| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S C Bressler, M J Bau. Sex comparison of neuronal Fos immunoreactivity in the rat vomeronasal projection circuit after chemosensory stimulation. Neuroscience. vol 71. issue 4. 1996-08-22. PMID:8684610. |
finally, chemosensory stimulation augmented fos immunoreactivity in the nucleus accumbens shell and core, two regions receiving dopaminergic afferents which have been implicated in sexual reward. |
1996-08-22 |
2023-08-12 |
human |
| F G Kaddis, N J Uretsky, L J Wallac. DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593597. |
several lines of evidence suggest that activation of both ampa/kainate receptors and dopaminergic receptors in the nucleus accumbens may be required for psychostimulant drug induced reward. |
1996-04-11 |
2023-08-12 |
rat |
| K Blum, P J Sheridan, R C Wood, E R Braverman, T J Chen, D E Coming. Dopamine D2 receptor gene variants: association and linkage studies in impulsive-addictive-compulsive behaviour. Pharmacogenetics. vol 5. issue 3. 1995-10-24. PMID:7550364. |
dopaminergic reward pathways have frequently been implicated in the etiology of addictive behaviour. |
1995-10-24 |
2023-08-12 |
human |
| K Blum, R C Wood, E R Braverman, T J Chen, P J Sherida. The D2 dopamine receptor gene as a predictor of compulsive disease: Bayes' theorem. Functional neurology. vol 10. issue 1. 1995-09-28. PMID:7649500. |
the dopaminergic system, and in particular the dopamine d2 receptor, has been profoundly implicated in reward mechanisms in the meso-limbic circuitry of the brain. |
1995-09-28 |
2023-08-12 |
Not clear |
| M Soyka, P San. Successful treatment with flupenthixol decanoate of a patient with both schizophrenia and alcoholism. Pharmacopsychiatry. vol 28. issue 2. 1995-08-29. PMID:7624388. |
modifications of d2-receptor subtype function have been implicated in psychotic symptoms, and changes in the d1- and d2-receptor function in substance abuse such as cocaine abuse and alcoholism (spealman et al., 1990; 1991; 1992), especially in the mesolimbic dopaminergic reward system. |
1995-08-29 |
2023-08-12 |
Not clear |
| M C Martellotta, A Kuzmin, P Muglia, G L Gessa, W Fratt. Effects of the calcium antagonist isradipine on cocaine intravenous self-administration in rats. Psychopharmacology. vol 113. issue 3-4. 1995-03-20. PMID:7862848. |
these results suggest that isradipine antagonizes the rewarding properties of cocaine, possibly by inhibiting those dopaminergic systems related to reward mechanisms. |
1995-03-20 |
2023-08-12 |
rat |
| D LeMarquand, R O Pihl, C Benkelfa. Serotonin and alcohol intake, abuse, and dependence: findings of animal studies. Biological psychiatry. vol 36. issue 6. 1995-02-01. PMID:7803601. |
ethanol produces transient increases in serotonergic functioning that activate the mesolimbic dopaminergic reward system. |
1995-02-01 |
2023-08-12 |
Not clear |
| A Heinz, L G Schmidt, F M Reischie. Anhedonia in schizophrenic, depressed, or alcohol-dependent patients--neurobiological correlates. Pharmacopsychiatry. vol 27 Suppl 1. 1995-01-04. PMID:7984706. |
these symptoms may be caused by a functional deficit of dopaminergic transmission in the dopaminergic reward system, ascending from the mesencephalon to the ventral striatum (nucleus accumbens). |
1995-01-04 |
2023-08-12 |
Not clear |
| A Heinz, L G Schmidt, F M Reischie. Anhedonia in schizophrenic, depressed, or alcohol-dependent patients--neurobiological correlates. Pharmacopsychiatry. vol 27 Suppl 1. 1995-01-04. PMID:7984706. |
the dopaminergic reward system is functionally and anatomically closely connected with the ascending extrapyramidal pathways from the substantia nigra to the dorsal striatum. |
1995-01-04 |
2023-08-12 |
Not clear |
| A Heinz, L G Schmidt, F M Reischie. Anhedonia in schizophrenic, depressed, or alcohol-dependent patients--neurobiological correlates. Pharmacopsychiatry. vol 27 Suppl 1. 1995-01-04. PMID:7984706. |
in order to further investigate the correlation of anhedonia, psychomotor slowing, and the status of the dopaminergic reward system, the density of striatal dopamine d2-receptors can be measured by ibzm-spect and related to psychomotor slowing and anhedonia in different states of schizophrenic, depressive, and alcohol-dependent patients. |
1995-01-04 |
2023-08-12 |
Not clear |
| M A Bozarth, C M Pudiak, M Morri. Nitric oxide synthesis inhibition does not affect brain stimulation reward. Pharmacology, biochemistry, and behavior. vol 48. issue 2. 1994-10-20. PMID:8090819. |
despite reports that nitric oxide may modulate dopamine release, these data suggest that nitric oxide is not involved in the dopamine-dependent rewarding effect of electrical brain stimulation or the reward facilitation produced by cocaine's enhancement of dopaminergic activity. |
1994-10-20 |
2023-08-12 |
Not clear |
| E P Noble, S T St Jeor, T Ritchie, K Syndulko, S C St Jeor, R J Fitch, R L Brunner, R S Sparke. D2 dopamine receptor gene and cigarette smoking: a reward gene? Medical hypotheses. vol 42. issue 4. 1994-09-26. PMID:8072432. |
in as much as alcohol, cocaine, opiates, nicotine and food are known to increase brain dopamine levels and activate the mesocorticolimbic dopaminergic reward pathways of the brain, it is hypothesized that an inherited deficit of d2 dopamine receptor numbers in brain reward areas of a1 allelic subject predisposes them to substance abuse problems. |
1994-09-26 |
2023-08-12 |
human |
| M A Menza, M H Mar. Parkinson's disease and depression: the relationship to disability and personality. The Journal of neuropsychiatry and clinical neurosciences. vol 6. issue 2. 1994-08-31. PMID:8044039. |
depression was not correlated with novelty seeking, a personality trait related to dopaminergic pleasure and reward systems. |
1994-08-31 |
2023-08-12 |
human |
| D E Comings, D Muhleman, C Ahn, R Gysin, S D Flanaga. The dopamine D2 receptor gene: a genetic risk factor in substance abuse. Drug and alcohol dependence. vol 34. issue 3. 1994-08-12. PMID:8033754. |
dopaminergic reward pathways have frequently been implicated in the etiology of drug addiction. |
1994-08-12 |
2023-08-12 |
human |
| A J Lanç. Reduction of voluntary alcohol intake in the rat by modulation of the dopaminergic mesolimbic system: transplantation of ventral mesencephalic cell suspensions. Neuroscience. vol 58. issue 2. 1994-05-11. PMID:8152544. |
the dopaminergic mesolimbic system plays a major role in the mechanisms of reward and positive reinforcement, and is also known to be a primary target for the action of substances that are self-administered and are considered drugs of abuse. |
1994-05-11 |
2023-08-12 |
rat |
| R Simanto. Chronic morphine alters dopamine transporter density in the rat brain: possible role in the mechanism of drug addiction. Neuroscience letters. vol 163. issue 2. 1994-03-17. PMID:8309616. |
it is suggested, therefore, that chronic morphine treatment has a long-lasting and selective effect on the activity of dopamine transporters in the dopaminergic reward pathway, but not in the striatum. |
1994-03-17 |
2023-08-12 |
rat |
| T Kling-Petersen, K Svensso. A simple computer-based method for performing and analyzing intracranial self-stimulation experiments in rats. Journal of neuroscience methods. vol 47. issue 3. 1994-02-01. PMID:8271820. |
the effects of compounds interacting with dopaminergic neurotransmission is measurable by studying the changes of reward thresholds. |
1994-02-01 |
2023-08-12 |
rat |
| R Sandyk, N Tsagas, P A Anninos, K Derpapa. Magnetic fields mimic the behavioral effects of REM sleep deprivation in humans. The International journal of neuroscience. vol 65. issue 1-4. 1994-01-27. PMID:1341692. |
since "drive"-related behaviors are thought to involve activation of limbic dopaminergic reward sites, rsd may enhance motivational behaviors through an action on limbic dopaminergic functions. |
1994-01-27 |
2023-08-11 |
human |
| R Sandyk, N Tsagas, P A Anninos, K Derpapa. Magnetic fields mimic the behavioral effects of REM sleep deprivation in humans. The International journal of neuroscience. vol 65. issue 1-4. 1994-01-27. PMID:1341692. |
we propose, therefore, that the behavioral and mental effects of treatment with magnetic fields may be mediated via rsd and, by inference, involve activation of limbic dopaminergic reward sites. |
1994-01-27 |
2023-08-11 |
human |
| D Huston-Lyons, M Sarkar, C Kornetsk. Nicotine and brain-stimulation reward: interactions with morphine, amphetamine and pimozide. Pharmacology, biochemistry, and behavior. vol 46. issue 2. 1994-01-27. PMID:8265701. |
these data suggest that the same dopaminergic substrate that supports the positive reinforcing effects of other drugs of abuse also supports nicotine reward. |
1994-01-27 |
2023-08-12 |
rat |