| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kathryn S Saadat, J Martin Elliott, A Richard Green, Paula M Mora. High-dose MDMA does not result in long-term changes in impulsivity in the rat. Psychopharmacology. vol 188. issue 1. 2006-12-22. PMID:16896956. |
evidence suggests that recreational users of (+/-)3,4-methylenedioxymethamphetamine hcl (mdma, "ecstasy") have cognitive and behavioral deficits and show increased impulsivity consistent with 5-hydroxytryptamine (5-ht) neurotoxicity. |
2006-12-22 |
2023-08-12 |
rat |
| Xingqun Ni, Kirsten Chan, Natalie Bulgin, Tricia Sicard, Ramprasad Bismil, Shelley McMain, James L Kenned. Association between serotonin transporter gene and borderline personality disorder. Journal of psychiatric research. vol 40. issue 5. 2006-11-14. PMID:16690085. |
the serotonin transporter gene (5-htt) is considered as a candidate gene for bpd as multiple lines of evidence have suggested that it plays an important role in suicide, impulsive behaviour, and emotional liability. |
2006-11-14 |
2023-08-12 |
Not clear |
| Alja Videtic, Galina Pungercic, Irena Zupanic Pajnic, Tomaz Zupanc, Joze Balazic, Martina Tomori, Radovan Kome. Association study of seven polymorphisms in four serotonin receptor genes on suicide victims. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 141B. issue 6. 2006-10-18. PMID:16856120. |
a number of molecular genetic studies have investigated if serotonin (5-ht) receptor subtypes are involved in the pathogenesis of depression, suicidal behavior, aggression, and impulsive behavior. |
2006-10-18 |
2023-08-12 |
human |
| Linda Booij, Cees A Swenne, Jos F Brosschot, P M Judith Haffmans, Julian F Thayer, A J Willem Van der Doe. Tryptophan depletion affects heart rate variability and impulsivity in remitted depressed patients with a history of suicidal ideation. Biological psychiatry. vol 60. issue 5. 2006-10-12. PMID:16603135. |
the present study investigated whether experimental lowering of serotonin would decrease heart rate variability and increase impulsivity in remitted depressed patients, in particular in those patients with disturbed impulse control. |
2006-10-12 |
2023-08-12 |
Not clear |
| Ghazal Zaboli, Rinat Gizatullin, Asa Nilsonne, Alexander Wilczek, Erik G Jönsson, Ewa Ahnemark, Marie Asberg, Rosario Leopard. Tryptophan hydroxylase-1 gene variants associate with a group of suicidal borderline women. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 9. 2006-09-28. PMID:16495936. |
alterations in the serotonin (5-ht) system have been related to impulsive aggression and suicidal behavior, common features of the borderline personality disorder (bpd). |
2006-09-28 |
2023-08-12 |
Not clear |
| Eszter Kirilly, Anita Benko, Linda Ferrington, Romeo D Ando, Paul A T Kelly, Gyorgy Bagd. Acute and long-term effects of a single dose of MDMA on aggression in Dark Agouti rats. The international journal of neuropsychopharmacology. vol 9. issue 1. 2006-09-19. PMID:16060968. |
mdma causes selective depletion of serotonergic terminals in experimental animals and the consequent decrease in synaptic 5-ht may, inter alia, increase impulsivity. |
2006-09-19 |
2023-08-12 |
rat |
| Jana Wrase, Matthias Reimold, Imke Puls, Thorsten Kienast, Andreas Hein. Serotonergic dysfunction: brain imaging and behavioral correlates. Cognitive, affective & behavioral neuroscience. vol 6. issue 1. 2006-09-19. PMID:16869229. |
a low serotonin turnover rate and a high availability of serotonin transporters were associated with reduced response to excessive alcohol intake, anxiety, and impulsive aggression. |
2006-09-19 |
2023-08-12 |
Not clear |
| Erin L Kinnally, Heather A Jensen, Jennifer H Ewing, Jeffrey A Frenc. Serotonin function is associated with behavioral response to a novel conspecific in marmosets. American journal of primatology. vol 68. issue 8. 2006-09-18. PMID:16847970. |
the function of the central nervous system neurotransmitter serotonin (5-ht) contributes to individual differences in impulsive behavior in humans and nonhuman primates. |
2006-09-18 |
2023-08-12 |
marmoset |
| Michael John Morgan, Lara Chiara Impallomeni, Alessandro Pirona, Robert David Roger. Elevated impulsivity and impaired decision-making in abstinent Ecstasy (MDMA) users compared to polydrug and drug-naïve controls. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 7. 2006-09-05. PMID:16292322. |
serotonin is believed to mediate impulsive behavior and effective decision-making. |
2006-09-05 |
2023-08-12 |
human |
| Kathrin Ritter, C H Lammer. [Nacissistic personality disorder]. MMW Fortschritte der Medizin. vol 148. issue 8. 2006-06-21. PMID:16566103. |
impulsive and aggressive behavior and attacks of depression may be reduced through the use of selective serotonin reuptake inhibitors. |
2006-06-21 |
2023-08-12 |
Not clear |
| Kenneth R Bruce, Howard Steiger, Ridha Joober, N M K Ng Ying Kin, Mimi Israel, Simon N Youn. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 137B. issue 1. 2006-05-30. PMID:15999344. |
association of the promoter polymorphism -1438g/a of the 5-ht2a receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. |
2006-05-30 |
2023-08-12 |
human |
| Kenneth R Bruce, Howard Steiger, Ridha Joober, N M K Ng Ying Kin, Mimi Israel, Simon N Youn. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 137B. issue 1. 2006-05-30. PMID:15999344. |
separate lines of research suggest that the functional alterations in the serotonin (5-ht) 2a receptor are associated with 5-ht tone, behavioral impulsiveness, and bulimia nervosa (bn). |
2006-05-30 |
2023-08-12 |
human |
| Kenneth R Bruce, Howard Steiger, Ridha Joober, N M K Ng Ying Kin, Mimi Israel, Simon N Youn. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 137B. issue 1. 2006-05-30. PMID:15999344. |
we explored the effect of allelic variations within the 5-ht2a receptor gene promoter polymorphism -1438g/a on trait impulsiveness and serotonin function in women with bn. |
2006-05-30 |
2023-08-12 |
human |
| Kenneth R Bruce, Howard Steiger, Ridha Joober, N M K Ng Ying Kin, Mimi Israel, Simon N Youn. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 137B. issue 1. 2006-05-30. PMID:15999344. |
findings indicate that women with bn who are gg homozygotes on the -1438g/a promoter polymorphism are characterized by increased impulsiveness and lower sensitivity to post-synaptic serotonin activation. |
2006-05-30 |
2023-08-12 |
human |
| Kenneth R Bruce, Howard Steiger, Ridha Joober, N M K Ng Ying Kin, Mimi Israel, Simon N Youn. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 137B. issue 1. 2006-05-30. PMID:15999344. |
these findings implicate the gg genotype in the co-aggregation of impulsive behaviors and alterations of post-synaptic 5-ht functioning in women with bn. |
2006-05-30 |
2023-08-12 |
human |
| Alyson J Bon. Antidepressant treatments and human aggression. European journal of pharmacology. vol 526. issue 1-3. 2006-05-25. PMID:16253231. |
serotonin has been specifically associated with impulse regulation and deficiencies in serotonin have been linked to impulsive aggression. |
2006-05-25 |
2023-08-12 |
human |
| Pier Francesco Ferrari, Paola Palanza, Stefano Parmigiani, Rosa M M de Almeida, Klaus A Micze. Serotonin and aggressive behavior in rodents and nonhuman primates: predispositions and plasticity. European journal of pharmacology. vol 526. issue 1-3. 2006-05-25. PMID:16289029. |
studies in primates suggest that deficit in serotonin activity, as indicated by the levels of the cerebrospinal fluid (csf) serotonin major metabolite 5-hydroxyindoleacetic acid (5-hiaa) correlates with impulsive and aggressive behavior. |
2006-05-25 |
2023-08-12 |
Not clear |
| Yoram Barak, Ahikam Olmer, Dov Aizenber. Antidepressants reduce the risk of suicide among elderly depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 1. 2006-05-12. PMID:16123751. |
treatment with selective serotonin reuptake inhibitors (ssris) may increase the risk of impulsive acts including suicide, while data from epidemiological studies suggest that the effect of ssris in the elderly may be beneficial. |
2006-05-12 |
2023-08-12 |
Not clear |
| Michael J Minzenberg, Robert Grossman, Antonia S New, Vivian Mitropoulou, Rachel Yehuda, Marianne Goodman, Diedre A Reynolds, Jeremy M Silverman, Emil F Coccaro, Sue Marcus, Larry J Sieve. Blunted hormone responses to Ipsapirone are associated with trait impulsivity in personality disorder patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 1. 2006-05-12. PMID:16123761. |
we tested the hypothesis that central 5-ht(1a) receptor function is impaired in impulsive aggressive personality disorder patients. |
2006-05-12 |
2023-08-12 |
human |
| Michael J Minzenberg, Robert Grossman, Antonia S New, Vivian Mitropoulou, Rachel Yehuda, Marianne Goodman, Diedre A Reynolds, Jeremy M Silverman, Emil F Coccaro, Sue Marcus, Larry J Sieve. Blunted hormone responses to Ipsapirone are associated with trait impulsivity in personality disorder patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 1. 2006-05-12. PMID:16123761. |
impulsivity is related to impaired function at (or downstream to) postsynaptic 5-ht(1a) receptors, and this relationship may be partly responsible for the association of impaired serotonergic function with diagnoses such as bpd and ied-r. |
2006-05-12 |
2023-08-12 |
human |