| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| María Inmaculada Navarro García, Rafael González-Costea Martínez, Nuría Torregrosa Pérez, Elena Romera Barba, María Jesús Periago, José Luis Vázquez Roja. Fasting ghrelin levels after gastric bypass and vertical sleeve gastrectomy: An analytic cohort study. Endocrinologia, diabetes y nutricion. vol 67. issue 2. 2021-02-01. PMID:31680051. |
neuronal populations involved in the regulation of food intake, particularly the orexigenic (appetite-stimulating) hormone ghrelin, are found in the hypothalamus. |
2021-02-01 |
2023-08-13 |
Not clear |
| Neruja Loganathan, Emma K McIlwraith, Denise D Belsha. BPA Differentially Regulates NPY Expression in Hypothalamic Neurons Through a Mechanism Involving Oxidative Stress. Endocrinology. vol 161. issue 11. 2021-01-29. PMID:32960947. |
the neuropeptide y (npy) neurons of the hypothalamus control both food intake and reproduction and have emerged as potential targets of bpa. |
2021-01-29 |
2023-08-13 |
Not clear |
| Gwyndolin M Vail, Troy A Roepk. Organophosphate Flame Retardants Excite Arcuate Melanocortin Circuitry and Increase Neuronal Sensitivity to Ghrelin in Adult Mice. Endocrinology. vol 161. issue 11. 2021-01-29. PMID:32961558. |
because feeding behavior and energy expenditure are largely coordinated by the hypothalamus, we hypothesized that opfr disruption of energy homeostasis may occur through edc action on melanocortin circuitry within the arcuate nucleus. |
2021-01-29 |
2023-08-13 |
mouse |
| Felicitas Lopez-Vicchi, Sharon R Ladyman, Ana Maria Ornstein, Papillon Gustafson, Penelope Knowles, Guillermina Maria Luque, David R Grattan, Damasia Becu-Villalobo. Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 3. 2021-01-25. PMID:31944423. |
leptin resistance in obese lacd2rko mice was evidenced by its failure to lower food intake and a dampened response of stat3 phosphorylation, specifically in the mediobasal hypothalamus. |
2021-01-25 |
2023-08-13 |
mouse |
| Jérôme Roy, Laurence Larroquet, Anne Surget, Anthony Lanuque, Franck Sandres, Frederic Terrier, Geneviève Corraze, Jetty Chung-Yung Lee, Sandrine Skiba-Cass. Impact on cerebral function in rainbow trout fed with plant based omega-3 long chain polyunsaturated fatty acids enriched with DHA and EPA. Fish & shellfish immunology. vol 103. 2021-01-25. PMID:32473359. |
ω-3 lc-pufas enrichment decreased daily food intake and induced a simultaneous mrna expression increase in orexigenic transcript npy peptide and a decrease in anorexigen transcript pomca peptide in the hypothalamus. |
2021-01-25 |
2023-08-13 |
Not clear |
| Ana Ortiz-Rodriguez, Maria-Angeles Areval. The Contribution of Astrocyte Autophagy to Systemic Metabolism. International journal of molecular sciences. vol 21. issue 7. 2021-01-13. PMID:32260050. |
astrocytes can sense metabolic signals in the hypothalamus and modulate systemic functions as glucose homeostasis and feeding response. |
2021-01-13 |
2023-08-13 |
Not clear |
| Julien Delezie, Jonathan F Gill, Gesa Santos, Bettina Karrer-Cardel, Christoph Handschi. PGC-1β-expressing POMC neurons mediate the effect of leptin on thermoregulation in the mouse. Scientific reports. vol 10. issue 1. 2021-01-11. PMID:33060645. |
the arcuate nucleus (arc) of the hypothalamus is a key regulator of food intake, brown adipose tissue (bat) thermogenesis, and locomotor activity. |
2021-01-11 |
2023-08-13 |
mouse |
| Stephanie Constanti. Progress and Challenges in the Search for the Mechanisms of Pulsatile Gonadotropin-Releasing Hormone Secretion. Frontiers in endocrinology. vol 8. 2021-01-09. PMID:28790978. |
finally, sex steroids close this axis by feeding back to the hypothalamus. |
2021-01-09 |
2023-08-13 |
Not clear |
| Sunita Sharma, Stephanie Thibodeau, Jonathan Lytto. Signal pathway analysis of selected obesity-associated melanocortin-4 receptor class V mutants. Biochimica et biophysica acta. Molecular basis of disease. vol 1866. issue 8. 2021-01-04. PMID:32423884. |
there is an emerging consensus that gαq-linked signals in the paraventricular nucleus of the hypothalamus are essential for normal satiety and the control of feeding behavior. |
2021-01-04 |
2023-08-13 |
Not clear |
| Yukiko Fu, Kentaro Kaneko, Hsiao-Yun Lin, Qianxing Mo, Yong Xu, Takayoshi Suganami, Peter Ravn, Makoto Fukud. Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus. Endocrinology. vol 161. issue 9. 2021-01-04. PMID:32603429. |
high-fat diet (hfd) feeding increases the gene expression of proinflammatory mediators and decreases insulin actions in the hypothalamus. |
2021-01-04 |
2023-08-13 |
mouse |
| David S Kiss, Istvan Toth, Gergely Jocsak, Tibor Bartha, Laszlo V Frenyo, Zoltan Barany, Tamas L Horvath, Attila Zsarnovszk. Metabolic Lateralization in the Hypothalamus of Male Rats Related to Reproductive and Satiety States. Reproductive sciences (Thousand Oaks, Calif.). vol 27. issue 5. 2020-12-15. PMID:32046448. |
the hypothalamus is the main regulatory center of many homeostatic processes, such as reproduction, food intake, and sleep-wake behavior. |
2020-12-15 |
2023-08-13 |
human |
| David S Kiss, Istvan Toth, Gergely Jocsak, Tibor Bartha, Laszlo V Frenyo, Zoltan Barany, Tamas L Horvath, Attila Zsarnovszk. Metabolic Lateralization in the Hypothalamus of Male Rats Related to Reproductive and Satiety States. Reproductive sciences (Thousand Oaks, Calif.). vol 27. issue 5. 2020-12-15. PMID:32046448. |
the goal of the present study was to trace functional asymmetry of the hypothalamus related to the regulation of food intake and reproduction, in male rodents. |
2020-12-15 |
2023-08-13 |
human |
| Konstantin Yu Moiseev, Polina A Vishnyakova, Valentina V Porseva, Andrey P Masliukov, Andrey A Spirichev, Andrey I Emanuilov, Petr M Masliuko. Changes of nNOS expression in the tuberal hypothalamic nuclei during ageing. Nitric oxide : biology and chemistry. vol 100-101. 2020-12-15. PMID:32283261. |
in conclusion, ageing is accompanied by increasing of nnos expression in the hypothalamus and this process is related to regions involved in the control of feeding behavior. |
2020-12-15 |
2023-08-13 |
rat |
| Noelle Nadermann, Hélène Volkof. Effects of short-term exercise on food intake and the expression of appetite-regulating factors in goldfish. Peptides. vol 123. 2020-12-10. PMID:31678371. |
in this study, we examined the effects of short-term (30 min, at low and high water flow) exercise on food intake, glucose levels and the expressions of appetite regulators in goldfish hypothalamus (irisin, orexin, cart, leptin), intestine (cck, pyy, proglucagon/glp-1), muscle (irisin) and liver (leptin), of brain-derived neurotrophic factor (bdnf) in brain, interleukin-6 (il6) in muscle and hypothalamus, and major metabolic enzymes, the glycolytic enzyme glucokinase (gck) and its regulatory protein (gckr) in liver, the lipolytic enzyme lipoprotein lipase in intestine and muscle, and trypsin in intestine. |
2020-12-10 |
2023-08-13 |
Not clear |
| Nicola J Lee, Yue Qi, Ronaldo F Enriquez, Chi Kin Ip, Herbert Herzo. Lack of NPY in neurotensin neurons leads to a lean phenotype. Neuropeptides. vol 80. 2020-12-10. PMID:31740068. |
neuropeptide y (npy) producing neurons in the arcuate nucleus (arc) of the hypothalamus are essential to the regulation of food intake and energy homeostasis. |
2020-12-10 |
2023-08-13 |
Not clear |
| Chan Hee Lee, Do Kyeong Song, Chae Beom Park, Jeewon Choi, Gil Myoung Kang, Sung Hoon Shin, Ijoo Kwon, Soyoung Park, Seongjun Kim, Ji Ye Kim, Hong Dugu, Jae Woo Park, Jong Han Choi, Se Hee Min, Jong-Woo Sohn, Min-Seon Ki. Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus. Nature communications. vol 11. issue 1. 2020-11-24. PMID:33188191. |
notably, maternal nutrition and postnatal leptin surge have a profound impact on ciliogenesis in the hypothalamus of neonatal mice; through these effects they critically modulate the organization of hypothalamic feeding circuits. |
2020-11-24 |
2023-08-13 |
mouse |
| Ehsan Pashay Ahi, Mathilde Brunel, Emmanouil Tsakoumis, Monika Schmit. Transcriptional study of appetite regulating genes in the brain of zebrafish (Danio rerio) with impaired leptin signalling. Scientific reports. vol 9. issue 1. 2020-11-16. PMID:31882937. |
in mammals, leptin acts as an anorexigen and inhibits food intake centrally by affecting the appetite centres in the hypothalamus. |
2020-11-16 |
2023-08-13 |
zebrafish |
| Morgane Baron, Philippe Froguel, Amélie Bonnefon. [Something new in the genetics of monogenic obesity and its insights into pathophysiology]. Medecine sciences : M/S. vol 36. issue 10. 2020-11-12. PMID:33026327. |
so far, the genes that have been found to be mutated in these monogenic forms play a key role in the leptin/melanocortin pathway which is mainly active in the hypothalamus and which regulates food intake and energy expenditure. |
2020-11-12 |
2023-08-13 |
Not clear |
| Yuko Maejima, Shigeki Kato, Shoichiro Horita, Yoichi Ueta, Seiichi Takenoshita, Kazuto Kobayashi, Kenju Shimomur. The hypothalamus to brainstem circuit suppresses late-onset body weight gain. Scientific reports. vol 9. issue 1. 2020-11-10. PMID:31798010. |
regarding such mechanisms in the brain, we here report that neural circuits from the hypothalamus (paraventricular nucleus: pvn) to the brainstem (dorsal vagal complex: dvc) suppress late-onset bw gain without affecting food intake. |
2020-11-10 |
2023-08-13 |
rat |
| Hongyang Yao, Chaonan Fan, Xiuqin Fan, Yuanyuan Lu, Yuanyuan Wang, Rui Wang, Tiantian Tang, Kemin Q. Effects of gut microbiota on leptin expression and body weight are lessened by high-fat diet in mice. The British journal of nutrition. vol 124. issue 4. 2020-11-04. PMID:32213218. |
adipose or hepatic expression of genes associated with fat synthesis (acc1, fas and srebp-1c), hydrolysis and oxidation (atgl, cpt1a, cpt1c, ppar-α and pgc-1α) was lower, and hypothalamus expression of pomc and socs3 was higher in gf mice than levels in cv mice, particularly with nfd feeding. |
2020-11-04 |
2023-08-13 |
mouse |