| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael J Minzenberg, Robert Grossman, Antonia S New, Vivian Mitropoulou, Rachel Yehuda, Marianne Goodman, Diedre A Reynolds, Jeremy M Silverman, Emil F Coccaro, Sue Marcus, Larry J Sieve. Blunted hormone responses to Ipsapirone are associated with trait impulsivity in personality disorder patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 1. 2006-05-12. PMID:16123761. |
in addition, d(2) receptor dysfunction may play a role in impulsivity, whereas 5-ht(1a) cell-body autoreceptor function may be spared in these disorders. |
2006-05-12 |
2023-08-12 |
human |
| Cindy K J Lieben, Harry W M Steinbusch, Arjan Bloklan. 5,7-DHT lesion of the dorsal raphe nuclei impairs object recognition but not affective behavior and corticosterone response to stressor in the rat. Behavioural brain research. vol 168. issue 2. 2006-05-09. PMID:16360222. |
the substantial reduction in neuronal 5-ht markers in the dorsal raphe did not affect anxiety-related, depressive-like or impulsive behavior. |
2006-05-09 |
2023-08-12 |
rat |
| John C Talpos, Lawrence S Wilkinson, Trevor W Robbin. A comparison of multiple 5-HT receptors in two tasks measuring impulsivity. Journal of psychopharmacology (Oxford, England). vol 20. issue 1. 2006-03-29. PMID:16204332. |
a comparison of multiple 5-ht receptors in two tasks measuring impulsivity. |
2006-03-29 |
2023-08-12 |
Not clear |
| John C Talpos, Lawrence S Wilkinson, Trevor W Robbin. A comparison of multiple 5-HT receptors in two tasks measuring impulsivity. Journal of psychopharmacology (Oxford, England). vol 20. issue 1. 2006-03-29. PMID:16204332. |
to test this hypothesis, behavioural effects of three partially selective serotonergic (5-ht) ligands, ketanserin (5-ht2(a, c) receptor antagonist), ser-082 (5-ht2(c, b) receptor antagonist) and sb-270146-a (5-ht6 receptor antagonist) were compared in two tests of impulsivity. |
2006-03-29 |
2023-08-12 |
Not clear |
| Trevor W Robbin. Chemistry of the mind: neurochemical modulation of prefrontal cortical function. The Journal of comparative neurology. vol 493. issue 1. 2006-03-09. PMID:16254988. |
evidence is surveyed from studies of rats, nonhuman primates, and humans to suggest that prefrontal dopamine has specific functions in attentional control and working memory, mediated mainly through the d1 receptor, whereas manipulations of serotonin are shown by contrast to affect reversal learning in monkeys and human volunteers and measures of impulsivity in rats. |
2006-03-09 |
2023-08-12 |
human |
| M Wohl, D Purper-Ouakil, M C Mouren, J Adès, P Gorwoo. [Meta-analysis of candidate genes in attention-deficit hyperactivity disorder]. L'Encephale. vol 31. issue 4 Pt 1. 2006-02-24. PMID:16389711. |
genes involved in dopamine, serotonin, and noradrenalin systems have thus been assessed for their role in core features of adhd, such as motor overactivity, inattention, and impulsiveness. |
2006-02-24 |
2023-08-12 |
Not clear |
| L Clark, J P Roiser, R Cools, D C Rubinsztein, B J Sahakian, T W Robbin. Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity. Psychopharmacology. vol 182. issue 4. 2006-02-14. PMID:16163530. |
stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-ht theory of impulsivity. |
2006-02-14 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Rudolf N Cardinal, Trevor W Robbin. Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice. Cerebral cortex (New York, N.Y. : 1991). vol 16. issue 1. 2006-01-20. PMID:15829733. |
in the current experiment, levels of dopamine, serotonin and their metabolites were measured in the medial pfc (n = 12) and orbitofrontal cortex (ofc) (n = 19) of rats using in vivo microdialysis during the delay-discounting model of impulsive choice, where impulsivity is defined as selection of small immediate over larger delayed rewards. |
2006-01-20 |
2023-08-12 |
human |
| N Bradley Keel. The role of serotonin in impulsive and aggressive behaviors associated with epilepsy-like neuronal hyperexcitability in the amygdala. Epilepsy & behavior : E&B. vol 7. issue 3. 2005-12-20. PMID:16103019. |
the role of serotonin in impulsive and aggressive behaviors associated with epilepsy-like neuronal hyperexcitability in the amygdala. |
2005-12-20 |
2023-08-12 |
Not clear |
| Stephen J Suom. Aggression and social behaviour in rhesus monkeys. Novartis Foundation symposium. vol 268. 2005-10-27. PMID:16206883. |
for example, approximately 5-10% of rhesus monkeys growing up in the wild consistently exhibit impulsive and/or inappropriately aggressive responses to mildly stressful situations throughout development; those same individuals also show chronic deficits in their central serotonin metabolism. |
2005-10-27 |
2023-08-12 |
human |
| Anthony R Isles, Gareth J Hathway, Trevor Humby, Carlos de la Riva, Keith M Kendrick, Lawrence S Wilkinso. An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task. The European journal of neuroscience. vol 22. issue 4. 2005-10-18. PMID:16115223. |
one psychology in which 5-ht plays an important role is impulsive responding. |
2005-10-18 |
2023-08-12 |
Not clear |
| Anthony R Isles, Gareth J Hathway, Trevor Humby, Carlos de la Riva, Keith M Kendrick, Lawrence S Wilkinso. An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task. The European journal of neuroscience. vol 22. issue 4. 2005-10-18. PMID:16115223. |
here, we examined the neurobiological relevance of a recently discovered single nucleotide polymorphism (snp) in the murine gene tryptophan hydroxylase (mtph2) by analysing extracellular levels of 5-ht in medial prefrontal cortex (mpfc) and ventral striatum (vs), key brain regions for impulsive behaviours. |
2005-10-18 |
2023-08-12 |
Not clear |
| Anthony R Isles, Gareth J Hathway, Trevor Humby, Carlos de la Riva, Keith M Kendrick, Lawrence S Wilkinso. An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task. The European journal of neuroscience. vol 22. issue 4. 2005-10-18. PMID:16115223. |
the allelic variants were associated with systematic effects on baseline 5-ht efflux in the mpfc and vs. we then went on to examine whether the mtph2 allelic variants gave rise to differences in impulsive behaviour. |
2005-10-18 |
2023-08-12 |
Not clear |
| Katya Rubia, Francis Lee, Anthony J Cleare, Nigel Tunstall, Cynthia H Y Fu, Michael Brammer, Phillip McGuir. Tryptophan depletion reduces right inferior prefrontal activation during response inhibition in fast, event-related fMRI. Psychopharmacology. vol 179. issue 4. 2005-09-15. PMID:15887056. |
in animal and human studies, the neurotransmitter serotonin (5-hydroxytryptamine; 5-ht) has been implicated in mediating impulsiveness and aggression. |
2005-09-15 |
2023-08-12 |
human |
| Enrique Baca-García, Beatríz Rodríguez Salgado, Helen Dolengevich Segal, Concepción Vaquero Lorenzo, Mercedes Navio Acosta, Manuel Arrojo Romero, Montserrat Díaz Hernández, Jeronimo Saiz-Ruiz, Jose Fernandez Piqueras, Jose de Leo. A pilot genetic study of the continuum between compulsivity and impulsivity in females: the serotonin transporter promoter polymorphism. Progress in neuro-psychopharmacology & biological psychiatry. vol 29. issue 5. 2005-08-26. PMID:15908092. |
a pilot genetic study of the continuum between compulsivity and impulsivity in females: the serotonin transporter promoter polymorphism. |
2005-08-26 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Trevor W Robbin. Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 4. 2005-07-28. PMID:15688093. |
forebrain serotonergic lesions attenuate the ability of d-amphetamine to decrease impulsivity in a delay-discounting paradigm, potentially through interactions between the serotonin (5-ht) and dopamine (da) systems. |
2005-07-28 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Trevor W Robbin. Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 4. 2005-07-28. PMID:15688093. |
in the current study, the effects of intra-accumbal infusions of 6-hydroxydopamine (6-ohda) on impulsive choice were evaluated, in combination with d-amphetamine and serotonergic drugs, in order to investigate the importance of 5-ht : da interactions in the control of impulsive behavior. |
2005-07-28 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Trevor W Robbin. Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 4. 2005-07-28. PMID:15688093. |
8-oh-dpat (1.0 mg/kg) increased impulsivity in sham-operated controls, an effect which was blocked by the 5-ht(1a) receptor antagonist way 100635. |
2005-07-28 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Trevor W Robbin. Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 4. 2005-07-28. PMID:15688093. |
these data suggest a significant role for 5-ht : da interactions within the nac in the control of impulsivity, and in the mechanism by which amphetamine decreases impulsive choice. |
2005-07-28 |
2023-08-12 |
human |
| W Gordon Frankle, Ilise Lombardo, Antonia S New, Marianne Goodman, Peter S Talbot, Yiyun Huang, Dah-Ren Hwang, Mark Slifstein, Susan Curry, Anissa Abi-Dargham, Marc Laruelle, Larry J Sieve. Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652. The American journal of psychiatry. vol 162. issue 5. 2005-06-08. PMID:15863793. |
brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11c]mcn 5652. |
2005-06-08 |
2023-08-12 |
human |