| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji Liu, Kristie Conde, Peng Zhang, Varoth Lilascharoen, Zihui Xu, Byung Kook Lim, Randy J Seeley, J Julius Zhu, Michael M Scott, Zhiping P Pan. Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus. Neuron. vol 96. issue 4. 2017-12-22. PMID:29056294. |
glucagon-like peptide 1 (glp-1)-expressing neurons in the hindbrain send robust projections to the paraventricular nucleus of the hypothalamus (pvn), which is involved in the regulation of food intake. |
2017-12-22 |
2023-08-13 |
Not clear |
| Bin Li, Qian-Xing Zhuang, He-Ren Gao, Jian-Jun Wang, Jing-Ning Zh. Medial cerebellar nucleus projects to feeding-related neurons in the ventromedial hypothalamic nucleus in rats. Brain structure & function. vol 222. issue 2. 2017-10-20. PMID:27342113. |
the cerebellum, a hindbrain motor center, also participates in regulating nonsomatic visceral activities such as feeding control. |
2017-10-20 |
2023-08-13 |
rat |
| Linda Yang, Chih-Chuan Chang, Zhe Sun, Dennis Madsen, Haisun Zhu, Søren B Padkjær, Xiaoai Wu, Tao Huang, Karin Hultman, Sarah J Paulsen, Jishu Wang, Anne Bugge, Jane Boesen Frantzen, Per Nørgaard, Jacob Fuglsbjerg Jeppesen, Zhiru Yang, Anna Secher, Haibin Chen, Xun Li, Linu Mary John, Bing Shan, Zhenhua He, Xiang Gao, Jing Su, Kristian T Hansen, Wei Yang, Sebastian Beck Jørgense. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nature medicine. vol 23. issue 10. 2017-10-16. PMID:28846099. |
we further found that gfral expression was limited to hindbrain neurons and not present in peripheral tissues, which suggests that gdf15-gfral-mediated regulation of food intake is by a central mechanism. |
2017-10-16 |
2023-08-13 |
mouse |
| Zhi Yi Ong, Diana M Bongiorno, Mary Ann Hernando, Harvey J Gril. Effects of Endogenous Oxytocin Receptor Signaling in Nucleus Tractus Solitarius on Satiation-Mediated Feeding and Thermogenic Control in Male Rats. Endocrinology. vol 158. issue 9. 2017-10-02. PMID:28575174. |
unexplored were the energetic effects of hindbrain ot-r agonism and the physiological relevance of nts ot-r signaling on food intake and energy expenditure control. |
2017-10-02 |
2023-08-13 |
rat |
| Fredrik Anesten, Marie K Holt, Erik Schéle, Vilborg Pálsdóttir, Frank Reimann, Fiona M Gribble, Cecilia Safari, Karolina P Skibicka, Stefan Trapp, John-Olov Jansso. Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to IL-6. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 1. 2017-07-24. PMID:27097661. |
neuronal circuits in the hypothalamus and hindbrain are of importance for control of food intake, energy expenditure, and fat mass. |
2017-07-24 |
2023-08-13 |
mouse |
| Fredrik Anesten, Marie K Holt, Erik Schéle, Vilborg Pálsdóttir, Frank Reimann, Fiona M Gribble, Cecilia Safari, Karolina P Skibicka, Stefan Trapp, John-Olov Jansso. Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to IL-6. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 1. 2017-07-24. PMID:27097661. |
we have recently shown that treatment with exendin-4 (ex-4), an analog of the proglucagon-derived molecule glucagon-like peptide 1 (glp-1), markedly increases mrna expression of the cytokine interleukin-6 (il-6) in the hypothalamus and hindbrain and that this increase partly mediates the suppression of food intake and body weight by ex-4. |
2017-07-24 |
2023-08-13 |
mouse |
| Patrick Sweeney, Yunlei Yan. An Inhibitory Septum to Lateral Hypothalamus Circuit That Suppresses Feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 44. 2017-07-19. PMID:27807162. |
feeding behavior is orchestrated by neural circuits primarily residing in the hypothalamus and hindbrain. |
2017-07-19 |
2023-08-13 |
mouse |
| Patrick Sweeney, Yunlei Yan. An Inhibitory Septum to Lateral Hypothalamus Circuit That Suppresses Feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 44. 2017-07-19. PMID:27807162. |
however, the relative influence of cognitive and emotional brain circuits to the feeding circuitry in the hypothalamus and hindbrain remains unclear. |
2017-07-19 |
2023-08-13 |
mouse |
| Elizabeth G Mietlicki-Baase, Lauren E McGrath, Kieran Koch-Laskowski, Joanna Krawczyk, Tram Pham, Rinzin Lhamo, David J Reiner, Matthew R Haye. Hindbrain DPP-IV inhibition improves glycemic control and promotes negative energy balance. Physiology & behavior. vol 173. 2017-06-30. PMID:28119159. |
to test whether hindbrain dpp-iv inhibition suppresses blood glucose, feeding, and body weight gain, the effects of 4th intracerebroventricular (icv) administration of the fda-approved dpp-iv inhibitor sitagliptin were evaluated. |
2017-06-30 |
2023-08-13 |
Not clear |
| Scott E Kanoski, Matthew R Hayes, Karolina P Skibick. GLP-1 and weight loss: unraveling the diverse neural circuitry. American journal of physiology. Regulatory, integrative and comparative physiology. vol 310. issue 10. 2017-06-27. PMID:27030669. |
particular attention is devoted to discussion regarding the numerous neural substrates through which glp-1 and glp-1 analogs act to reduce food intake and body weight, including various hypothalamic nuclei (arcuate nucleus of the hypothalamus, periventricular hypothalamus, lateral hypothalamic area), hindbrain nuclei (parabrachial nucleus, medial nucleus tractus solitarius), hippocampus (ventral subregion; vhp), and nuclei embedded within the mesolimbic reward circuitry [ventral tegmental area (vta) and nucleus accumbens (nac)]. |
2017-06-27 |
2023-08-13 |
Not clear |
| Richard C Rogers, Sue Ritter, Gerlinda E Herman. Hindbrain cytoglucopenia-induced increases in systemic blood glucose levels by 2-deoxyglucose depend on intact astrocytes and adenosine release. American journal of physiology. Regulatory, integrative and comparative physiology. vol 310. issue 11. 2017-06-26. PMID:27101298. |
this counter-regulatory response (crr) is evoked by local hindbrain cytoglucopenia that causes an autonomically mediated increase in blood glucose, feeding behavior, and accelerated digestion; that is, actions that restore glucose homeostasis. |
2017-06-26 |
2023-08-13 |
rat |
| Miguel López, Rubén Nogueiras, Manuel Tena-Sempere, Carlos Diégue. Hypothalamic AMPK: a canonical regulator of whole-body energy balance. Nature reviews. Endocrinology. vol 12. issue 7. 2017-06-26. PMID:27199291. |
current evidence has implicated ampk in the hypothalamus and hindbrain with feeding, brown adipose tissue thermogenesis and browning of white adipose tissue, through modulation of the sympathetic nervous system, as well as glucose homeostasis. |
2017-06-26 |
2023-08-13 |
Not clear |
| F S H Alenazi, B A Ibrahim, H Al-Hamami, M Shakiya, K P Brisk. Role of estradiol in intrinsic hindbrain AMPK regulation of hypothalamic AMPK, metabolic neuropeptide, and norepinephrine activity and food intake in the female rat. Neuroscience. vol 314. 2016-10-13. PMID:26628404. |
role of estradiol in intrinsic hindbrain ampk regulation of hypothalamic ampk, metabolic neuropeptide, and norepinephrine activity and food intake in the female rat. |
2016-10-13 |
2023-08-13 |
rat |
| F S H Alenazi, B A Ibrahim, H Al-Hamami, M Shakiya, K P Brisk. Role of estradiol in intrinsic hindbrain AMPK regulation of hypothalamic AMPK, metabolic neuropeptide, and norepinephrine activity and food intake in the female rat. Neuroscience. vol 314. 2016-10-13. PMID:26628404. |
this study addressed the hypothesis that dorsomedial hindbrain adenosine 5'-monophosphate-activated protein kinase (ampk) imposes inherent estradiol-dependent control of hypothalamic ampk, neuropeptide, and norepinephrine (ne) activity and feeding in the female rat. |
2016-10-13 |
2023-08-13 |
rat |
| F S H Alenazi, B A Ibrahim, H Al-Hamami, M Shakiya, K P Brisk. Role of estradiol in intrinsic hindbrain AMPK regulation of hypothalamic AMPK, metabolic neuropeptide, and norepinephrine activity and food intake in the female rat. Neuroscience. vol 314. 2016-10-13. PMID:26628404. |
results implicate dorsomedial hindbrain ampk in physiological stimulus-induced feeding in females. |
2016-10-13 |
2023-08-13 |
rat |
| Bart C De Jonghe, Ruby A Holland, Diana R Olivos, Laura E Rupprecht, Scott E Kanoski, Matthew R Haye. Hindbrain GLP-1 receptor mediation of cisplatin-induced anorexia and nausea. Physiology & behavior. vol 153. 2016-09-30. PMID:26522737. |
as the hindbrain glucagon-like peptide-1 (glp-1) system contributes to energy balance and mediates aversive and stressful stimuli, here we examine the hypothesis that hindbrain glp-1 signaling mediates aspects of chemotherapy-induced nausea and reductions in feeding behavior in rats. |
2016-09-30 |
2023-08-13 |
rat |
| Patrick Sweeney, Yunlei Yan. An excitatory ventral hippocampus to lateral septum circuit that suppresses feeding. Nature communications. vol 6. 2016-05-31. PMID:26666960. |
previous research has focused on feeding circuits residing in the hindbrain and midbrain that govern homeostatic or hedonic control of food intake. |
2016-05-31 |
2023-08-13 |
Not clear |
| Ulrika Smedh, Karen A Scott, Timothy H Mora. Fourth ventricular CART peptide induces c-fos in the area postrema and nucleus of the solitary tract via a CRF-receptor dependent mechanism. Neuroscience letters. vol 609. 2016-04-15. PMID:26475505. |
whereas, the cartp inhibition of gastric emptying was blocked by pre-treatment with a non-selective corticotropin releasing factor (crf) antagonist, sucrose drinking was not, suggesting that cartp- and crf controls for food intake and gastric emptying are operated through separable dorsal hindbrain mechanisms. |
2016-04-15 |
2023-08-13 |
rat |
| Jennifer C Swick, Amber L Alhadeff, Harvey J Grill, Paula Urrea, Stephanie M Lee, Hyunsun Roh, John-Paul Bair. Parabrachial Nucleus Contributions to Glucagon-Like Peptide-1 Receptor Agonist-Induced Hypophagia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 8. 2016-03-08. PMID:25703200. |
we evaluated the contributions of the hindbrain parabrachial nucleus (pbn) to systemic ex4-induced hypophagia, as the pbn receives gustatory and visceral afferent relays and descending input from several brain nuclei associated with feeding. |
2016-03-08 |
2023-08-13 |
human |
| Jennifer E Richard, Rozita H Anderberg, Andreas Göteson, Fiona M Gribble, Frank Reimann, Karolina P Skibick. Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system. PloS one. vol 10. issue 3. 2016-02-09. PMID:25793511. |
the gut/brain peptide, glucagon like peptide 1 (glp-1), suppresses food intake by acting on receptors located in key energy balance regulating cns areas, the hypothalamus or the hindbrain. |
2016-02-09 |
2023-08-13 |
rat |