| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Siew Cheng Phua, Yu Lin Tan, Alison Maun Yeng Kok, Esra Senol, Christine Jin Hui Chiam, Chun-Yao Lee, Yanmin Peng, Auriel Theodora Jacobea Lim, Hasan Mohammad, Jing-Xuan Lim, Yu F. A distinct parabrachial-to-lateral hypothalamus circuit for motivational suppression of feeding by nociception. Science advances. vol 7. issue 19. 2021-06-25. PMID:33962958. |
how the mouse hypothalamus, the feeding regulation center, integrates nociceptive inputs to modulate feeding is unclear. |
2021-06-25 |
2023-08-13 |
mouse |
| L L Koekkoek, U A Unmehopa, L Eggels, T Kool, K Lamuadni, C Diepenbroek, J D Mul, M J Serlie, S E la Fleu. A free-choice high-fat diet modulates the effects of a sucrose bolus on the expression of genes involved in glucose handling in the hypothalamus and nucleus accumbens. Physiology & behavior. vol 222. 2021-06-21. PMID:32417644. |
in this study we hypothesize that saturated fat intake modulates glucose handling in the hypothalamus and nucleus accumbens, both brain areas highly involved in the control of food intake. |
2021-06-21 |
2023-08-13 |
rat |
| Antonio J López-Gambero, Cristina Rosell-Valle, Dina Medina-Vera, Juan Antonio Navarro, Antonio Vargas, Patricia Rivera, Carlos Sanjuan, Fernando Rodríguez de Fonseca, Juan Suáre. A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer's Disease, the 5XFAD Mouse. International journal of molecular sciences. vol 22. issue 10. 2021-06-17. PMID:34065168. |
here, a humanized ad model, the 5xfad mouse model, was used to further explore food intake, energy expenditure, neuroinflammation, and neuroendocrine signaling in the hypothalamus. |
2021-06-17 |
2023-08-13 |
mouse |
| Beatriz Ferrer, Lisa M Prince, Alexey A Tinkov, Abel Santamaria, Marcelo Farina, João Batista Rocha, Aaron B Bowman, Michael Aschne. Chronic exposure to methylmercury enhances the anorexigenic effects of leptin in C57BL/6J male mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 147. 2021-06-14. PMID:33338554. |
leptin inhibits food intake and decreases body weight through activation of its receptor in the hypothalamus. |
2021-06-14 |
2023-08-13 |
mouse |
| Haofang E Li, Mark A Rossi, Glenn D R Watson, H Gregory Moore, Min Tong Cai, Namsoo Kim, Katrina A Vokt, Dongye Lu, Ryan A Bartholomew, Ryan N Hughes, Henry H Yi. Hypothalamic-Extended Amygdala Circuit Regulates Temporal Discounting. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 9. 2021-06-11. PMID:33441435. |
agouti-related peptide (agrp)-expressing neurons located in the arcuate nucleus of the hypothalamus (arc) regulate food intake and energy homeostasis, yet whether agrp neurons influence choice behavior and temporal discounting is unknown. |
2021-06-11 |
2023-08-13 |
mouse |
| Sandra Aparecida Benite-Ribeiro, Valkíria Alves de Lima Rodrigues, Mônica Rodrigues Ferreira Machad. Food intake in early life and epigenetic modifications of pro-opiomelanocortin expression in arcuate nucleus. Molecular biology reports. vol 48. issue 4. 2021-06-09. PMID:33877530. |
the control of food intake is performed by neurons of the arcuate nucleus of the hypothalamus (arc), which secret orexigenic and anorexigenic neuropeptides, such as proopiomelanocortin (pomc), under stimulation of, e.g., ghrelin, insulin, and leptin. |
2021-06-09 |
2023-08-13 |
Not clear |
| Florent Guillebaud, Manon Duquenne, Mehdi Djelloul, Clément Pierre, Kevin Poirot, Guenièvre Roussel, Seddik Riad, Damien Lanfray, Fabrice Morin, André Jean, Marie-Christine Tonon, Stéphanie Gaigé, Bruno Lebrun, Michel Dallaporta, Jérôme Leprince, Vincent Prevot, Jean-Denis Troade. Glial Endozepines Reverse High-Fat Diet-Induced Obesity by Enhancing Hypothalamic Response to Peripheral Leptin. Molecular neurobiology. vol 57. issue 8. 2021-06-07. PMID:32519243. |
endozepines reversed high fat diet-induced obesity by reducing food intake and restored leptin-induced stat3 phosphorylation in the hypothalamus. |
2021-06-07 |
2023-08-13 |
mouse |
| Kinning Poo. Behavioral Feeding Circuit: Dietary Fat-Induced Effects of Inflammatory Mediators in the Hypothalamus. Frontiers in endocrinology. vol 11. 2021-06-03. PMID:33324346. |
behavioral feeding circuit: dietary fat-induced effects of inflammatory mediators in the hypothalamus. |
2021-06-03 |
2023-08-13 |
Not clear |
| Roldan M de Guia, Anna S Hassing, Louise J Skov, Cecilia Ratner, Kaja Plucińska, Søren Madsen, Thi A Diep, Gelo V Dela Cruz, Samuel A J Trammell, Elahu G Sustarsic, Brice Emanuelli, Matthew P Gillum, Zach Gerhart-Hines, Birgitte Holst, Jonas T Treeba. Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus. Acta physiologica (Oxford, England). vol 228. issue 4. 2021-06-02. PMID:31900990. |
fasting- and ghrelin-induced food intake is regulated by nampt in the hypothalamus. |
2021-06-02 |
2023-08-13 |
Not clear |
| Roldan M de Guia, Anna S Hassing, Louise J Skov, Cecilia Ratner, Kaja Plucińska, Søren Madsen, Thi A Diep, Gelo V Dela Cruz, Samuel A J Trammell, Elahu G Sustarsic, Brice Emanuelli, Matthew P Gillum, Zach Gerhart-Hines, Birgitte Holst, Jonas T Treeba. Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus. Acta physiologica (Oxford, England). vol 228. issue 4. 2021-06-02. PMID:31900990. |
neurons in the arcuate nucleus of the hypothalamus are involved in regulation of food intake and energy expenditure, and dysregulation of signalling in these neurons promotes development of obesity. |
2021-06-02 |
2023-08-13 |
Not clear |
| Jin Yuan, Rongping Zhang, Runze Wu, Yunjuan Gu, Yibing L. The effects of oxytocin to rectify metabolic dysfunction in obese mice are associated with increased thermogenesis. Molecular and cellular endocrinology. vol 514. 2021-06-02. PMID:32531419. |
oxytocin, a protein hormone mainly produced by hypothalamus, has been shown to repress body weight gain in obese animals, in part, by reducing food intake and increasing energy expenditure. |
2021-06-02 |
2023-08-13 |
mouse |
| Iltan Aklan, Nilufer Sayar Atasoy, Yavuz Yavuz, Tayfun Ates, Ilknur Coban, Fulya Koksalar, Gizem Filiz, Iskalen Cansu Topcu, Merve Oncul, Pelin Dilsiz, Utku Cebecioglu, Muhammed Ikbal Alp, Bayram Yilmaz, Deborah R Davis, Karolina Hajdukiewicz, Kenji Saito, Witold Konopka, Huxing Cui, Deniz Ataso. NTS Catecholamine Neurons Mediate Hypoglycemic Hunger via Medial Hypothalamic Feeding Pathways. Cell metabolism. vol 31. issue 2. 2021-06-01. PMID:31839488. |
here, we describe a glucoprivic feeding pathway by tyrosine hydroxylase (th)-expressing neurons from nucleus of solitary tract (nts), which project densely to the hypothalamus and elicit feeding through bidirectional adrenergic modulation of agouti-related peptide (agrp)- and proopiomelanocortin (pomc)-expressing neurons. |
2021-06-01 |
2023-08-13 |
Not clear |
| Verónica Hurtado-Carneiro, Ana Pérez-García, Elvira Alvarez, Carmen San. PAS Kinase: A Nutrient and Energy Sensor "Master Key" in the Response to Fasting/Feeding Conditions. Frontiers in endocrinology. vol 11. 2021-05-21. PMID:33391184. |
this minireview summarizes the pask role in the control of fasting and feeding responses, focusing especially on the hypothalamus and liver. |
2021-05-21 |
2023-08-13 |
mouse |
| Huiling Sun, Kai Meng, Lin Hou, Lijun Shang, Jianqun Ya. Melanocortin receptor-4 mediates the anorectic effect induced by the nucleus tractus solitarius injection of glucagon-like Peptide-2 in fasted rats. European journal of pharmacology. vol 901. 2021-05-18. PMID:33823184. |
recent studies show that the intracerebroventricular administration of glp-2 significantly suppresses food intake in animals and some evidence suggest that the melanocortin receptor-4 (mc4-r) signaling in the hypothalamus is required for intracerebroventricular glp-2-mediated inhibition of feeding. |
2021-05-18 |
2023-08-13 |
rat |
| Vincent Florent, Marc Baroncini, Patrice Jissendi-Tchofo, Renaud Lopes, Matthieu Vanhoutte, Sowmyalakshmi Rasika, Jean-Pierre Pruvo, Jean Vignau, Stephane Verdun, Jeanette E Johansen, Marie Pigeyre, Sebastien G Bouret, Ida A K Nilsson, Vincent Prevo. Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa. Neuroendocrinology. vol 110. issue 6. 2021-05-17. PMID:31484186. |
the hypothalamus contains integrative systems that support life, including physiological processes such as food intake, energy expenditure, and reproduction. |
2021-05-17 |
2023-08-13 |
Not clear |
| Arash Kamali, Farzaneh Ghazi Sherbaf, Farzaneh Rahmani, Mahsa Khayat-Khoei, Azin Aein, Anusha Gandhi, Ekta G Shah, Haris I Sair, Roy F Riascos, Yoshua Esquenazi, Jay-Jiguang Zhu, Zafer Keser, Khader M Hasa. A direct visuosensory cortical connectivity of the human limbic system. Dissecting the trajectory of the parieto-occipito-hypothalamic tract in the human brain using diffusion weighted tractography. Neuroscience letters. vol 728. 2021-05-17. PMID:32278940. |
the hypothalamus plays pivotal roles in controlling autonomic responses and instinctive behaviors such as regulating fear, aggression, learning, feeding behavior, circadian rhythm, and reproductive activities. |
2021-05-17 |
2023-08-13 |
human |
| Hannah Louise Zakariassen, Linu Mary John, Thomas Alexander Lut. Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases. Basic & clinical pharmacology & toxicology. vol 127. issue 3. 2021-05-17. PMID:32363722. |
in particular, signalling via neuronal circuits in the caudal hindbrain and the hypothalamus is implicated in mediating effects on food intake and energy expenditure. |
2021-05-17 |
2023-08-13 |
Not clear |
| Arash Kamali, Niloofar Karbasian, Farzaneh Ghazi Sherbaf, Lindsay A Wilken, Azin Aein, Haris I Sair, Octavio Arevalo Espejo, Pejman Rabiei, Sally J Choi, Saeedeh Mirbagheri, Roy F Riascos, Khader M Hasa. Uncovering the Dorsal Thalamo-hypothalamic Tract of the Human Limbic System. Neuroscience. vol 432. 2021-05-14. PMID:32109529. |
the hypothalamus plays vital roles in the survival of species by regulating fear, learning, feeding behavior, circadian rhythm, sociosexual and reproductive activities of the limbic system through connections with the thalamus. |
2021-05-14 |
2023-08-13 |
human |
| Dan Han, Fang Han, Yuxiu Shi, Shilei Zheng, Lili We. Mechanisms of Memory Impairment Induced by Orexin-A via Orexin 1 and Orexin 2 Receptors in Post-traumatic Stress Disorder Rats. Neuroscience. vol 432. 2021-05-14. PMID:32112915. |
spatial learning and memory in the rats were evaluated with the morris water maze (mwm) test; changes in body weight and food intake were recorded to assess changes in appetite; and the expression of orexin-a and its receptors in the hypothalamus and hippocampus was examined and quantified by immunohistochemistry, western blotting and real-time pcr. |
2021-05-14 |
2023-08-13 |
rat |
| Dan Han, Fang Han, Yuxiu Shi, Shilei Zheng, Lili We. Mechanisms of Memory Impairment Induced by Orexin-A via Orexin 1 and Orexin 2 Receptors in Post-traumatic Stress Disorder Rats. Neuroscience. vol 432. 2021-05-14. PMID:32112915. |
the results showed that spatial memory was impaired and food intake was decreased in sps rats; this was accompanied by downregulation of orexin-a in the hypothalamus and upregulation of ox1r and ox2r in the hippocampus and of ox1r in the hypothalamus. |
2021-05-14 |
2023-08-13 |
rat |