Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Michio Nomura, Ichiro Kusumi, Masayuki Kaneko, Takuya Masui, Makoto Daiguji, Takeji Ueno, Tsukasa Koyama, Yasuyuki Nomur. Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior. Psychopharmacology. vol 187. issue 1. 2007-07-09. PMID:16767413. |
impulsive behavior has been suggested to occur due to a dysfunction of serotonergic 5-ht neurotransmission. |
2007-07-09 |
2023-08-12 |
human |
Filip S van den Bergh, Emilie Bloemarts, Lucianne Groenink, Berend Olivier, Ronald S Oostin. Delay aversion: effects of 7-OH-DPAT, 5-HT1A/1B-receptor stimulation and D-cycloserine. Pharmacology, biochemistry, and behavior. vol 85. issue 4. 2007-05-09. PMID:17208285. |
the data suggest the dopamine d(3)-receptor and the 5-ht(1b)-receptor are interesting targets for treating delay aversion impulsivity. |
2007-05-09 |
2023-08-12 |
rat |
Marcin Wojnar, Kirk J Brower, Andrzej Jakubczyk, Izabela Zmigrodzka, Margit Burmeister, Halina Matsumoto, Elzbieta Woźny, Elzbieta Sliwerska, Andrea M Hegedus, Anna Husar, Anna Slufarska, Michał Lipiński, Robert A Zucke. [Influence of impulsivity, suicidality and serotonin genes on treatment outcomes in alcohol dependence]. Psychiatria polska. vol 40. issue 5. 2007-03-20. PMID:17217240. |
[influence of impulsivity, suicidality and serotonin genes on treatment outcomes in alcohol dependence]. |
2007-03-20 |
2023-08-12 |
Not clear |
Marcin Wojnar, Kirk J Brower, Andrzej Jakubczyk, Izabela Zmigrodzka, Margit Burmeister, Halina Matsumoto, Elzbieta Woźny, Elzbieta Sliwerska, Andrea M Hegedus, Anna Husar, Anna Slufarska, Michał Lipiński, Robert A Zucke. [Influence of impulsivity, suicidality and serotonin genes on treatment outcomes in alcohol dependence]. Psychiatria polska. vol 40. issue 5. 2007-03-20. PMID:17217240. |
the aim of the study was to identify risk factors of relapse by investigating relationships among suicidality, impulsivity, genetic markers of serotonin activity, and relapse in alcohol-dependent patients. |
2007-03-20 |
2023-08-12 |
Not clear |
Boris B Quednow, Kai-Uwe Kühn, Christian Hoppe, Jens Westheide, Wolfgang Maier, Irene Daum, Michael Wagne. Elevated impulsivity and impaired decision-making cognition in heavy users of MDMA ("Ecstasy"). Psychopharmacology. vol 189. issue 4. 2007-03-02. PMID:16425060. |
serotonin (5-ht) has been implicated in the regulation of impulsivity and such executive functions as decision-making cognition. |
2007-03-02 |
2023-08-12 |
human |
Stefano Pallanti, Silvia Bernardi, Leonardo Quercioli, Concetta DeCaria, Eric Hollande. Serotonin dysfunction in pathological gamblers: increased prolactin response to oral m-CPP versus placebo. CNS spectrums. vol 11. issue 12. 2007-02-28. PMID:17146409. |
acute administration of the partial serotonin (5-ht) agonist meta-chlorophenylpiperazine (m-cpp), that is used also as a street drug, has been reported to induce a "high" and craving response in various impulsive and substance addiction disorders. |
2007-02-28 |
2023-08-12 |
Not clear |
Jun Li, Yufeng Wang, Rulun Zhou, Haobo Zhang, Li Yang, Bing Wang, Stephen V Faraon. Association between polymorphisms in serotonin transporter gene and attention deficit hyperactivity disorder in Chinese Han subjects. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 1. 2007-02-27. PMID:16941663. |
prior work has shown reduced serotonin transmission to be associated with impulsivity and behavioral problems. |
2007-02-27 |
2023-08-12 |
human |
Ana Paula M Guimarães, Cristian Zeni, Guilherme V Polanczyk, Julia P Genro, Tatiana Roman, Luis A Rohde, Mara H Hut. Serotonin genes and attention deficit/hyperactivity disorder in a Brazilian sample: preferential transmission of the HTR2A 452His allele to affected boys. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 1. 2007-02-27. PMID:16958038. |
low serotonin activity has been associated in both animal and human studies with measures of impulsivity, aggression, and disinhibited behaviors, which make genes from the serotonin system reasonable candidates for adhd susceptibility. |
2007-02-27 |
2023-08-12 |
human |
Barbara J Bowers, Jill Miyamoto-Ditmon, Jeanne M Wehne. Regulation of 5-HT2A/C receptors and DOI-induced behaviors by protein kinase Cgamma. Pharmacology, biochemistry, and behavior. vol 85. issue 2. 2007-02-20. PMID:17109939. |
pharmacological studies have shown that 5-ht(2a/c) receptors modulate impulsivity and ethanol consumption in rodents and that pkc can regulate 5-ht(2a/c) receptors. |
2007-02-20 |
2023-08-12 |
mouse |
M Díaz-Marsa, C Lozano, A S Herranz, M J Asensio-Vegas, O Martín, L Revert, J Saiz-Ruiz, J L Carrasc. [Acute tryptophan depletion in eating disorders]. Actas espanolas de psiquiatria. vol 34. issue 6. 2007-02-20. PMID:17117337. |
furthermore, and given the relationship of the dysfunctions of serotonin activity with impulsive symptoms, the technique may be useful in biological differentiation of different subtypes, that is restrictive and bulimic, of ed. |
2007-02-20 |
2023-08-12 |
Not clear |
Joseph T Sakai, Susan E Young, Michael C Stallings, David Timberlake, Andrew Smolen, Gary L Stetler, Thomas J Crowle. Case-control and within-family tests for an association between conduct disorder and 5HTTLPR. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 141B. issue 8. 2007-02-13. PMID:16972235. |
several lines of research have suggested that serotonin dysfunction is associated with aggression, impulsivity, and antisocial behavior. |
2007-02-13 |
2023-08-12 |
Not clear |
Michio Nomura, Yasuyuki Nomur. Psychological, neuroimaging, and biochemical studies on functional association between impulsive behavior and the 5-HT2A receptor gene polymorphism in humans. Annals of the New York Academy of Sciences. vol 1086. 2007-02-13. PMID:17185512. |
it has been suggested that impulsive behavior is caused by dysfunctional serotonergic 5-ht neurotransmission in the central nervous system (cns). |
2007-02-13 |
2023-08-12 |
human |
Michio Nomura, Yasuyuki Nomur. Psychological, neuroimaging, and biochemical studies on functional association between impulsive behavior and the 5-HT2A receptor gene polymorphism in humans. Annals of the New York Academy of Sciences. vol 1086. 2007-02-13. PMID:17185512. |
positron emission tomography (pet) imaging with [(18)f]altanserin to characterize 5-ht(2a) receptor binding revealed a reduction in 5-ht(2a) binding in the ventral frontal cortex in women who had recovered from impulsive diseases. |
2007-02-13 |
2023-08-12 |
human |
Michio Nomura, Yasuyuki Nomur. Psychological, neuroimaging, and biochemical studies on functional association between impulsive behavior and the 5-HT2A receptor gene polymorphism in humans. Annals of the New York Academy of Sciences. vol 1086. 2007-02-13. PMID:17185512. |
these clinical, neuroimaging, and pharmacological studies appear to support the hypothesis that functional alteration of neurotransmission due to genetic polymorphisms of the 5-ht receptors may be involved in impulsive behavior modulation. |
2007-02-13 |
2023-08-12 |
human |
Michio Nomura, Yasuyuki Nomur. Psychological, neuroimaging, and biochemical studies on functional association between impulsive behavior and the 5-HT2A receptor gene polymorphism in humans. Annals of the New York Academy of Sciences. vol 1086. 2007-02-13. PMID:17185512. |
following evaluation by a self-reporting measure, it was proposed that a polymorphism in the promoter of the 5-ht(2a) receptor gene is the underlying cause of impulsive behavior; however, this hypothesis is not convincing. |
2007-02-13 |
2023-08-12 |
human |
Michio Nomura, Yasuyuki Nomur. Psychological, neuroimaging, and biochemical studies on functional association between impulsive behavior and the 5-HT2A receptor gene polymorphism in humans. Annals of the New York Academy of Sciences. vol 1086. 2007-02-13. PMID:17185512. |
we examined whether the polymorphism in the 5-ht(2a) receptor gene promoter is involved in impulsive aggression by evaluating a behavioral task (go/no-go task) in normal volunteers. |
2007-02-13 |
2023-08-12 |
human |
Charles S Carver, Christopher J Mille. Relations of serotonin function to personality: current views and a key methodological issue. Psychiatry research. vol 144. issue 1. 2007-02-12. PMID:16914207. |
review of evidence to date appears to link serotonin function to impulsivity and, to some extent, to hostility. |
2007-02-12 |
2023-08-12 |
Not clear |
Erik Ryding, Jan-Anders Ahnlide, Mats Lindström, Ingmar Rosén, Lil Träskman-Bend. Regional brain serotonin and dopamine transporter binding capacity in suicide attempters relate to impulsiveness and mental energy. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17085020. |
regional brain serotonin and dopamine transporter binding capacity in suicide attempters relate to impulsiveness and mental energy. |
2007-02-12 |
2023-08-12 |
human |
Daiki Masaki, Chihiro Yokoyama, Seijiro Kinoshita, Hideto Tsuchida, Yasuhito Nakatomi, Kanji Yoshimoto, Kenji Fuku. Relationship between limbic and cortical 5-HT neurotransmission and acquisition and reversal learning in a go/no-go task in rats. Psychopharmacology. vol 189. issue 2. 2007-02-05. PMID:17016708. |
central serotonin (5-ht) function has also been widely implicated in impulsivity; however, little research has addressed the regional aspect of 5-ht roles in different impulsive indices of task performance. |
2007-02-05 |
2023-08-12 |
rat |
Xingqun Ni, Ramprasad Bismil, Kirsten Chan, Tricia Sicard, Natalie Bulgin, Shelley McMain, James L Kenned. Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder. Neuroscience letters. vol 408. issue 3. 2007-01-23. PMID:17000047. |
the serotonin 2a receptor gene (htr2a) is considered a candidate gene for bpd because multiple lines of evidence suggest that it plays an important role in suicide, impulsivity and emotional liability. |
2007-01-23 |
2023-08-12 |
Not clear |