| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suzanne M Shdo, Kamalini G Ranasinghe, Kelly A Gola, Clinton J Mielke, Paul V Sukhanov, Bruce L Miller, Katherine P Ranki. Deconstructing empathy: Neuroanatomical dissociations between affect sharing and prosocial motivation using a patient lesion model. Neuropsychologia. vol 116. issue Pt A. 2019-02-07. PMID:28209520. |
prosocial motivation, in contrast, involved structures such as the nucleus accumbens (nacc), caudate head, and inferior frontal gyrus (ifg), which suggests that an individual must maintain the capacity to experience reward, to resolve ambiguity, and to inhibit their own emotional experience in order to effectively engage in spontaneous altruism as a component of their empathic response to others. |
2019-02-07 |
2023-08-13 |
human |
| Jodi R Godfrey, Maylen Perez Diaz, Melanie Pincus, Zsofia Kovacs-Balint, Eric Feczko, Eric Earl, Oscar Miranda-Dominguez, Damien Fair, Mar M Sanchez, Mark E Wilson, Vasiliki Michopoulo. Diet matters: Glucocorticoid-related neuroadaptations associated with calorie intake in female rhesus monkeys. Psychoneuroendocrinology. vol 91. 2019-02-04. PMID:29567621. |
while consumption of an obesogenic diet and chronic stress have both been shown to decrease dopamine 2 receptor (d2r) binding and alter functional connectivity (fc) within the prefrontal cortex (pfc) and the nucleus accumbens (nacc), it remains uncertain how social experience and dietary environment interact to affect reward pathways critical for the regulation of motivated behavior. |
2019-02-04 |
2023-08-13 |
monkey |
| Katsuyuki Kaned. The contribution of neuroplasticity induced in cholinergic neurons of the laterodorsal tegmental nucleus to cocaine addiction. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 37. issue 1. 2019-01-28. PMID:30452815. |
cocaine-induced neuroplasticity in brain reward circuitry consisting of the ventral tegmental area (vta), nucleus accumbens and medial pre- frontal cortex is critical for developing cocaine addiction. |
2019-01-28 |
2023-08-13 |
rat |
| Enith Espinosa, Kathleen S Curti. Increased locomotor activity in estrogen-treated ovariectomized rats is associated with nucleus accumbens dopamine and is not reduced by dietary sodium deprivation. Integrative zoology. vol 13. issue 6. 2019-01-18. PMID:29851282. |
we first determined whether the estrogen-induced increase in locomotion was susceptible to inhibition by a physiological challenge, and next whether it was associated with dopaminergic activation in the central reward area, nucleus accumbens. |
2019-01-18 |
2023-08-13 |
rat |
| Ashley M Kopec, Caroline J Smith, Nathan R Ayre, Sean C Sweat, Staci D Bilb. Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats. Nature communications. vol 9. issue 1. 2019-01-16. PMID:30254300. |
adolescence is a developmental period in which the mesolimbic dopaminergic "reward" circuitry of the brain, including the nucleus accumbens (nac), undergoes significant plasticity. |
2019-01-16 |
2023-08-13 |
rat |
| Staci E Engle, Patrick J Antonellis, Logan S Whitehouse, Ruchi Bansal, Michelle R Emond, James D Jontes, Robert A Kesterson, Kirk Mykytyn, Nicolas F Berbar. A CreER mouse to study melanin concentrating hormone signaling in the developing brain. Genesis (New York, N.Y. : 2000). vol 56. issue 8. 2019-01-10. PMID:29806135. |
most strikingly, compared to the constitutive model, the new mchr1-creer model shows strong expression in adult animals in hypothalamic brain regions involved in feeding behavior but diminished expression in regions involved in reward, such as the nucleus accumbens. |
2019-01-10 |
2023-08-13 |
mouse |
| David Ottenheimer, Jocelyn M Richard, Patricia H Jana. Ventral pallidum encodes relative reward value earlier and more robustly than nucleus accumbens. Nature communications. vol 9. issue 1. 2019-01-08. PMID:30341305. |
ventral pallidum encodes relative reward value earlier and more robustly than nucleus accumbens. |
2019-01-08 |
2023-08-13 |
rat |
| Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestle. Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine. Nature communications. vol 9. issue 1. 2018-12-12. PMID:30089879. |
the role of somatostatin interneurons in nucleus accumbens (nac), a key brain reward region, remains poorly understood due to the fact that these cells account for < 1% of nac neurons. |
2018-12-12 |
2023-08-13 |
Not clear |
| Yadi Li, Wenhua Zhou, Haibo Dong, Wenwen Shen, Jianbing Zhang, Feng Li, Lingjun Zhan. Lower Fractional Anisotropy in the Gray Matter of Amygdala-Hippocampus-Nucleus Accumbens Circuit in Methamphetamine Users: an In Vivo Diffusion Tensor Imaging Study. Neurotoxicity research. vol 33. issue 4. 2018-12-11. PMID:29038922. |
the basolateral amygdala (bla), hippocampal ventral subiculum, and nucleus accumbens (nac) comprise the amygdala-hippocampus-nac (ahn) circuit, which is implicated in drug seeking and reward. |
2018-12-11 |
2023-08-13 |
human |
| Zachary S Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M Walker, Eric M Parise, Marine Salery, Michael E Cahill, Georgia E Hodes, Madeline L Pfau, Hope Kronman, Peter J Hamilton, Orna Issler, Benoit Labonté, Ann E Symonds, Matthew Zucker, Tie Yuan Zhang, Michael J Meaney, Scott J Russo, Li Shen, Rosemary C Bagot, Eric J Nestle. Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29549264. |
we identify estrogen receptor α (erα) as the top regulator of pro-resilient transcriptional changes in the nucleus accumbens (nac), a key brain reward region implicated in depression. |
2018-12-11 |
2023-08-13 |
mouse |
| Rifka C Derman, Carrie R Ferrari. Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs. Neuropharmacology. vol 131. 2018-11-19. PMID:29291424. |
the nucleus accumbens (nac) mediates cue-triggered reward seeking and activity in the nac is enhanced in obesity-susceptible populations. |
2018-11-19 |
2023-08-13 |
human |
| Shi-Yu Peng, Bin Li, Kang Xi, Jian-Jun Wang, Jing-Ning Zh. Presynaptic α Neuroscience letters. vol 665. 2018-11-15. PMID:29195907. |
presynaptic α the nucleus accumbens (nac), integrating information from the prefrontal cortex and limbic structures, plays a critical role in reward and emotion regulation. |
2018-11-15 |
2023-08-13 |
Not clear |
| Laurent Tritschler, Mazen A Kheirbek, Yannick Le Dantec, Indira Mendez-David, Jean-Philippe Guilloux, Charlène Faye, Julie Doan, Thu Ha Pham, René Hen, Denis J David, Alain M Gardie. Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens. Neuroscience research. vol 134. 2018-11-01. PMID:29246683. |
dopamine (da) release in the nucleus accumbens (nacc), which belongs to the reward system, could be a key target of ddg mediating this motivation-related behavior. |
2018-11-01 |
2023-08-13 |
mouse |
| Juhwan Kim, Sueun Lee, Sohi Kang, Tae-Il Jeon, Man-Jong Kang, Tae-Hoon Lee, Yong Sik Kim, Key-Sun Kim, Heh-In Im, Changjong Moo. Regulator of G-Protein Signaling 4 (RGS4) Controls Morphine Reward by Glutamate Receptor Activation in the Nucleus Accumbens of Mouse Brain. Molecules and cells. vol 41. issue 5. 2018-10-30. PMID:29754475. |
regulator of g-protein signaling 4 (rgs4) controls morphine reward by glutamate receptor activation in the nucleus accumbens of mouse brain. |
2018-10-30 |
2023-08-13 |
mouse |
| Matthew Hearing, Nicholas Graziane, Yan Dong, Mark J Thoma. Opioid and Psychostimulant Plasticity: Targeting Overlap in Nucleus Accumbens Glutamate Signaling. Trends in pharmacological sciences. vol 39. issue 3. 2018-10-24. PMID:29338873. |
recent more selective examination of drug-induced plasticity has highlighted that these two drug classes promote an overall reward circuitry signaling overlap through modifying excitatory synapses in the nucleus accumbens - a key constituent of the reward system. |
2018-10-24 |
2023-08-13 |
Not clear |
| Chuchu Qi, Baolin Guo, Keke Ren, Han Yao, Mengmeng Wang, Tangna Sun, Guohong Cai, Haiying Liu, Rui Li, Ceng Luo, Wenting Wang, Shengxi W. Chronic inflammatory pain decreases the glutamate vesicles in presynaptic terminals of the nucleus accumbens. Molecular pain. vol 14. 2018-10-22. PMID:29770746. |
reward system has been proved to be important to nociceptive behavior, and the nucleus accumbens (nac) is a key node in reward circuitry. |
2018-10-22 |
2023-08-13 |
mouse |
| Mrunal Rane, Rohit Manchand. Effects of location and extent of spine clustering on synaptic integration in striatal medium spiny neurons-a computational study. Medical & biological engineering & computing. vol 56. issue 7. 2018-10-15. PMID:29209962. |
the nucleus accumbens (nac) is known widely for its role in the reward circuit, which is dysregulated in a number of psychological disorders. |
2018-10-15 |
2023-08-13 |
Not clear |
| Jia Liu, Karen Dietz, Georgia E Hodes, Scott J Russo, Patrizia Casacci. Widespread transcriptional alternations in oligodendrocytes in the adult mouse brain following chronic stress. Developmental neurobiology. vol 78. issue 2. 2018-10-09. PMID:28884925. |
in concert with these behavioral responses, transcriptional analysis of pfc, and nucleus accumbens (nac)-a brain region critical for reward response-revealed downregulation of transcripts encoding for myelin genes and oligodendrocyte-specific genes. |
2018-10-09 |
2023-08-13 |
mouse |
| Peter J Vollbrecht, Kathryn M Nesbitt, Omar S Mabrouk, Aaron M Chadderdon, Emily M Jutkiewicz, Robert T Kennedy, Carrie R Ferrari. Cocaine and desipramine elicit distinct striatal noradrenergic and behavioral responses in selectively bred obesity-resistant and obesity-prone rats. Behavioural brain research. vol 346. 2018-09-11. PMID:29129597. |
differences in the function of brain reward circuits, including in the nucleus accumbens (nac), have been shown in obesity-prone vs. obesity-resistant populations, leading many researchers to explore the role of striatal dopamine in obesity. |
2018-09-11 |
2023-08-13 |
rat |
| Marjan Sahafzadeh, Saeideh Karimi-Haghighi, Zahra Mousavi, Abbas Haghparas. Role of the orexin receptors within the nucleus accumbens in the drug priming-induced reinstatement of morphine seeking in the food deprived rats. Brain research bulletin. vol 137. 2018-08-31. PMID:29258865. |
the nucleus accumbens (nac) has an important role in the reward system and receives orexinergic projections of the lateral hypothalamus. |
2018-08-31 |
2023-08-13 |
rat |