| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C D Blaha, A G Phillip. Application of in vivo electrochemistry to the measurement of changes in dopamine release during intracranial self-stimulation. Journal of neuroscience methods. vol 34. issue 1-3. 1991-01-31. PMID:2147973. |
the pharmacological studies are consistent with a dopaminergic substrate of brain stimulation reward at electrode sites in the vta. |
1991-01-31 |
2023-08-11 |
Not clear |
| O Kofman, S M McGlynn, M C Olmstead, J S Yeoman. Differential effects of atropine, procaine and dopamine in the rat ventral tegmentum on lateral hypothalamic rewarding brain stimulation. Behavioural brain research. vol 38. issue 1. 1990-07-12. PMID:2346616. |
hence, both dopaminergic and muscarinic receptors in ventral tegmentum are involved in lateral hypothalamic brain stimulation reward. |
1990-07-12 |
2023-08-11 |
rat |
| L H Schneide. Orosensory self-stimulation by sucrose involves brain dopaminergic mechanisms. Annals of the New York Academy of Sciences. vol 575. 1990-05-18. PMID:2699194. |
the most convincing body of evidence supporting a role for brain dopaminergic mechanisms in sweet taste reward has been obtained using the sham-feeding rat. |
1990-05-18 |
2023-08-11 |
human |
| W C Hall, R L Talbert, L Ereshefsk. Cocaine abuse and its treatment. Pharmacotherapy. vol 10. issue 1. 1990-04-24. PMID:2179901. |
dopaminergic systems are the principal sites of reward and participate in abstinence symptomatology, putatively through depletion of dopamine and changes in receptor sensitivity and responsiveness. |
1990-04-24 |
2023-08-11 |
Not clear |
| S V Ramana, T Desiraj. Investigation of influence of diazepam, valproate, cyproheptadine and cortisol on the rewarding ventral tegmental self-stimulation behaviour. Indian journal of physiology and pharmacology. vol 33. issue 3. 1990-01-23. PMID:2512254. |
experiments were carried on in the wistar rats having self-stimulation (ss) electrodes implanted chronically in substantia nigra-ventral tegmental area (sn-vta) to examine whether modulations of gabaergic, serotonergic, histaminergic, dopaminergic, and glucocorticoid neuronal receptor functions will affect or not the brain reward system and the ss behaviour. |
1990-01-23 |
2023-08-11 |
rat |
| J Backo. Predicting new effective treatments of alcohol addiction on the basis of their properties of inhibition of noradrenergic activity and/or thromboxane or on the activation of the dopamine reward system and/or beta-endorphin. Medical hypotheses. vol 29. issue 4. 1990-01-05. PMID:2573815. |
on the basis of their properties of noradrenergic and/or thromboxane inhibition, or on their activation of the dopaminergic reward system and/or beta-endorphin, the following substances or treatments are predicted to be effective in treating alcohol or drug addiction: ginger; carbon dioxide; dietary sulfur; methionine; calcium; lhrh; high intensity light; interferon; negative ions; serotonin antagonists such as methysergide and cyproheptadine; guanabenz and guenfacine; antihistamines; head-out water immersion; x-irradiation; and forced unilateral left nostril breathing. |
1990-01-05 |
2023-08-11 |
Not clear |
| A G Phillips, C D Blaha, H C Fibige. Neurochemical correlates of brain-stimulation reward measured by ex vivo and in vivo analyses. Neuroscience and biobehavioral reviews. vol 13. issue 2-3. 1989-12-12. PMID:2530478. |
both data bases provide strong support for a dopaminergic substrate for brain-stimulation reward obtained by electrical stimulation of the ventral tegmental area (vta). |
1989-12-12 |
2023-08-11 |
Not clear |
| A G Phillips, C D Blaha, H C Fibige. Neurochemical correlates of brain-stimulation reward measured by ex vivo and in vivo analyses. Neuroscience and biobehavioral reviews. vol 13. issue 2-3. 1989-12-12. PMID:2530478. |
these pharmacological experiments also are consistent with a dopaminergic substrate of brain-stimulation reward at electrode sites in the vta. |
1989-12-12 |
2023-08-11 |
Not clear |
| R J Beninger, D C Hoffman, E J Mazursk. Receptor subtype-specific dopaminergic agents and conditioned behavior. Neuroscience and biobehavioral reviews. vol 13. issue 2-3. 1989-12-12. PMID:2573022. |
d1 agonists may fail to produce reward effects because they, unlike d2 agonists, directly mask the dopaminergic signal at the d1 receptor. |
1989-12-12 |
2023-08-11 |
Not clear |
| C M Knapp, C Kornetsk. The effects of amfonelic acid alone and in combination with naloxone on brain-stimulation reward. Pharmacology, biochemistry, and behavior. vol 32. issue 4. 1989-11-07. PMID:2572008. |
furthermore, these results suggest that endogenous opioid systems may begin to modulate the effects of afa on the reward system only when a certain level of activation of dopaminergic systems is reached. |
1989-11-07 |
2023-08-11 |
Not clear |
| S Yamagami, K Soejim. Effect of maprotiline combined with conventional neuroleptics against negative symptoms of chronic schizophrenia. Drugs under experimental and clinical research. vol 15. issue 4. 1989-10-23. PMID:2570687. |
these results suggest that maprotiline improves the negative symptoms of schizophrenia by a noradrenaline potentiating action not demonstrated by dopaminergic or serotonergic reward systems. |
1989-10-23 |
2023-08-11 |
Not clear |
| J Backo. Etiology of alcoholism: relevance of prenatal hormonal influences on the brain, anomalous dominance, and neurochemical and pharmacological brain asymmetry. Medical hypotheses. vol 29. issue 1. 1989-08-18. PMID:2664435. |
because of possible prenatal hormonal influences on the brain, leading to anomalous dominance, pharmacological and neurochemical asymmetry, and consequent antisocial personality and phobic anxiety, the subject ingests ethanol for its tension-reducing properties via endorphinergic activation and the dopaminergic reward system. |
1989-08-18 |
2023-08-11 |
human |
| R D Myer. Isoquinolines, beta-carbolines and alcohol drinking: involvement of opioid and dopaminergic mechanisms. Experientia. vol 45. issue 5. 1989-07-07. PMID:2656285. |
finally, it is proposed that the dopaminergic reward pathways which traverse the meso-limbic-forebrain systems of the brain more than likely constitute an integrative anatomical substrate for the adduct-opioid cascade of neuronal events which promote and sustain the aberrant drinking of alcohol. |
1989-07-07 |
2023-08-11 |
rat |
| P P Rompré, R A Wis. Opioid-neuroleptic interaction in brainstem self-stimulation. Brain research. vol 477. issue 1-2. 1989-05-19. PMID:2702479. |
this finding suggested a complete inactivation of the reward mechanism, which might be expected from the interaction of high doses of two drugs that are each known to be capable of producing depolarization inactivation of dopaminergic neurons. |
1989-05-19 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
one thing is clear: dopamine is not the only reward transmitter, and dopaminergic neurons are not the final common path for all rewards. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
it is not consistent with the dopamine hypothesis that dopamine-independent reward sites should exist in these areas, since any reward signals carried to nucleus accumbens or frontal cortex by dopamine fibers would-unless we are to believe that reward "happens" at these sites-have to be carried to the next stage of the circuit by nondopaminergic fibers (there are no dopaminergic cell bodies in any of the dopamine terminal areas). |
1989-04-24 |
2023-08-11 |
Not clear |
| L van Wolfswinkel, W F Seifert, J M van Re. Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211968. |
midbrain dopaminergic pathways and opioid receptor systems have been implicated in the reward experienced in electrical intracranial self-stimulation behavior. |
1989-02-23 |
2023-08-11 |
rat |
| L van Wolfswinkel, W F Seifert, J M van Re. Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211968. |
all doses of haloperidol and cocaine were administered with and without the opioid antagonist naloxone, in order to investigate the interaction between dopaminergic and opioid modulation of reward. |
1989-02-23 |
2023-08-11 |
rat |
| B Nurse, V A Russell, J J Taljaar. Characterization of the effects of serotonin on the release of [3H]dopamine from rat nucleus accumbens and striatal slices. Neurochemical research. vol 13. issue 5. 1988-09-22. PMID:3165497. |
the present results do not preclude the possibility that serotonin may affect the mesolimbic reward system at a site which is post-synaptic to dopaminergic terminals in the nucleus accumbens. |
1988-09-22 |
2023-08-11 |
rat |
| R A Wise, M A Bozart. Brain mechanisms of drug reward and euphoria. Psychiatric medicine. vol 3. issue 4. 1988-03-18. PMID:2893431. |
while both opiates and stimulants can activate (though by quite different mechanisms and at quite different loci) the dopaminergic circuitry underlying reward phenomena, only opiates activate the separate circuitry underlying dependence phenomena. |
1988-03-18 |
2023-08-11 |
Not clear |