| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P A Broderic. Rat striatal dopamine release mechanisms of cocaine. NIDA research monograph. vol 75. 1988-03-18. PMID:3123952. |
addictive drugs affect dopaminergic nigrostriatal and mesolimbic neuronal circuitry during brain reward. |
1988-03-18 |
2023-08-11 |
rat |
| P A Broderic. Rat striatal dopamine release mechanisms of cocaine. NIDA research monograph. vol 75. 1988-03-18. PMID:3123952. |
the results suggest that dopaminergic control over striatal neuronal membrane may be important in neurochemical mechanisms underlying brain reward. |
1988-03-18 |
2023-08-11 |
rat |
| K D Carr, T H Ba. Lateral hypothalamic stimulation-produced analgesia: inferred refractory period of directly stimulated neurons and resistance to pimozide antagonism. Physiology & behavior. vol 41. issue 4. 1988-03-15. PMID:3432389. |
thus, the dopaminergic second stage neurons deemed critical to feeding and reward may not play an important role in analgesia. |
1988-03-15 |
2023-08-11 |
Not clear |
| R A Wis. The role of reward pathways in the development of drug dependence. Pharmacology & therapeutics. vol 35. issue 1-2. 1988-02-20. PMID:3321101. |
benzodiazepines and barbiturates stimulate locomotor activity without stimulating dopamine turnover; they may interact with reward pathways at a synapse efferent to the dopaminergic link in the pathways. |
1988-02-20 |
2023-08-11 |
Not clear |
| H C Fibiger, F G LePiane, A Jakubovic, A G Phillip. The role of dopamine in intracranial self-stimulation of the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 12. 1988-01-28. PMID:3121802. |
the role of dopaminergic (da) neurons in brain stimulation reward produced by electrical stimulation of the ventral tegmental area (vta) was investigated in the rat. |
1988-01-28 |
2023-08-11 |
rat |
| H Nishino, Y Oomura, S Aou, L Lénár. Catecholaminergic mechanisms of feeding-related lateral hypothalamic activity in the monkey. Brain research. vol 405. issue 1. 1987-06-08. PMID:3567597. |
the data suggest that dopaminergic and noradrenergic inputs in the lha are crucial in task initiation and reward processing, respectively. |
1987-06-08 |
2023-08-11 |
monkey |
| J M Murphy, W J McBride, L Lumeng, T K L. Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacology, biochemistry, and behavior. vol 26. issue 2. 1987-06-02. PMID:2437596. |
this observation may indicate that p rats have a specific deficiency in the dopaminergic projections from the ventral tegmental area to the nucleus accumbens and, since the accumbens is an important structure in brain reward circuitry, it might also be an important determinant of the excessive volitional intake of alcohol by p rats. |
1987-06-02 |
2023-08-11 |
rat |
| A G Phillips, A Jakubovic, H C Fibige. Increased in vivo tyrosine hydroxylase activity in rat telencephalon produced by self-stimulation of the ventral tegmental area. Brain research. vol 402. issue 1. 1987-05-14. PMID:2881597. |
these results are consistent with a role for dopamine in brain-stimulation reward obtained from electrical stimulation of the ventral tegmental area but do not provide evidence for dopaminergic mediation of the rewarding properties of food. |
1987-05-14 |
2023-08-11 |
human |
| C R Cloninge. A unified biosocial theory of personality and its role in the development of anxiety states. Psychiatric developments. vol 4. issue 3. 1987-03-06. PMID:3809156. |
evidence suggests that variation in each dimension is strongly correlated with activity in a specific central monoaminergic pathway: novelty seeking with low basal dopaminergic activity, harm avoidance with high serotonergic activity, and reward dependence with low basal noradrenergic activity. |
1987-03-06 |
2023-08-11 |
Not clear |
| M A Bozart. Neural basis of psychomotor stimulant and opiate reward: evidence suggesting the involvement of a common dopaminergic system. Behavioural brain research. vol 22. issue 2. 1987-02-10. PMID:2878670. |
neural basis of psychomotor stimulant and opiate reward: evidence suggesting the involvement of a common dopaminergic system. |
1987-02-10 |
2023-08-11 |
Not clear |
| J R Blackburn, A G Phillips, A Jakubovic, H C Fibige. Increased dopamine metabolism in the nucleus accumbens and striatum following consumption of a nutritive meal but not a palatable non-nutritive saccharin solution. Pharmacology, biochemistry, and behavior. vol 25. issue 5. 1987-01-22. PMID:3786363. |
these results indicate that the type of food ingested can influence dopaminergic responses to feeding, and argue against an exclusive role for motor or reward processes in determining da activity. |
1987-01-22 |
2023-08-11 |
rat |
| E Miliaressis, J Malette, D Coulomb. The effects of pimozide on the reinforcing efficacy of central grey stimulation in the rat. Behavioural brain research. vol 21. issue 2. 1986-11-12. PMID:3755951. |
the fact that pimozide reduced the value of reward in an area containing only marginal amounts of dopaminergic cells adds support to the hypothesis that dopamine modulates reward indirectly. |
1986-11-12 |
2023-08-11 |
human |
| E Miliaressis, J Malette, D Coulomb. The effects of pimozide on the reinforcing efficacy of central grey stimulation in the rat. Behavioural brain research. vol 21. issue 2. 1986-11-12. PMID:3755951. |
the fact that the shift could not be increased with higher doses was interpreted as an indication that dopaminergic neurons are involved in a gate-like synaptic arrangement in which a limited decrease in dopaminergic activity is sufficient to obliterate the transmission in the reward pathway or the conversion of the signal into a reinforcing effect. |
1986-11-12 |
2023-08-11 |
human |
| A G Phillips, F G LePian. Effects of pimozide on positive and negative incentive contrast with rewarding brain stimulation. Pharmacology, biochemistry, and behavior. vol 24. issue 6. 1986-09-17. PMID:3737627. |
furthermore the effects of the dopamine receptor antagonist pimozide are consistent with a role for dopamine in brain-stimulation reward and also raise the possibility of dopaminergic involvement in incentive contrast phenomena. |
1986-09-17 |
2023-08-11 |
Not clear |
| B Nurse, V A Russell, J J Taljaar. Effect of chronic desipramine treatment on adrenoceptor modulation of [3H]dopamine release from rat nucleus accumbens slices. Brain research. vol 334. issue 2. 1985-07-24. PMID:3995319. |
this is consistent with behavioural evidence which suggests that the function of the mesolimbic dopaminergic reward system is facilitated by chronic treatment with antidepressant drugs. |
1985-07-24 |
2023-08-11 |
rat |
| C R Gallistel, Y Gomita, E Yadin, K A Campbel. Forebrain origins and terminations of the medial forebrain bundle metabolically activated by rewarding stimulation or by reward-blocking doses of pimozide. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 5. 1985-06-28. PMID:3873523. |
they also suggest that dopaminergic projection systems may not form part of the reward pathway itself. |
1985-06-28 |
2023-08-11 |
Not clear |
| L Van Wolfswinkel, J M Van Re. Hippocampus modulates self-stimulation reward from the ventral tegmental area in the rat. Brain research. vol 322. issue 1. 1985-03-07. PMID:6518367. |
it is suggested that the mesolimbic dopaminergic system is involved in this modulatory influence of the hippocampus on reward. |
1985-03-07 |
2023-08-12 |
rat |
| R A Wis. Neural mechanisms of the reinforcing action of cocaine. NIDA research monograph. vol 50. 1985-01-31. PMID:6440023. |
opiates also owe their reinforcing properties to their ability to activate dopaminergic synapses in brain reward circuitry, though they activate the system at a different site and by a different local mechanism than those of amphetamine and cocaine. |
1985-01-31 |
2023-08-12 |
human |
| M A Bozarth, R A Wis. Neural substrates of opiate reinforcement. Progress in neuro-psychopharmacology & biological psychiatry. vol 7. issue 4-6. 1984-03-08. PMID:6320300. |
at least one component of opiate reward is dependent on a dopaminergic system: (a) electrophysiological and neurochemical indices suggest that opiates activate ventral tegmental dopaminergic neurons, (b) ventral tegmental opiate infusions are behaviorally activating producing contralateral rotation that is blocked by neuroleptics, (c) reward from heroin is blocked by neuroleptics, and (d) reward from heroin is attenuated by dopamine-depleting lesions of the ventral tegmental system. |
1984-03-08 |
2023-08-12 |
rat |
| A G Phillips, F G LePiane, H C Fibige. Dopaminergic mediation of reward produced by direct injection of enkephalin into the ventral tegmental area of the rat. Life sciences. vol 33. issue 25. 1984-01-26. PMID:6417434. |
dopaminergic mediation of reward produced by direct injection of enkephalin into the ventral tegmental area of the rat. |
1984-01-26 |
2023-08-12 |
rat |