| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Gordon Frankle, Ilise Lombardo, Antonia S New, Marianne Goodman, Peter S Talbot, Yiyun Huang, Dah-Ren Hwang, Mark Slifstein, Susan Curry, Anissa Abi-Dargham, Marc Laruelle, Larry J Sieve. Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652. The American journal of psychiatry. vol 162. issue 5. 2005-06-08. PMID:15863793. |
this study evaluated regional serotonin transporter distribution in the brain of individuals with impulsive aggression by using positron emission tomography (pet) with the serotonin transporter pet radiotracer [(11)c]mcn 5652. |
2005-06-08 |
2023-08-12 |
human |
| Howard Steiger, Ridha Joober, Mimi Israël, Simon N Young, Ng Mien Kwong Ng Ying Kin, Lise Gauvin, Kenneth R Bruce, Jasmine Joncas, Adam Torkaman-Zeh. The 5HTTLPR polymorphism, psychopathologic symptoms, and platelet [3H-] paroxetine binding in bulimic syndromes. The International journal of eating disorders. vol 37. issue 1. 2005-05-24. PMID:15690467. |
a short (s) allele in the promoter region of the 5-hydroxytryptamine (5-ht) transporter gene (5httlpr) has been associated with low transcription of the 5-ht transporter protein, and with clinical manifestations including impulsivity, affective disorder, and bulimia nervosa. |
2005-05-24 |
2023-08-12 |
Not clear |
| Jun Li, Yufeng Wang, Rulun Zhou, Haobo Zhang, Li Yang, Bing Wang, Sajjad Khan, Stephen V Faraon. Serotonin 5-HT1B receptor gene and attention deficit hyperactivity disorder in Chinese Han subjects. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 132B. issue 1. 2005-05-12. PMID:15578608. |
serotonin is an endogenous neurotransmitter that regulates aggressive and impulsive behavior and may be involved in the development of attention deficit hyperactivity disorder (adhd). |
2005-05-12 |
2023-08-12 |
mouse |
| Marianne Goodman, Antonia New, Larry Sieve. Trauma, genes, and the neurobiology of personality disorders. Annals of the New York Academy of Sciences. vol 1032. 2005-04-19. PMID:15677398. |
for the dimension of impulsive aggression, often seen in borderline personality disorder (bpd), the underlying neurobiology involves deficits in central serotonin function and alterations in specific brain regions in the cingulate and the medial and orbital prefrontal cortex. |
2005-04-19 |
2023-08-12 |
monkey |
| Jennifer A Nasser, Marci E Gluck, Allan Geliebte. Impulsivity and test meal intake in obese binge eating women. Appetite. vol 43. issue 3. 2005-04-18. PMID:15527933. |
greater impulsivity has also been described in those with bulimia nervosa and attributed to aberrations in serotonin, as has eating in response to negative affect. |
2005-04-18 |
2023-08-12 |
Not clear |
| Antonia S New, Monte S Buchsbaum, Erin A Hazlett, Marianne Goodman, Harold W Koenigsberg, Jenni Lo, Lisa Iskander, Randall Newmark, Jesse Brand, Karen O'Flynn, Larry J Sieve. Fluoxetine increases relative metabolic rate in prefrontal cortex in impulsive aggression. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15160265. |
in addition, patients with impulsive aggression have an attenuation of symptoms with selective serotonin reuptake inhibitor (ssri) treatment. |
2005-03-01 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Jeffrey C Glennon, Trevor W Robbin. 5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15232674. |
5-ht2a and 5-ht2c receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-ht depletion. |
2005-03-01 |
2023-08-12 |
rat |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Jeffrey C Glennon, Trevor W Robbin. 5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15232674. |
in contrast, the 5-ht(2a) receptor antagonist m100907 decreases this measure of impulsivity. |
2005-03-01 |
2023-08-12 |
rat |
| C Reist, C Mazzanti, R Vu, K Fujimoto, D Goldma. Inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-HT2A candidate allele: His452Tyr. Molecular psychiatry. vol 9. issue 9. 2004-12-08. PMID:15037867. |
inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-ht2a candidate allele: his452tyr. |
2004-12-08 |
2023-08-12 |
human |
| C Reist, C Mazzanti, R Vu, K Fujimoto, D Goldma. Inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-HT2A candidate allele: His452Tyr. Molecular psychiatry. vol 9. issue 9. 2004-12-08. PMID:15037867. |
intracellular 5-ht-induced ca(2+) release by platelets and fenfluramine-induced prolactin release by pituitary were evaluated in 27 psychiatrically interviewed subjects (including both impulsive patients and controls) stratified by his452tyr genotype and also genotyped for a second 5-ht(2a) polymorphism, 102t>c. |
2004-12-08 |
2023-08-12 |
human |
| C Reist, C Mazzanti, R Vu, K Fujimoto, D Goldma. Inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-HT2A candidate allele: His452Tyr. Molecular psychiatry. vol 9. issue 9. 2004-12-08. PMID:15037867. |
subjects with increased measures of impulsivity showed decreased postreceptor 5-ht function, as indicated by reduced 5-ht-induced ca(2+) release, but no alteration in net 5-ht function, as measured by fenfluramine response. |
2004-12-08 |
2023-08-12 |
human |
| Jasminka Stefulj, Andreas Büttner, Josip Skavic, Peter Zill, Melita Balija, Wolfgang Eisenmenger, Brigitta Bondy, Branimir Jerne. Serotonin 1B (5HT-1B) receptor polymorphism (G861C) in suicide victims: association studies in German and Slavic population. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 127B. issue 1. 2004-11-02. PMID:15108179. |
serotonin 1b (5ht-1b) receptor mediates aggressive behavior in mice models and was proposed to be involved in the control of aggression and impulsivity in humans. |
2004-11-02 |
2023-08-12 |
mouse |
| Wolfgang Retz, Petra Retz-Junginger, Tillmann Supprian, Johannes Thome, Michael Rösle. Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathology. Behavioral sciences & the law. vol 22. issue 3. 2004-10-13. PMID:15211560. |
association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood adhd psychopathology. |
2004-10-13 |
2023-08-12 |
Not clear |
| Wolfgang Retz, Petra Retz-Junginger, Tillmann Supprian, Johannes Thome, Michael Rösle. Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathology. Behavioral sciences & the law. vol 22. issue 3. 2004-10-13. PMID:15211560. |
there is evidence that disturbances in central serotonin (5-ht) function have a role in impulsive aggression, violence, and criminality. |
2004-10-13 |
2023-08-12 |
Not clear |
| Enrique Baca-Garcia, Concepción Vaquero, Carmen Diaz-Sastre, Eloy García-Resa, Jeronimo Saiz-Ruiz, José Fernández-Piqueras, Jose de Leo. Lack of association between the serotonin transporter promoter gene polymorphism and impulsivity or aggressive behavior among suicide attempters and healthy volunteers. Psychiatry research. vol 126. issue 2. 2004-09-21. PMID:15123389. |
lack of association between the serotonin transporter promoter gene polymorphism and impulsivity or aggressive behavior among suicide attempters and healthy volunteers. |
2004-09-21 |
2023-08-12 |
human |
| Enrique Baca-Garcia, Concepción Vaquero, Carmen Diaz-Sastre, Eloy García-Resa, Jeronimo Saiz-Ruiz, José Fernández-Piqueras, Jose de Leo. Lack of association between the serotonin transporter promoter gene polymorphism and impulsivity or aggressive behavior among suicide attempters and healthy volunteers. Psychiatry research. vol 126. issue 2. 2004-09-21. PMID:15123389. |
the association between a polymorphism in the promoter area of the serotonin transporter (17q11.1-q12) with impulsivity and history of aggressive behavior was studied in a spanish general hospital. |
2004-09-21 |
2023-08-12 |
human |
| Mats B Lindström, Erik Ryding, Peter Bosson, Jan-Anders Ahnlide, Ingmar Rosén, Lil Träskman-Bend. Impulsivity related to brain serotonin transporter binding capacity in suicide attempters. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14. issue 4. 2004-09-07. PMID:15163439. |
impulsivity related to brain serotonin transporter binding capacity in suicide attempters. |
2004-09-07 |
2023-08-12 |
Not clear |
| Mats B Lindström, Erik Ryding, Peter Bosson, Jan-Anders Ahnlide, Ingmar Rosén, Lil Träskman-Bend. Impulsivity related to brain serotonin transporter binding capacity in suicide attempters. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14. issue 4. 2004-09-07. PMID:15163439. |
impulsiveness according to the marke nyman temperament (mnt) was significantly correlated to 5htt in suicide attempters, but not in controls. |
2004-09-07 |
2023-08-12 |
Not clear |
| Mats B Lindström, Erik Ryding, Peter Bosson, Jan-Anders Ahnlide, Ingmar Rosén, Lil Träskman-Bend. Impulsivity related to brain serotonin transporter binding capacity in suicide attempters. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14. issue 4. 2004-09-07. PMID:15163439. |
in suicide attempters, low 5htt was associated with impulsivity and to some extent with depressive disorder-key factors for suicidal behaviour. |
2004-09-07 |
2023-08-12 |
Not clear |
| Howard Steiger, Lise Gauvin, Mimi Israël, N M K Ng Ying Kin, Simon N Young, Julie Roussi. Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders. The Journal of clinical psychiatry. vol 65. issue 6. 2004-08-31. PMID:15291661. |
across populations, findings associate impulsivity, behavioral disinhibition, or hostility with reduced central serotonin (5-hydroxytryptamine: 5-ht) activity and increased likelihood of childhood abuse. |
2004-08-31 |
2023-08-12 |
Not clear |