatum Volume and Pitch Discrimination to Individual Differences in Music Reward. Psychological science. vol 30. issue 9. 2020-06-22. PMID:31340130. |
the analysis of both groups together showed that sensitivity to music reward correlated negatively with the volume of both the caudate and nucleus accumbens and correlated positively with pitch-discrimination abilities. |
2020-06-22 |
2023-08-13 |
Not clear |
| Noelia Martínez-Molina, Ernest Mas-Herrero, Antoni Rodríguez-Fornells, Robert J Zatorre, Josep Marco-Pallaré. White Matter Microstructure Reflects Individual Differences in Music Reward Sensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 25. 2020-06-18. PMID:31000588. |
these individual differences in music reward sensitivity are driven by variability in functional connectivity between the nucleus accumbens (nacc), a key structure of the reward system, and the right superior temporal gyrus (stg). |
2020-06-18 |
2023-08-13 |
human |
| Alexandra M Yaw, Rebecca A Prosser, Piet C Jones, Benjamin J Garcia, Daniel A Jacobson, J David Glas. Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice. Behavioural brain research. vol 367. 2020-06-08. PMID:30910707. |
this study, utilizing a murine (c57bl/6j) oral cocaine model, examines the effects of paternal cocaine exposure on fundamental characteristics of offspring reward responses, including: 1) the extent of cocaine-induced effects after different durations of sire drug withdrawal; 2) sex- and drug-dependent differences in f1 reward preference; 3) effects on second generation (f2) cocaine preference; and 4) corresponding changes in reward area (nucleus accumbens) mrna expression. |
2020-06-08 |
2023-08-13 |
mouse |
| Meike C Sieburg, Joseph J Ziminski, Gabriella Margetts-Smith, Hayley M Reeve, Leonie S Brebner, Hans S Crombag, Eisuke Koy. Reward Devaluation Attenuates Cue-Evoked Sucrose Seeking and Is Associated with the Elimination of Excitability Differences between Ensemble and Non-ensemble Neurons in the Nucleus Accumbens. eNeuro. vol 6. issue 6. 2020-06-03. PMID:31699890. |
reward devaluation attenuates cue-evoked sucrose seeking and is associated with the elimination of excitability differences between ensemble and non-ensemble neurons in the nucleus accumbens. |
2020-06-03 |
2023-08-13 |
Not clear |
| Caroline E Strong, Katherine N Wright, Mohamed Kabba. Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density. eNeuro. vol 6. issue 6. 2020-06-03. PMID:31740575. |
to investigate structural plasticity in a brain region involved in reward, nucleus accumbens dendritic spine morphology was examined. |
2020-06-03 |
2023-08-13 |
human |
| Grazia Mirabito, Zinat Taiwo, Matt Bezdek, Sharee N Ligh. Fronto-striatal activity predicts anhedonia and positive empathy subtypes. Brain imaging and behavior. vol 13. issue 6. 2020-05-18. PMID:30868401. |
the dorsolateral prefrontal cortex, globus pallidus, and nucleus accumbens are important components of the reward circuit in the brain; and prior research suggests individuals with damage to these regions feel less pleasure (i.e., are anhedonic). |
2020-05-18 |
2023-08-13 |
human |
| Zhi Li, Yi Wang, Chao Yan, Eric F C Cheung, Anna R Docherty, Pak C Sham, Raquel E Gur, Ruben C Gur, Raymond C K Cha. Inheritance of Neural Substrates for Motivation and Pleasure. Psychological science. vol 30. issue 8. 2020-05-07. PMID:31318629. |
in the present study, we examined the hemodynamic activation of the nucleus accumbens (nacc), a key hub of the reward system, in 86 healthy monozygotic twins and 88 healthy dizygotic twins during a monetary-incentive-delay task. |
2020-05-07 |
2023-08-13 |
human |
| Michael Q Steinman, Natalia Duque-Wilckens, Brian C Traino. Complementary Neural Circuits for Divergent Effects of Oxytocin: Social Approach Versus Social Anxiety. Biological psychiatry. vol 85. issue 10. 2020-04-13. PMID:30503164. |
evidence from several sources supports the premise that ot acting within the nucleus accumbens and ventral tegmental area facilitates social reward and approach behavior. |
2020-04-13 |
2023-08-13 |
Not clear |
| Jeremy F Huckins, Babatunde Adeyemo, Fran M Miezin, Jonathan D Power, Evan M Gordon, Timothy O Laumann, Todd F Heatherton, Steven E Petersen, William M Kelle. Reward-related regions form a preferentially coupled system at rest. Human brain mapping. vol 40. issue 2. 2020-04-07. PMID:30251766. |
peaks of connectivity from seed-based rsfc patterns for the nucleus accumbens (nacc) and orbitofrontal cortex (ofc) were used to identify candidate reward regions which were merged with a previously used set of regions (power et al., 2011). |
2020-04-07 |
2023-08-13 |
human |
| Pan Zhang, Laura S Moye, Bruce R Southey, Isaac Dripps, Jonathan V Sweedler, Amynah Pradhan, Sandra L Rodriguez-Za. Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31129808. |
using rna-seq profiles, gene networks were inferred in the trigeminal ganglia (tg), a central nervous system region associated with pain signaling, and in the nucleus accumbens (nac), a region associated with reward dependency. |
2020-04-06 |
2023-08-13 |
mouse |
| Julianna Kardos, Árpád Dobolyi, Zsolt Szabó, Ágnes Simon, Guillaume Lourmet, Miklós Palkovits, László Héj. Molecular Plasticity of the Nucleus Accumbens Revisited-Astrocytic Waves Shall Rise. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31134458. |
part of the ventral striatal division, the nucleus accumbens (nac) drives the circuit activity of an entire macrosystem about reward like a "flagship," signaling and leading diverse conducts. |
2020-04-06 |
2023-08-13 |
Not clear |