| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David A Seminowicz, Bethany Remeniuk, Samuel R Krimmel, Michael T Smith, Frederick S Barrett, Andreas B Wulff, Andrew J Furman, Stephan Geuter, Martin A Lindquist, Michael R Irwin, Patrick H Fina. Pain-related nucleus accumbens function: modulation by reward and sleep disruption. Pain. vol 160. issue 5. 2019-06-12. PMID:30753171. |
the nucleus accumbens (nac) has been implicated in sleep, reward, and pain modulation, but the relationship between these functional roles is unclear. |
2019-06-12 |
2023-08-13 |
human |
| Mahsaneh Vatankhah, Abdolrahman Sarihi, Alireza Komaki, Siamak Shahidi, Abbas Haghparas. AMN082-a metabotropic glutamate receptor type 7 allosteric agonist in the NAc facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Brain research bulletin. vol 140. 2019-06-04. PMID:29605484. |
nucleus accumbens (nac) plays a primary role in opioid reward. |
2019-06-04 |
2023-08-13 |
rat |
| Erin W Noye Tuplin, Matthew R Holaha. Exploring time-dependent changes in conditioned place preference for food reward and associated changes in the nucleus accumbens. Behavioural brain research. vol 361. 2019-06-04. PMID:30576721. |
exploring time-dependent changes in conditioned place preference for food reward and associated changes in the nucleus accumbens. |
2019-06-04 |
2023-08-13 |
rat |
| María S García-Gutiérrez, Francisco Navarrete, Jorge Laborda, Jorge Manzanare. Deletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice. Biochemical pharmacology. vol 158. 2019-06-03. PMID:30268817. |
quantitative real time polymerase chain reaction (qpcr) studies were carried out to evaluate alterations in targets closely related to da neurotransmission in the reward system, tyrosine hydroxylase (th) in the ventral tegmental area (vta), and μ-opioid receptor (oprm1) in the nucleus accumbens (nac). |
2019-06-03 |
2023-08-13 |
mouse |
| Stan B Floresco, David R Montes, Maric M T Tse, Mieke van Holstei. Differential Contributions of Nucleus Accumbens Subregions to Cue-Guided Risk/Reward Decision Making and Implementation of Conditional Rules. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 8. 2019-05-20. PMID:29348192. |
the nucleus accumbens (nac) is a key node within corticolimbic circuitry for guiding action selection and cost/benefit decision making in situations involving reward uncertainty. |
2019-05-20 |
2023-08-13 |
rat |
| b' Przemys\\xc5\\x82aw Kowia\\xc5\\x84ski, Gra\\xc5\\xbcyna Lietzau, Aleksandra Steliga, Ewelina Czuba, Beata Ludkiewicz, Monika Wa\\xc5\\x9bkow, Jan H Spodnik, Janusz Mory\\xc5\\x9. Nicotine-induced CREB and DeltaFosB activity is modified by caffeine in the brain reward system of the rat. Journal of chemical neuroanatomy. vol 88. 2019-05-14. PMID:29100904.' |
we aimed at determining the effect of caffeine and nicotine, applied separately or simultaneously, on activation of six structures of the brain reward system: nucleus accumbens (nac), ventral tegmental area (vta), amygdala (amg), hippocampus (hip), medial prefrontal cortex (mpfr) and dorsal striatum (cdp) in the adult male wistar rats. |
2019-05-14 |
2023-08-13 |
rat |
| India A Reddy, Nicholas K Smith, Kevin Erreger, Dipanwita Ghose, Christine Saunders, Daniel J Foster, Brandon Turner, Amanda Poe, Vance L Albaugh, Owen McGuinness, Troy A Hackett, Brad A Grueter, Naji N Abumrad, Charles Robb Flynn, Aurelio Gall. Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward. PLoS biology. vol 16. issue 7. 2019-05-06. PMID:30048457. |
viral restoration of tgr5 in the nucleus accumbens of tgr5 knockout animals is sufficient to restore cocaine reward, centrally localizing this tgr5-mediated modulation. |
2019-05-06 |
2023-08-13 |
mouse |
| Shannon L Cole, Mike J F Robinson, Kent C Berridg. Optogenetic self-stimulation in the nucleus accumbens: D1 reward versus D2 ambivalence. PloS one. vol 13. issue 11. 2019-04-23. PMID:30496206. |
optogenetic self-stimulation in the nucleus accumbens: d1 reward versus d2 ambivalence. |
2019-04-23 |
2023-08-13 |
mouse |
| Eleanor J Paul, Eliza Kalk, Kyoko Tossell, Elaine E Irvine, Nicholas P Franks, William Wisden, Dominic J Withers, James Leiper, Mark A Ungles. nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta. eNeuro. vol 5. issue 5. 2019-04-19. PMID:30456293. |
gaba neurons in the vta and snc play key roles in reward and aversion through their local inhibitory control of dopamine neuron activity and through long-range projections to several target regions including the nucleus accumbens. |
2019-04-19 |
2023-08-13 |
mouse |
| Britny A Hildebrandt, Elaine B Sinclair, Cheryl L Sisk, Kelly L Klum. Exploring reward system responsivity in the nucleus accumbens across chronicity of binge eating in female rats. The International journal of eating disorders. vol 51. issue 8. 2019-04-18. PMID:30058183. |
exploring reward system responsivity in the nucleus accumbens across chronicity of binge eating in female rats. |
2019-04-18 |
2023-08-13 |
rat |
| Fabrizio Sanna, Laura Poddighe, Maria Pina Serra, Marianna Boi, Jessica Bratzu, Francesco Sanna, Maria Giuseppa Corda, Osvaldo Giorgi, Maria Rosaria Melis, Antonio Argiolas, Marina Quart. c-Fos, ΔFosB, BDNF, trkB and Arc Expression in the Limbic System of Male Roman High- and Low-Avoidance Rats that Show Differences in Sexual Behavior: Effect of Sexual Activity. Neuroscience. vol 396. 2019-04-01. PMID:30423358. |
since sexual activity is a natural reward that induces neural activation and synaptic plastic changes in limbic brain areas, we studied whether the differences in sexual activity between these rat lines are accompanied by changes in the expression of markers of neural activation and plasticity, i.e., c-fos, Δfosb (a truncated form of fosb), brain-derived neurotrophic factor (bdnf) and its tyrosine kinase receptor b (trkb) and activity regulated cytoskeleton-associated (arc) protein in the ventral tegmental area (vta), nucleus accumbens (acb) (core and shell) and medial prefrontal cortex (mpfc) of sexually naïve and experienced rha and rla rats by western blot and/or immunohistochemistry. |
2019-04-01 |
2023-08-13 |
rat |
| Katayoun Sedaghat, Zahra Yousefian, Abbas Ali Vafaei, Ali Rashidy-Pour, Houman Parsaei, Ali Khaleghian, Sara Choobda. Mesolimbic dopamine system and its modulation by vitamin D in a chronic mild stress model of depression in the rat. Behavioural brain research. vol 356. 2019-03-22. PMID:30144460. |
depression, a common mood disorder, involves anhedonia and defects in reward circuits and mesolimbic dopamine transmission in the striatum and nucleus accumbens (nac). |
2019-03-22 |
2023-08-13 |
rat |
| M E Cahill, D M Walker, A M Gancarz, Z J Wang, C K Lardner, R C Bagot, R L Neve, D M Dietz, E J Nestle. The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling. Molecular psychiatry. vol 23. issue 6. 2019-03-18. PMID:28555077. |
the nucleus accumbens (nac) is a primary brain reward region composed predominantly of medium spiny neurons (msns). |
2019-03-18 |
2023-08-13 |
Not clear |
| Lauren E Sherman, Patricia M Greenfield, Leanna M Hernandez, Mirella Daprett. Peer Influence Via Instagram: Effects on Brain and Behavior in Adolescence and Young Adulthood. Child development. vol 89. issue 1. 2019-03-12. PMID:28612930. |
popular photographs elicited greater activity in multiple brain regions, including the nucleus accumbens (nacc), a hub of the brain's reward circuitry. |
2019-03-12 |
2023-08-13 |
human |
| Christian Buchel, Stephan Miedl, Christian Sprenge. Hedonic processing in humans is mediated by an opioidergic mechanism in a mesocorticolimbic system. eLife. vol 7. 2019-03-12. PMID:30444488. |
it has been hypothesized that the pleasure of a reward in humans is mediated by an opioidergic system involving the hypothalamus, nucleus accumbens and the amygdala. |
2019-03-12 |
2023-08-13 |
human |
| Michele M Moraes, Patrícia C R Rabelo, Valéria A Pinto, Washington Pires, Samuel P Wanner, Raphael E Szawka, Danusa D Soare. Auditory stimulation by exposure to melodic music increases dopamine and serotonin activities in rat forebrain areas linked to reward and motor control. Neuroscience letters. vol 673. 2019-03-11. PMID:29499311. |
here, we investigated the effects of exposure to melodic music on the concentrations of dopamine (da), serotonin (5-ht) and their respective metabolites in the caudate-putamen (cpu) and nucleus accumbens (nacc), areas linked to reward and motor control. |
2019-03-11 |
2023-08-13 |
rat |
| Mahsaneh Vatankhah, Saeideh Karimi-Haghighi, Abdolrahman Sarihi, Abbas Haghparas. Intra-accumbal administration of AMN082, a metabotropic glutamate receptor type 7 allosteric agonist, inhibits the acquisition but not the expression of morphine-induced conditioned place preference in rats. Neuroscience letters. vol 681. 2019-03-11. PMID:29800675. |
the nucleus accumbens (nac) plays a primary role in opioid reward. |
2019-03-11 |
2023-08-13 |
rat |
| S Mohammad Ahmadi Soleimani, Mohammad Hossein Mohamadi M A H, Mohammad Reza Raoufy, Hossein Azizi, Mohammad Nasehi, Mohammad Reza Zarrindas. Acute morphine administration alters the power of local field potentials in mesolimbic pathway of freely moving rats: Involvement of dopamine receptors. Neuroscience letters. vol 686. 2019-03-07. PMID:30219483. |
increasing number of evidence support the role of ventral tegmental area (vta) and nucleus accumbens (nac) in mediating the opiate effects as the two critical components of brain reward pathway. |
2019-03-07 |
2023-08-13 |
rat |
| Katherine T Martucci, Nicholas Borg, Kelly H MacNiven, Brian Knutson, Sean C Macke. Altered prefrontal correlates of monetary anticipation and outcome in chronic pain. Pain. vol 159. issue 8. 2019-02-21. PMID:29790868. |
group fmri analyses were conducted to determine predetermined region of interest, nucleus accumbens (nacc) and medial prefrontal cortex (mpfc), responses to potential gains, potential losses, reward outcomes, and punishment outcomes. |
2019-02-21 |
2023-08-13 |
human |
| R M Bastle, R J Oliver, A S Gardiner, N S Pentkowski, F Bolognani, A M Allan, T Chaudhury, M St Peter, N Galles, C Smith, J L Neisewander, N I Perrone-Bizzozer. In silico identification and in vivo validation of miR-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens. Molecular psychiatry. vol 23. issue 2. 2019-02-15. PMID:28044061. |
this small non-coding rna is also highly expressed within the nucleus accumbens (nac), a pivotal brain region underlying reward and motivation. |
2019-02-15 |
2023-08-13 |
mouse |