| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tiantian Zhang, Yizhe Chen, Jiarui Cai, Miao Pan, Qian Sun, Jing Zhang, Chao Su. SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. Oxidative medicine and cellular longevity. vol 2020. 2021-05-14. PMID:32733634. |
leptin could inhibit food intake and increase thermogenesis through leptin receptor (lepr), which was present in the hypothalamus and certain peripheral organs, including adipose tissue. |
2021-05-14 |
2023-08-13 |
mouse |
| Agnieszka Irena Mazur-Bial. Asprosin-A Fasting-Induced, Glucogenic, and Orexigenic Adipokine as a New Promising Player. Will It Be a New Factor in the Treatment of Obesity, Diabetes, or Infertility? A Review of the Literature. Nutrients. vol 13. issue 2. 2021-05-14. PMID:33673009. |
as it crosses the blood-brain barrier, it also acts as an orexigenic peptide that stimulates food intake through activation of agrp neurons in the hypothalamus; thus, asprosin participates in maintaining the body's energy homeostasis. |
2021-05-14 |
2023-08-13 |
mouse |
| Junta Imai, Hideki Katagir. Regulation of systemic metabolism by the autonomic nervous system consisting of afferent and efferent innervation. International immunology. 2021-05-13. PMID:33982088. |
vagal afferent nerves receive signals, such as nutrients and hormones, from the peripheral organs/tissues including the gastrointestinal tract and adipose tissue then transmit these signals to the hypothalamus, thereby regulating feeding behavior. |
2021-05-13 |
2023-08-13 |
Not clear |
| Melanie Spindler, Jale Özyurt, Christiane M Thie. Automated diffusion-based parcellation of the hypothalamus reveals subunit-specific associations with obesity. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335266. |
the hypothalamus is a small, yet highly versatile structure mainly involved in bodily functions such as control of food intake and endocrine activity. |
2021-05-10 |
2023-08-13 |
human |
| Zhengzhi Tian, Shaoqi Xu, Mei Wang, Ya Li, Hu Chen, Ni Tang, Bin Wang, Xin Zhang, Zhiqiong L. Identification, tissue distribution, periprandial expression, and anorexigenic effect of spexin in Siberian sturgeon, Acipenser baeri. Fish physiology and biochemistry. vol 46. issue 6. 2021-05-07. PMID:32794103. |
the expression of spexin mrna in the hypothalamus was significantly increased after food intake. |
2021-05-07 |
2023-08-13 |
Not clear |
| Cheng Ye, Shaohua Xu, Qiongyao Hu, Minqiang Hu, Lingling Zhou, Xiangfeng Qin, Jingyi Jia, Guangfu H. Structure and function analysis of various brain subregions and pituitary in grass carp (Ctenopharyngodon idellus). Comparative biochemistry and physiology. Part D, Genomics & proteomics. vol 33. 2021-05-04. PMID:31923798. |
the hypothalamus could regulate feeding, and reproduction process. |
2021-05-04 |
2023-08-13 |
Not clear |
| E Alvarez-Salas, F Gama, G Matamoros-Trejo, M I Amaya, P de Gortar. TRH in the nucleus accumbens acts downstream to α-MSH to decrease food intake in rats. Neuroscience letters. vol 739. 2021-04-30. PMID:32980456. |
feeding-regulatory peptides such as thyrotropin-releasing hormone (trh), α-melanocyte-stimulating hormone (α-msh) and their receptors are expressed in brain regions involved in the homeostatic and hedonic control of food intake, such as the hypothalamus and the mesolimbic system, respectively. |
2021-04-30 |
2023-08-13 |
rat |
| Natália Ferreira Mendes, Carlos Poblete Jara, Ariane Maria Zanesco, Eliana Pereira de Araúj. Hypothalamic Microglial Heterogeneity and Signature under High Fat Diet-Induced Inflammation. International journal of molecular sciences. vol 22. issue 5. 2021-04-29. PMID:33668314. |
under high-fat feeding, the hypothalamus atypically undergoes pro-inflammatory signaling activation. |
2021-04-29 |
2023-08-13 |
Not clear |
| Irina V Milanova, Felipe Correa-da-Silva, Andries Kalsbeek, Chun-Xia Y. Mapping of Microglial Brain Region, Sex and Age Heterogeneity in Obesity. International journal of molecular sciences. vol 22. issue 6. 2021-04-28. PMID:33808700. |
the hypothalamus is a key brain region involved in the regulation of food intake and energy expenditure. |
2021-04-28 |
2023-08-13 |
Not clear |
| Guilherme Nogueira, Carina Solon, Rodrigo S Carraro, Daiane F Engel, Albina F Ramalho, Davi Sidarta-Oliveira, Rodrigo S Gaspar, Bruna Bombassaro, Ana C Vasques, Bruno Geloneze, Marco A Vinolo, Jose Donato Junior, Licio A Vellos. Interleukin-17 acts in the hypothalamus reducing food intake. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:31863824. |
interleukin-17 acts in the hypothalamus reducing food intake. |
2021-04-27 |
2023-08-13 |
mouse |
| Guilherme Nogueira, Carina Solon, Rodrigo S Carraro, Daiane F Engel, Albina F Ramalho, Davi Sidarta-Oliveira, Rodrigo S Gaspar, Bruna Bombassaro, Ana C Vasques, Bruno Geloneze, Marco A Vinolo, Jose Donato Junior, Licio A Vellos. Interleukin-17 acts in the hypothalamus reducing food intake. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:31863824. |
here, we hypothesized that, similar to several other gut-produced factors, il-17 may act in the hypothalamus to modulate food intake. |
2021-04-27 |
2023-08-13 |
mouse |
| Guilherme Nogueira, Carina Solon, Rodrigo S Carraro, Daiane F Engel, Albina F Ramalho, Davi Sidarta-Oliveira, Rodrigo S Gaspar, Bruna Bombassaro, Ana C Vasques, Bruno Geloneze, Marco A Vinolo, Jose Donato Junior, Licio A Vellos. Interleukin-17 acts in the hypothalamus reducing food intake. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:31863824. |
thus, il-17 is a gut-produced factor that is controlled by diet and modulates food intake by acting in the hypothalamus. |
2021-04-27 |
2023-08-13 |
mouse |
| Shi-Bin Li, Luis de Lece. The hypocretin (orexin) system: from a neural circuitry perspective. Neuropharmacology. vol 167. 2021-04-23. PMID:32135427. |
hypocretin/orexin neurons are distributed restrictively in the hypothalamus, a brain region known to orchestrate diverse functions including sleep, reward processing, food intake, thermogenesis, and mood. |
2021-04-23 |
2023-08-13 |
Not clear |
| Abhilash Prabhat, Twinkle Batra, Vinod Kuma. Effects of timed food availability on reproduction and metabolism in zebra finches: Molecular insights into homeostatic adaptation to food-restriction in diurnal vertebrates. Hormones and behavior. vol 125. 2021-04-20. PMID:32710887. |
however, genes coding for the deiodinases (dio2, dio3) and gonadotropin inhibiting hormone (gnih) showed no difference between feeding conditions in both hypothalamus and testes. |
2021-04-20 |
2023-08-13 |
Not clear |
| Adrián Díaz-Rúa, Mauro Chivite, Sara Comesaña, Cristina Velasco, Luisa M P Valente, José L Soengas, Marta Conde-Sieir. The endocannabinoid system is affected by a high-fat-diet in rainbow trout. Hormones and behavior. vol 125. 2021-04-20. PMID:32771417. |
then, we evaluated the postprandial response (1, 3 and 6 h) of components of the ecs in plasma, hypothalamus, and telencephalon after feeding fish with cd and hfd. |
2021-04-20 |
2023-08-13 |
Not clear |
| Shiying Li, Yeram Kim, Jiande D Z Chen, Mohammad F Madhou. Intestinal Electrical Stimulation Alters Hypothalamic Expression of Oxytocin and Orexin and Ameliorates Diet-Induced Obesity in Rats. Obesity surgery. vol 31. issue 4. 2021-04-19. PMID:33392995. |
the aim of this study was to explore the central mechanism underlying the reduction of food intake and body weight by ies by studying the expression of anorexigenic- and orexigenic-peptide-containing neurons in the hypothalamus. |
2021-04-19 |
2023-08-13 |
rat |
| Denise D Belsham, Prasad S Dalv. Insulin signalling in hypothalamic neurones. Journal of neuroendocrinology. vol 33. issue 4. 2021-04-16. PMID:33227171. |
the hypothalamus is a key region in the brain that responds to circulating insulin by engaging a complex signalling cascade resulting in the ultimate release of neuropeptides that control hunger and feeding. |
2021-04-16 |
2023-08-13 |
Not clear |
| Yolanda Diz-Chaves, Salvador Herrera-Pérez, Lucas C González-Matías, José Antonio Lamas, Federico Mall. Glucagon-Like Peptide-1 (GLP-1) in the Integration of Neural and Endocrine Responses to Stress. Nutrients. vol 12. issue 11. 2021-04-15. PMID:33126672. |
these neurons project to the hypothalamus and another forebrain, hindbrain, and mesolimbic brain areas control the autonomic function, feeding, and the motivation to feed or regulate the stress response and the hypothalamic-pituitary-adrenal axis. |
2021-04-15 |
2023-08-13 |
Not clear |
| Atsuki Kadota, Eiko Iwakoshi-Ukena, Keisuke Fukumura, Kenshiro Shikano, Yuki Narimatsu, Megumi Furumitsu, Kazuyoshi Uken. Effects of Irregular Feeding on the Daily Fluctuations in mRNA Expression of the Neurosecretory Protein GL and Neurosecretory Protein GM Genes in the Mouse Hypothalamus. International journal of molecular sciences. vol 22. issue 4. 2021-04-14. PMID:33672695. |
effects of irregular feeding on the daily fluctuations in mrna expression of the neurosecretory protein gl and neurosecretory protein gm genes in the mouse hypothalamus. |
2021-04-14 |
2023-08-13 |
mouse |
| D Valent, L Arroyo, E Fàbrega, M Font-I-Furnols, M Rodríguez-Palmero, J A Moreno-Muñoz, J Tibau, A Bassol. Effects of a high-fat-diet supplemented with probiotics and ω3-fatty acids on appetite regulatory neuropeptides and neurotransmitters in a pig model. Beneficial microbes. vol 11. issue 4. 2021-04-13. PMID:32720835. |
the hypothalamus is the central part of the brain that regulates food intake by means of the production of food intake-regulatory hypothalamic neuropeptides, as neuropeptide y (npy), orexin a and pro-opiomelanocortin (pomc), and neurotransmitters, such as dopamine and serotonin. |
2021-04-13 |
2023-08-13 |
Not clear |